{"id":"https://openalex.org/W2277509832","doi":"https://doi.org/10.1109/tcbb.2015.2446478","title":"Examining De Novo Transcriptome Assemblies via a Quality Assessment Pipeline","display_name":"Examining De Novo Transcriptome Assemblies via a Quality Assessment Pipeline","publication_year":2015,"publication_date":"2015-06-17","ids":{"openalex":"https://openalex.org/W2277509832","doi":"https://doi.org/10.1109/tcbb.2015.2446478","mag":"2277509832","pmid":"https://pubmed.ncbi.nlm.nih.gov/29610098"},"language":"en","primary_location":{"id":"doi:10.1109/tcbb.2015.2446478","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tcbb.2015.2446478","pdf_url":null,"source":{"id":"https://openalex.org/S36029991","display_name":"IEEE/ACM Transactions on Computational Biology and Bioinformatics","issn_l":"1545-5963","issn":["1545-5963","1557-9964","2374-0043"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE/ACM Transactions on Computational Biology and Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5088517574","display_name":"Noushin Ghaffari","orcid":"https://orcid.org/0000-0001-5354-5643"},"institutions":[{"id":"https://openalex.org/I91045830","display_name":"Texas A&M University","ror":"https://ror.org/01f5ytq51","country_code":"US","type":"education","lineage":["https://openalex.org/I91045830"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Noushin Ghaffari","raw_affiliation_strings":["AgriLife Genomics and Bioinformatics, Texas A&M University, College Station, TX, USA"],"affiliations":[{"raw_affiliation_string":"AgriLife Genomics and Bioinformatics, Texas A&M University, College Station, TX, USA","institution_ids":["https://openalex.org/I91045830"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062394853","display_name":"Osama A. Arshad","orcid":null},"institutions":[{"id":"https://openalex.org/I91045830","display_name":"Texas A&M University","ror":"https://ror.org/01f5ytq51","country_code":"US","type":"education","lineage":["https://openalex.org/I91045830"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Osama A. Arshad","raw_affiliation_strings":["Department of Electrical and Computer Engineering, Texas A&M University, College Station, TX, USA"],"affiliations":[{"raw_affiliation_string":"Department of Electrical and Computer Engineering, Texas A&M University, College Station, TX, USA","institution_ids":["https://openalex.org/I91045830"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080014317","display_name":"Hyundoo Jeong","orcid":"https://orcid.org/0000-0002-5641-8620"},"institutions":[{"id":"https://openalex.org/I91045830","display_name":"Texas A&M University","ror":"https://ror.org/01f5ytq51","country_code":"US","type":"education","lineage":["https://openalex.org/I91045830"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hyundoo Jeong","raw_affiliation_strings":["Department of Electrical and Computer Engineering, Texas A&M University, College Station, TX, USA"],"affiliations":[{"raw_affiliation_string":"Department of Electrical and Computer Engineering, Texas A&M University, College Station, TX, USA","institution_ids":["https://openalex.org/I91045830"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062258810","display_name":"John Thiltges","orcid":null},"institutions":[{"id":"https://openalex.org/I91045830","display_name":"Texas A&M University","ror":"https://ror.org/01f5ytq51","country_code":"US","type":"education","lineage":["https://openalex.org/I91045830"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"John Thiltges","raw_affiliation_strings":["AgriLife Genomics and Bioinformatics, Texas A&M University, College Station, TX, USA"],"affiliations":[{"raw_affiliation_string":"AgriLife Genomics and Bioinformatics, Texas A&M University, College Station, TX, USA","institution_ids":["https://openalex.org/I91045830"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091727400","display_name":"Michael F. Criscitiello","orcid":"https://orcid.org/0000-0003-4262-7832"},"institutions":[{"id":"https://openalex.org/I91045830","display_name":"Texas A&M University","ror":"https://ror.org/01f5ytq51","country_code":"US","type":"education","lineage":["https://openalex.org/I91045830"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael F. Criscitiello","raw_affiliation_strings":["Comparative Immunogenetics Laboratory, Texas A&M University, College Station, TX, USA"],"affiliations":[{"raw_affiliation_string":"Comparative Immunogenetics Laboratory, Texas A&M University, College Station, TX, USA","institution_ids":["https://openalex.org/I91045830"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081620315","display_name":"Byung-Jun Yoon","orcid":"https://orcid.org/0000-0001-9328-1101"},"institutions":[{"id":"https://openalex.org/I4210144839","display_name":"Hamad bin Khalifa University","ror":"https://ror.org/03eyq4y97","country_code":"QA","type":"education","lineage":["https://openalex.org/I4210144839"]},{"id":"https://openalex.org/I91045830","display_name":"Texas A&M University","ror":"https://ror.org/01f5ytq51","country_code":"US","type":"education","lineage":["https://openalex.org/I91045830"]}],"countries":["QA","US"],"is_corresponding":false,"raw_author_name":"Byung-Jun Yoon","raw_affiliation_strings":["College of Science and Engineering, Hamad bin Khalifa University (HBKU), Doha, Qatar","Department of Electrical and Computer Engineering, Texas A&M University, College Station, TX, USA"],"affiliations":[{"raw_affiliation_string":"College of Science and Engineering, Hamad bin Khalifa University (HBKU), Doha, Qatar","institution_ids":["https://openalex.org/I4210144839"]},{"raw_affiliation_string":"Department of Electrical and Computer Engineering, Texas A&M University, College Station, TX, USA","institution_ids":["https://openalex.org/I91045830"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045462352","display_name":"Aniruddha Datta","orcid":"https://orcid.org/0000-0003-1213-3807"},"institutions":[{"id":"https://openalex.org/I91045830","display_name":"Texas A&M University","ror":"https://ror.org/01f5ytq51","country_code":"US","type":"education","lineage":["https://openalex.org/I91045830"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Aniruddha Datta","raw_affiliation_strings":["Department of Electrical and Computer Engineering, Texas A&M University, College Station, TX, USA"],"affiliations":[{"raw_affiliation_string":"Department of Electrical and Computer Engineering, Texas A&M University, College Station, TX, USA","institution_ids":["https://openalex.org/I91045830"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5055316781","display_name":"Charles D. Johnson","orcid":"https://orcid.org/0000-0003-3892-7082"},"institutions":[{"id":"https://openalex.org/I91045830","display_name":"Texas A&M University","ror":"https://ror.org/01f5ytq51","country_code":"US","type":"education","lineage":["https://openalex.org/I91045830"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Charles D. Johnson","raw_affiliation_strings":["AgriLife Genomics and Bioinformatics, Texas A&M University, College Station, TX, USA"],"affiliations":[{"raw_affiliation_string":"AgriLife Genomics and Bioinformatics, Texas A&M University, College Station, TX, USA","institution_ids":["https://openalex.org/I91045830"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5088517574"],"corresponding_institution_ids":["https://openalex.org/I91045830"],"apc_list":null,"apc_paid":null,"fwci":0.8752,"has_fulltext":false,"cited_by_count":6,"citation_normalized_percentile":{"value":0.74485942,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":96},"biblio":{"volume":"15","issue":"2","first_page":"494","last_page":"505"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10506","display_name":"Aquaculture disease management and microbiota","score":0.9922999739646912,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9879000186920166,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/transcriptome","display_name":"Transcriptome","score":0.804208517074585},{"id":"https://openalex.org/keywords/de-novo-transcriptome-assembly","display_name":"De novo transcriptome assembly","score":0.7309798002243042},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5422734618186951},{"id":"https://openalex.org/keywords/sequence-assembly","display_name":"Sequence assembly","score":0.5414348840713501},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.5237305760383606},{"id":"https://openalex.org/keywords/workflow","display_name":"Workflow","score":0.5163692235946655},{"id":"https://openalex.org/keywords/quality","display_name":"Quality (philosophy)","score":0.49030163884162903},{"id":"https://openalex.org/keywords/annotation","display_name":"Annotation","score":0.48317161202430725},{"id":"https://openalex.org/keywords/genome","display_name":"Genome","score":0.44085124135017395},{"id":"https://openalex.org/keywords/pipeline","display_name":"Pipeline (software)","score":0.44054117798805237},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.41514405608177185},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.28153330087661743},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.25676047801971436},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.23388129472732544},{"id":"https://openalex.org/keywords/database","display_name":"Database","score":0.11139810085296631},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.07307976484298706}],"concepts":[{"id":"https://openalex.org/C162317418","wikidata":"https://www.wikidata.org/wiki/Q252857","display_name":"Transcriptome","level":4,"score":0.804208517074585},{"id":"https://openalex.org/C50489715","wikidata":"https://www.wikidata.org/wiki/Q5244960","display_name":"De novo transcriptome assembly","level":5,"score":0.7309798002243042},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5422734618186951},{"id":"https://openalex.org/C18949551","wikidata":"https://www.wikidata.org/wiki/Q740578","display_name":"Sequence assembly","level":5,"score":0.5414348840713501},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5237305760383606},{"id":"https://openalex.org/C177212765","wikidata":"https://www.wikidata.org/wiki/Q627335","display_name":"Workflow","level":2,"score":0.5163692235946655},{"id":"https://openalex.org/C2779530757","wikidata":"https://www.wikidata.org/wiki/Q1207505","display_name":"Quality (philosophy)","level":2,"score":0.49030163884162903},{"id":"https://openalex.org/C2776321320","wikidata":"https://www.wikidata.org/wiki/Q857525","display_name":"Annotation","level":2,"score":0.48317161202430725},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.44085124135017395},{"id":"https://openalex.org/C43521106","wikidata":"https://www.wikidata.org/wiki/Q2165493","display_name":"Pipeline (software)","level":2,"score":0.44054117798805237},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.41514405608177185},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.28153330087661743},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.25676047801971436},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.23388129472732544},{"id":"https://openalex.org/C77088390","wikidata":"https://www.wikidata.org/wiki/Q8513","display_name":"Database","level":1,"score":0.11139810085296631},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.07307976484298706},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C111472728","wikidata":"https://www.wikidata.org/wiki/Q9471","display_name":"Epistemology","level":1,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000073359","descriptor_name":"Exome Sequencing","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D000073359","descriptor_name":"Exome Sequencing","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D000073359","descriptor_name":"Exome Sequencing","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D033561","descriptor_name":"Penaeidae","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D033561","descriptor_name":"Penaeidae","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D033561","descriptor_name":"Penaeidae","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D059467","descriptor_name":"Transcriptome","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D059467","descriptor_name":"Transcriptome","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D059467","descriptor_name":"Transcriptome","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1109/tcbb.2015.2446478","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tcbb.2015.2446478","pdf_url":null,"source":{"id":"https://openalex.org/S36029991","display_name":"IEEE/ACM Transactions on Computational Biology and Bioinformatics","issn_l":"1545-5963","issn":["1545-5963","1557-9964","2374-0043"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE/ACM Transactions on Computational Biology and Bioinformatics","raw_type":"journal-article"},{"id":"pmid:29610098","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29610098","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE/ACM transactions on computational biology and bioinformatics","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.4000000059604645,"display_name":"Life below water","id":"https://metadata.un.org/sdg/14"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320309549","display_name":"University of Houston","ror":"https://ror.org/040vwpm13"},{"id":"https://openalex.org/F4320310164","display_name":"Texas A and M University","ror":"https://ror.org/01f5ytq51"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":55,"referenced_works":["https://openalex.org/W1577982243","https://openalex.org/W1891659677","https://openalex.org/W1971899779","https://openalex.org/W1974882189","https://openalex.org/W1975912699","https://openalex.org/W1976247738","https://openalex.org/W1982717654","https://openalex.org/W1984238703","https://openalex.org/W1989746162","https://openalex.org/W1996370379","https://openalex.org/W1998950108","https://openalex.org/W1999261039","https://openalex.org/W1999360828","https://openalex.org/W2012016911","https://openalex.org/W2013612931","https://openalex.org/W2025804323","https://openalex.org/W2028384803","https://openalex.org/W2041956242","https://openalex.org/W2043549283","https://openalex.org/W2048783574","https://openalex.org/W2050864553","https://openalex.org/W2067786443","https://openalex.org/W2069001768","https://openalex.org/W2072031679","https://openalex.org/W2072528438","https://openalex.org/W2083770400","https://openalex.org/W2085179890","https://openalex.org/W2090610796","https://openalex.org/W2097117811","https://openalex.org/W2097834295","https://openalex.org/W2100703845","https://openalex.org/W2101467247","https://openalex.org/W2101786683","https://openalex.org/W2102863305","https://openalex.org/W2103139806","https://openalex.org/W2103148772","https://openalex.org/W2103635790","https://openalex.org/W2109636763","https://openalex.org/W2116212096","https://openalex.org/W2120457919","https://openalex.org/W2124957468","https://openalex.org/W2126419817","https://openalex.org/W2127963635","https://openalex.org/W2128222086","https://openalex.org/W2130165325","https://openalex.org/W2139747296","https://openalex.org/W2140466922","https://openalex.org/W2140544891","https://openalex.org/W2152556446","https://openalex.org/W2153805460","https://openalex.org/W2154431984","https://openalex.org/W2155201678","https://openalex.org/W2156841387","https://openalex.org/W2160525528","https://openalex.org/W2170551349"],"related_works":["https://openalex.org/W1021674602","https://openalex.org/W2049364822","https://openalex.org/W233273322","https://openalex.org/W4213449093","https://openalex.org/W2757402142","https://openalex.org/W2140544891","https://openalex.org/W3157557088","https://openalex.org/W4206729893","https://openalex.org/W3111299424","https://openalex.org/W3205879304"],"abstract_inverted_index":{"New":[0],"de":[1,31],"novo":[2,32],"transcriptome":[3,15,33,56,81,111],"assembly":[4,34,76,131],"and":[5,22,83,99,102,116,153],"annotation":[6],"methods":[7],"provide":[8,70,117],"an":[9,20,118,130],"incredible":[10],"opportunity":[11],"to":[12,41,50],"study":[13],"the":[14,43,52,55,75,127,135],"of":[16,30,45,54,62,74,129,149],"organisms":[17],"that":[18,67,125,147],"lack":[19],"assembled":[21],"annotated":[23],"genome.":[24],"There":[25],"are":[26],"currently":[27],"a":[28,60,71,93,144],"number":[29],"methods,":[35],"but":[36],"it":[37],"has":[38],"been":[39],"difficult":[40],"evaluate":[42],"quality":[44,53,64,128,151],"these":[46],"assemblies.":[47],"In":[48],"order":[49],"assess":[51],"assemblies,":[57],"we":[58,142],"composed":[59],"workflow":[61],"multiple":[63,114],"check":[65],"measurements":[66,138],"in":[68],"combination":[69],"clear":[72],"evaluation":[73],"performance.":[77],"We":[78,107],"presented":[79],"novel":[80],"assemblies":[82,112],"functional":[84],"annotations":[85],"for":[86],"Pacific":[87,109],"Whiteleg":[88,110],"Shrimp":[89],"(Litopenaeus":[90],"vannamei":[91],"),":[92],"mariculture":[94],"species":[95],"with":[96],"great":[97],"national":[98],"international":[100],"interest,":[101],"no":[103],"solid":[104],"transcriptome/genome":[105],"reference.":[106],"examined":[108],"via":[113],"metrics,":[115],"improved":[119],"gene":[120],"annotation.":[121],"Our":[122],"investigations":[123],"show":[124],"assessing":[126],"purely":[132],"based":[133],"on":[134],"assembler's":[136],"statistical":[137,150],"can":[139],"be":[140],"misleading;":[141],"propose":[143],"hybrid":[145],"approach":[146],"consists":[148],"checks":[152],"further":[154],"biological-based":[155],"evaluations.":[156]},"counts_by_year":[{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":2}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}