{"id":"https://openalex.org/W2970833521","doi":"https://doi.org/10.1109/tcbb.2019.2937774","title":"LWPCMF: Logistic Weighted Profile-Based Collaborative Matrix Factorization for Predicting MiRNA-Disease Associations","display_name":"LWPCMF: Logistic Weighted Profile-Based Collaborative Matrix Factorization for Predicting MiRNA-Disease Associations","publication_year":2019,"publication_date":"2019-08-28","ids":{"openalex":"https://openalex.org/W2970833521","doi":"https://doi.org/10.1109/tcbb.2019.2937774","mag":"2970833521","pmid":"https://pubmed.ncbi.nlm.nih.gov/31478868"},"language":"en","primary_location":{"id":"doi:10.1109/tcbb.2019.2937774","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tcbb.2019.2937774","pdf_url":null,"source":{"id":"https://openalex.org/S36029991","display_name":"IEEE/ACM Transactions on Computational Biology and Bioinformatics","issn_l":"1545-5963","issn":["1545-5963","1557-9964","2374-0043"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE/ACM Transactions on Computational Biology and Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5018925936","display_name":"Meng-Meng Yin","orcid":"https://orcid.org/0000-0001-6143-023X"},"institutions":[{"id":"https://openalex.org/I202126657","display_name":"Qufu Normal University","ror":"https://ror.org/03ceheh96","country_code":"CN","type":"education","lineage":["https://openalex.org/I202126657"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Meng-Meng Yin","raw_affiliation_strings":["School of Information Science and Engineering, Qufu Normal University, Rizhao, Shandong, China"],"raw_orcid":"https://orcid.org/0000-0001-6143-023X","affiliations":[{"raw_affiliation_string":"School of Information Science and Engineering, Qufu Normal University, Rizhao, Shandong, China","institution_ids":["https://openalex.org/I202126657"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058029547","display_name":"Zhen Cui","orcid":"https://orcid.org/0000-0001-5522-6750"},"institutions":[{"id":"https://openalex.org/I202126657","display_name":"Qufu Normal University","ror":"https://ror.org/03ceheh96","country_code":"CN","type":"education","lineage":["https://openalex.org/I202126657"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhen Cui","raw_affiliation_strings":["School of Information Science and Engineering, Qufu Normal University, Rizhao, Shandong, China"],"raw_orcid":"https://orcid.org/0000-0001-5522-6750","affiliations":[{"raw_affiliation_string":"School of Information Science and Engineering, Qufu Normal University, Rizhao, Shandong, China","institution_ids":["https://openalex.org/I202126657"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086778639","display_name":"Mingming Gao","orcid":null},"institutions":[{"id":"https://openalex.org/I202126657","display_name":"Qufu Normal University","ror":"https://ror.org/03ceheh96","country_code":"CN","type":"education","lineage":["https://openalex.org/I202126657"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ming-Ming Gao","raw_affiliation_strings":["School of Information Science and Engineering, Qufu Normal University, Rizhao, Shandong, China"],"raw_orcid":"https://orcid.org/0000-0002-2614-2600","affiliations":[{"raw_affiliation_string":"School of Information Science and Engineering, Qufu Normal University, Rizhao, Shandong, China","institution_ids":["https://openalex.org/I202126657"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073144090","display_name":"Jin\u2010Xing Liu","orcid":"https://orcid.org/0000-0001-6104-2149"},"institutions":[{"id":"https://openalex.org/I202126657","display_name":"Qufu Normal University","ror":"https://ror.org/03ceheh96","country_code":"CN","type":"education","lineage":["https://openalex.org/I202126657"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jin-Xing Liu","raw_affiliation_strings":["School of Information Science and Engineering, Qufu Normal University, Rizhao, Shandong, China"],"raw_orcid":"https://orcid.org/0000-0001-6104-2149","affiliations":[{"raw_affiliation_string":"School of Information Science and Engineering, Qufu Normal University, Rizhao, Shandong, China","institution_ids":["https://openalex.org/I202126657"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5026569643","display_name":"Ying-Lian Gao","orcid":"https://orcid.org/0000-0003-0483-5622"},"institutions":[{"id":"https://openalex.org/I202126657","display_name":"Qufu Normal University","ror":"https://ror.org/03ceheh96","country_code":"CN","type":"education","lineage":["https://openalex.org/I202126657"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ying-Lian Gao","raw_affiliation_strings":["Library of Qufu Normal University, Qufu Normal University, Rizhao, Shandong, China"],"raw_orcid":"https://orcid.org/0000-0003-0483-5622","affiliations":[{"raw_affiliation_string":"Library of Qufu Normal University, Qufu Normal University, Rizhao, Shandong, China","institution_ids":["https://openalex.org/I202126657"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5018925936"],"corresponding_institution_ids":["https://openalex.org/I202126657"],"apc_list":null,"apc_paid":null,"fwci":1.7579,"has_fulltext":false,"cited_by_count":27,"citation_normalized_percentile":{"value":0.8369906,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":99},"biblio":{"volume":"18","issue":"3","first_page":"1122","last_page":"1129"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10515","display_name":"Cancer-related molecular mechanisms research","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11765","display_name":"Circular RNAs in diseases","score":0.9959999918937683,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/logistic-regression","display_name":"Logistic regression","score":0.6407970190048218},{"id":"https://openalex.org/keywords/similarity","display_name":"Similarity (geometry)","score":0.5965718030929565},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5828785300254822},{"id":"https://openalex.org/keywords/kernel","display_name":"Kernel (algebra)","score":0.5663251280784607},{"id":"https://openalex.org/keywords/matrix-decomposition","display_name":"Matrix decomposition","score":0.5520595908164978},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.5044847726821899},{"id":"https://openalex.org/keywords/non-negative-matrix-factorization","display_name":"Non-negative matrix factorization","score":0.4998347759246826},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.48084816336631775},{"id":"https://openalex.org/keywords/function","display_name":"Function (biology)","score":0.4742164611816406},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.41460949182510376},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.39945539832115173},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.2990010380744934},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.0925615131855011}],"concepts":[{"id":"https://openalex.org/C151956035","wikidata":"https://www.wikidata.org/wiki/Q1132755","display_name":"Logistic regression","level":2,"score":0.6407970190048218},{"id":"https://openalex.org/C103278499","wikidata":"https://www.wikidata.org/wiki/Q254465","display_name":"Similarity (geometry)","level":3,"score":0.5965718030929565},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5828785300254822},{"id":"https://openalex.org/C74193536","wikidata":"https://www.wikidata.org/wiki/Q574844","display_name":"Kernel (algebra)","level":2,"score":0.5663251280784607},{"id":"https://openalex.org/C42355184","wikidata":"https://www.wikidata.org/wiki/Q1361088","display_name":"Matrix decomposition","level":3,"score":0.5520595908164978},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.5044847726821899},{"id":"https://openalex.org/C152671427","wikidata":"https://www.wikidata.org/wiki/Q10843505","display_name":"Non-negative matrix factorization","level":4,"score":0.4998347759246826},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.48084816336631775},{"id":"https://openalex.org/C14036430","wikidata":"https://www.wikidata.org/wiki/Q3736076","display_name":"Function (biology)","level":2,"score":0.4742164611816406},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.41460949182510376},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.39945539832115173},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.2990010380744934},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0925615131855011},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C115961682","wikidata":"https://www.wikidata.org/wiki/Q860623","display_name":"Image (mathematics)","level":2,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C78458016","wikidata":"https://www.wikidata.org/wiki/Q840400","display_name":"Evolutionary biology","level":1,"score":0.0},{"id":"https://openalex.org/C158693339","wikidata":"https://www.wikidata.org/wiki/Q190524","display_name":"Eigenvalues and eigenvectors","level":2,"score":0.0},{"id":"https://openalex.org/C114614502","wikidata":"https://www.wikidata.org/wiki/Q76592","display_name":"Combinatorics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016015","descriptor_name":"Logistic Models","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016015","descriptor_name":"Logistic Models","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016015","descriptor_name":"Logistic Models","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020022","descriptor_name":"Genetic Predisposition to Disease","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D020022","descriptor_name":"Genetic Predisposition to Disease","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D020022","descriptor_name":"Genetic Predisposition to Disease","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1109/tcbb.2019.2937774","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tcbb.2019.2937774","pdf_url":null,"source":{"id":"https://openalex.org/S36029991","display_name":"IEEE/ACM Transactions on Computational Biology and Bioinformatics","issn_l":"1545-5963","issn":["1545-5963","1557-9964","2374-0043"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE/ACM Transactions on Computational Biology and Bioinformatics","raw_type":"journal-article"},{"id":"pmid:31478868","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31478868","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE/ACM transactions on computational biology and bioinformatics","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Decent work and economic growth","score":0.5600000023841858,"id":"https://metadata.un.org/sdg/8"}],"awards":[{"id":"https://openalex.org/G5609717784","display_name":null,"funder_award_id":"61872220","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G5860415692","display_name":null,"funder_award_id":"61572284","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":47,"referenced_works":["https://openalex.org/W36493179","https://openalex.org/W1667789979","https://openalex.org/W1763867024","https://openalex.org/W2033180984","https://openalex.org/W2038122249","https://openalex.org/W2042484777","https://openalex.org/W2047967134","https://openalex.org/W2062290101","https://openalex.org/W2082500464","https://openalex.org/W2083045667","https://openalex.org/W2090335107","https://openalex.org/W2098318517","https://openalex.org/W2118814218","https://openalex.org/W2119687825","https://openalex.org/W2122211092","https://openalex.org/W2124007301","https://openalex.org/W2126619650","https://openalex.org/W2128768066","https://openalex.org/W2130281728","https://openalex.org/W2131900960","https://openalex.org/W2132694427","https://openalex.org/W2138664009","https://openalex.org/W2141222510","https://openalex.org/W2142937131","https://openalex.org/W2146292498","https://openalex.org/W2151519667","https://openalex.org/W2153838454","https://openalex.org/W2158135353","https://openalex.org/W2180078914","https://openalex.org/W2200926758","https://openalex.org/W2343107734","https://openalex.org/W2410390867","https://openalex.org/W2511620854","https://openalex.org/W2584926544","https://openalex.org/W2752131265","https://openalex.org/W2757038198","https://openalex.org/W2765907185","https://openalex.org/W2793951981","https://openalex.org/W2795540478","https://openalex.org/W2912279798","https://openalex.org/W2996975828","https://openalex.org/W3006845127","https://openalex.org/W3012154856","https://openalex.org/W3013787003","https://openalex.org/W6601490017","https://openalex.org/W6637326655","https://openalex.org/W6638057232"],"related_works":["https://openalex.org/W2127243424","https://openalex.org/W2037504162","https://openalex.org/W2792706544","https://openalex.org/W1568451138","https://openalex.org/W2539013788","https://openalex.org/W2156699640","https://openalex.org/W2045265907","https://openalex.org/W2075222291","https://openalex.org/W2146544734","https://openalex.org/W4287022770"],"abstract_inverted_index":{"As":[0],"is":[1,12,55,64,82,88,151,191,199],"known":[2,115,177],"to":[3,7,24,71,90,100,132,142,153,166,201],"all,":[4],"constructing":[5],"experiments":[6],"predict":[8,25,202],"unknown":[9],"miRNA-disease":[10,27,204],"association":[11],"time-consuming,":[13],"laborious":[14],"and":[15,39,95,111,128,137],"costly.":[16],"Accordingly,":[17],"new":[18,45],"prediction":[19],"model":[20,47,198],"should":[21,36],"be":[22,37,118],"conducted":[23,165],"novel":[26],"associations.":[28,205],"What's":[29],"more,":[30],"the":[31,73,79,105,114,155,168,185],"performance":[32,74],"of":[33,75,126,158],"this":[34,42,59,76,159],"method":[35,190],"high":[38],"reliable.":[40],"In":[41,58,84],"paper,":[43],"a":[44,147],"computation":[46],"Logistic":[48],"Weighted":[49],"Profile-based":[50],"Collaborative":[51],"Matrix":[52],"Factorization":[53],"(LWPCMF)":[54],"put":[56],"forward.":[57],"method,":[60],"weighted":[61],"profile":[62],"(WP)":[63],"combined":[65],"with":[66],"collaborative":[67],"matrix":[68,94,99],"factorization":[69],"(CMF)":[70],"increase":[72],"model.":[77],"And,":[78,120,184],"neighbor":[80],"information":[81],"considered.":[83],"addition,":[85],"logistic":[86,112],"function":[87],"applied":[89],"miRNA":[91,133],"functional":[92,134],"similarity":[93,98,135,140],"disease":[96,138],"semantic":[97,139],"extract":[101],"valuable":[102],"information.":[103],"At":[104],"same":[106],"time,":[107],"by":[108],"adding":[109],"WP":[110],"function,":[113],"correlation":[116],"can":[117],"protected.":[119],"Gaussian":[121],"Interaction":[122],"Profile":[123],"(GIP)":[124],"kernels":[125],"miRNAs":[127],"diseases":[129],"are":[130,164],"added":[131],"network":[136,141],"augment":[143],"kernel":[144],"similarities.":[145],"Then,":[146],"five-fold":[148],"cross":[149],"validation":[150],"implemented":[152],"evaluate":[154],"predictive":[156],"ability":[157],"method.":[160],"Besides,":[161],"case":[162],"studies":[163],"view":[167],"experimental":[169],"results.":[170],"The":[171],"final":[172],"result":[173,186],"contains":[174],"not":[175],"only":[176],"associations":[178],"but":[179],"also":[180],"newly":[181],"predicted":[182],"ones.":[183],"proves":[187],"that":[188],"our":[189],"better":[192],"than":[193],"other":[194],"existing":[195],"methods.":[196],"This":[197],"able":[200],"potential":[203]},"counts_by_year":[{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":12},{"year":2019,"cited_by_count":1}],"updated_date":"2026-03-27T05:58:40.876381","created_date":"2025-10-10T00:00:00"}