{"id":"https://openalex.org/W2761077903","doi":"https://doi.org/10.1109/tcbb.2017.2760827","title":"Novel Consensus Gene Selection Criteria for Distributed GPU Partial Least Squares-Based Gene Microarray Analysis in Diffused Large B Cell Lymphoma (DLBCL) and Related Findings","display_name":"Novel Consensus Gene Selection Criteria for Distributed GPU Partial Least Squares-Based Gene Microarray Analysis in Diffused Large B Cell Lymphoma (DLBCL) and Related Findings","publication_year":2017,"publication_date":"2017-10-09","ids":{"openalex":"https://openalex.org/W2761077903","doi":"https://doi.org/10.1109/tcbb.2017.2760827","mag":"2761077903","pmid":"https://pubmed.ncbi.nlm.nih.gov/28991749"},"language":"en","primary_location":{"id":"doi:10.1109/tcbb.2017.2760827","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tcbb.2017.2760827","pdf_url":null,"source":{"id":"https://openalex.org/S36029991","display_name":"IEEE Transactions on Computational Biology and Bioinformatics","issn_l":"1545-5963","issn":["1545-5963","1557-9964","2374-0043","2998-4165"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE/ACM Transactions on Computational Biology and Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101830959","display_name":"H. C. Wu","orcid":"https://orcid.org/0000-0002-4555-3675"},"institutions":[{"id":"https://openalex.org/I889458895","display_name":"University of Hong Kong","ror":"https://ror.org/02zhqgq86","country_code":"HK","type":"education","lineage":["https://openalex.org/I889458895"]}],"countries":["HK"],"is_corresponding":false,"raw_author_name":"Ho-Chun Wu","raw_affiliation_strings":["Department of Electrical and Electronic Engineering, The University of Hong Kong, Hong Kong"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Electrical and Electronic Engineering, The University of Hong Kong, Hong Kong","institution_ids":["https://openalex.org/I889458895"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090893791","display_name":"Xi-Guang Wei","orcid":null},"institutions":[{"id":"https://openalex.org/I889458895","display_name":"University of Hong Kong","ror":"https://ror.org/02zhqgq86","country_code":"HK","type":"education","lineage":["https://openalex.org/I889458895"]}],"countries":["HK"],"is_corresponding":false,"raw_author_name":"Xi-Guang Wei","raw_affiliation_strings":["Department of Electrical and Electronic Engineering, The University of Hong Kong, Hong Kong"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Electrical and Electronic Engineering, The University of Hong Kong, Hong Kong","institution_ids":["https://openalex.org/I889458895"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5057049452","display_name":"S. C. Chan","orcid":"https://orcid.org/0000-0001-7212-4182"},"institutions":[{"id":"https://openalex.org/I889458895","display_name":"University of Hong Kong","ror":"https://ror.org/02zhqgq86","country_code":"HK","type":"education","lineage":["https://openalex.org/I889458895"]}],"countries":["HK"],"is_corresponding":false,"raw_author_name":"Shing-Chow Chan","raw_affiliation_strings":["Department of Electrical and Electronic Engineering, The University of Hong Kong, Hong Kong"],"raw_orcid":"https://orcid.org/0000-0001-7212-4182","affiliations":[{"raw_affiliation_string":"Department of Electrical and Electronic Engineering, The University of Hong Kong, Hong Kong","institution_ids":["https://openalex.org/I889458895"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I889458895"],"apc_list":null,"apc_paid":null,"fwci":0.9124,"has_fulltext":false,"cited_by_count":15,"citation_normalized_percentile":{"value":0.73332422,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"15","issue":"6","first_page":"2039","last_page":"2052"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9915000200271606,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11970","display_name":"Molecular Biology Techniques and Applications","score":0.9860000014305115,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gene-selection","display_name":"Gene selection","score":0.5888431668281555},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5297459363937378},{"id":"https://openalex.org/keywords/microarray-analysis-techniques","display_name":"Microarray analysis techniques","score":0.5093594789505005},{"id":"https://openalex.org/keywords/significance-analysis-of-microarrays","display_name":"Significance analysis of microarrays","score":0.49749448895454407},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.4861571490764618},{"id":"https://openalex.org/keywords/selection","display_name":"Selection (genetic algorithm)","score":0.4632837176322937},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.4524562954902649},{"id":"https://openalex.org/keywords/microarray","display_name":"Microarray","score":0.41811490058898926},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.3642374575138092},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.2953410744667053},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.2093716263771057},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.1821208894252777},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.17639487981796265}],"concepts":[{"id":"https://openalex.org/C2984324147","wikidata":"https://www.wikidata.org/wiki/Q3080021","display_name":"Gene selection","level":5,"score":0.5888431668281555},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5297459363937378},{"id":"https://openalex.org/C8415881","wikidata":"https://www.wikidata.org/wiki/Q6839217","display_name":"Microarray analysis techniques","level":4,"score":0.5093594789505005},{"id":"https://openalex.org/C77360908","wikidata":"https://www.wikidata.org/wiki/Q6839217","display_name":"Significance analysis of microarrays","level":5,"score":0.49749448895454407},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4861571490764618},{"id":"https://openalex.org/C81917197","wikidata":"https://www.wikidata.org/wiki/Q628760","display_name":"Selection (genetic algorithm)","level":2,"score":0.4632837176322937},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.4524562954902649},{"id":"https://openalex.org/C186836561","wikidata":"https://www.wikidata.org/wiki/Q1931516","display_name":"Microarray","level":4,"score":0.41811490058898926},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.3642374575138092},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2953410744667053},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.2093716263771057},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.1821208894252777},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.17639487981796265}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016018","descriptor_name":"Least-Squares Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016018","descriptor_name":"Least-Squares Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016018","descriptor_name":"Least-Squares Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016393","descriptor_name":"Lymphoma, B-Cell","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D016393","descriptor_name":"Lymphoma, B-Cell","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D016393","descriptor_name":"Lymphoma, B-Cell","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D016393","descriptor_name":"Lymphoma, B-Cell","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D016393","descriptor_name":"Lymphoma, B-Cell","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D016393","descriptor_name":"Lymphoma, B-Cell","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1109/tcbb.2017.2760827","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tcbb.2017.2760827","pdf_url":null,"source":{"id":"https://openalex.org/S36029991","display_name":"IEEE Transactions on Computational Biology and Bioinformatics","issn_l":"1545-5963","issn":["1545-5963","1557-9964","2374-0043","2998-4165"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE/ACM Transactions on Computational Biology and Bioinformatics","raw_type":"journal-article"},{"id":"pmid:28991749","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28991749","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE/ACM transactions on computational biology and bioinformatics","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":71,"referenced_works":["https://openalex.org/W86601866","https://openalex.org/W182538937","https://openalex.org/W585828296","https://openalex.org/W643606810","https://openalex.org/W1479974475","https://openalex.org/W1533179050","https://openalex.org/W1555620806","https://openalex.org/W1903565876","https://openalex.org/W1964042173","https://openalex.org/W1973552307","https://openalex.org/W1976169036","https://openalex.org/W1978218402","https://openalex.org/W1985645817","https://openalex.org/W1987522787","https://openalex.org/W1990557296","https://openalex.org/W2001475156","https://openalex.org/W2009431295","https://openalex.org/W2010739896","https://openalex.org/W2013223495","https://openalex.org/W2020221926","https://openalex.org/W2035115173","https://openalex.org/W2041652340","https://openalex.org/W2041905383","https://openalex.org/W2042788150","https://openalex.org/W2044385569","https://openalex.org/W2047614366","https://openalex.org/W2056383219","https://openalex.org/W2064208261","https://openalex.org/W2070831760","https://openalex.org/W2072203820","https://openalex.org/W2073792037","https://openalex.org/W2085353600","https://openalex.org/W2087684630","https://openalex.org/W2087771752","https://openalex.org/W2092974902","https://openalex.org/W2096158882","https://openalex.org/W2105672886","https://openalex.org/W2109363337","https://openalex.org/W2115291479","https://openalex.org/W2117692326","https://openalex.org/W2119772009","https://openalex.org/W2123363536","https://openalex.org/W2127938920","https://openalex.org/W2130410032","https://openalex.org/W2133465414","https://openalex.org/W2141007997","https://openalex.org/W2141826465","https://openalex.org/W2143426320","https://openalex.org/W2144751786","https://openalex.org/W2151990594","https://openalex.org/W2156764287","https://openalex.org/W2157672977","https://openalex.org/W2158137698","https://openalex.org/W2158217645","https://openalex.org/W2159365351","https://openalex.org/W2159400887","https://openalex.org/W2165250079","https://openalex.org/W2170522882","https://openalex.org/W2181470043","https://openalex.org/W2256589830","https://openalex.org/W2316564661","https://openalex.org/W2580999664","https://openalex.org/W2612575796","https://openalex.org/W2793337497","https://openalex.org/W3016236341","https://openalex.org/W3125904670","https://openalex.org/W4248113696","https://openalex.org/W6607482586","https://openalex.org/W6683942726","https://openalex.org/W6686240244","https://openalex.org/W6732482000"],"related_works":["https://openalex.org/W2796636403","https://openalex.org/W2015700328","https://openalex.org/W2364565895","https://openalex.org/W2767847608","https://openalex.org/W2911678823","https://openalex.org/W2152648570","https://openalex.org/W2037892364","https://openalex.org/W2319154570","https://openalex.org/W3152114242","https://openalex.org/W2541368543"],"abstract_inverted_index":{"This":[0],"paper":[1],"proposes":[2],"a":[3,51],"novel":[4],"consensus":[5],"gene":[6,13,27,70,93,144,177,192],"selection":[7,71],"criteria":[8,46],"for":[9,122,161,186],"partial":[10],"least":[11],"squares-based":[12],"microarray":[14,85,94],"analysis.":[15],"By":[16],"quantifying":[17],"the":[18,25,44,57,69,84,98,119,137,165,176,180],"extent":[19],"of":[20,24,39,175],"consistency":[21],"and":[22,41,73,129,133,164,171],"distinctiveness":[23],"differential":[26],"expressions":[28],"across":[29],"different":[30,148],"double":[31],"cross":[32],"validations":[33],"(CV)":[34],"or":[35,195],"randomizations":[36],"in":[37,109,147,169],"terms":[38],"occurrence":[40],"randomization":[42],"p-values,":[43],"proposed":[45,66,99,138,181],"are":[47],"able":[48,102,141],"to":[49,67,103,142],"identify":[50,143],"more":[52],"comprehensive":[53],"genes":[54,121],"associated":[55],"with":[56,111,150],"underlying":[58],"disease.":[59],"A":[60],"Distributed":[61],"GPU":[62],"implementation":[63],"has":[64,79],"been":[65,80],"accelerate":[68],"problem":[72],"about":[74],"8-11":[75],"times":[76],"speed":[77],"up":[78],"achieved":[81],"based":[82,190],"on":[83,118,191],"datasets":[86,95,132],"considered.":[87],"Simulation":[88],"results":[89],"using":[90],"various":[91],"cancer":[92,187],"show":[96,134],"that":[97,135],"approach":[100,139,182],"is":[101,140],"achieve":[104],"highly":[105],"comparable":[106],"classification":[107],"accuracy":[108],"comparing":[110],"many":[112],"conventional":[113,162],"approaches.":[114],"Furthermore,":[115],"enrichment":[116],"analysis":[117],"selected":[120],"Diffused":[123],"Large":[124],"B":[125],"Cell":[126],"Lymphoma":[127],"(DLBCL)":[128],"Prostate":[130],"Cancer":[131],"only":[136],"lists":[145],"enriched":[146],"pathways":[149],"significant":[151],"p-values.":[152],"In":[153],"contrast,":[154],"sufficient":[155],"statistical":[156,173],"significance":[157,174],"cannot":[158],"be":[159],"found":[160],"SVM-RFE":[163],"t-test.":[166],"The":[167],"reliability":[168],"identifying":[170],"establishing":[172],"findings":[178],"makes":[179],"an":[183],"attractive":[184],"alternative":[185],"related":[188],"researches":[189],"expression":[193],"profiling":[194],"other":[196],"similar":[197],"data.":[198]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":1}],"updated_date":"2026-07-30T17:31:21.811387","created_date":"2025-10-10T00:00:00"}
