{"id":"https://openalex.org/W4414934169","doi":"https://doi.org/10.1109/tbme.2025.3618103","title":"A 3D Numerical Model of Ultrasonic Transthoracic Propagation for Cardiac Focused Ultrasound Therapy","display_name":"A 3D Numerical Model of Ultrasonic Transthoracic Propagation for Cardiac Focused Ultrasound Therapy","publication_year":2025,"publication_date":"2025-10-06","ids":{"openalex":"https://openalex.org/W4414934169","doi":"https://doi.org/10.1109/tbme.2025.3618103","pmid":"https://pubmed.ncbi.nlm.nih.gov/41052173"},"language":"en","primary_location":{"id":"doi:10.1109/tbme.2025.3618103","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tbme.2025.3618103","pdf_url":null,"source":{"id":"https://openalex.org/S5240358","display_name":"IEEE Transactions on Biomedical Engineering","issn_l":"0018-9294","issn":["0018-9294","1558-2531"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Biomedical Engineering","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5055972334","display_name":"Clara Magnier","orcid":null},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4387153500","display_name":"Physique pour la m\u00e9decine Paris","ror":"https://ror.org/03y7m8990","country_code":null,"type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I190752583","https://openalex.org/I2746051580","https://openalex.org/I2746051580","https://openalex.org/I4387153500","https://openalex.org/I98910050"]},{"id":"https://openalex.org/I98910050","display_name":"ESPCI Paris","ror":"https://ror.org/03zx86w41","country_code":"FR","type":"education","lineage":["https://openalex.org/I190752583","https://openalex.org/I2746051580","https://openalex.org/I98910050"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Clara Magnier","raw_affiliation_strings":["Physics for Medicine Paris, Inserm, ESPCI PSL Paris, CNRS, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Physics for Medicine Paris, Inserm, ESPCI PSL Paris, CNRS, Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I98910050","https://openalex.org/I1294671590","https://openalex.org/I4387153500"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063784223","display_name":"Wojciech Kwiecinski","orcid":null},"institutions":[{"id":"https://openalex.org/I4210111582","display_name":"Honeywell (France)","ror":"https://ror.org/01ymvpb42","country_code":"FR","type":"company","lineage":["https://openalex.org/I4210111582","https://openalex.org/I82514191"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Wojciech Kwiecinski","raw_affiliation_strings":["Cardiawave SA, Levallois-Perret, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiawave SA, Levallois-Perret, France","institution_ids":["https://openalex.org/I4210111582"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090439815","display_name":"Daniel Suarez Escudero","orcid":"https://orcid.org/0000-0003-4827-6359"},"institutions":[{"id":"https://openalex.org/I4210111582","display_name":"Honeywell (France)","ror":"https://ror.org/01ymvpb42","country_code":"FR","type":"company","lineage":["https://openalex.org/I4210111582","https://openalex.org/I82514191"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Daniel Suarez Escudero","raw_affiliation_strings":["Cardiawave SA, Levallois-Perret, France"],"raw_orcid":"https://orcid.org/0000-0003-4827-6359","affiliations":[{"raw_affiliation_string":"Cardiawave SA, Levallois-Perret, France","institution_ids":["https://openalex.org/I4210111582"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5119893173","display_name":"Gauthier Amis","orcid":null},"institutions":[{"id":"https://openalex.org/I4210111582","display_name":"Honeywell (France)","ror":"https://ror.org/01ymvpb42","country_code":"FR","type":"company","lineage":["https://openalex.org/I4210111582","https://openalex.org/I82514191"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Gauthier Amis","raw_affiliation_strings":["Cardiawave SA, Levallois-Perret, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiawave SA, Levallois-Perret, France","institution_ids":["https://openalex.org/I4210111582"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084679716","display_name":"Guillaume Goudot","orcid":"https://orcid.org/0000-0003-4327-5568"},"institutions":[{"id":"https://openalex.org/I4210097159","display_name":"Assistance Publique \u2013 H\u00f4pitaux de Paris","ror":"https://ror.org/00pg5jh14","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159"]},{"id":"https://openalex.org/I4210102325","display_name":"H\u00f4pital Europ\u00e9en Georges-Pompidou","ror":"https://ror.org/016vx5156","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210102325","https://openalex.org/I4210120235"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Guillaume Goudot","raw_affiliation_strings":["Hôpital Européen Georges Pompidou, APHP, Paris, France"],"raw_orcid":"https://orcid.org/0000-0003-4327-5568","affiliations":[{"raw_affiliation_string":"Hôpital Européen Georges Pompidou, APHP, Paris, France","institution_ids":["https://openalex.org/I4210102325","https://openalex.org/I4210097159"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058102414","display_name":"\u00c9lie Mousseaux","orcid":"https://orcid.org/0000-0002-8076-1445"},"institutions":[{"id":"https://openalex.org/I4210097159","display_name":"Assistance Publique \u2013 H\u00f4pitaux de Paris","ror":"https://ror.org/00pg5jh14","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159"]},{"id":"https://openalex.org/I4210102325","display_name":"H\u00f4pital Europ\u00e9en Georges-Pompidou","ror":"https://ror.org/016vx5156","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210102325","https://openalex.org/I4210120235"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Elie Mousseaux","raw_affiliation_strings":["Hôpital Européen Georges Pompidou, APHP, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hôpital Européen Georges Pompidou, APHP, Paris, France","institution_ids":["https://openalex.org/I4210102325","https://openalex.org/I4210097159"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089215000","display_name":"Emmanuel Messas","orcid":"https://orcid.org/0000-0003-3214-7501"},"institutions":[{"id":"https://openalex.org/I4210097159","display_name":"Assistance Publique \u2013 H\u00f4pitaux de Paris","ror":"https://ror.org/00pg5jh14","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159"]},{"id":"https://openalex.org/I4210102325","display_name":"H\u00f4pital Europ\u00e9en Georges-Pompidou","ror":"https://ror.org/016vx5156","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210102325","https://openalex.org/I4210120235"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Emmanuel Messas","raw_affiliation_strings":["Hôpital Européen Georges Pompidou, APHP, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hôpital Européen Georges Pompidou, APHP, Paris, France","institution_ids":["https://openalex.org/I4210102325","https://openalex.org/I4210097159"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5006303586","display_name":"Mathieu Pernot","orcid":"https://orcid.org/0000-0001-6713-4642"},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4387153500","display_name":"Physique pour la m\u00e9decine Paris","ror":"https://ror.org/03y7m8990","country_code":null,"type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I190752583","https://openalex.org/I2746051580","https://openalex.org/I2746051580","https://openalex.org/I4387153500","https://openalex.org/I98910050"]},{"id":"https://openalex.org/I98910050","display_name":"ESPCI Paris","ror":"https://ror.org/03zx86w41","country_code":"FR","type":"education","lineage":["https://openalex.org/I190752583","https://openalex.org/I2746051580","https://openalex.org/I98910050"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Mathieu Pernot","raw_affiliation_strings":["Physics for Medicine Paris, Inserm, ESPCI PSL Paris, CNRS, Paris, France"],"raw_orcid":"https://orcid.org/0000-0001-6713-4642","affiliations":[{"raw_affiliation_string":"Physics for Medicine Paris, Inserm, ESPCI PSL Paris, CNRS, Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I98910050","https://openalex.org/I1294671590","https://openalex.org/I4387153500"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":8,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.4905,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.67292948,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":95},"biblio":{"volume":"73","issue":"5","first_page":"1933","last_page":"1942"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10958","display_name":"Ultrasound and Hyperthermia Applications","score":0.8754000067710876,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10958","display_name":"Ultrasound and Hyperthermia Applications","score":0.8754000067710876,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10727","display_name":"Ultrasound Imaging and Elastography","score":0.10890000313520432,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11738","display_name":"Ultrasound in Clinical Applications","score":0.00139999995008111,"subfield":{"id":"https://openalex.org/subfields/2706","display_name":"Critical Care and Intensive Care Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ultrasonic-sensor","display_name":"Ultrasonic sensor","score":0.7095000147819519},{"id":"https://openalex.org/keywords/ultrasonic-imaging","display_name":"Ultrasonic imaging","score":0.5652999877929688},{"id":"https://openalex.org/keywords/focused-ultrasound","display_name":"Focused ultrasound","score":0.5511999726295471},{"id":"https://openalex.org/keywords/ultrasound","display_name":"Ultrasound","score":0.4779999852180481},{"id":"https://openalex.org/keywords/cardiac-ultrasound","display_name":"Cardiac Ultrasound","score":0.4611999988555908},{"id":"https://openalex.org/keywords/numerical-models","display_name":"Numerical models","score":0.35269999504089355}],"concepts":[{"id":"https://openalex.org/C81288441","wikidata":"https://www.wikidata.org/wiki/Q20736125","display_name":"Ultrasonic sensor","level":2,"score":0.7095000147819519},{"id":"https://openalex.org/C2989478337","wikidata":"https://www.wikidata.org/wiki/Q234904","display_name":"Ultrasonic imaging","level":3,"score":0.5652999877929688},{"id":"https://openalex.org/C2985948822","wikidata":"https://www.wikidata.org/wiki/Q564897","display_name":"Focused ultrasound","level":3,"score":0.5511999726295471},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.542900025844574},{"id":"https://openalex.org/C143753070","wikidata":"https://www.wikidata.org/wiki/Q162564","display_name":"Ultrasound","level":2,"score":0.4779999852180481},{"id":"https://openalex.org/C2910830941","wikidata":"https://www.wikidata.org/wiki/Q216933","display_name":"Cardiac Ultrasound","level":3,"score":0.4611999988555908},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.41909998655319214},{"id":"https://openalex.org/C24890656","wikidata":"https://www.wikidata.org/wiki/Q82811","display_name":"Acoustics","level":1,"score":0.362199991941452},{"id":"https://openalex.org/C2986605239","wikidata":"https://www.wikidata.org/wiki/Q925667","display_name":"Numerical models","level":3,"score":0.35269999504089355},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3199000060558319},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.30970001220703125},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.3089999854564667},{"id":"https://openalex.org/C529618451","wikidata":"https://www.wikidata.org/wiki/Q234904","display_name":"Ultrasonography","level":2,"score":0.27959999442100525},{"id":"https://openalex.org/C19527891","wikidata":"https://www.wikidata.org/wiki/Q1120908","display_name":"Medical physics","level":1,"score":0.2770000100135803},{"id":"https://openalex.org/C108882727","wikidata":"https://www.wikidata.org/wiki/Q2991685","display_name":"Solid modeling","level":2,"score":0.267300009727478},{"id":"https://openalex.org/C2777365067","wikidata":"https://www.wikidata.org/wiki/Q564897","display_name":"High-intensity focused ultrasound","level":3,"score":0.25859999656677246},{"id":"https://openalex.org/C2989031253","wikidata":"https://www.wikidata.org/wiki/Q925667","display_name":"Numerical modeling","level":2,"score":0.2581000030040741},{"id":"https://openalex.org/C135628077","wikidata":"https://www.wikidata.org/wiki/Q220184","display_name":"Finite element method","level":2,"score":0.25189998745918274}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006321","descriptor_name":"Heart","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D006321","descriptor_name":"Heart","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008955","descriptor_name":"Models, Cardiovascular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012272","descriptor_name":"Ribs","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D013552","descriptor_name":"Swine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014464","descriptor_name":"Ultrasonic Therapy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D021621","descriptor_name":"Imaging, Three-Dimensional","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1109/tbme.2025.3618103","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tbme.2025.3618103","pdf_url":null,"source":{"id":"https://openalex.org/S5240358","display_name":"IEEE Transactions on Biomedical Engineering","issn_l":"0018-9294","issn":["0018-9294","1558-2531"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Biomedical Engineering","raw_type":"journal-article"},{"id":"pmid:41052173","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41052173","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE transactions on bio-medical engineering","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":38,"referenced_works":["https://openalex.org/W1979872711","https://openalex.org/W1980154864","https://openalex.org/W1996996820","https://openalex.org/W1998953558","https://openalex.org/W1999318406","https://openalex.org/W2006834824","https://openalex.org/W2011863710","https://openalex.org/W2021561714","https://openalex.org/W2022074509","https://openalex.org/W2025191689","https://openalex.org/W2025766117","https://openalex.org/W2029011692","https://openalex.org/W2036413170","https://openalex.org/W2036848332","https://openalex.org/W2044618661","https://openalex.org/W2051273237","https://openalex.org/W2052946230","https://openalex.org/W2063812299","https://openalex.org/W2065753258","https://openalex.org/W2075234067","https://openalex.org/W2075429966","https://openalex.org/W2077334475","https://openalex.org/W2111589632","https://openalex.org/W2171748944","https://openalex.org/W2531265884","https://openalex.org/W2587443020","https://openalex.org/W2741478648","https://openalex.org/W2886611927","https://openalex.org/W2899897962","https://openalex.org/W2961801754","https://openalex.org/W3042887616","https://openalex.org/W3157891137","https://openalex.org/W4283749262","https://openalex.org/W4293008336","https://openalex.org/W4308366336","https://openalex.org/W4309087689","https://openalex.org/W4383218413","https://openalex.org/W4388656965"],"related_works":[],"abstract_inverted_index":{"Objective:":[0],"Non-invasive":[1],"focused":[2],"ultrasound":[3,23,222],"therapies":[4],"of":[5,22,34,64,112,130,159,177,193,220],"abdominal":[6],"organs,":[7],"including":[8],"the":[9,12,17,42,83,134,143,153,164,167,178,181,194,207],"heart":[10],"and":[11,30,60,75,120,136,155,226],"liver,":[13],"have":[14,37],"emerged":[15],"in":[16,44,116,121],"last":[18],"decades.":[19],"Transthoracic":[20],"focusing":[21],"poses":[24],"challenges":[25],"such":[26],"as":[27,242],"pressure":[28,113,131,138,157],"loss":[29],"aberrations.":[31],"Numerical":[32],"models":[33,53,66],"ultrasonic":[35,84,249],"propagation":[36,85,145,223],"been":[38,68],"developed":[39],"to":[40,81,91,210],"study":[41],"focalization":[43],"heterogeneous":[45],"tissues,":[46],"particularly":[47],"for":[48,142,247],"transcranial":[49],"applications.":[50],"However,":[51],"ribcage":[52,65],"were":[54,79,98],"less":[55],"studied":[56],"than":[57],"skull":[58],"models,":[59],"no":[61],"experimental":[62],"validation":[63,106],"has":[67],"performed":[69,108],"so":[70],"far.":[71],"Methods:":[72],"Both":[73],"linear":[74,144],"nonlinear":[76,165],"k-space":[77],"simulations":[78,179],"used":[80,227,241],"model":[82,105,146,219,238],"from":[86,100],"a":[87,148,229,243],"clinical":[88],"system":[89],"dedicated":[90],"transthoracic":[92,221],"cardiac":[93,250],"therapy.":[94,251],"Tissue":[95],"acoustic":[96],"properties":[97],"determined":[99],"computed":[101],"tomography":[102],"scans.":[103],"Experimental":[104],"was":[107,140,171,184,202,224],"with":[109,147],"hydrophone":[110],"measurements":[111],"fields":[114,139,158],"through":[115,180],"vitro":[117,122],"human":[118,182,230],"ribs":[119],"porcine":[123],"flail":[124],"chest.":[125],"Results:":[126],"An":[127],"excellent":[128],"agreement":[129],"distribution":[132],"between":[133,152],"acquired":[135],"simulated":[137,156],"found":[141],"mean":[149,168],"correlation":[150,169],"coefficient":[151,170],"measured":[154],"R2":[160,172],"=":[161,173,214],"0.89\u00b10.07.":[162],"For":[163],"propagation,":[166],"0.91\u00b10.06.":[174],"The":[175,197,217],"feasibility":[176],"thorax":[183],"demonstrated":[185],"on":[186,228],"9":[187],"patients":[188],"who":[189],"underwent":[190],"non-invasive":[191,248],"therapy":[192],"aortic":[195],"valve.":[196],"global":[198],"attenuation":[199],"estimated":[200],"numerically":[201],"correlated":[203],"withthe":[204],"amplitude":[205],"at":[206],"focus":[208],"necessary":[209],"nucleate":[211],"cavitation":[212],"(R2":[213],"0.64).":[215],"Conclusion:":[216],"numerical":[218],"validated":[225],"patient's":[231],"thorax.":[232],"Significance:":[233],"With":[234],"further":[235],"development,":[236],"this":[237],"could":[239],"be":[240],"treatment":[244],"planning":[245],"tool":[246]},"counts_by_year":[{"year":2025,"cited_by_count":1}],"updated_date":"2026-06-11T09:08:48.828518","created_date":"2025-10-10T00:00:00"}