{"id":"https://openalex.org/W2960235084","doi":"https://doi.org/10.1109/tcbb.2019.2926716","title":"MCHMDA:Predicting Microbe-Disease Associations Based on Similarities and Low-Rank Matrix Completion","display_name":"MCHMDA:Predicting Microbe-Disease Associations Based on Similarities and Low-Rank Matrix Completion","publication_year":2019,"publication_date":"2019-07-10","ids":{"openalex":"https://openalex.org/W2960235084","doi":"https://doi.org/10.1109/tcbb.2019.2926716","mag":"2960235084","pmid":"https://pubmed.ncbi.nlm.nih.gov/31295117"},"language":"en","primary_location":{"id":"doi:10.1109/tcbb.2019.2926716","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tcbb.2019.2926716","pdf_url":null,"source":{"id":"https://openalex.org/S36029991","display_name":"IEEE/ACM Transactions on Computational Biology and Bioinformatics","issn_l":"1545-5963","issn":["1545-5963","1557-9964","2374-0043"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE/ACM Transactions on Computational Biology and Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100613014","display_name":"Cheng Yan","orcid":"https://orcid.org/0000-0002-5021-6841"},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]},{"id":"https://openalex.org/I4210167317","display_name":"Qiannan Normal College For Nationalities","ror":"https://ror.org/05szpc322","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210167317"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Cheng Yan","raw_affiliation_strings":["School of Computer Science and Engineering, Central South University, Changsha, Hunan, China","School of Computer and Information, Qiannan Normal University for Nationalities, Duyun, Guizhou, China"],"raw_orcid":"https://orcid.org/0000-0002-5021-6841","affiliations":[{"raw_affiliation_string":"School of Computer Science and Engineering, Central South University, Changsha, Hunan, China","institution_ids":["https://openalex.org/I139660479"]},{"raw_affiliation_string":"School of Computer and Information, Qiannan Normal University for Nationalities, Duyun, Guizhou, China","institution_ids":["https://openalex.org/I4210167317"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026877800","display_name":"Guihua Duan","orcid":"https://orcid.org/0000-0002-9406-6443"},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Guihua Duan","raw_affiliation_strings":["School of Computer Science and Engineering, Central South University, Changsha, Hunan, China"],"raw_orcid":"https://orcid.org/0000-0002-9406-6443","affiliations":[{"raw_affiliation_string":"School of Computer Science and Engineering, Central South University, Changsha, Hunan, China","institution_ids":["https://openalex.org/I139660479"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091157395","display_name":"Fang\u2010Xiang Wu","orcid":"https://orcid.org/0000-0002-4593-9332"},"institutions":[{"id":"https://openalex.org/I32625721","display_name":"University of Saskatchewan","ror":"https://ror.org/010x8gc63","country_code":"CA","type":"education","lineage":["https://openalex.org/I32625721"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Fang-Xiang Wu","raw_affiliation_strings":["University of Saskatchewan, Saskatoon, SK, Canada"],"raw_orcid":"https://orcid.org/0000-0002-4593-9332","affiliations":[{"raw_affiliation_string":"University of Saskatchewan, Saskatoon, SK, Canada","institution_ids":["https://openalex.org/I32625721"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101465265","display_name":"Yi Pan","orcid":"https://orcid.org/0000-0002-2766-3096"},"institutions":[{"id":"https://openalex.org/I181565077","display_name":"Georgia State University","ror":"https://ror.org/03qt6ba18","country_code":"US","type":"education","lineage":["https://openalex.org/I181565077"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yi Pan","raw_affiliation_strings":["Georgia State University, Atlanta, GA, USA"],"raw_orcid":"https://orcid.org/0000-0002-2766-3096","affiliations":[{"raw_affiliation_string":"Georgia State University, Atlanta, GA, USA","institution_ids":["https://openalex.org/I181565077"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100438360","display_name":"Jianxin Wang","orcid":"https://orcid.org/0000-0003-1516-0480"},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jianxin Wang","raw_affiliation_strings":["School of Computer Science and Engineering, Central South University, Changsha, Hunan, China"],"raw_orcid":"https://orcid.org/0000-0003-1516-0480","affiliations":[{"raw_affiliation_string":"School of Computer Science and Engineering, Central South University, Changsha, Hunan, China","institution_ids":["https://openalex.org/I139660479"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.2136,"has_fulltext":false,"cited_by_count":35,"citation_normalized_percentile":{"value":0.78751837,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":99},"biblio":{"volume":"18","issue":"2","first_page":"611","last_page":"620"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.9958000183105469,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.9958000183105469,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.9909999966621399,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9736999869346619,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/similarity","display_name":"Similarity (geometry)","score":0.7961527705192566},{"id":"https://openalex.org/keywords/disease","display_name":"Disease","score":0.6852428913116455},{"id":"https://openalex.org/keywords/association","display_name":"Association (psychology)","score":0.5795756578445435},{"id":"https://openalex.org/keywords/rank","display_name":"Rank (graph theory)","score":0.5474683046340942},{"id":"https://openalex.org/keywords/matrix-completion","display_name":"Matrix completion","score":0.5300202965736389},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.5059470534324646},{"id":"https://openalex.org/keywords/benchmark","display_name":"Benchmark (surveying)","score":0.500105619430542},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.49031832814216614},{"id":"https://openalex.org/keywords/cross-validation","display_name":"Cross-validation","score":0.46519148349761963},{"id":"https://openalex.org/keywords/jaccard-index","display_name":"Jaccard index","score":0.4330523908138275},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.42255210876464844},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.3961026072502136},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.3613390028476715},{"id":"https://openalex.org/keywords/gaussian","display_name":"Gaussian","score":0.34289315342903137},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.3370976150035858},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.2558492422103882},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.25529325008392334},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.23437172174453735},{"id":"https://openalex.org/keywords/geography","display_name":"Geography","score":0.09024178981781006},{"id":"https://openalex.org/keywords/pathology","display_name":"Pathology","score":0.08569833636283875},{"id":"https://openalex.org/keywords/psychology","display_name":"Psychology","score":0.07680359482765198}],"concepts":[{"id":"https://openalex.org/C103278499","wikidata":"https://www.wikidata.org/wiki/Q254465","display_name":"Similarity (geometry)","level":3,"score":0.7961527705192566},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.6852428913116455},{"id":"https://openalex.org/C142853389","wikidata":"https://www.wikidata.org/wiki/Q744778","display_name":"Association (psychology)","level":2,"score":0.5795756578445435},{"id":"https://openalex.org/C164226766","wikidata":"https://www.wikidata.org/wiki/Q7293202","display_name":"Rank (graph theory)","level":2,"score":0.5474683046340942},{"id":"https://openalex.org/C2778459887","wikidata":"https://www.wikidata.org/wiki/Q6787865","display_name":"Matrix completion","level":3,"score":0.5300202965736389},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.5059470534324646},{"id":"https://openalex.org/C185798385","wikidata":"https://www.wikidata.org/wiki/Q1161707","display_name":"Benchmark (surveying)","level":2,"score":0.500105619430542},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.49031832814216614},{"id":"https://openalex.org/C27181475","wikidata":"https://www.wikidata.org/wiki/Q541014","display_name":"Cross-validation","level":2,"score":0.46519148349761963},{"id":"https://openalex.org/C203519979","wikidata":"https://www.wikidata.org/wiki/Q865360","display_name":"Jaccard index","level":3,"score":0.4330523908138275},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.42255210876464844},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.3961026072502136},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.3613390028476715},{"id":"https://openalex.org/C163716315","wikidata":"https://www.wikidata.org/wiki/Q901177","display_name":"Gaussian","level":2,"score":0.34289315342903137},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.3370976150035858},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.2558492422103882},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.25529325008392334},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.23437172174453735},{"id":"https://openalex.org/C205649164","wikidata":"https://www.wikidata.org/wiki/Q1071","display_name":"Geography","level":0,"score":0.09024178981781006},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.08569833636283875},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.07680359482765198},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C115961682","wikidata":"https://www.wikidata.org/wiki/Q860623","display_name":"Image (mathematics)","level":2,"score":0.0},{"id":"https://openalex.org/C114614502","wikidata":"https://www.wikidata.org/wiki/Q76592","display_name":"Combinatorics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C542102704","wikidata":"https://www.wikidata.org/wiki/Q183257","display_name":"Psychotherapist","level":1,"score":0.0},{"id":"https://openalex.org/C13280743","wikidata":"https://www.wikidata.org/wiki/Q131089","display_name":"Geodesy","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D015233","descriptor_name":"Models, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015233","descriptor_name":"Models, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015233","descriptor_name":"Models, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D054884","descriptor_name":"Host-Pathogen Interactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D054884","descriptor_name":"Host-Pathogen Interactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D054884","descriptor_name":"Host-Pathogen Interactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D064307","descriptor_name":"Microbiota","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D064307","descriptor_name":"Microbiota","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D064307","descriptor_name":"Microbiota","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1109/tcbb.2019.2926716","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tcbb.2019.2926716","pdf_url":null,"source":{"id":"https://openalex.org/S36029991","display_name":"IEEE/ACM Transactions on Computational Biology and Bioinformatics","issn_l":"1545-5963","issn":["1545-5963","1557-9964","2374-0043"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE/ACM Transactions on Computational Biology and Bioinformatics","raw_type":"journal-article"},{"id":"pmid:31295117","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31295117","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE/ACM transactions on computational biology and bioinformatics","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Partnerships for the goals","id":"https://metadata.un.org/sdg/17","score":0.4399999976158142}],"awards":[{"id":"https://openalex.org/G3432038435","display_name":null,"funder_award_id":"61828205","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G358564744","display_name":null,"funder_award_id":"61420106009","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G7631435625","display_name":null,"funder_award_id":"B18059","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G8740223855","display_name":null,"funder_award_id":"61772552","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320310174","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305"},{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":68,"referenced_works":["https://openalex.org/W1553733317","https://openalex.org/W1970063271","https://openalex.org/W1971415551","https://openalex.org/W1975903901","https://openalex.org/W1984906148","https://openalex.org/W1991521547","https://openalex.org/W1996287810","https://openalex.org/W2002980923","https://openalex.org/W2004504447","https://openalex.org/W2012490955","https://openalex.org/W2023506796","https://openalex.org/W2024108088","https://openalex.org/W2028997113","https://openalex.org/W2030030445","https://openalex.org/W2035837169","https://openalex.org/W2041073071","https://openalex.org/W2041800481","https://openalex.org/W2044251889","https://openalex.org/W2057700969","https://openalex.org/W2058662072","https://openalex.org/W2070326624","https://openalex.org/W2080598921","https://openalex.org/W2084202098","https://openalex.org/W2089423792","https://openalex.org/W2095389688","https://openalex.org/W2097885651","https://openalex.org/W2098735230","https://openalex.org/W2103972604","https://openalex.org/W2106029302","https://openalex.org/W2108344016","https://openalex.org/W2112890441","https://openalex.org/W2116291006","https://openalex.org/W2120330409","https://openalex.org/W2125118217","https://openalex.org/W2128769815","https://openalex.org/W2131186249","https://openalex.org/W2131415145","https://openalex.org/W2144086069","https://openalex.org/W2145336165","https://openalex.org/W2151186216","https://openalex.org/W2165612380","https://openalex.org/W2169733549","https://openalex.org/W2212220212","https://openalex.org/W2256712352","https://openalex.org/W2322763599","https://openalex.org/W2463737032","https://openalex.org/W2531500048","https://openalex.org/W2567465856","https://openalex.org/W2584926544","https://openalex.org/W2590194234","https://openalex.org/W2597800471","https://openalex.org/W2608058823","https://openalex.org/W2739664659","https://openalex.org/W2748593099","https://openalex.org/W2751128104","https://openalex.org/W2752131265","https://openalex.org/W2765928324","https://openalex.org/W2771019114","https://openalex.org/W2772005301","https://openalex.org/W2790385355","https://openalex.org/W2797302609","https://openalex.org/W2801501532","https://openalex.org/W2810953629","https://openalex.org/W2906953716","https://openalex.org/W2922817064","https://openalex.org/W6630220111","https://openalex.org/W6737044836","https://openalex.org/W6760417521"],"related_works":["https://openalex.org/W1994775821","https://openalex.org/W2012019886","https://openalex.org/W2091133150","https://openalex.org/W2945869148","https://openalex.org/W2398781203","https://openalex.org/W2009279505","https://openalex.org/W4206503171","https://openalex.org/W4366711670","https://openalex.org/W2558988915","https://openalex.org/W2972216353"],"abstract_inverted_index":{"With":[0],"the":[1,30,65,109,117,124,139,162,183,191,210,230,244,252,266,270,279,295],"development":[2],"of":[3,47,83,127,141,186,213,241,255,282],"high-through":[4],"sequencing":[5],"technology":[6],"and":[7,25,34,85,87,148,169,203,215,224,257,261],"microbiology,":[8],"many":[9],"studies":[10,293],"have":[11],"evidenced":[12],"that":[13,234],"microbes":[14,33,84,129],"are":[15,265],"associated":[16],"with":[17],"human":[18,131],"diseases,":[19],"such":[20],"as":[21],"obesity,":[22],"liver":[23],"cancer,":[24],"so":[26],"on.":[27],"Therefore,":[28],"identifying":[29],"association":[31,49,158,172,184],"between":[32],"diseases":[35,86],"has":[36,51],"become":[37],"an":[38,53,285],"important":[39],"study":[40],"topic":[41],"in":[42,130,239,259,298],"current":[43],"bioinformatics.":[44],"The":[45,95,133],"emergence":[46],"microbe-disease":[48,62,78,89,111,157,171,188,287],"database":[50],"provided":[52],"unprecedented":[54],"opportunity":[55],"to":[56,76,181],"develop":[57],"computational":[58],"method":[59,73,178],"for":[60],"predicting":[61],"associations.":[63,112],"In":[64,273],"study,":[66],"we":[67,114,153,208,275],"propose":[68],"a":[69,92,155,175],"low-rank":[70],"matrix":[71,176],"completion":[72,177],"(called":[74],"MCHMDA)":[75],"predict":[77],"associations":[79,90,288],"by":[80,120,138,160,190],"integrating":[81,161],"similarities":[82],"known":[88,110,170],"into":[91,122],"heterogeneous":[93,156],"network.":[94,173],"microbe":[96,118,163],"similarity":[97,106,119,135,164,167],"is":[98,136,179],"computed":[99,137],"from":[100],"Gaussian":[101],"Interaction":[102],"Profile":[103],"(GIP)":[104],"kernel":[105],"based":[107],"on":[108,284],"Then,":[113,152],"further":[115,277],"improve":[116],"taking":[121],"account":[123],"inhabiting":[125],"organs":[126],"these":[128],"body.":[132],"disease":[134,142,145,149,166],"average":[140],"GIP":[143],"similarity,":[144,147],"symptom-based":[146],"functional":[150],"similarity.":[151],"construct":[154],"network":[159],"network,":[165,168],"Finally,":[174,291],"used":[180],"calculate":[182],"scores":[185],"unknown":[187],"pairs":[189],"fast":[192],"Singular":[193],"Value":[194],"Thresholding":[195],"(SVT)":[196],"algorithm.":[197],"Via":[198],"5-fold":[199],"Cross":[200,205],"Validation":[201,206],"(5CV)":[202],"Leave-One-Out":[204],"(LOOCV),":[207],"evaluate":[209],"prediction":[211,280,296],"performances":[212],"MCHMDA":[214,235,250,283],"other":[216,237],"state-of-the-art":[217],"methods":[218,238],"which":[219,264],"include":[220],"BRWMDA,":[221],"NGRHMDA,":[222],"LRLSHMDA,":[223],"KATZHMDA.":[225],"On":[226],"benchmark":[227],"dataset":[228,289],"HMDAD,":[229],"experimental":[231],"results":[232],"show":[233],"outperforms":[236],"terms":[240],"area":[242],"under":[243],"receiver":[245],"operating":[246],"characteristic":[247],"curve":[248],"(AUC).":[249],"achieves":[251],"AUC":[253],"values":[254,268],"0.9251":[256],"0.9495":[258],"5CV":[260],"LOOCV,":[262],"respectively,":[263],"highest":[267],"among":[269],"competing":[271],"methods.":[272],"addition,":[274],"also":[276],"indicate":[278],"generality":[281],"expanded":[286],"(HMDAD-SUP).":[290],"case":[292],"prove":[294],"ability":[297],"practical":[299],"applications.":[300]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":7},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":4},{"year":2017,"cited_by_count":1}],"updated_date":"2026-07-16T13:24:37.021932","created_date":"2025-10-10T00:00:00"}