{"id":"https://openalex.org/W2777175617","doi":"https://doi.org/10.1109/tcbb.2017.2786250","title":"Unsupervised Discovery of Geometrically Common Structural Motifs and Long-Range Contacts in Protein 3D Structures","display_name":"Unsupervised Discovery of Geometrically Common Structural Motifs and Long-Range Contacts in Protein 3D Structures","publication_year":2017,"publication_date":"2017-12-22","ids":{"openalex":"https://openalex.org/W2777175617","doi":"https://doi.org/10.1109/tcbb.2017.2786250","mag":"2777175617","pmid":"https://pubmed.ncbi.nlm.nih.gov/29990265"},"language":"en","primary_location":{"id":"doi:10.1109/tcbb.2017.2786250","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tcbb.2017.2786250","pdf_url":null,"source":{"id":"https://openalex.org/S36029991","display_name":"IEEE Transactions on Computational Biology and Bioinformatics","issn_l":"1545-5963","issn":["1545-5963","1557-9964","2374-0043","2998-4165"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE/ACM Transactions on Computational Biology and Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5084858146","display_name":"Florian Kaiser","orcid":"https://orcid.org/0000-0003-3775-081X"},"institutions":[{"id":"https://openalex.org/I116397343","display_name":"Hochschule Mittweida","ror":"https://ror.org/024ga3r86","country_code":"DE","type":"education","lineage":["https://openalex.org/I116397343"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Florian Kaiser","raw_affiliation_strings":["Department of Applied Computer and Biosciences, University of Applied Sciences Mittweida, Mittweida, Germany"],"raw_orcid":"https://orcid.org/0000-0003-3775-081X","affiliations":[{"raw_affiliation_string":"Department of Applied Computer and Biosciences, University of Applied Sciences Mittweida, Mittweida, Germany","institution_ids":["https://openalex.org/I116397343"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5023295736","display_name":"Dirk Labudde","orcid":"https://orcid.org/0000-0003-0466-0017"},"institutions":[{"id":"https://openalex.org/I116397343","display_name":"Hochschule Mittweida","ror":"https://ror.org/024ga3r86","country_code":"DE","type":"education","lineage":["https://openalex.org/I116397343"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Dirk Labudde","raw_affiliation_strings":["Department of Applied Computer and Biosciences, University of Applied Sciences Mittweida, Mittweida, Germany"],"raw_orcid":"https://orcid.org/0000-0003-0466-0017","affiliations":[{"raw_affiliation_string":"Department of Applied Computer and Biosciences, University of Applied Sciences Mittweida, Mittweida, Germany","institution_ids":["https://openalex.org/I116397343"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I116397343"],"apc_list":null,"apc_paid":null,"fwci":0.6082,"has_fulltext":false,"cited_by_count":6,"citation_normalized_percentile":{"value":0.66897777,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":97},"biblio":{"volume":"16","issue":"2","first_page":"671","last_page":"680"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.9973000288009644,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10519","display_name":"Advanced Proteomics Techniques and Applications","score":0.996399998664856,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/structural-motif","display_name":"Structural motif","score":0.720615804195404},{"id":"https://openalex.org/keywords/structural-bioinformatics","display_name":"Structural bioinformatics","score":0.6677581071853638},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.6144574880599976},{"id":"https://openalex.org/keywords/structural-similarity","display_name":"Structural similarity","score":0.5371229648590088},{"id":"https://openalex.org/keywords/protein-data-bank","display_name":"Protein Data Bank","score":0.5188754200935364},{"id":"https://openalex.org/keywords/proteases","display_name":"Proteases","score":0.5067816376686096},{"id":"https://openalex.org/keywords/protein-structure","display_name":"Protein structure","score":0.4826943874359131},{"id":"https://openalex.org/keywords/protein-folding","display_name":"Protein folding","score":0.4560527503490448},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.4494946002960205},{"id":"https://openalex.org/keywords/protein-structure-database","display_name":"Protein structure database","score":0.43481820821762085},{"id":"https://openalex.org/keywords/loop-modeling","display_name":"Loop modeling","score":0.43021607398986816},{"id":"https://openalex.org/keywords/a-priori-and-a-posteriori","display_name":"A priori and a posteriori","score":0.41314297914505005},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.3597431778907776},{"id":"https://openalex.org/keywords/protein-structure-prediction","display_name":"Protein structure prediction","score":0.3196137547492981},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.28795862197875977},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.2441382110118866},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.16512927412986755},{"id":"https://openalex.org/keywords/sequence-database","display_name":"Sequence database","score":0.14742052555084229},{"id":"https://openalex.org/keywords/biochemistry","display_name":"Biochemistry","score":0.12067338824272156},{"id":"https://openalex.org/keywords/enzyme","display_name":"Enzyme","score":0.10076212882995605}],"concepts":[{"id":"https://openalex.org/C132677234","wikidata":"https://www.wikidata.org/wiki/Q3273544","display_name":"Structural motif","level":2,"score":0.720615804195404},{"id":"https://openalex.org/C69131567","wikidata":"https://www.wikidata.org/wiki/Q2068215","display_name":"Structural bioinformatics","level":3,"score":0.6677581071853638},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.6144574880599976},{"id":"https://openalex.org/C139489369","wikidata":"https://www.wikidata.org/wiki/Q770846","display_name":"Structural similarity","level":2,"score":0.5371229648590088},{"id":"https://openalex.org/C119145174","wikidata":"https://www.wikidata.org/wiki/Q7251429","display_name":"Protein Data Bank","level":3,"score":0.5188754200935364},{"id":"https://openalex.org/C182220744","wikidata":"https://www.wikidata.org/wiki/Q7251226","display_name":"Proteases","level":3,"score":0.5067816376686096},{"id":"https://openalex.org/C47701112","wikidata":"https://www.wikidata.org/wiki/Q735188","display_name":"Protein structure","level":2,"score":0.4826943874359131},{"id":"https://openalex.org/C204328495","wikidata":"https://www.wikidata.org/wiki/Q847556","display_name":"Protein folding","level":2,"score":0.4560527503490448},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4494946002960205},{"id":"https://openalex.org/C136475424","wikidata":"https://www.wikidata.org/wiki/Q7251500","display_name":"Protein structure database","level":4,"score":0.43481820821762085},{"id":"https://openalex.org/C45475804","wikidata":"https://www.wikidata.org/wiki/Q6675846","display_name":"Loop modeling","level":4,"score":0.43021607398986816},{"id":"https://openalex.org/C75553542","wikidata":"https://www.wikidata.org/wiki/Q178161","display_name":"A priori and a posteriori","level":2,"score":0.41314297914505005},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.3597431778907776},{"id":"https://openalex.org/C18051474","wikidata":"https://www.wikidata.org/wiki/Q899656","display_name":"Protein structure prediction","level":3,"score":0.3196137547492981},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.28795862197875977},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.2441382110118866},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.16512927412986755},{"id":"https://openalex.org/C41584329","wikidata":"https://www.wikidata.org/wiki/Q175902","display_name":"Sequence database","level":3,"score":0.14742052555084229},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.12067338824272156},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.10076212882995605},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C111472728","wikidata":"https://www.wikidata.org/wiki/Q9471","display_name":"Epistemology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010363","descriptor_name":"Pattern Recognition, Automated","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D010363","descriptor_name":"Pattern Recognition, Automated","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D010363","descriptor_name":"Pattern Recognition, Automated","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020816","descriptor_name":"Amino Acid Motifs","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D020816","descriptor_name":"Amino Acid Motifs","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D020816","descriptor_name":"Amino Acid Motifs","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D020816","descriptor_name":"Amino Acid Motifs","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D020816","descriptor_name":"Amino Acid Motifs","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D020816","descriptor_name":"Amino Acid Motifs","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1109/tcbb.2017.2786250","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tcbb.2017.2786250","pdf_url":null,"source":{"id":"https://openalex.org/S36029991","display_name":"IEEE Transactions on Computational Biology and Bioinformatics","issn_l":"1545-5963","issn":["1545-5963","1557-9964","2374-0043","2998-4165"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE/ACM Transactions on Computational Biology and Bioinformatics","raw_type":"journal-article"},{"id":"pmid:29990265","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29990265","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE/ACM transactions on computational biology and bioinformatics","raw_type":null},{"id":"pmh:oai:fraunhofer.de:N-633674","is_oa":false,"landing_page_url":"http://publica.fraunhofer.de/documents/N-633674.html","pdf_url":null,"source":{"id":"https://openalex.org/S4306400801","display_name":"Publikationsdatenbank der Fraunhofer-Gesellschaft (Fraunhofer-Gesellschaft)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4923324","host_organization_name":"Fraunhofer-Gesellschaft","host_organization_lineage":["https://openalex.org/I4923324"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Fraunhofer SIT","raw_type":"Journal Article"},{"id":"pmh:oai:publica.fraunhofer.de:publica/266713","is_oa":false,"landing_page_url":"https://publica.fraunhofer.de/handle/publica/266713","pdf_url":null,"source":{"id":"https://openalex.org/S4306400318","display_name":"Fraunhofer-Publica (Fraunhofer-Gesellschaft)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4923324","host_organization_name":"Fraunhofer-Gesellschaft","host_organization_lineage":["https://openalex.org/I4923324"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"journal article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320321613","display_name":"Technische Universit\u00e4t Dresden","ror":"https://ror.org/042aqky30"},{"id":"https://openalex.org/F4320328735","display_name":"Freistaat Sachsen","ror":null},{"id":"https://openalex.org/F4320334763","display_name":"Leibniz-Gemeinschaft","ror":"https://ror.org/01n6r0e97"},{"id":"https://openalex.org/F4320338080","display_name":"European Social Fund","ror":"https://ror.org/00k4n6c32"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":60,"referenced_works":["https://openalex.org/W1482509850","https://openalex.org/W1506285740","https://openalex.org/W1517953913","https://openalex.org/W1531234455","https://openalex.org/W1606594487","https://openalex.org/W1849980826","https://openalex.org/W1963553206","https://openalex.org/W1965910641","https://openalex.org/W1972748570","https://openalex.org/W1979871945","https://openalex.org/W1982309045","https://openalex.org/W1986154009","https://openalex.org/W1986969007","https://openalex.org/W1994697790","https://openalex.org/W1997168556","https://openalex.org/W1999319994","https://openalex.org/W2003301106","https://openalex.org/W2012009921","https://openalex.org/W2014474863","https://openalex.org/W2015147525","https://openalex.org/W2024656312","https://openalex.org/W2024732820","https://openalex.org/W2024993723","https://openalex.org/W2025816743","https://openalex.org/W2031194866","https://openalex.org/W2044284701","https://openalex.org/W2045119694","https://openalex.org/W2047172988","https://openalex.org/W2047544230","https://openalex.org/W2054534830","https://openalex.org/W2059981954","https://openalex.org/W2061685714","https://openalex.org/W2072290128","https://openalex.org/W2091861424","https://openalex.org/W2096344315","https://openalex.org/W2107005225","https://openalex.org/W2107327414","https://openalex.org/W2108107014","https://openalex.org/W2110483430","https://openalex.org/W2115482638","https://openalex.org/W2117164735","https://openalex.org/W2122976061","https://openalex.org/W2129020329","https://openalex.org/W2131374321","https://openalex.org/W2132109794","https://openalex.org/W2133452849","https://openalex.org/W2138770756","https://openalex.org/W2140890018","https://openalex.org/W2140992384","https://openalex.org/W2149625704","https://openalex.org/W2159560083","https://openalex.org/W2160672469","https://openalex.org/W2179694298","https://openalex.org/W2224056471","https://openalex.org/W2229908198","https://openalex.org/W2339091785","https://openalex.org/W2562997947","https://openalex.org/W2574496196","https://openalex.org/W6630198464","https://openalex.org/W6689475862"],"related_works":["https://openalex.org/W2146442590","https://openalex.org/W4388749535","https://openalex.org/W2121688928","https://openalex.org/W3013234621","https://openalex.org/W2607853144","https://openalex.org/W2013950502","https://openalex.org/W4285340733","https://openalex.org/W4389309199","https://openalex.org/W1997379747","https://openalex.org/W2777175617"],"abstract_inverted_index":{"The":[0,124],"essential":[1],"role":[2],"of":[3,33,67,75,84,98,126,134,138,145,150,160,165,187],"small":[4],"evolutionarily":[5],"conserved":[6],"structural":[7,47,76,96,162,188],"units":[8],"in":[9,106],"proteins":[10],"has":[11],"been":[12],"extensively":[13],"researched":[14],"and":[15,53,87,102,141,182],"validated.":[16],"A":[17],"popular":[18],"example":[19],"are":[20,49],"serine":[21,139],"proteases,":[22],"where":[23],"the":[24,42,63,72,82,127,132,135,142,151,158],"peptide":[25],"cleavage":[26],"reaction":[27],"is":[28,122,129,176],"realized":[29],"by":[30,131],"a":[31,92,119],"configuration":[32],"only":[34],"three":[35],"residues.":[36],"Brought":[37],"to":[38,56,62,81,94,178,183,194],"spatial":[39],"proximity":[40],"during":[41],"protein":[43,68,85,107,196],"folding":[44],"process,":[45],"such":[46],"motifs":[48,77,97],"often":[50],"long-range":[51],"contacts":[52],"usually":[54],"hard":[55],"detect":[57],"at":[58],"sequence":[59,104],"level.":[60],"Due":[61],"constantly":[64],"increasing":[65],"resource":[66],"3D":[69,108],"structure":[70,109],"data,":[71],"computational":[73],"identification":[74,133],"can":[78],"contribute":[79],"significantly":[80],"understanding":[83],"fold":[86,168],"function.":[88,170],"Thus,":[89],"we":[90],"propose":[91],"method":[93,128,175],"discover":[95],"high":[99],"geometrical":[100],"similarity":[101],"desired":[103],"separation":[105],"data.":[110],"By":[111],"utilizing":[112],"methods":[113],"originated":[114],"from":[115],"data":[116],"mining,":[117],"no":[118],"priori":[120],"knowledge":[121],"required.":[123],"applicability":[125],"demonstrated":[130],"catalytic":[136],"unit":[137],"proteases":[140],"ion-coordination":[143],"center":[144],"cupredoxins.":[146],"Furthermore,":[147],"large-scale":[148],"analysis":[149],"entire":[152],"Protein":[153],"Data":[154],"Bank":[155],"points":[156],"towards":[157],"presence":[159],"ubiquitous":[161],"motifs,":[163,189],"independent":[164],"any":[166],"specific":[167],"or":[169],"We":[171],"envision":[172],"that":[173],"our":[174],"suitable":[177],"uncover":[179],"functional":[180],"mechanisms":[181],"derive":[184],"fingerprint":[185],"libraries":[186],"which":[190],"could":[191],"be":[192],"used":[193],"assess":[195],"family":[197],"association.":[198]},"counts_by_year":[{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":3}],"updated_date":"2026-07-30T17:31:21.811387","created_date":"2025-10-10T00:00:00"}