{"id":"https://openalex.org/W2054673300","doi":"https://doi.org/10.1109/tcbb.2014.2355218","title":"Predicting the Pro-Longevity or Anti-Longevity Effect of Model Organism Genes with New Hierarchical Feature Selection Methods","display_name":"Predicting the Pro-Longevity or Anti-Longevity Effect of Model Organism Genes with New Hierarchical Feature Selection Methods","publication_year":2014,"publication_date":"2014-09-16","ids":{"openalex":"https://openalex.org/W2054673300","doi":"https://doi.org/10.1109/tcbb.2014.2355218","mag":"2054673300","pmid":"https://pubmed.ncbi.nlm.nih.gov/26357215"},"language":"en","primary_location":{"id":"doi:10.1109/tcbb.2014.2355218","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tcbb.2014.2355218","pdf_url":null,"source":{"id":"https://openalex.org/S36029991","display_name":"IEEE Transactions on Computational Biology and Bioinformatics","issn_l":"1545-5963","issn":["1545-5963","1557-9964","2374-0043","2998-4165"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE/ACM Transactions on Computational Biology and Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5057894585","display_name":"Cen Wan","orcid":"https://orcid.org/0000-0002-3872-0340"},"institutions":[{"id":"https://openalex.org/I20581793","display_name":"University of Kent","ror":"https://ror.org/00xkeyj56","country_code":"GB","type":"education","lineage":["https://openalex.org/I20581793"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Cen Wan","raw_affiliation_strings":["School of Computing, University of Kent, Canterbury, United Kingdom","School of Computing - University of Kent, Canterbury, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Computing, University of Kent, Canterbury, United Kingdom","institution_ids":["https://openalex.org/I20581793"]},{"raw_affiliation_string":"School of Computing - University of Kent, Canterbury, United Kingdom","institution_ids":["https://openalex.org/I20581793"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087201377","display_name":"Alex A. Freitas","orcid":"https://orcid.org/0000-0001-9825-4700"},"institutions":[{"id":"https://openalex.org/I20581793","display_name":"University of Kent","ror":"https://ror.org/00xkeyj56","country_code":"GB","type":"education","lineage":["https://openalex.org/I20581793"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Alex A. Freitas","raw_affiliation_strings":["School of Computing, University of Kent, Canterbury, United Kingdom","School of Computing - University of Kent, Canterbury, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Computing, University of Kent, Canterbury, United Kingdom","institution_ids":["https://openalex.org/I20581793"]},{"raw_affiliation_string":"School of Computing - University of Kent, Canterbury, United Kingdom","institution_ids":["https://openalex.org/I20581793"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5054858013","display_name":"Jo\u00e3o Pedro de Magalh\u00e3es","orcid":"https://orcid.org/0000-0002-6363-2465"},"institutions":[{"id":"https://openalex.org/I146655781","display_name":"University of Liverpool","ror":"https://ror.org/04xs57h96","country_code":"GB","type":"education","lineage":["https://openalex.org/I146655781"]},{"id":"https://openalex.org/I4210151791","display_name":"Genomics (United Kingdom)","ror":"https://ror.org/053a6xa29","country_code":"GB","type":"company","lineage":["https://openalex.org/I4210151791"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Joao Pedro de Magalhaes","raw_affiliation_strings":["Integrative Genomics of Ageing Group, University of Liverpool, Liverpool, United Kingdom","[Integrative Genomics of Ageing Group, University of Liverpool, Liverpool, United Kingdom]"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Integrative Genomics of Ageing Group, University of Liverpool, Liverpool, United Kingdom","institution_ids":["https://openalex.org/I146655781","https://openalex.org/I4210151791"]},{"raw_affiliation_string":"[Integrative Genomics of Ageing Group, University of Liverpool, Liverpool, United Kingdom]","institution_ids":["https://openalex.org/I146655781"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":2645,"currency":"USD","value_usd":2645},"apc_paid":null,"fwci":1.0504,"has_fulltext":false,"cited_by_count":46,"citation_normalized_percentile":{"value":0.70601852,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":99},"biblio":{"volume":"12","issue":"2","first_page":"262","last_page":"275"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10676","display_name":"Genetics, Aging, and Longevity in Model Organisms","score":0.9983999729156494,"subfield":{"id":"https://openalex.org/subfields/1302","display_name":"Aging"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10676","display_name":"Genetics, Aging, and Longevity in Model Organisms","score":0.9983999729156494,"subfield":{"id":"https://openalex.org/subfields/1302","display_name":"Aging"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9958000183105469,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9818999767303467,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/feature-selection","display_name":"Feature selection","score":0.6606959104537964},{"id":"https://openalex.org/keywords/naive-bayes-classifier","display_name":"Naive Bayes classifier","score":0.5852879285812378},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.5504348278045654},{"id":"https://openalex.org/keywords/bayes-theorem","display_name":"Bayes' theorem","score":0.5501167178153992},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.5458479523658752},{"id":"https://openalex.org/keywords/longevity","display_name":"Longevity","score":0.5322456359863281},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.49622613191604614},{"id":"https://openalex.org/keywords/feature","display_name":"Feature (linguistics)","score":0.4540402293205261},{"id":"https://openalex.org/keywords/selection","display_name":"Selection (genetic algorithm)","score":0.4131205677986145},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.3748456835746765},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.29115504026412964},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.15268230438232422},{"id":"https://openalex.org/keywords/bayesian-probability","display_name":"Bayesian probability","score":0.12742063403129578},{"id":"https://openalex.org/keywords/support-vector-machine","display_name":"Support vector machine","score":0.10812357068061829}],"concepts":[{"id":"https://openalex.org/C148483581","wikidata":"https://www.wikidata.org/wiki/Q446488","display_name":"Feature selection","level":2,"score":0.6606959104537964},{"id":"https://openalex.org/C52001869","wikidata":"https://www.wikidata.org/wiki/Q812530","display_name":"Naive Bayes classifier","level":3,"score":0.5852879285812378},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.5504348278045654},{"id":"https://openalex.org/C207201462","wikidata":"https://www.wikidata.org/wiki/Q182505","display_name":"Bayes' theorem","level":3,"score":0.5501167178153992},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.5458479523658752},{"id":"https://openalex.org/C2776759703","wikidata":"https://www.wikidata.org/wiki/Q1066907","display_name":"Longevity","level":2,"score":0.5322456359863281},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.49622613191604614},{"id":"https://openalex.org/C2776401178","wikidata":"https://www.wikidata.org/wiki/Q12050496","display_name":"Feature (linguistics)","level":2,"score":0.4540402293205261},{"id":"https://openalex.org/C81917197","wikidata":"https://www.wikidata.org/wiki/Q628760","display_name":"Selection (genetic algorithm)","level":2,"score":0.4131205677986145},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.3748456835746765},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.29115504026412964},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.15268230438232422},{"id":"https://openalex.org/C107673813","wikidata":"https://www.wikidata.org/wiki/Q812534","display_name":"Bayesian probability","level":2,"score":0.12742063403129578},{"id":"https://openalex.org/C12267149","wikidata":"https://www.wikidata.org/wiki/Q282453","display_name":"Support vector machine","level":2,"score":0.10812357068061829},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001499","descriptor_name":"Bayes Theorem","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001499","descriptor_name":"Bayes Theorem","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001499","descriptor_name":"Bayes Theorem","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004331","descriptor_name":"Drosophila melanogaster","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004331","descriptor_name":"Drosophila melanogaster","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004331","descriptor_name":"Drosophila melanogaster","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D008957","descriptor_name":"Models, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008957","descriptor_name":"Models, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008957","descriptor_name":"Models, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012441","descriptor_name":"Saccharomyces cerevisiae","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012441","descriptor_name":"Saccharomyces cerevisiae","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012441","descriptor_name":"Saccharomyces cerevisiae","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D016922","descriptor_name":"Cellular Senescence","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D016922","descriptor_name":"Cellular Senescence","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D016922","descriptor_name":"Cellular Senescence","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017173","descriptor_name":"Caenorhabditis elegans","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017173","descriptor_name":"Caenorhabditis elegans","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017173","descriptor_name":"Caenorhabditis elegans","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057225","descriptor_name":"Data Mining","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D057225","descriptor_name":"Data Mining","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D057225","descriptor_name":"Data Mining","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D063990","descriptor_name":"Gene Ontology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D063990","descriptor_name":"Gene Ontology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D063990","descriptor_name":"Gene Ontology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1109/tcbb.2014.2355218","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tcbb.2014.2355218","pdf_url":null,"source":{"id":"https://openalex.org/S36029991","display_name":"IEEE Transactions on Computational Biology and Bioinformatics","issn_l":"1545-5963","issn":["1545-5963","1557-9964","2374-0043","2998-4165"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE/ACM Transactions on Computational Biology and Bioinformatics","raw_type":"journal-article"},{"id":"pmid:26357215","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26357215","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE/ACM transactions on computational biology and bioinformatics","raw_type":"Journal Article"},{"id":"pmh:oai:kar.kent.ac.uk:47996","is_oa":false,"landing_page_url":"https://doi.org/10.1109/TCBB.2014.2355218>)","pdf_url":null,"source":{"id":"https://openalex.org/S4377196264","display_name":"Kent Academic Repository (University of Kent)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I20581793","host_organization_name":"University of Kent","host_organization_lineage":["https://openalex.org/I20581793"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.700.1418","is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.700.1418","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://pcwww.liv.ac.uk/%7Eaging/ieee15_inpress.pdf","raw_type":"text"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1242411389","display_name":null,"funder_award_id":"EP/E049419/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G313042574","display_name":null,"funder_award_id":"EP/E053505/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G3908668408","display_name":null,"funder_award_id":"ME050495MES","funder_id":"https://openalex.org/F4320311904","funder_display_name":"Wellcome Trust"},{"id":"https://openalex.org/G4863817842","display_name":"CoSMoS: Complex Systems Modelling and Simulation","funder_award_id":"EP/E049419/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G5748799696","display_name":"CoSMoS: Complex Systems Modelling and Simulation","funder_award_id":"EP/E053505/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"}],"funders":[{"id":"https://openalex.org/F4320311904","display_name":"Wellcome Trust","ror":"https://ror.org/029chgv08"},{"id":"https://openalex.org/F4320334627","display_name":"Engineering and Physical Sciences Research Council","ror":"https://ror.org/0439y7842"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":43,"referenced_works":["https://openalex.org/W17986227","https://openalex.org/W141379870","https://openalex.org/W608314793","https://openalex.org/W1565746575","https://openalex.org/W1570448133","https://openalex.org/W1570713908","https://openalex.org/W1590183771","https://openalex.org/W1644997609","https://openalex.org/W1658682427","https://openalex.org/W1971784203","https://openalex.org/W1994166779","https://openalex.org/W1994309289","https://openalex.org/W2004131797","https://openalex.org/W2005861721","https://openalex.org/W2007711341","https://openalex.org/W2058414375","https://openalex.org/W2058484936","https://openalex.org/W2070299975","https://openalex.org/W2075278115","https://openalex.org/W2091299760","https://openalex.org/W2096166399","https://openalex.org/W2100758570","https://openalex.org/W2103017472","https://openalex.org/W2103914828","https://openalex.org/W2108687351","https://openalex.org/W2118957830","https://openalex.org/W2122111042","https://openalex.org/W2123336312","https://openalex.org/W2123703699","https://openalex.org/W2126525177","https://openalex.org/W2135618462","https://openalex.org/W2140825458","https://openalex.org/W2141013052","https://openalex.org/W2147375971","https://openalex.org/W2150766729","https://openalex.org/W2151807108","https://openalex.org/W2911678770","https://openalex.org/W2966207845","https://openalex.org/W2993222596","https://openalex.org/W3099503819","https://openalex.org/W4235072768","https://openalex.org/W4245055982","https://openalex.org/W6600721486"],"related_works":["https://openalex.org/W1585830474","https://openalex.org/W4315797749","https://openalex.org/W2393707090","https://openalex.org/W2188080485","https://openalex.org/W2539138474","https://openalex.org/W2537862391","https://openalex.org/W2417174640","https://openalex.org/W4386564352","https://openalex.org/W4378417285","https://openalex.org/W2952668426"],"abstract_inverted_index":{"Ageing":[0],"is":[1,8,31,104],"a":[2,188],"highly":[3],"complex":[4],"biological":[5,185],"process":[6],"that":[7,39,49,105,150],"still":[9],"poorly":[10],"understood.":[11],"With":[12],"the":[13,21,26,65,99,111,122,126,170,184],"growing":[14],"amount":[15],"of":[16,28,68,98,113,125,187,190],"ageing-related":[17,75],"data":[18,35,69,76],"available":[19],"on":[20],"web,":[22],"in":[23,41,110,118,200],"particular":[24],"concerning":[25],"genetics":[27],"ageing,":[29],"it":[30],"timely":[32],"to":[33,38,43,45,74,120,137],"apply":[34,72],"mining":[36,70],"methods":[37,63,103],"data,":[40],"order":[42,119],"try":[44],"discover":[46],"novel":[47,96],"patterns":[48],"may":[50],"assist":[51],"ageing":[52],"research.":[53],"In":[54],"this":[55],"work,":[56],"we":[57],"introduce":[58],"new":[59],"hierarchical":[60,108,152],"feature":[61,101,153,173],"selection":[62,102,154],"for":[64],"classification":[66],"task":[67],"and":[71,90,129,162,177],"them":[73],"from":[77],"four":[78],"model":[79,139],"organisms:":[80],"Caenorhabditis":[81],"elegans":[82],"(worm),":[83],"Saccharomyces":[84],"cerevisiae":[85],"(yeast),":[86],"Drosophila":[87],"melanogaster":[88],"(fly),":[89],"Mus":[91],"musculus":[92],"(mouse).":[93],"The":[94,147],"main":[95],"aspect":[97],"proposed":[100],"they":[106],"exploit":[107],"relationships":[109],"set":[112],"features":[114],"(Gene":[115],"Ontology":[116,192],"terms)":[117],"improve":[121],"predictive":[123,167],"accuracy":[124,168],"Na\u00efve":[127,160,175],"Bayes":[128,161,176],"1-Nearest":[130],"Neighbour":[131],"(1-NN)":[132],"classifiers,":[133,164,179],"which":[134],"are":[135],"used":[136,157],"classify":[138],"organisms'":[140],"genes":[141],"into":[142],"pro-longevity":[143],"or":[144],"anti-longevity":[145],"genes.":[146],"results":[148],"show":[149],"our":[151,198,201],"methods,":[155],"when":[156],"together":[158],"with":[159],"1-NN":[163,178],"obtain":[165],"higher":[166],"than":[169],"standard":[171],"(without":[172],"selection)":[174],"respectively.":[180],"We":[181],"also":[182],"discuss":[183],"relevance":[186],"number":[189],"Gene":[191],"terms":[193],"very":[194],"frequently":[195],"selected":[196],"by":[197],"algorithms":[199],"datasets.":[202]},"counts_by_year":[{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":9},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":8},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":3}],"updated_date":"2026-08-26T07:47:46.906454","created_date":"2025-10-10T00:00:00"}