{"id":"https://openalex.org/W2897658119","doi":"https://doi.org/10.1109/tcbb.2018.2876527","title":"SVSR: A Program to Simulate Structural Variations and Generate Sequencing Reads for Multiple Platforms","display_name":"SVSR: A Program to Simulate Structural Variations and Generate Sequencing Reads for Multiple Platforms","publication_year":2018,"publication_date":"2018-10-17","ids":{"openalex":"https://openalex.org/W2897658119","doi":"https://doi.org/10.1109/tcbb.2018.2876527","mag":"2897658119","pmid":"https://pubmed.ncbi.nlm.nih.gov/30334804"},"language":"en","primary_location":{"id":"doi:10.1109/tcbb.2018.2876527","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tcbb.2018.2876527","pdf_url":null,"source":{"id":"https://openalex.org/S36029991","display_name":"IEEE/ACM Transactions on Computational Biology and Bioinformatics","issn_l":"1545-5963","issn":["1545-5963","1557-9964","2374-0043","2998-4165"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE/ACM Transactions on Computational Biology and Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5017698164","display_name":"Xiguo Yuan","orcid":"https://orcid.org/0000-0002-0822-5189"},"institutions":[{"id":"https://openalex.org/I149594827","display_name":"Xidian University","ror":"https://ror.org/05s92vm98","country_code":"CN","type":"education","lineage":["https://openalex.org/I149594827"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiguo Yuan","raw_affiliation_strings":["School of Computer Science and Technology, Xidian University, Xi'an, China"],"raw_orcid":"https://orcid.org/0000-0002-0822-5189","affiliations":[{"raw_affiliation_string":"School of Computer Science and Technology, Xidian University, Xi'an, China","institution_ids":["https://openalex.org/I149594827"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041895155","display_name":"Meihong Gao","orcid":"https://orcid.org/0000-0002-9935-7979"},"institutions":[{"id":"https://openalex.org/I149594827","display_name":"Xidian University","ror":"https://ror.org/05s92vm98","country_code":"CN","type":"education","lineage":["https://openalex.org/I149594827"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Meihong Gao","raw_affiliation_strings":["School of Computer Science and Technology, Xidian University, Xi'an, China"],"raw_orcid":"https://orcid.org/0000-0002-9935-7979","affiliations":[{"raw_affiliation_string":"School of Computer Science and Technology, Xidian University, Xi'an, China","institution_ids":["https://openalex.org/I149594827"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056070962","display_name":"Jun Bai","orcid":"https://orcid.org/0000-0003-4589-6560"},"institutions":[{"id":"https://openalex.org/I17721919","display_name":"Shanxi Medical University","ror":"https://ror.org/0265d1010","country_code":"CN","type":"education","lineage":["https://openalex.org/I17721919"]},{"id":"https://openalex.org/I4210160763","display_name":"Shanxi Provincial People\u2019s Hospital","ror":"https://ror.org/057ckzt47","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I17721919","https://openalex.org/I4210160763"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jun Bai","raw_affiliation_strings":["Department of Medical Oncology, Shaanxi Provincial People's Hospital, Xi'an, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Oncology, Shaanxi Provincial People's Hospital, Xi'an, China","institution_ids":["https://openalex.org/I17721919","https://openalex.org/I4210160763"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5023726254","display_name":"Junbo Duan","orcid":"https://orcid.org/0000-0001-7170-3772"},"institutions":[{"id":"https://openalex.org/I87445476","display_name":"Xi'an Jiaotong University","ror":"https://ror.org/017zhmm22","country_code":"CN","type":"education","lineage":["https://openalex.org/I87445476"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Junbo Duan","raw_affiliation_strings":["Key Laboratory of Biomedical Information Engineering of Ministry of Education, Department of Biomedical Engineering, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, China"],"raw_orcid":"https://orcid.org/0000-0001-7170-3772","affiliations":[{"raw_affiliation_string":"Key Laboratory of Biomedical Information Engineering of Ministry of Education, Department of Biomedical Engineering, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, China","institution_ids":["https://openalex.org/I87445476"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.7418,"has_fulltext":false,"cited_by_count":13,"citation_normalized_percentile":{"value":0.69551839,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":97},"biblio":{"volume":"17","issue":"3","first_page":"1082","last_page":"1091"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11213","display_name":"Genomic variations and chromosomal abnormalities","score":0.9980999827384949,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11287","display_name":"Cancer Genomics and Diagnostics","score":0.996399998664856,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/indel","display_name":"Indel","score":0.8293067216873169},{"id":"https://openalex.org/keywords/structural-variation","display_name":"Structural variation","score":0.7964987754821777},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5884434580802917},{"id":"https://openalex.org/keywords/copy-number-variation","display_name":"Copy-number variation","score":0.5451812148094177},{"id":"https://openalex.org/keywords/genome","display_name":"Genome","score":0.5434151291847229},{"id":"https://openalex.org/keywords/human-genome","display_name":"Human genome","score":0.5397039651870728},{"id":"https://openalex.org/keywords/dna-sequencing","display_name":"DNA sequencing","score":0.4812443256378174},{"id":"https://openalex.org/keywords/probabilistic-logic","display_name":"Probabilistic logic","score":0.4753263294696808},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.4737055003643036},{"id":"https://openalex.org/keywords/benchmarking","display_name":"Benchmarking","score":0.4730873703956604},{"id":"https://openalex.org/keywords/selection","display_name":"Selection (genetic algorithm)","score":0.4260951280593872},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.38483020663261414},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.2763398587703705},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.26237165927886963},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.22259879112243652},{"id":"https://openalex.org/keywords/single-nucleotide-polymorphism","display_name":"Single-nucleotide polymorphism","score":0.19146952033042908},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.1336798369884491}],"concepts":[{"id":"https://openalex.org/C119054055","wikidata":"https://www.wikidata.org/wiki/Q1576681","display_name":"Indel","level":5,"score":0.8293067216873169},{"id":"https://openalex.org/C151020129","wikidata":"https://www.wikidata.org/wiki/Q7625067","display_name":"Structural variation","level":4,"score":0.7964987754821777},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5884434580802917},{"id":"https://openalex.org/C120821319","wikidata":"https://www.wikidata.org/wiki/Q1501491","display_name":"Copy-number variation","level":4,"score":0.5451812148094177},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.5434151291847229},{"id":"https://openalex.org/C197077220","wikidata":"https://www.wikidata.org/wiki/Q720988","display_name":"Human genome","level":4,"score":0.5397039651870728},{"id":"https://openalex.org/C51679486","wikidata":"https://www.wikidata.org/wiki/Q380546","display_name":"DNA sequencing","level":3,"score":0.4812443256378174},{"id":"https://openalex.org/C49937458","wikidata":"https://www.wikidata.org/wiki/Q2599292","display_name":"Probabilistic logic","level":2,"score":0.4753263294696808},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4737055003643036},{"id":"https://openalex.org/C86251818","wikidata":"https://www.wikidata.org/wiki/Q816754","display_name":"Benchmarking","level":2,"score":0.4730873703956604},{"id":"https://openalex.org/C81917197","wikidata":"https://www.wikidata.org/wiki/Q628760","display_name":"Selection (genetic algorithm)","level":2,"score":0.4260951280593872},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.38483020663261414},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2763398587703705},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.26237165927886963},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.22259879112243652},{"id":"https://openalex.org/C153209595","wikidata":"https://www.wikidata.org/wiki/Q501128","display_name":"Single-nucleotide polymorphism","level":4,"score":0.19146952033042908},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.1336798369884491},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.0},{"id":"https://openalex.org/C144133560","wikidata":"https://www.wikidata.org/wiki/Q4830453","display_name":"Business","level":0,"score":0.0},{"id":"https://openalex.org/C162853370","wikidata":"https://www.wikidata.org/wiki/Q39809","display_name":"Marketing","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015894","descriptor_name":"Genome, Human","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015894","descriptor_name":"Genome, Human","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015894","descriptor_name":"Genome, Human","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017422","descriptor_name":"Sequence Analysis, DNA","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D017422","descriptor_name":"Sequence Analysis, DNA","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D017422","descriptor_name":"Sequence Analysis, DNA","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020641","descriptor_name":"Polymorphism, Single Nucleotide","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D020641","descriptor_name":"Polymorphism, Single Nucleotide","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D020641","descriptor_name":"Polymorphism, Single Nucleotide","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D054643","descriptor_name":"INDEL Mutation","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D054643","descriptor_name":"INDEL Mutation","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D054643","descriptor_name":"INDEL Mutation","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D056914","descriptor_name":"Genomic Structural Variation","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D056914","descriptor_name":"Genomic Structural Variation","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D056914","descriptor_name":"Genomic Structural Variation","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D059014","descriptor_name":"High-Throughput Nucleotide Sequencing","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D059014","descriptor_name":"High-Throughput Nucleotide Sequencing","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D059014","descriptor_name":"High-Throughput Nucleotide Sequencing","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1109/tcbb.2018.2876527","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tcbb.2018.2876527","pdf_url":null,"source":{"id":"https://openalex.org/S36029991","display_name":"IEEE/ACM Transactions on Computational Biology and Bioinformatics","issn_l":"1545-5963","issn":["1545-5963","1557-9964","2374-0043","2998-4165"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE/ACM Transactions on Computational Biology and Bioinformatics","raw_type":"journal-article"},{"id":"pmid:30334804","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30334804","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE/ACM transactions on computational biology and bioinformatics","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G7371832276","display_name":null,"funder_award_id":"JBZ170301","funder_id":"https://openalex.org/F4320335787","funder_display_name":"Fundamental Research Funds for the Central Universities"},{"id":"https://openalex.org/G7623042354","display_name":"\u57fa\u4e8e\u65b0\u4e00\u4ee3\u6d4b\u5e8f\u6570\u636e\u7684\u80bf\u7624\u7eaf\u5ea6\u53ca\u500d\u4f53\u52a8\u6001\u9884\u6d4b\u65b9\u6cd5\u7814\u7a76","funder_award_id":"61571341","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320335787","display_name":"Fundamental Research Funds for the Central Universities","ror":null}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":48,"referenced_works":["https://openalex.org/W1772725728","https://openalex.org/W1965023353","https://openalex.org/W1966938977","https://openalex.org/W1996921570","https://openalex.org/W1998120162","https://openalex.org/W1998330439","https://openalex.org/W2017535462","https://openalex.org/W2021716816","https://openalex.org/W2024789434","https://openalex.org/W2025261434","https://openalex.org/W2038840669","https://openalex.org/W2042272913","https://openalex.org/W2059565617","https://openalex.org/W2061008984","https://openalex.org/W2061449102","https://openalex.org/W2080468303","https://openalex.org/W2085755265","https://openalex.org/W2096148096","https://openalex.org/W2103962160","https://openalex.org/W2107038793","https://openalex.org/W2108234281","https://openalex.org/W2121743948","https://openalex.org/W2122769974","https://openalex.org/W2123444907","https://openalex.org/W2126948011","https://openalex.org/W2130996300","https://openalex.org/W2141978199","https://openalex.org/W2145629225","https://openalex.org/W2146472631","https://openalex.org/W2150264767","https://openalex.org/W2150506261","https://openalex.org/W2153631649","https://openalex.org/W2157539385","https://openalex.org/W2158460758","https://openalex.org/W2158529347","https://openalex.org/W2160515792","https://openalex.org/W2161266543","https://openalex.org/W2162212014","https://openalex.org/W2165765309","https://openalex.org/W2168133698","https://openalex.org/W2193989147","https://openalex.org/W2194510225","https://openalex.org/W2263137078","https://openalex.org/W2343469482","https://openalex.org/W2362469198","https://openalex.org/W2602272716","https://openalex.org/W2738842617","https://openalex.org/W2953359555"],"related_works":["https://openalex.org/W2160515792","https://openalex.org/W2156272823","https://openalex.org/W3134412476","https://openalex.org/W2842676186","https://openalex.org/W2160911017","https://openalex.org/W2005276393","https://openalex.org/W2091911799","https://openalex.org/W2365914065","https://openalex.org/W3166677598","https://openalex.org/W2026058428"],"abstract_inverted_index":{"Structural":[0],"variation":[1,189],"accounts":[2],"for":[3,50,78],"a":[4,31,58,100,118],"major":[5],"fraction":[6],"of":[7,27,39,66,117,128,187,196],"mutations":[8],"in":[9],"the":[10,24,52,79,114,122,185,194],"human":[11,80],"genome":[12,81,120],"and":[13,42,74,76,82,95,135,142,149,173,192],"confers":[14],"susceptibility":[15],"to":[16,34,62,83,107,121,131,139,153,183],"complex":[17],"diseases.":[18],"Next":[19],"generation":[20],"sequencing":[21,43,85],"along":[22],"with":[23,45,87,176],"rapid":[25],"development":[26,195],"computational":[28,53,198],"methods":[29,191],"provides":[30],"cost-effective":[32],"procedure":[33],"detect":[35],"such":[36],"variations.":[37],"Simulation":[38],"structural":[40,67,188],"variations":[41,68],"reads":[44,86],"real":[46,105],"characteristics":[47],"is":[48,181],"essential":[49],"benchmarking":[51],"methods.":[54,199],"Here,":[55],"we":[56,125,145],"develop":[57],"new":[59,197],"program,":[60],"SVSR,":[61],"simulate":[63],"five":[64],"types":[65],"(indels,":[69],"tandem":[70],"duplication,":[71],"CNVs,":[72],"inversions,":[73],"translocations)":[75],"SNPs":[77],"generate":[84,154,174],"features":[88,169],"from":[89,104,113],"popular":[90],"platforms":[91],"(Illumina,":[92],"SOLiD,":[93],"454,":[94],"Ion":[96],"Torrent).":[97],"We":[98],"adopt":[99],"selection":[101],"model":[102],"trained":[103],"data":[106],"predict":[108],"copy":[109],"number":[110],"states,":[111],"starting":[112],"first":[115],"site":[116],"particular":[119],"end.":[123],"Furthermore,":[124],"utilize":[126],"references":[127],"microbial":[129],"genomes":[130],"produce":[132],"insertion":[133],"fragments":[134],"design":[136],"probabilistic":[137],"models":[138],"imitate":[140],"inversions":[141],"translocations.":[143],"Moreover,":[144],"create":[146],"platform-specific":[147],"errors":[148],"base":[150],"quality":[151,178],"profiles":[152],"normal,":[155],"tumor,":[156],"or":[157],"normal-tumor":[158],"mixture":[159],"reads.":[160],"Experimental":[161],"results":[162],"show":[163],"that":[164,170],"SVSR":[165,180],"could":[166],"capture":[167],"more":[168],"are":[171],"realistic":[172],"datasets":[175],"satisfactory":[177],"scores.":[179],"able":[182],"evaluate":[184],"performance":[186],"detection":[190],"guide":[193]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":3},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":2}],"updated_date":"2026-07-28T07:46:37.118299","created_date":"2025-10-10T00:00:00"}