{"id":"https://openalex.org/W29994482","doi":"https://doi.org/10.1109/tcbb.2018.2849708","title":"Ett \u00e4mne i utveckling : Idrotts\u00e4mnets utveckling och yrkets f\u00f6r\u00e4ndring mellan \u00e5ren 1962 - 2013","display_name":"Ett \u00e4mne i utveckling : Idrotts\u00e4mnets utveckling och yrkets f\u00f6r\u00e4ndring mellan \u00e5ren 1962 - 2013","publication_year":2014,"publication_date":"2014-01-01","ids":{"openalex":"https://openalex.org/W29994482","doi":"https://doi.org/10.1109/tcbb.2018.2849708","mag":"29994482"},"language":"en","primary_location":{"id":"mag:29994482","is_oa":false,"landing_page_url":"http://gih.diva-portal.org/smash/get/diva2:726680/FULLTEXT01","pdf_url":null,"source":{"id":"https://openalex.org/S36029991","display_name":"IEEE/ACM Transactions on Computational Biology and Bioinformatics","issn_l":"1545-5963","issn":["1545-5963","1557-9964","2374-0043"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE/ACM transactions on computational biology and bioinformatics","raw_type":null},"type":"article","indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://urn.kb.se/resolve?urn=urn:nbn:se:gih:diva-3342","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5003563784","display_name":"Philip Runsi\u00f6","orcid":null},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Philip Runsi\u00f6","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5058449146","display_name":"Sara Rudh","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sara Rudh","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5003563784"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.00676713,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"17","issue":"1","first_page":"165","last_page":"176"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11718","display_name":"Physical Education and Pedagogy","score":0.9502000212669373,"subfield":{"id":"https://openalex.org/subfields/3612","display_name":"Physical Therapy, Sports Therapy and Rehabilitation"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11718","display_name":"Physical Education and Pedagogy","score":0.9502000212669373,"subfield":{"id":"https://openalex.org/subfields/3612","display_name":"Physical Therapy, Sports Therapy and Rehabilitation"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/business-administration","display_name":"Business administration","score":0.48154810070991516},{"id":"https://openalex.org/keywords/political-science","display_name":"Political science","score":0.46217554807662964},{"id":"https://openalex.org/keywords/business","display_name":"Business","score":0.14909043908119202}],"concepts":[{"id":"https://openalex.org/C178550888","wikidata":"https://www.wikidata.org/wiki/Q2043282","display_name":"Business administration","level":1,"score":0.48154810070991516},{"id":"https://openalex.org/C17744445","wikidata":"https://www.wikidata.org/wiki/Q36442","display_name":"Political science","level":0,"score":0.46217554807662964},{"id":"https://openalex.org/C144133560","wikidata":"https://www.wikidata.org/wiki/Q4830453","display_name":"Business","level":0,"score":0.14909043908119202}],"mesh":[],"locations_count":2,"locations":[{"id":"mag:29994482","is_oa":false,"landing_page_url":"http://gih.diva-portal.org/smash/get/diva2:726680/FULLTEXT01","pdf_url":null,"source":{"id":"https://openalex.org/S36029991","display_name":"IEEE/ACM Transactions on Computational Biology and Bioinformatics","issn_l":"1545-5963","issn":["1545-5963","1557-9964","2374-0043"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE/ACM transactions on computational biology and bioinformatics","raw_type":null},{"id":"pmh:oai:DiVA.org:gih-3342","is_oa":true,"landing_page_url":"http://urn.kb.se/resolve?urn=urn:nbn:se:gih:diva-3342","pdf_url":null,"source":{"id":"https://openalex.org/S4306401559","display_name":"KTH Publication Database DiVA (KTH Royal Institute of Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"text"}],"best_oa_location":{"id":"pmh:oai:DiVA.org:gih-3342","is_oa":true,"landing_page_url":"http://urn.kb.se/resolve?urn=urn:nbn:se:gih:diva-3342","pdf_url":null,"source":{"id":"https://openalex.org/S4306401559","display_name":"KTH Publication Database DiVA (KTH Royal Institute of Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"text"},"sustainable_development_goals":[{"score":0.44999998807907104,"display_name":"Quality Education","id":"https://metadata.un.org/sdg/4"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":[],"abstract_inverted_index":{"Identifying":[0],"gene-drug":[1,68,173],"patterns":[2,174],"is":[3,129],"a":[4,31,73,130,176],"critical":[5],"step":[6],"in":[7,86,101,171],"pharmacology":[8],"for":[9],"unveiling":[10],"disease":[11],"mechanisms":[12],"and":[13,25,28,42,58,95,112,156,163],"drug":[14],"discovery.":[15],"The":[16,122],"availability":[17],"of":[18,110,119,125,169],"high-throughput":[19],"technologies":[20],"accumulates":[21],"massive":[22],"large-scale":[23,92,177],"pharmacological":[24,57],"genomic":[26,59],"data,":[27],"thus":[29],"provides":[30],"new":[32],"substantial":[33],"opportunity":[34],"to":[35,47,65,81,141],"deeply":[36],"understand":[37],"how":[38],"the":[39,43,56,67,87,91,106,117,126,167],"oncogenic":[40],"genes":[41,111],"therapeutic":[44],"drugs":[45,113],"relate":[46],"each":[48],"other.":[49],"However,":[50],"most":[51],"previous":[52],"studies":[53],"merely":[54],"used":[55],"datasets":[60],"without":[61],"any":[62],"prior":[63,108],"knowledge":[64],"infer":[66],"patterns.":[69],"Here,":[70],"we":[71],"proposed":[72],"novel":[74],"network-guided":[75],"sparse":[76],"binary":[77],"matching":[78],"model":[79,128],"(NSBM)":[80],"decode":[82],"these":[83],"relationships":[84],"hidden":[85],"datasets.":[88],"Not":[89],"only":[90],"gene-expression":[93],"data":[94,97,179],"drug-response":[96],"are":[98,114],"jointly":[99],"analyzed":[100],"our":[102],"method,":[103],"but":[104],"also":[105],"additional":[107],"information":[109],"integrated":[115],"into":[116],"form":[118],"network-based":[120,136],"regularization.":[121],"essential":[123],"structure":[124],"NSBM":[127,170],"convex":[131],"quadratic":[132],"minimization":[133],"problem":[134],"with":[135,146],"penalties.":[137],"It":[138],"was":[139],"demonstrated":[140],"be":[142],"superior":[143],"when":[144],"compared":[145],"two":[147],"benchmark":[148],"methods":[149],"through":[150],"extensive":[151],"experiments":[152],"on":[153,175],"both":[154],"synthetic":[155],"empirical":[157],"data.":[158],"Posterior":[159],"validation,":[160],"including":[161],"gene-ontology":[162],"enrichment":[164],"analysis,":[165],"confirmed":[166],"effectiveness":[168],"revealing":[172],"heterogeneous":[178],"source.":[180]},"counts_by_year":[],"updated_date":"2026-04-28T14:05:53.105641","created_date":"2025-10-10T00:00:00"}