{"id":"https://openalex.org/W2896170599","doi":"https://doi.org/10.1109/tcbb.2018.2875684","title":"Automated Cell Tracking Using Motion Prediction-Based Matching and Event Handling","display_name":"Automated Cell Tracking Using Motion Prediction-Based Matching and Event Handling","publication_year":2018,"publication_date":"2018-10-12","ids":{"openalex":"https://openalex.org/W2896170599","doi":"https://doi.org/10.1109/tcbb.2018.2875684","mag":"2896170599","pmid":"https://pubmed.ncbi.nlm.nih.gov/30334766"},"language":"en","primary_location":{"id":"doi:10.1109/tcbb.2018.2875684","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tcbb.2018.2875684","pdf_url":null,"source":{"id":"https://openalex.org/S36029991","display_name":"IEEE/ACM Transactions on Computational Biology and Bioinformatics","issn_l":"1545-5963","issn":["1545-5963","1557-9964","2374-0043"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE/ACM Transactions on Computational Biology and Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6832744","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5043346818","display_name":"Fatima Boukari","orcid":"https://orcid.org/0000-0001-7155-7082"},"institutions":[{"id":"https://openalex.org/I126548940","display_name":"Delaware State University","ror":"https://ror.org/03g35dg18","country_code":"US","type":"education","lineage":["https://openalex.org/I126548940"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Fatima Boukari","raw_affiliation_strings":["Division of Physical and Computational Sciences, Delaware State University, Dover, USA"],"affiliations":[{"raw_affiliation_string":"Division of Physical and Computational Sciences, Delaware State University, Dover, USA","institution_ids":["https://openalex.org/I126548940"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5074243216","display_name":"Sokratis Makrogiannis","orcid":"https://orcid.org/0000-0003-0316-3529"},"institutions":[{"id":"https://openalex.org/I126548940","display_name":"Delaware State University","ror":"https://ror.org/03g35dg18","country_code":"US","type":"education","lineage":["https://openalex.org/I126548940"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sokratis Makrogiannis","raw_affiliation_strings":["Division of Physical and Computational Sciences, Delaware State University, Dover, USA"],"affiliations":[{"raw_affiliation_string":"Division of Physical and Computational Sciences, Delaware State University, Dover, USA","institution_ids":["https://openalex.org/I126548940"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5043346818"],"corresponding_institution_ids":["https://openalex.org/I126548940"],"apc_list":null,"apc_paid":null,"fwci":0.8947,"has_fulltext":false,"cited_by_count":24,"citation_normalized_percentile":{"value":0.72970497,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"17","issue":"3","first_page":"959","last_page":"971"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11829","display_name":"Mathematical Biology Tumor Growth","score":0.9940999746322632,"subfield":{"id":"https://openalex.org/subfields/2611","display_name":"Modeling and Simulation"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11829","display_name":"Mathematical Biology Tumor Growth","score":0.9940999746322632,"subfield":{"id":"https://openalex.org/subfields/2611","display_name":"Modeling and Simulation"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.9907000064849854,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11289","display_name":"Single-cell and spatial transcriptomics","score":0.9876999855041504,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.635675311088562},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.6287760734558105},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.617858350276947},{"id":"https://openalex.org/keywords/segmentation","display_name":"Segmentation","score":0.5894246697425842},{"id":"https://openalex.org/keywords/tracking","display_name":"Tracking (education)","score":0.5673837661743164},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.433957576751709}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.635675311088562},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.6287760734558105},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.617858350276947},{"id":"https://openalex.org/C89600930","wikidata":"https://www.wikidata.org/wiki/Q1423946","display_name":"Segmentation","level":2,"score":0.5894246697425842},{"id":"https://openalex.org/C2775936607","wikidata":"https://www.wikidata.org/wiki/Q466845","display_name":"Tracking (education)","level":2,"score":0.5673837661743164},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.433957576751709},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.0},{"id":"https://openalex.org/C19417346","wikidata":"https://www.wikidata.org/wiki/Q7922","display_name":"Pedagogy","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002465","descriptor_name":"Cell Movement","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D002465","descriptor_name":"Cell Movement","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D002465","descriptor_name":"Cell Movement","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D002465","descriptor_name":"Cell Movement","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006367","descriptor_name":"HeLa Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006367","descriptor_name":"HeLa Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006367","descriptor_name":"HeLa Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006367","descriptor_name":"HeLa Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D021621","descriptor_name":"Imaging, Three-Dimensional","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D021621","descriptor_name":"Imaging, Three-Dimensional","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D021621","descriptor_name":"Imaging, Three-Dimensional","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D021621","descriptor_name":"Imaging, Three-Dimensional","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D058948","descriptor_name":"Cell Tracking","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D058948","descriptor_name":"Cell Tracking","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D058948","descriptor_name":"Cell Tracking","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D058948","descriptor_name":"Cell Tracking","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D059010","descriptor_name":"Single-Cell Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059010","descriptor_name":"Single-Cell Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059010","descriptor_name":"Single-Cell Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059010","descriptor_name":"Single-Cell Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1109/tcbb.2018.2875684","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tcbb.2018.2875684","pdf_url":null,"source":{"id":"https://openalex.org/S36029991","display_name":"IEEE/ACM Transactions on Computational Biology and Bioinformatics","issn_l":"1545-5963","issn":["1545-5963","1557-9964","2374-0043"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE/ACM Transactions on Computational Biology and Bioinformatics","raw_type":"journal-article"},{"id":"pmid:30334766","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30334766","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE/ACM transactions on computational biology and bioinformatics","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:6832744","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6832744","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"IEEE/ACM Trans Comput Biol Bioinform","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:6832744","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6832744","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"IEEE/ACM Trans Comput Biol Bioinform","raw_type":"Text"},"sustainable_development_goals":[{"score":0.6200000047683716,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320307773","display_name":"GlaxoSmithKline","ror":"https://ror.org/01xsqw823"},{"id":"https://openalex.org/F4320308928","display_name":"University of Delaware","ror":"https://ror.org/01sbq1a82"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"},{"id":"https://openalex.org/F4320338075","display_name":"Core Research for Evolutional Science and Technology","ror":"https://ror.org/00097mb19"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":51,"referenced_works":["https://openalex.org/W13520748","https://openalex.org/W144339231","https://openalex.org/W250969727","https://openalex.org/W1490760466","https://openalex.org/W1561442812","https://openalex.org/W1578285471","https://openalex.org/W1867429401","https://openalex.org/W1901129140","https://openalex.org/W1931278930","https://openalex.org/W1973421894","https://openalex.org/W1978372216","https://openalex.org/W2002089932","https://openalex.org/W2004369799","https://openalex.org/W2004481819","https://openalex.org/W2011604289","https://openalex.org/W2026448092","https://openalex.org/W2040516748","https://openalex.org/W2044502771","https://openalex.org/W2044599041","https://openalex.org/W2063886817","https://openalex.org/W2066130773","https://openalex.org/W2111202632","https://openalex.org/W2118877769","https://openalex.org/W2119049509","https://openalex.org/W2119774436","https://openalex.org/W2122502232","https://openalex.org/W2129223507","https://openalex.org/W2132355119","https://openalex.org/W2135853930","https://openalex.org/W2136893947","https://openalex.org/W2141273399","https://openalex.org/W2151538727","https://openalex.org/W2154504070","https://openalex.org/W2155296963","https://openalex.org/W2158052446","https://openalex.org/W2158672167","https://openalex.org/W2159960204","https://openalex.org/W2162245111","https://openalex.org/W2201862160","https://openalex.org/W2294930922","https://openalex.org/W2320839648","https://openalex.org/W2344654247","https://openalex.org/W2492154801","https://openalex.org/W2514273899","https://openalex.org/W2536325021","https://openalex.org/W2592929672","https://openalex.org/W2751023760","https://openalex.org/W2758694956","https://openalex.org/W2768673271","https://openalex.org/W4249022109","https://openalex.org/W6729036164"],"related_works":["https://openalex.org/W2058170566","https://openalex.org/W2755342338","https://openalex.org/W2772917594","https://openalex.org/W2775347418","https://openalex.org/W2166024367","https://openalex.org/W3116076068","https://openalex.org/W2229312674","https://openalex.org/W2951359407","https://openalex.org/W2079911747","https://openalex.org/W1969923398"],"abstract_inverted_index":{"Automated":[0],"cell":[1,12,35,87,92,103,110,113,139,144,150,153,165],"segmentation":[2,179,196],"and":[3,10,14,23,39,112,152,160,163,192,197],"tracking":[4,66,111,166,174,184,198],"enables":[5],"the":[6,46,65,79,85,135,149,193],"quantification":[7],"of":[8,128,137,189,204],"static":[9],"dynamic":[11],"characteristics":[13],"is":[15,43],"significant":[16],"for":[17,32],"disease":[18],"diagnosis,":[19],"treatment,":[20],"drug":[21],"development,":[22],"other":[24],"biomedical":[25],"applications.":[26],"This":[27],"paper":[28],"introduces":[29],"a":[30,51,70,96,117,123,129,143],"method":[31,175],"fully":[33,194],"automated":[34,173,195],"tracking,":[36],"lineage":[37,145],"construction,":[38],"quantification.":[40],"Cell":[41],"detection":[42,115],"performed":[44],"in":[45],"joint":[47,72],"spatio-temporal":[48],"domain":[49],"by":[50,126],"motion":[52,80,88],"diffusion-based":[53],"Partial":[54],"Differential":[55],"Equation":[56],"(PDE)":[57],"combined":[58],"with":[59,90],"energy":[60],"minimizing":[61],"active":[62],"contours.":[63],"In":[64],"stage,":[67],"we":[68,156],"adopt":[69],"variational":[71],"local-global":[73],"optical":[74],"flow":[75],"technique":[76],"to":[77,94,100,177],"determine":[78],"vector":[81],"field.":[82],"We":[83,108,121,141],"utilize":[84],"predicted":[86],"jointly":[89],"spatial":[91],"features":[93],"define":[95],"maximum":[97],"likelihood":[98],"criterion":[99],"find":[101],"inter-frame":[102],"correspondences":[104],"assuming":[105],"Markov":[106],"dependency.":[107],"formulate":[109],"event":[114],"as":[116],"graph":[118],"partitioning":[119],"problem.":[120],"propose":[122],"solution":[124],"obtained":[125],"minimization":[127],"global":[130],"cost":[131],"function":[132],"defined":[133],"over":[134],"set":[136],"all":[138],"tracks.":[140],"construct":[142],"tree":[146],"that":[147],"represents":[148],"tracks":[151],"events.":[154],"Finally,":[155],"compute":[157],"morphological,":[158],"motility,":[159],"diffusivity":[161],"measures":[162],"validate":[164],"against":[167],"manually":[168],"generated":[169],"reference":[170,178],"standards.":[171],"The":[172],"applied":[176],"maps":[180],"produces":[181,200],"an":[182,201],"average":[183,202],"accuracy":[185],"score":[186],"(":[187],"TRA)":[188],"99":[190],"percent,":[191],"system":[199],"TRA":[203],"89":[205],"percent.":[206]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":8},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}