{"id":"https://openalex.org/W1991293964","doi":"https://doi.org/10.1109/tcbb.2014.2338319","title":"On Representing Protein Folding Patterns Using Non-Linear Parametric Curves","display_name":"On Representing Protein Folding Patterns Using Non-Linear Parametric Curves","publication_year":2014,"publication_date":"2014-07-11","ids":{"openalex":"https://openalex.org/W1991293964","doi":"https://doi.org/10.1109/tcbb.2014.2338319","mag":"1991293964"},"language":"en","primary_location":{"id":"doi:10.1109/tcbb.2014.2338319","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tcbb.2014.2338319","pdf_url":null,"source":{"id":"https://openalex.org/S36029991","display_name":"IEEE/ACM Transactions on Computational Biology and Bioinformatics","issn_l":"1545-5963","issn":["1545-5963","1557-9964","2374-0043"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE/ACM Transactions on Computational Biology and Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5037254330","display_name":"Parthan Kasarapu","orcid":"https://orcid.org/0000-0002-8317-3649"},"institutions":[{"id":"https://openalex.org/I56590836","display_name":"Monash University","ror":"https://ror.org/02bfwt286","country_code":"AU","type":"education","lineage":["https://openalex.org/I56590836"]}],"countries":["AU"],"is_corresponding":true,"raw_author_name":"Parthan Kasarapu","raw_affiliation_strings":["Clayton School of Information Technology, Monash University, VIC, Australia","The Clayton School of Information Technology, Monash University, VIC, Australia#TAB#"],"affiliations":[{"raw_affiliation_string":"Clayton School of Information Technology, Monash University, VIC, Australia","institution_ids":["https://openalex.org/I56590836"]},{"raw_affiliation_string":"The Clayton School of Information Technology, Monash University, VIC, Australia#TAB#","institution_ids":["https://openalex.org/I56590836"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083095334","display_name":"Mar\u00eda Garc\u00eda de la Banda","orcid":"https://orcid.org/0000-0002-6666-514X"},"institutions":[{"id":"https://openalex.org/I56590836","display_name":"Monash University","ror":"https://ror.org/02bfwt286","country_code":"AU","type":"education","lineage":["https://openalex.org/I56590836"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Maria Garcia de la Banda","raw_affiliation_strings":["Clayton School of Information Technology, Monash University, VIC, Australia","The Clayton School of Information Technology, Monash University, VIC, Australia#TAB#"],"affiliations":[{"raw_affiliation_string":"Clayton School of Information Technology, Monash University, VIC, Australia","institution_ids":["https://openalex.org/I56590836"]},{"raw_affiliation_string":"The Clayton School of Information Technology, Monash University, VIC, Australia#TAB#","institution_ids":["https://openalex.org/I56590836"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5081792355","display_name":"Arun S. Konagurthu","orcid":"https://orcid.org/0000-0002-1610-8329"},"institutions":[{"id":"https://openalex.org/I56590836","display_name":"Monash University","ror":"https://ror.org/02bfwt286","country_code":"AU","type":"education","lineage":["https://openalex.org/I56590836"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Arun S. Konagurthu","raw_affiliation_strings":["Clayton School of Information Technology, Monash University, VIC, Australia","The Clayton School of Information Technology, Monash University, VIC, Australia#TAB#"],"affiliations":[{"raw_affiliation_string":"Clayton School of Information Technology, Monash University, VIC, Australia","institution_ids":["https://openalex.org/I56590836"]},{"raw_affiliation_string":"The Clayton School of Information Technology, Monash University, VIC, Australia#TAB#","institution_ids":["https://openalex.org/I56590836"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5037254330"],"corresponding_institution_ids":["https://openalex.org/I56590836"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.06018798,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":94},"biblio":{"volume":"11","issue":"6","first_page":"1218","last_page":"1228"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.9977999925613403,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.9977999925613403,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.9222999811172485,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11162","display_name":"Enzyme Structure and Function","score":0.9027000069618225,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/folding","display_name":"Folding (DSP implementation)","score":0.6279534101486206},{"id":"https://openalex.org/keywords/parametric-statistics","display_name":"Parametric statistics","score":0.6206014156341553},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6169265508651733},{"id":"https://openalex.org/keywords/abstraction","display_name":"Abstraction","score":0.6114168763160706},{"id":"https://openalex.org/keywords/protein-folding","display_name":"Protein folding","score":0.5448557734489441},{"id":"https://openalex.org/keywords/set","display_name":"Set (abstract data type)","score":0.5297504663467407},{"id":"https://openalex.org/keywords/inference","display_name":"Inference","score":0.5296592116355896},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.4733198583126068},{"id":"https://openalex.org/keywords/theoretical-computer-science","display_name":"Theoretical computer science","score":0.3517780601978302},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.262842059135437},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.20457413792610168},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.08475375175476074},{"id":"https://openalex.org/keywords/statistics","display_name":"Statistics","score":0.08237802982330322}],"concepts":[{"id":"https://openalex.org/C2776545253","wikidata":"https://www.wikidata.org/wiki/Q5464292","display_name":"Folding (DSP implementation)","level":2,"score":0.6279534101486206},{"id":"https://openalex.org/C117251300","wikidata":"https://www.wikidata.org/wiki/Q1849855","display_name":"Parametric statistics","level":2,"score":0.6206014156341553},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6169265508651733},{"id":"https://openalex.org/C124304363","wikidata":"https://www.wikidata.org/wiki/Q673661","display_name":"Abstraction","level":2,"score":0.6114168763160706},{"id":"https://openalex.org/C204328495","wikidata":"https://www.wikidata.org/wiki/Q847556","display_name":"Protein folding","level":2,"score":0.5448557734489441},{"id":"https://openalex.org/C177264268","wikidata":"https://www.wikidata.org/wiki/Q1514741","display_name":"Set (abstract data type)","level":2,"score":0.5297504663467407},{"id":"https://openalex.org/C2776214188","wikidata":"https://www.wikidata.org/wiki/Q408386","display_name":"Inference","level":2,"score":0.5296592116355896},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.4733198583126068},{"id":"https://openalex.org/C80444323","wikidata":"https://www.wikidata.org/wiki/Q2878974","display_name":"Theoretical computer science","level":1,"score":0.3517780601978302},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.262842059135437},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.20457413792610168},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.08475375175476074},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.08237802982330322},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C111472728","wikidata":"https://www.wikidata.org/wiki/Q9471","display_name":"Epistemology","level":1,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C119599485","wikidata":"https://www.wikidata.org/wiki/Q43035","display_name":"Electrical engineering","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/tcbb.2014.2338319","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tcbb.2014.2338319","pdf_url":null,"source":{"id":"https://openalex.org/S36029991","display_name":"IEEE/ACM Transactions on Computational Biology and Bioinformatics","issn_l":"1545-5963","issn":["1545-5963","1557-9964","2374-0043"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE/ACM Transactions on Computational Biology and Bioinformatics","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":23,"referenced_works":["https://openalex.org/W170307911","https://openalex.org/W196385585","https://openalex.org/W1568771894","https://openalex.org/W1967538863","https://openalex.org/W1995875735","https://openalex.org/W1996945721","https://openalex.org/W2008708467","https://openalex.org/W2019949712","https://openalex.org/W2021115755","https://openalex.org/W2022058405","https://openalex.org/W2030868839","https://openalex.org/W2066805041","https://openalex.org/W2074362388","https://openalex.org/W2085277871","https://openalex.org/W2102245393","https://openalex.org/W2110381504","https://openalex.org/W2122853741","https://openalex.org/W2127793522","https://openalex.org/W2128777897","https://openalex.org/W2131146043","https://openalex.org/W2139774535","https://openalex.org/W2142749069","https://openalex.org/W2151785844"],"related_works":["https://openalex.org/W2260493136","https://openalex.org/W2113188411","https://openalex.org/W2976965029","https://openalex.org/W2382178265","https://openalex.org/W2055827177","https://openalex.org/W2072666835","https://openalex.org/W4248706500","https://openalex.org/W2939859775","https://openalex.org/W2103379028","https://openalex.org/W2467603891"],"abstract_inverted_index":{"Proteins":[0],"fold":[1],"into":[2],"complex":[3],"three-dimensional":[4],"shapes.":[5],"Simplified":[6],"representations":[7],"of":[8,39,51,56,68,76,83,100,105,125,135,145],"their":[9,31],"shapes":[10],"are":[11],"central":[12],"to":[13,23,60,92,112,139],"rationalise,":[14],"compare,":[15],"classify,":[16],"and":[17,37,64,79,108,120,142],"interpret":[18],"protein":[19,25,69,95,146],"structures.":[20],"Traditional":[21],"methods":[22],"abstract":[24],"folding":[26,70,147],"patterns":[27,71,148],"rely":[28],"on":[29,88,149],"representing":[30],"standard":[32],"secondary":[33],"structural":[34,52,77,84],"elements":[35],"(helices":[36],"strands":[38],"sheet)":[40],"using":[41],"line":[42],"segments.":[43],"This":[44],"results":[45],"in":[46],"ignoring":[47],"a":[48,89,94,97,150],"significant":[49],"proportion":[50],"information.":[53,85],"The":[54],"motivation":[55],"this":[57,113],"research":[58],"is":[59,115],"derive":[61],"mathematically":[62],"rigorous":[63],"biologically":[65],"meaningful":[66],"abstractions":[67],"that":[72],"maximize":[73],"the":[74,81,122,133],"economy":[75],"description":[78],"minimize":[80],"loss":[82],"We":[86,131],"report":[87],"novel":[90],"method":[91],"describe":[93],"as":[96],"non-overlapping":[98],"set":[99],"parametric":[101],"three":[102],"dimensional":[103],"curves":[104],"varying":[106],"length":[107,128],"complexity.":[109],"Our":[110],"approach":[111],"problem":[114],"supported":[116],"by":[117],"information":[118],"theory":[119],"uses":[121],"statistical":[123],"framework":[124],"minimum":[126],"message":[127],"(MML)":[129],"inference.":[130],"demonstrate":[132],"effectiveness":[134],"our":[136],"non-linear":[137],"abstraction":[138],"support":[140],"efficient":[141],"effective":[143],"comparison":[144],"large":[151],"scale.":[152]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2018,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2016-06-24T00:00:00"}