{"id":"https://openalex.org/W2063692638","doi":"https://doi.org/10.1109/tcbb.2015.2389213","title":"An Integrated Framework for Functional Annotation of Protein Structural Domains","display_name":"An Integrated Framework for Functional Annotation of Protein Structural Domains","publication_year":2015,"publication_date":"2015-01-08","ids":{"openalex":"https://openalex.org/W2063692638","doi":"https://doi.org/10.1109/tcbb.2015.2389213","mag":"2063692638","pmid":"https://pubmed.ncbi.nlm.nih.gov/26357331"},"language":"en","primary_location":{"id":"doi:10.1109/tcbb.2015.2389213","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tcbb.2015.2389213","pdf_url":null,"source":{"id":"https://openalex.org/S36029991","display_name":"IEEE Transactions on Computational Biology and Bioinformatics","issn_l":"1545-5963","issn":["1545-5963","1557-9964","2374-0043","2998-4165"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE/ACM Transactions on Computational Biology and Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5085608332","display_name":"Lei Deng","orcid":"https://orcid.org/0000-0003-2869-1619"},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lei Deng","raw_affiliation_strings":["School of Software, Central South University, Changsha, China","School of Software, Central South University, Changsha, China#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Software, Central South University, Changsha, China","institution_ids":["https://openalex.org/I139660479"]},{"raw_affiliation_string":"School of Software, Central South University, Changsha, China#TAB#","institution_ids":["https://openalex.org/I139660479"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100332258","display_name":"Zhigang Chen","orcid":"https://orcid.org/0000-0002-4437-4077"},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhigang Chen","raw_affiliation_strings":["School of Software, Central South University, Changsha, China","School of Software, Central South University, Changsha, China#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Software, Central South University, Changsha, China","institution_ids":["https://openalex.org/I139660479"]},{"raw_affiliation_string":"School of Software, Central South University, Changsha, China#TAB#","institution_ids":["https://openalex.org/I139660479"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I139660479"],"apc_list":{"value":2645,"currency":"USD","value_usd":2645},"apc_paid":null,"fwci":2.2015,"has_fulltext":false,"cited_by_count":27,"citation_normalized_percentile":{"value":0.87924467,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"12","issue":"4","first_page":"902","last_page":"913"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9987000226974487,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9987000226974487,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.9986000061035156,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9979000091552734,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gene-ontology","display_name":"Gene ontology","score":0.7821915149688721},{"id":"https://openalex.org/keywords/structural-genomics","display_name":"Structural genomics","score":0.7033126950263977},{"id":"https://openalex.org/keywords/domain","display_name":"Domain (mathematical analysis)","score":0.6722728610038757},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.620198667049408},{"id":"https://openalex.org/keywords/annotation","display_name":"Annotation","score":0.6166436672210693},{"id":"https://openalex.org/keywords/ontology","display_name":"Ontology","score":0.5945666432380676},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5591055154800415},{"id":"https://openalex.org/keywords/protein-domain","display_name":"Protein domain","score":0.5163977742195129},{"id":"https://openalex.org/keywords/function","display_name":"Function (biology)","score":0.5078359246253967},{"id":"https://openalex.org/keywords/scope","display_name":"Scope (computer science)","score":0.48584529757499695},{"id":"https://openalex.org/keywords/protein-function-prediction","display_name":"Protein function prediction","score":0.4856070876121521},{"id":"https://openalex.org/keywords/protein-structure-database","display_name":"Protein structure database","score":0.44986438751220703},{"id":"https://openalex.org/keywords/structural-classification-of-proteins-database","display_name":"Structural Classification of Proteins database","score":0.44486433267593384},{"id":"https://openalex.org/keywords/functional-genomics","display_name":"Functional genomics","score":0.4313738942146301},{"id":"https://openalex.org/keywords/protein-structure","display_name":"Protein structure","score":0.3677358031272888},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.36253494024276733},{"id":"https://openalex.org/keywords/genomics","display_name":"Genomics","score":0.3252105712890625},{"id":"https://openalex.org/keywords/protein-function","display_name":"Protein function","score":0.3235667049884796},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.26664119958877563},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.2638879418373108},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.25002479553222656},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.14611566066741943},{"id":"https://openalex.org/keywords/genome","display_name":"Genome","score":0.13254237174987793},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.12268650531768799},{"id":"https://openalex.org/keywords/sequence-database","display_name":"Sequence database","score":0.08549961447715759}],"concepts":[{"id":"https://openalex.org/C2987395477","wikidata":"https://www.wikidata.org/wiki/Q135085","display_name":"Gene ontology","level":4,"score":0.7821915149688721},{"id":"https://openalex.org/C192772702","wikidata":"https://www.wikidata.org/wiki/Q2583975","display_name":"Structural genomics","level":3,"score":0.7033126950263977},{"id":"https://openalex.org/C36503486","wikidata":"https://www.wikidata.org/wiki/Q11235244","display_name":"Domain (mathematical analysis)","level":2,"score":0.6722728610038757},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.620198667049408},{"id":"https://openalex.org/C2776321320","wikidata":"https://www.wikidata.org/wiki/Q857525","display_name":"Annotation","level":2,"score":0.6166436672210693},{"id":"https://openalex.org/C25810664","wikidata":"https://www.wikidata.org/wiki/Q44325","display_name":"Ontology","level":2,"score":0.5945666432380676},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5591055154800415},{"id":"https://openalex.org/C144292202","wikidata":"https://www.wikidata.org/wiki/Q898273","display_name":"Protein domain","level":3,"score":0.5163977742195129},{"id":"https://openalex.org/C14036430","wikidata":"https://www.wikidata.org/wiki/Q3736076","display_name":"Function (biology)","level":2,"score":0.5078359246253967},{"id":"https://openalex.org/C2778012447","wikidata":"https://www.wikidata.org/wiki/Q1034415","display_name":"Scope (computer science)","level":2,"score":0.48584529757499695},{"id":"https://openalex.org/C207060522","wikidata":"https://www.wikidata.org/wiki/Q7251473","display_name":"Protein function prediction","level":4,"score":0.4856070876121521},{"id":"https://openalex.org/C136475424","wikidata":"https://www.wikidata.org/wiki/Q7251500","display_name":"Protein structure database","level":4,"score":0.44986438751220703},{"id":"https://openalex.org/C58773245","wikidata":"https://www.wikidata.org/wiki/Q4832556","display_name":"Structural Classification of Proteins database","level":3,"score":0.44486433267593384},{"id":"https://openalex.org/C161078062","wikidata":"https://www.wikidata.org/wiki/Q1068690","display_name":"Functional genomics","level":5,"score":0.4313738942146301},{"id":"https://openalex.org/C47701112","wikidata":"https://www.wikidata.org/wiki/Q735188","display_name":"Protein structure","level":2,"score":0.3677358031272888},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.36253494024276733},{"id":"https://openalex.org/C189206191","wikidata":"https://www.wikidata.org/wiki/Q222046","display_name":"Genomics","level":4,"score":0.3252105712890625},{"id":"https://openalex.org/C2986374874","wikidata":"https://www.wikidata.org/wiki/Q8054","display_name":"Protein function","level":3,"score":0.3235667049884796},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.26664119958877563},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.2638879418373108},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.25002479553222656},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.14611566066741943},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.13254237174987793},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.12268650531768799},{"id":"https://openalex.org/C41584329","wikidata":"https://www.wikidata.org/wiki/Q175902","display_name":"Sequence database","level":3,"score":0.08549961447715759},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C134306372","wikidata":"https://www.wikidata.org/wiki/Q7754","display_name":"Mathematical analysis","level":1,"score":0.0},{"id":"https://openalex.org/C111472728","wikidata":"https://www.wikidata.org/wiki/Q9471","display_name":"Epistemology","level":1,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D001499","descriptor_name":"Bayes Theorem","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001499","descriptor_name":"Bayes Theorem","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001499","descriptor_name":"Bayes Theorem","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D017434","descriptor_name":"Protein Structure, Tertiary","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017434","descriptor_name":"Protein Structure, Tertiary","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017434","descriptor_name":"Protein Structure, Tertiary","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D058977","descriptor_name":"Molecular Sequence Annotation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D058977","descriptor_name":"Molecular Sequence Annotation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D058977","descriptor_name":"Molecular Sequence Annotation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1109/tcbb.2015.2389213","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tcbb.2015.2389213","pdf_url":null,"source":{"id":"https://openalex.org/S36029991","display_name":"IEEE Transactions on Computational Biology and Bioinformatics","issn_l":"1545-5963","issn":["1545-5963","1557-9964","2374-0043","2998-4165"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE/ACM Transactions on Computational Biology and Bioinformatics","raw_type":"journal-article"},{"id":"pmid:26357331","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26357331","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE/ACM transactions on computational biology and bioinformatics","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Life in Land","id":"https://metadata.un.org/sdg/15","score":0.4699999988079071}],"awards":[{"id":"https://openalex.org/G3771677608","display_name":null,"funder_award_id":"61309010","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G4230020160","display_name":"\u673a\u4f1a\u7f51\u7edc\u79fb\u52a8\u89c4\u5f8b\u81ea\u9002\u5e94\u7684\u534f\u540c\u4f20\u8f93\u673a\u5236\u53ca\u6280\u672f\u7814\u7a76","funder_award_id":"61379057","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":51,"referenced_works":["https://openalex.org/W24553703","https://openalex.org/W1618905105","https://openalex.org/W1817561967","https://openalex.org/W1933777541","https://openalex.org/W1971650367","https://openalex.org/W1993279060","https://openalex.org/W1994025789","https://openalex.org/W2005162839","https://openalex.org/W2022366078","https://openalex.org/W2026653305","https://openalex.org/W2039473152","https://openalex.org/W2055522016","https://openalex.org/W2056983531","https://openalex.org/W2078483536","https://openalex.org/W2085277871","https://openalex.org/W2086130370","https://openalex.org/W2088038235","https://openalex.org/W2090146405","https://openalex.org/W2093282128","https://openalex.org/W2098425296","https://openalex.org/W2102424043","https://openalex.org/W2103017472","https://openalex.org/W2107903949","https://openalex.org/W2108491719","https://openalex.org/W2115138247","https://openalex.org/W2117077088","https://openalex.org/W2117486996","https://openalex.org/W2119331235","https://openalex.org/W2119821739","https://openalex.org/W2122936417","https://openalex.org/W2124445678","https://openalex.org/W2129448726","https://openalex.org/W2132122858","https://openalex.org/W2141885858","https://openalex.org/W2144363281","https://openalex.org/W2151831732","https://openalex.org/W2152705149","https://openalex.org/W2153187042","https://openalex.org/W2153635508","https://openalex.org/W2157210912","https://openalex.org/W2158714788","https://openalex.org/W2161072217","https://openalex.org/W2161241566","https://openalex.org/W2163584414","https://openalex.org/W2166699767","https://openalex.org/W2768149277","https://openalex.org/W4210400672","https://openalex.org/W4230932396","https://openalex.org/W4235848672","https://openalex.org/W4239510810","https://openalex.org/W6636501900"],"related_works":["https://openalex.org/W158041880","https://openalex.org/W2170471837","https://openalex.org/W2125494000","https://openalex.org/W1983625232","https://openalex.org/W2118652015","https://openalex.org/W1955025754","https://openalex.org/W2470147982","https://openalex.org/W1914481269","https://openalex.org/W1917981667","https://openalex.org/W2065993463"],"abstract_inverted_index":{"Structural":[0,57],"domains":[1,107,129,171],"are":[2,36],"evolutionary":[3],"and":[4,9,16,91,135,150,176],"functional":[5,17,34],"units":[6],"of":[7,21,114,125,174],"proteins":[8,41],"play":[10],"a":[11,61,96,112,146],"critical":[12],"role":[13],"in":[14,130,172],"comparative":[15],"genomics.":[18],"Computational":[19],"assignment":[20],"domain":[22,116],"function":[23,166],"with":[24,95,108],"high":[25],"reliability":[26],"is":[27],"essential":[28],"for":[29,68,169],"understanding":[30],"whole-protein":[31],"functions.":[32,140],"However,":[33],"annotations":[35],"conventionally":[37],"assigned":[38],"onto":[39],"full-length":[40],"rather":[42],"than":[43],"associating":[44],"specific":[45],"functions":[46,67],"to":[47,65,105,117],"the":[48,126,164],"individual":[49],"structural":[50,70,170],"domains.":[51,71],"In":[52],"this":[53],"article,":[54],"we":[55,110],"present":[56],"Domain":[58],"Annotation":[59],"(SDA),":[60],"novel":[62],"computational":[63],"approach":[64],"predict":[66],"SCOP":[69,106,115],"The":[72],"SDA":[73,144,161],"method":[74],"integrates":[75],"heterogeneous":[76],"information":[77],"sources,":[78],"including":[79],"structure":[80],"alignment":[81],"based":[82],"protein-SCOP":[83],"mapping":[84,87],"features,":[85,94],"InterPro2GO":[86],"information,":[88],"PSSM":[89],"Profiles,":[90],"sequence":[92],"neighborhood":[93],"Bayesian":[97],"network.":[98],"By":[99],"large-scale":[100],"annotating":[101],"Gene":[102,118,138],"Ontology":[103,119,139],"terms":[104,173],"SDA,":[109],"obtained":[111],"database":[113],"mappings,":[120],"which":[121],"contains":[122],"~162,000":[123],"out":[124],"approximately":[127],"166,900":[128],"SCOPe":[131],"2.03":[132],"(>97":[133],"percent)":[134],"their":[136],"predicted":[137],"We":[141],"have":[142],"benchmarked":[143],"using":[145],"single-domain":[147],"protein":[148],"dataset":[149,153],"an":[151],"independent":[152],"from":[154],"different":[155],"species.":[156],"Comparative":[157],"studies":[158],"show":[159],"that":[160],"significantly":[162],"outperforms":[163],"existing":[165],"prediction":[167],"methods":[168],"coverage":[175],"maximum":[177],"F-measure.":[178]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":6},{"year":2018,"cited_by_count":8},{"year":2017,"cited_by_count":6},{"year":2016,"cited_by_count":2}],"updated_date":"2026-08-21T09:56:20.448147","created_date":"2025-10-10T00:00:00"}