{"id":"https://openalex.org/W3024099187","doi":"https://doi.org/10.1109/tcad.2020.2994267","title":"DCSA: Distributed Channel-Storage Architecture for Flow-Based Microfluidic Biochips","display_name":"DCSA: Distributed Channel-Storage Architecture for Flow-Based Microfluidic Biochips","publication_year":2020,"publication_date":"2020-05-12","ids":{"openalex":"https://openalex.org/W3024099187","doi":"https://doi.org/10.1109/tcad.2020.2994267","mag":"3024099187"},"language":"en","primary_location":{"id":"doi:10.1109/tcad.2020.2994267","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tcad.2020.2994267","pdf_url":null,"source":{"id":"https://openalex.org/S100835903","display_name":"IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems","issn_l":"0278-0070","issn":["0278-0070","1937-4151"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems","raw_type":"journal-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100631269","display_name":"Chunfeng Liu","orcid":"https://orcid.org/0000-0003-1792-1714"},"institutions":[{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Chunfeng Liu","raw_affiliation_strings":["Chair of Electronic Design Automation, Technical University of Munich, Munich, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chair of Electronic Design Automation, Technical University of Munich, Munich, Germany","institution_ids":["https://openalex.org/I62916508"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017381514","display_name":"Xing Huang","orcid":"https://orcid.org/0000-0002-5396-110X"},"institutions":[{"id":"https://openalex.org/I25846049","display_name":"National Tsing Hua University","ror":"https://ror.org/00zdnkx70","country_code":"TW","type":"education","lineage":["https://openalex.org/I25846049"]},{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE","TW"],"is_corresponding":false,"raw_author_name":"Xing Huang","raw_affiliation_strings":["Chair of Electronic Design Automation, Technical University of Munich, Munich, Germany","Department of Computer Science, National Tsing Hua University, Hsinchu, Taiwan"],"raw_orcid":"https://orcid.org/0000-0002-5396-110X","affiliations":[{"raw_affiliation_string":"Chair of Electronic Design Automation, Technical University of Munich, Munich, Germany","institution_ids":["https://openalex.org/I62916508"]},{"raw_affiliation_string":"Department of Computer Science, National Tsing Hua University, Hsinchu, Taiwan","institution_ids":["https://openalex.org/I25846049"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100451231","display_name":"Bing Li","orcid":"https://orcid.org/0000-0001-9752-7201"},"institutions":[{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Bing Li","raw_affiliation_strings":["Chair of Electronic Design Automation, Technical University of Munich, Munich, Germany"],"raw_orcid":"https://orcid.org/0000-0001-9752-7201","affiliations":[{"raw_affiliation_string":"Chair of Electronic Design Automation, Technical University of Munich, Munich, Germany","institution_ids":["https://openalex.org/I62916508"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058812423","display_name":"Hailong Yao","orcid":"https://orcid.org/0000-0002-8750-3086"},"institutions":[{"id":"https://openalex.org/I25846049","display_name":"National Tsing Hua University","ror":"https://ror.org/00zdnkx70","country_code":"TW","type":"education","lineage":["https://openalex.org/I25846049"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Hailong Yao","raw_affiliation_strings":["Department of Computer Science, National Tsing Hua University, Hsinchu, Taiwan"],"raw_orcid":"https://orcid.org/0000-0002-8750-3086","affiliations":[{"raw_affiliation_string":"Department of Computer Science, National Tsing Hua University, Hsinchu, Taiwan","institution_ids":["https://openalex.org/I25846049"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041645408","display_name":"Paul Pop","orcid":"https://orcid.org/0000-0001-9981-1775"},"institutions":[{"id":"https://openalex.org/I96673099","display_name":"Technical University of Denmark","ror":"https://ror.org/04qtj9h94","country_code":"DK","type":"education","lineage":["https://openalex.org/I96673099"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Paul Pop","raw_affiliation_strings":["Department of Applied Mathematics and Computer Science, Technical University of Denmark, Lyngby, Denmark"],"raw_orcid":"https://orcid.org/0000-0001-9981-1775","affiliations":[{"raw_affiliation_string":"Department of Applied Mathematics and Computer Science, Technical University of Denmark, Lyngby, Denmark","institution_ids":["https://openalex.org/I96673099"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062800747","display_name":"Tsung-Yi Ho","orcid":"https://orcid.org/0000-0001-7348-5625"},"institutions":[{"id":"https://openalex.org/I25846049","display_name":"National Tsing Hua University","ror":"https://ror.org/00zdnkx70","country_code":"TW","type":"education","lineage":["https://openalex.org/I25846049"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Tsung-Yi Ho","raw_affiliation_strings":["Department of Computer Science, National Tsing Hua University, Hsinchu, Taiwan"],"raw_orcid":"https://orcid.org/0000-0001-7348-5625","affiliations":[{"raw_affiliation_string":"Department of Computer Science, National Tsing Hua University, Hsinchu, Taiwan","institution_ids":["https://openalex.org/I25846049"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5017567485","display_name":"Ulf Schlichtmann","orcid":"https://orcid.org/0000-0003-4431-7619"},"institutions":[{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Ulf Schlichtmann","raw_affiliation_strings":["Chair of Electronic Design Automation, Technical University of Munich, Munich, Germany"],"raw_orcid":"https://orcid.org/0000-0003-4431-7619","affiliations":[{"raw_affiliation_string":"Chair of Electronic Design Automation, Technical University of Munich, Munich, Germany","institution_ids":["https://openalex.org/I62916508"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":7,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.9772,"has_fulltext":false,"cited_by_count":29,"citation_normalized_percentile":{"value":0.86532101,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"40","issue":"1","first_page":"115","last_page":"128"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12452","display_name":"Electrowetting and Microfluidic Technologies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T12452","display_name":"Electrowetting and Microfluidic Technologies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10412","display_name":"Microfluidic and Capillary Electrophoresis Applications","score":0.9993000030517578,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11407","display_name":"Innovative Microfluidic and Catalytic Techniques Innovation","score":0.9993000030517578,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/biochip","display_name":"Biochip","score":0.9521842002868652},{"id":"https://openalex.org/keywords/microfluidics","display_name":"Microfluidics","score":0.711268961429596},{"id":"https://openalex.org/keywords/channel","display_name":"Channel (broadcasting)","score":0.5494425296783447},{"id":"https://openalex.org/keywords/architecture","display_name":"Architecture","score":0.5154910683631897},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5142228603363037},{"id":"https://openalex.org/keywords/flow","display_name":"Flow (mathematics)","score":0.45627561211586},{"id":"https://openalex.org/keywords/embedded-system","display_name":"Embedded system","score":0.4067823588848114},{"id":"https://openalex.org/keywords/nanotechnology","display_name":"Nanotechnology","score":0.3920947313308716},{"id":"https://openalex.org/keywords/computer-architecture","display_name":"Computer architecture","score":0.3797352612018585},{"id":"https://openalex.org/keywords/computer-hardware","display_name":"Computer hardware","score":0.36131590604782104},{"id":"https://openalex.org/keywords/process-engineering","display_name":"Process engineering","score":0.32096511125564575},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.27116140723228455},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.2673381268978119},{"id":"https://openalex.org/keywords/computer-network","display_name":"Computer network","score":0.15108808875083923},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.0900440514087677}],"concepts":[{"id":"https://openalex.org/C87892846","wikidata":"https://www.wikidata.org/wiki/Q864256","display_name":"Biochip","level":2,"score":0.9521842002868652},{"id":"https://openalex.org/C8673954","wikidata":"https://www.wikidata.org/wiki/Q138845","display_name":"Microfluidics","level":2,"score":0.711268961429596},{"id":"https://openalex.org/C127162648","wikidata":"https://www.wikidata.org/wiki/Q16858953","display_name":"Channel (broadcasting)","level":2,"score":0.5494425296783447},{"id":"https://openalex.org/C123657996","wikidata":"https://www.wikidata.org/wiki/Q12271","display_name":"Architecture","level":2,"score":0.5154910683631897},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5142228603363037},{"id":"https://openalex.org/C38349280","wikidata":"https://www.wikidata.org/wiki/Q1434290","display_name":"Flow (mathematics)","level":2,"score":0.45627561211586},{"id":"https://openalex.org/C149635348","wikidata":"https://www.wikidata.org/wiki/Q193040","display_name":"Embedded system","level":1,"score":0.4067823588848114},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.3920947313308716},{"id":"https://openalex.org/C118524514","wikidata":"https://www.wikidata.org/wiki/Q173212","display_name":"Computer architecture","level":1,"score":0.3797352612018585},{"id":"https://openalex.org/C9390403","wikidata":"https://www.wikidata.org/wiki/Q3966","display_name":"Computer hardware","level":1,"score":0.36131590604782104},{"id":"https://openalex.org/C21880701","wikidata":"https://www.wikidata.org/wiki/Q2144042","display_name":"Process engineering","level":1,"score":0.32096511125564575},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.27116140723228455},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.2673381268978119},{"id":"https://openalex.org/C31258907","wikidata":"https://www.wikidata.org/wiki/Q1301371","display_name":"Computer network","level":1,"score":0.15108808875083923},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0900440514087677},{"id":"https://openalex.org/C142362112","wikidata":"https://www.wikidata.org/wiki/Q735","display_name":"Art","level":0,"score":0.0},{"id":"https://openalex.org/C57879066","wikidata":"https://www.wikidata.org/wiki/Q41217","display_name":"Mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C153349607","wikidata":"https://www.wikidata.org/wiki/Q36649","display_name":"Visual arts","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1109/tcad.2020.2994267","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tcad.2020.2994267","pdf_url":null,"source":{"id":"https://openalex.org/S100835903","display_name":"IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems","issn_l":"0278-0070","issn":["0278-0070","1937-4151"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems","raw_type":"journal-article"},{"id":"pmh:oai:pure.atira.dk:publications/9fe52325-dfc2-4733-b4ab-074612cb29a2","is_oa":false,"landing_page_url":"https://orbit.dtu.dk/en/publications/9fe52325-dfc2-4733-b4ab-074612cb29a2","pdf_url":null,"source":{"id":"https://openalex.org/S4306400705","display_name":"Technical University of Denmark, DTU Orbit (Technical University of Denmark, DTU)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I96673099","host_organization_name":"Technical University of Denmark","host_organization_lineage":["https://openalex.org/I96673099"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Liu , C , Huang , X , Li , B , Yao , H , Pop , P , Ho , T-Y & Schlichtmann , U 2021 , ' DCSA: Distributed Channel-Storage Architecture for Flow-Based Microfluidic Biochips ' , IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems , vol. 40 , no. 1 , pp. 115-128 . https://doi.org/10.1109/TCAD.2020.2994267","raw_type":"article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G4723301937","display_name":null,"funder_award_id":"n\u00b0 291763","funder_id":"https://openalex.org/F4320333065","funder_display_name":"Seventh Framework Programme"}],"funders":[{"id":"https://openalex.org/F4320320879","display_name":"Deutsche Forschungsgemeinschaft","ror":"https://ror.org/018mejw64"},{"id":"https://openalex.org/F4320333065","display_name":"Seventh Framework Programme","ror":null}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":39,"referenced_works":["https://openalex.org/W404102259","https://openalex.org/W964861289","https://openalex.org/W1480586132","https://openalex.org/W1603428277","https://openalex.org/W1899927368","https://openalex.org/W1982719471","https://openalex.org/W1996296142","https://openalex.org/W2020438216","https://openalex.org/W2028712328","https://openalex.org/W2048995080","https://openalex.org/W2072005378","https://openalex.org/W2082029512","https://openalex.org/W2097571405","https://openalex.org/W2100588415","https://openalex.org/W2110460556","https://openalex.org/W2113749416","https://openalex.org/W2126432641","https://openalex.org/W2333296258","https://openalex.org/W2345517693","https://openalex.org/W2378259131","https://openalex.org/W2399948660","https://openalex.org/W2432066326","https://openalex.org/W2480013739","https://openalex.org/W2576116471","https://openalex.org/W2588907938","https://openalex.org/W2605207075","https://openalex.org/W2615909376","https://openalex.org/W2900087109","https://openalex.org/W2942432243","https://openalex.org/W2944968364","https://openalex.org/W2946127399","https://openalex.org/W2950837188","https://openalex.org/W2972864379","https://openalex.org/W2980548235","https://openalex.org/W4214749473","https://openalex.org/W4246752648","https://openalex.org/W6636316424","https://openalex.org/W6704484746","https://openalex.org/W6764266315"],"related_works":["https://openalex.org/W2364922518","https://openalex.org/W1995422305","https://openalex.org/W2361860382","https://openalex.org/W2379531326","https://openalex.org/W2604557458","https://openalex.org/W2544485685","https://openalex.org/W2353006359","https://openalex.org/W2504405865","https://openalex.org/W2738065864","https://openalex.org/W2038503502"],"abstract_inverted_index":{"Flow-based":[0],"microfluidic":[1],"biochips":[2,86],"have":[3],"attracted":[4],"much":[5],"attention":[6],"in":[7,138],"the":[8,24,39,79,104,109,123,134,139],"EDA":[9],"community":[10],"due":[11],"to":[12,53],"their":[13],"miniaturized":[14],"size":[15],"and":[16,74,83,154],"execution":[17,94,124],"efficiency.":[18],"Previous":[19],"research,":[20],"however,":[21],"still":[22],"follows":[23],"traditional":[25],"computing":[26],"model":[27],"with":[28,87,97,157],"a":[29,36,48,70,92,116,127],"dedicated":[30,71],"storage":[31,63,72,84],"unit,":[32],"which":[33],"actually":[34],"becomes":[35],"bottleneck":[37],"of":[38,41,81,111,126,136],"performance":[40],"biochips.":[42],"In":[43],"this":[44,88],"article,":[45],"we":[46,101],"propose":[47],"distributed":[49,62],"channel-storage":[50],"architecture":[51,89],"(DCSA)":[52],"cache":[54],"fluid":[55,113],"samples":[56],"inside":[57],"flow":[58,146],"channels":[59,75],"temporarily.":[60],"Since":[61],"can":[64,76,90,129,141,151],"be":[65,130,142,152],"accessed":[66],"more":[67],"efficiently":[68],"than":[69],"unit":[73],"switch":[77],"between":[78],"roles":[80],"transportation":[82,149],"easily,":[85],"achieve":[91],"higher":[93],"efficiency":[95,125],"even":[96],"fewer":[98],"resources.":[99,160],"Furthermore,":[100],"also":[102],"address":[103],"flow-path":[105],"planning":[106],"that":[107,122],"enables":[108],"manipulation":[110],"actual":[112],"transportation/caching":[114],"on":[115],"chip.":[117],"The":[118],"simulation":[119],"results":[120],"confirm":[121],"bioassay":[128],"improved":[131],"significantly,":[132],"while":[133],"number":[135],"valves":[137],"biochip":[140],"reduced":[143],"accordingly.":[144],"Also,":[145],"paths":[147],"for":[148],"tasks":[150],"constructed":[153],"planned":[155],"automatically":[156],"minimum":[158],"extra":[159]},"counts_by_year":[{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":6},{"year":2021,"cited_by_count":9},{"year":2020,"cited_by_count":1}],"updated_date":"2026-06-11T09:08:48.828518","created_date":"2025-10-10T00:00:00"}