{"id":"https://openalex.org/W2950884066","doi":"https://doi.org/10.1109/tcbb.2019.2923396","title":"Predicting the Antigenic Relationship of Foot-and-Mouth Disease Virus for Vaccine Selection Through a Computational Model","display_name":"Predicting the Antigenic Relationship of Foot-and-Mouth Disease Virus for Vaccine Selection Through a Computational Model","publication_year":2019,"publication_date":"2019-06-17","ids":{"openalex":"https://openalex.org/W2950884066","doi":"https://doi.org/10.1109/tcbb.2019.2923396","mag":"2950884066","pmid":"https://pubmed.ncbi.nlm.nih.gov/31217127"},"language":"en","primary_location":{"id":"doi:10.1109/tcbb.2019.2923396","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tcbb.2019.2923396","pdf_url":null,"source":{"id":"https://openalex.org/S36029991","display_name":"IEEE/ACM Transactions on Computational Biology and Bioinformatics","issn_l":"1545-5963","issn":["1545-5963","1557-9964","2374-0043"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE/ACM Transactions on Computational Biology and Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5061840111","display_name":"Jingxuan Qiu","orcid":"https://orcid.org/0000-0001-8420-4593"},"institutions":[{"id":"https://openalex.org/I148128674","display_name":"University of Shanghai for Science and Technology","ror":"https://ror.org/00ay9v204","country_code":"CN","type":"education","lineage":["https://openalex.org/I148128674"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Jingxuan Qiu","raw_affiliation_strings":["School of Medical Instrument and Food Engineering, University of Shanghai for Science and Technology, Shanghai, China"],"raw_orcid":"https://orcid.org/0000-0001-8420-4593","affiliations":[{"raw_affiliation_string":"School of Medical Instrument and Food Engineering, University of Shanghai for Science and Technology, Shanghai, China","institution_ids":["https://openalex.org/I148128674"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029170473","display_name":"Tianyi Qiu","orcid":"https://orcid.org/0000-0003-2619-0298"},"institutions":[{"id":"https://openalex.org/I4210106542","display_name":"Shanghai Public Health Clinical Center","ror":"https://ror.org/01nnwyz44","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210106542"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Tianyi Qiu","raw_affiliation_strings":["Shanghai Public Health Clinical Center & Institutes of Biomedical Sciences, Shanghai Medical School, Fudan University, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shanghai Public Health Clinical Center & Institutes of Biomedical Sciences, Shanghai Medical School, Fudan University, Shanghai, China","institution_ids":["https://openalex.org/I4210106542"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040110484","display_name":"Qingli Dong","orcid":"https://orcid.org/0000-0001-9019-0001"},"institutions":[{"id":"https://openalex.org/I148128674","display_name":"University of Shanghai for Science and Technology","ror":"https://ror.org/00ay9v204","country_code":"CN","type":"education","lineage":["https://openalex.org/I148128674"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qingli Dong","raw_affiliation_strings":["School of Medical Instrument and Food Engineering, University of Shanghai for Science and Technology, Shanghai, China"],"raw_orcid":"https://orcid.org/0000-0001-9019-0001","affiliations":[{"raw_affiliation_string":"School of Medical Instrument and Food Engineering, University of Shanghai for Science and Technology, Shanghai, China","institution_ids":["https://openalex.org/I148128674"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006931854","display_name":"Dongpo Xu","orcid":"https://orcid.org/0000-0002-9311-9152"},"institutions":[{"id":"https://openalex.org/I148128674","display_name":"University of Shanghai for Science and Technology","ror":"https://ror.org/00ay9v204","country_code":"CN","type":"education","lineage":["https://openalex.org/I148128674"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Dongpo Xu","raw_affiliation_strings":["School of Medical Instrument and Food Engineering, University of Shanghai for Science and Technology, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Medical Instrument and Food Engineering, University of Shanghai for Science and Technology, Shanghai, China","institution_ids":["https://openalex.org/I148128674"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100389011","display_name":"Xiang Wang","orcid":"https://orcid.org/0000-0002-1935-4787"},"institutions":[{"id":"https://openalex.org/I148128674","display_name":"University of Shanghai for Science and Technology","ror":"https://ror.org/00ay9v204","country_code":"CN","type":"education","lineage":["https://openalex.org/I148128674"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiang Wang","raw_affiliation_strings":["School of Medical Instrument and Food Engineering, University of Shanghai for Science and Technology, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Medical Instrument and Food Engineering, University of Shanghai for Science and Technology, Shanghai, China","institution_ids":["https://openalex.org/I148128674"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012120539","display_name":"Qi Zhang","orcid":"https://orcid.org/0000-0002-9021-3960"},"institutions":[{"id":"https://openalex.org/I148128674","display_name":"University of Shanghai for Science and Technology","ror":"https://ror.org/00ay9v204","country_code":"CN","type":"education","lineage":["https://openalex.org/I148128674"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qi Zhang","raw_affiliation_strings":["School of Medical Instrument and Food Engineering, University of Shanghai for Science and Technology, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Medical Instrument and Food Engineering, University of Shanghai for Science and Technology, Shanghai, China","institution_ids":["https://openalex.org/I148128674"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075989197","display_name":"Jing Pan","orcid":"https://orcid.org/0000-0001-6081-3204"},"institutions":[{"id":"https://openalex.org/I148128674","display_name":"University of Shanghai for Science and Technology","ror":"https://ror.org/00ay9v204","country_code":"CN","type":"education","lineage":["https://openalex.org/I148128674"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jing Pan","raw_affiliation_strings":["School of Medical Instrument and Food Engineering, University of Shanghai for Science and Technology, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Medical Instrument and Food Engineering, University of Shanghai for Science and Technology, Shanghai, China","institution_ids":["https://openalex.org/I148128674"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5036519664","display_name":"Qing Liu","orcid":"https://orcid.org/0000-0002-6163-2488"},"institutions":[{"id":"https://openalex.org/I148128674","display_name":"University of Shanghai for Science and Technology","ror":"https://ror.org/00ay9v204","country_code":"CN","type":"education","lineage":["https://openalex.org/I148128674"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qing Liu","raw_affiliation_strings":["School of Medical Instrument and Food Engineering, University of Shanghai for Science and Technology, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Medical Instrument and Food Engineering, University of Shanghai for Science and Technology, Shanghai, China","institution_ids":["https://openalex.org/I148128674"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5061840111"],"corresponding_institution_ids":["https://openalex.org/I148128674"],"apc_list":null,"apc_paid":null,"fwci":0.2816,"has_fulltext":false,"cited_by_count":10,"citation_normalized_percentile":{"value":0.57911153,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"18","issue":"2","first_page":"677","last_page":"685"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11560","display_name":"Animal Disease Management and Epidemiology","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1102","display_name":"Agronomy and Crop Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11560","display_name":"Animal Disease Management and Epidemiology","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1102","display_name":"Agronomy and Crop Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11112","display_name":"Viral Infections and Immunology Research","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12733","display_name":"Vector-Borne Animal Diseases","score":0.9937000274658203,"subfield":{"id":"https://openalex.org/subfields/1105","display_name":"Ecology, Evolution, Behavior and Systematics"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/antigenicity","display_name":"Antigenicity","score":0.9881970286369324},{"id":"https://openalex.org/keywords/virology","display_name":"Virology","score":0.6681910753250122},{"id":"https://openalex.org/keywords/foot-and-mouth-disease-virus","display_name":"Foot-and-mouth disease virus","score":0.6258664727210999},{"id":"https://openalex.org/keywords/antigen","display_name":"Antigen","score":0.5971826314926147},{"id":"https://openalex.org/keywords/foot-and-mouth-disease","display_name":"Foot-and-mouth disease","score":0.472636878490448},{"id":"https://openalex.org/keywords/virus","display_name":"Virus","score":0.4600967764854431},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.44961658120155334},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.3543342351913452},{"id":"https://openalex.org/keywords/immunology","display_name":"Immunology","score":0.2518503665924072}],"concepts":[{"id":"https://openalex.org/C2779026604","wikidata":"https://www.wikidata.org/wiki/Q4774742","display_name":"Antigenicity","level":3,"score":0.9881970286369324},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.6681910753250122},{"id":"https://openalex.org/C2776151397","wikidata":"https://www.wikidata.org/wiki/Q1911079","display_name":"Foot-and-mouth disease virus","level":3,"score":0.6258664727210999},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.5971826314926147},{"id":"https://openalex.org/C2779070877","wikidata":"https://www.wikidata.org/wiki/Q152401","display_name":"Foot-and-mouth disease","level":3,"score":0.472636878490448},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.4600967764854431},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.44961658120155334},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3543342351913452},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.2518503665924072}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000956","descriptor_name":"Antigens, Viral","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D000956","descriptor_name":"Antigens, Viral","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D000956","descriptor_name":"Antigens, Viral","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D000956","descriptor_name":"Antigens, Viral","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D000956","descriptor_name":"Antigens, Viral","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D000956","descriptor_name":"Antigens, Viral","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D000956","descriptor_name":"Antigens, Viral","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D000956","descriptor_name":"Antigens, Viral","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D000956","descriptor_name":"Antigens, Viral","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D005536","descriptor_name":"Foot-and-Mouth Disease","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D005536","descriptor_name":"Foot-and-Mouth Disease","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D005536","descriptor_name":"Foot-and-Mouth Disease","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D005536","descriptor_name":"Foot-and-Mouth Disease","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D005536","descriptor_name":"Foot-and-Mouth Disease","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D005536","descriptor_name":"Foot-and-Mouth Disease","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D005536","descriptor_name":"Foot-and-Mouth Disease","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":true},{"descriptor_ui":"D005536","descriptor_name":"Foot-and-Mouth Disease","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":true},{"descriptor_ui":"D005536","descriptor_name":"Foot-and-Mouth Disease","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":true},{"descriptor_ui":"D014765","descriptor_name":"Viral Vaccines","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014765","descriptor_name":"Viral Vaccines","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014765","descriptor_name":"Viral Vaccines","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018448","descriptor_name":"Models, Immunological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018448","descriptor_name":"Models, Immunological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018448","descriptor_name":"Models, Immunological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D029544","descriptor_name":"Foot-and-Mouth Disease Virus","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D029544","descriptor_name":"Foot-and-Mouth Disease Virus","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D029544","descriptor_name":"Foot-and-Mouth Disease Virus","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D029544","descriptor_name":"Foot-and-Mouth Disease Virus","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D029544","descriptor_name":"Foot-and-Mouth Disease Virus","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D029544","descriptor_name":"Foot-and-Mouth Disease Virus","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D029544","descriptor_name":"Foot-and-Mouth Disease Virus","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D029544","descriptor_name":"Foot-and-Mouth Disease Virus","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D029544","descriptor_name":"Foot-and-Mouth Disease Virus","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1109/tcbb.2019.2923396","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tcbb.2019.2923396","pdf_url":null,"source":{"id":"https://openalex.org/S36029991","display_name":"IEEE/ACM Transactions on Computational Biology and Bioinformatics","issn_l":"1545-5963","issn":["1545-5963","1557-9964","2374-0043"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE/ACM Transactions on Computational Biology and Bioinformatics","raw_type":"journal-article"},{"id":"pmid:31217127","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31217127","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE/ACM transactions on computational biology and bioinformatics","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8399999737739563,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"awards":[{"id":"https://openalex.org/G1387878532","display_name":null,"funder_award_id":"81572809","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G2074646960","display_name":null,"funder_award_id":"31871897","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G3295512625","display_name":null,"funder_award_id":"2018M640410","funder_id":"https://openalex.org/F4320321543","funder_display_name":"China Postdoctoral Science Foundation"},{"id":"https://openalex.org/G5578389782","display_name":null,"funder_award_id":"31801455","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320321543","display_name":"China Postdoctoral Science Foundation","ror":"https://ror.org/0426zh255"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":28,"referenced_works":["https://openalex.org/W87967796","https://openalex.org/W1673726422","https://openalex.org/W1846491462","https://openalex.org/W1967129091","https://openalex.org/W1988724578","https://openalex.org/W1998954852","https://openalex.org/W2000320681","https://openalex.org/W2012332927","https://openalex.org/W2014731953","https://openalex.org/W2041740757","https://openalex.org/W2044162698","https://openalex.org/W2048976731","https://openalex.org/W2057839080","https://openalex.org/W2070045122","https://openalex.org/W2074054216","https://openalex.org/W2098480775","https://openalex.org/W2102480829","https://openalex.org/W2142656395","https://openalex.org/W2145605402","https://openalex.org/W2146714484","https://openalex.org/W2150705458","https://openalex.org/W2158714788","https://openalex.org/W2168795142","https://openalex.org/W2302905190","https://openalex.org/W2766737008","https://openalex.org/W2802551462","https://openalex.org/W2804822363","https://openalex.org/W4213345021"],"related_works":["https://openalex.org/W4236348038","https://openalex.org/W1983326968","https://openalex.org/W2008200664","https://openalex.org/W2406539109","https://openalex.org/W2425724560","https://openalex.org/W2914017467","https://openalex.org/W1569506334","https://openalex.org/W2053035650","https://openalex.org/W1968953691","https://openalex.org/W2089023830"],"abstract_inverted_index":{"Foot-and-mouth":[0],"disease":[1,17],"virus":[2,8],"(FMDV)":[3],"is":[4,10],"an":[5,57,100],"antigenic-variable":[6],"RNA":[7],"that":[9,170],"responsible":[11],"for":[12,181,194],"the":[13,48,64,74,106,110,141,171,182],"recurrence":[14],"of":[15,50,66,97,103,109,125,143,186],"foot-and-mouth":[16],"in":[18,112,175,191],"livestock":[19],"and":[20,24,41,81,99,163,188],"can":[21],"be":[22,179],"prevented":[23],"controlled":[25],"using":[26],"a":[27,77,94],"vaccine":[28,128,165,192],"with":[29],"broad-spectrum":[30,151],"protection.":[31],"Current":[32],"anti-genicity":[33],"evaluation":[34],"methods,":[35],"which":[36],"involve":[37],"animal":[38],"immunity":[39],"experiments":[40],"serum":[42],"preparation,":[43],"are":[44],"unable":[45],"to":[46,61,87,119,148,158],"fulfill":[47],"needs":[49],"high-throughput":[51,183],"antigenicity":[52,58,65,89,113,123,184],"measurements.":[53],"This":[54],"study":[55,177],"designed":[56,174],"scoring":[59,79],"model":[60,111,118,145,173],"rapidly":[62],"predict":[63],"FMDV.":[67],"Antigenic-dominant":[68],"sites":[69],"were":[70,85],"initially":[71],"determined":[72],"on":[73],"VP1":[75],"protein,":[76],"position-specific":[78],"matrix":[80],"physical":[82],"chemical":[83],"indexes":[84],"integrated":[86],"generate":[88],"descriptors.":[90],"Independent":[91],"tests":[92],"showed":[93],"high":[95],"accuracy":[96],"0.848":[98],"AUC":[101],"value":[102],"0.889,":[104],"indicating":[105],"good":[107],"performance":[108],"measurement.":[114],"When":[115],"applying":[116],"this":[117,133,144,176],"historical":[120,155],"data,":[121],"annual":[122],"coverage":[124],"widely":[126],"used":[127,180],"strains":[129,157],"was":[130,134,146],"successfully":[131],"evaluated,":[132],"also":[135],"supported":[136],"by":[137],"previous":[138],"experiments.":[139],"Furthermore,":[140],"utility":[142],"extended":[147],"select":[149],"potential":[150,160],"vaccines":[152],"among":[153],"1,201":[154],"non-redundant":[156],"recommend":[159],"univalent,":[161],"bivalent":[162],"trivalent":[164],"candidates.":[166],"The":[167],"results":[168],"suggested":[169],"computational":[172],"could":[178,189],"measurement":[185],"FMDV":[187,196],"aid":[190],"development":[193],"preventing":[195],"epidemics.":[197]},"counts_by_year":[{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":2},{"year":2021,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}