{"id":"https://openalex.org/W4406458668","doi":"https://doi.org/10.1109/tbme.2025.3530711","title":"Personalized Model Identification for Glucose Dynamics From Clinical Data With Incomplete Inputs","display_name":"Personalized Model Identification for Glucose Dynamics From Clinical Data With Incomplete Inputs","publication_year":2025,"publication_date":"2025-01-16","ids":{"openalex":"https://openalex.org/W4406458668","doi":"https://doi.org/10.1109/tbme.2025.3530711","pmid":"https://pubmed.ncbi.nlm.nih.gov/40030928"},"language":"en","primary_location":{"id":"doi:10.1109/tbme.2025.3530711","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tbme.2025.3530711","pdf_url":null,"source":{"id":"https://openalex.org/S5240358","display_name":"IEEE Transactions on Biomedical Engineering","issn_l":"0018-9294","issn":["0018-9294","1558-2531"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Biomedical Engineering","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5051053161","display_name":"Ba\u015fak \u00d6zaslan","orcid":"https://orcid.org/0000-0002-8537-1892"},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I2801851002","display_name":"Harvard University Press","ror":"https://ror.org/006v7bf86","country_code":"US","type":"other","lineage":["https://openalex.org/I136199984","https://openalex.org/I2801851002"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Basak Ozaslan","raw_affiliation_strings":["Harvard John A. Paulson School of Engineering and Applied Sciences, Harvard University, USA","Harvard John A. Paulson School Of Engineering And Applied Sciences, Harvard University, Cambridge, MA, U.K"],"raw_orcid":"https://orcid.org/0000-0002-8537-1892","affiliations":[{"raw_affiliation_string":"Harvard John A. Paulson School of Engineering and Applied Sciences, Harvard University, USA","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Harvard John A. Paulson School Of Engineering And Applied Sciences, Harvard University, Cambridge, MA, U.K","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I2801851002"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065275114","display_name":"Eleonora M. Aiello","orcid":"https://orcid.org/0000-0001-5129-8829"},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I2801851002","display_name":"Harvard University Press","ror":"https://ror.org/006v7bf86","country_code":"US","type":"other","lineage":["https://openalex.org/I136199984","https://openalex.org/I2801851002"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eleonora M. Aiello","raw_affiliation_strings":["Harvard John A. Paulson School of Engineering and Applied Sciences, Harvard University, USA","Harvard John A. Paulson School Of Engineering And Applied Sciences, Harvard University, Cambridge, MA, U.K"],"raw_orcid":"https://orcid.org/0000-0001-5129-8829","affiliations":[{"raw_affiliation_string":"Harvard John A. Paulson School of Engineering and Applied Sciences, Harvard University, USA","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Harvard John A. Paulson School Of Engineering And Applied Sciences, Harvard University, Cambridge, MA, U.K","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I2801851002"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081355923","display_name":"Emilia Fushimi","orcid":"https://orcid.org/0000-0001-5820-3108"},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I2801851002","display_name":"Harvard University Press","ror":"https://ror.org/006v7bf86","country_code":"US","type":"other","lineage":["https://openalex.org/I136199984","https://openalex.org/I2801851002"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Emilia Fushimi","raw_affiliation_strings":["Harvard John A. Paulson School of Engineering and Applied Sciences, Harvard University, USA","Harvard John A. Paulson School Of Engineering And Applied Sciences, Harvard University, Cambridge, MA, U.K"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Harvard John A. Paulson School of Engineering and Applied Sciences, Harvard University, USA","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Harvard John A. Paulson School Of Engineering And Applied Sciences, Harvard University, Cambridge, MA, U.K","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I2801851002"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081288689","display_name":"Francis J. Doyle","orcid":"https://orcid.org/0000-0002-3293-9114"},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I2801851002","display_name":"Harvard University Press","ror":"https://ror.org/006v7bf86","country_code":"US","type":"other","lineage":["https://openalex.org/I136199984","https://openalex.org/I2801851002"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Francis J. Doyle","raw_affiliation_strings":["Harvard John A. Paulson School of Engineering and Applied Sciences, Harvard University, USA","Harvard John A. Paulson School Of Engineering And Applied Sciences, Harvard University, Cambridge, MA, U.K"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Harvard John A. Paulson School of Engineering and Applied Sciences, Harvard University, USA","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Harvard John A. Paulson School Of Engineering And Applied Sciences, Harvard University, Cambridge, MA, U.K","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I2801851002"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5007855159","display_name":"Eyal Dassau","orcid":"https://orcid.org/0000-0001-5333-6892"},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I2801851002","display_name":"Harvard University Press","ror":"https://ror.org/006v7bf86","country_code":"US","type":"other","lineage":["https://openalex.org/I136199984","https://openalex.org/I2801851002"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eyal Dassau","raw_affiliation_strings":["Harvard John A. Paulson School of Engineering and Applied Sciences, Harvard University, Boston, USA","Harvard John A. Paulson School Of Engineering And Applied Sciences, Harvard University, Cambridge, MA, U.K"],"raw_orcid":"https://orcid.org/0000-0001-5333-6892","affiliations":[{"raw_affiliation_string":"Harvard John A. Paulson School of Engineering and Applied Sciences, Harvard University, Boston, USA","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Harvard John A. Paulson School Of Engineering And Applied Sciences, Harvard University, Cambridge, MA, U.K","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I2801851002"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5051053161"],"corresponding_institution_ids":["https://openalex.org/I136199984","https://openalex.org/I2801851002"],"apc_list":null,"apc_paid":null,"fwci":3.0992,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.90652105,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":91,"max":99},"biblio":{"volume":"72","issue":"6","first_page":"2001","last_page":"2012"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10560","display_name":"Diabetes Management and Research","score":0.9397000074386597,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10560","display_name":"Diabetes Management and Research","score":0.9397000074386597,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11623","display_name":"Hyperglycemia and glycemic control in critically ill and hospitalized patients","score":0.006200000178068876,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10839","display_name":"Pancreatic function and diabetes","score":0.004900000058114529,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/identification","display_name":"Identification (biology)","score":0.6516707539558411},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6029849648475647},{"id":"https://openalex.org/keywords/data-modeling","display_name":"Data modeling","score":0.5230917930603027},{"id":"https://openalex.org/keywords/dynamics","display_name":"Dynamics (music)","score":0.4334741234779358},{"id":"https://openalex.org/keywords/system-identification","display_name":"System identification","score":0.43085652589797974},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.3456227481365204},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.09947794675827026},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.09401926398277283}],"concepts":[{"id":"https://openalex.org/C116834253","wikidata":"https://www.wikidata.org/wiki/Q2039217","display_name":"Identification (biology)","level":2,"score":0.6516707539558411},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6029849648475647},{"id":"https://openalex.org/C67186912","wikidata":"https://www.wikidata.org/wiki/Q367664","display_name":"Data modeling","level":2,"score":0.5230917930603027},{"id":"https://openalex.org/C145912823","wikidata":"https://www.wikidata.org/wiki/Q113558","display_name":"Dynamics (music)","level":2,"score":0.4334741234779358},{"id":"https://openalex.org/C119247159","wikidata":"https://www.wikidata.org/wiki/Q1366192","display_name":"System identification","level":3,"score":0.43085652589797974},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.3456227481365204},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.09947794675827026},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.09401926398277283},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.0},{"id":"https://openalex.org/C24890656","wikidata":"https://www.wikidata.org/wiki/Q82811","display_name":"Acoustics","level":1,"score":0.0},{"id":"https://openalex.org/C77088390","wikidata":"https://www.wikidata.org/wiki/Q8513","display_name":"Database","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001786","descriptor_name":"Blood Glucose","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D001786","descriptor_name":"Blood Glucose","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D001786","descriptor_name":"Blood Glucose","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D001786","descriptor_name":"Blood Glucose","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D001786","descriptor_name":"Blood Glucose","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D001786","descriptor_name":"Blood Glucose","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D001786","descriptor_name":"Blood Glucose","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D001786","descriptor_name":"Blood Glucose","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D001786","descriptor_name":"Blood Glucose","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D001786","descriptor_name":"Blood Glucose","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D003922","descriptor_name":"Diabetes Mellitus, Type 1","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D003922","descriptor_name":"Diabetes Mellitus, Type 1","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D003922","descriptor_name":"Diabetes Mellitus, Type 1","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D003922","descriptor_name":"Diabetes Mellitus, Type 1","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D003922","descriptor_name":"Diabetes Mellitus, Type 1","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D003922","descriptor_name":"Diabetes Mellitus, Type 1","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D003922","descriptor_name":"Diabetes Mellitus, Type 1","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D003922","descriptor_name":"Diabetes Mellitus, Type 1","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D003922","descriptor_name":"Diabetes Mellitus, Type 1","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D003922","descriptor_name":"Diabetes Mellitus, Type 1","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007328","descriptor_name":"Insulin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007328","descriptor_name":"Insulin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007328","descriptor_name":"Insulin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007328","descriptor_name":"Insulin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007328","descriptor_name":"Insulin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016018","descriptor_name":"Least-Squares Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016018","descriptor_name":"Least-Squares Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016018","descriptor_name":"Least-Squares Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016018","descriptor_name":"Least-Squares Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016018","descriptor_name":"Least-Squares Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057285","descriptor_name":"Precision Medicine","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D057285","descriptor_name":"Precision Medicine","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D057285","descriptor_name":"Precision Medicine","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D057285","descriptor_name":"Precision Medicine","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D057285","descriptor_name":"Precision Medicine","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1109/tbme.2025.3530711","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tbme.2025.3530711","pdf_url":null,"source":{"id":"https://openalex.org/S5240358","display_name":"IEEE Transactions on Biomedical Engineering","issn_l":"0018-9294","issn":["0018-9294","1558-2531"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Biomedical Engineering","raw_type":"journal-article"},{"id":"pmid:40030928","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40030928","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE transactions on bio-medical engineering","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/2","score":0.44999998807907104,"display_name":"Zero hunger"}],"awards":[{"id":"https://openalex.org/G5937596477","display_name":null,"funder_award_id":"G-2204-05196","funder_id":"https://openalex.org/F4320309446","funder_display_name":"Leona M. and Harry B. Helmsley Charitable Trust"},{"id":"https://openalex.org/G7005728810","display_name":null,"funder_award_id":"R01DK120358","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G7385589889","display_name":null,"funder_award_id":"AP-2020-014","funder_id":"https://openalex.org/F4320316051","funder_display_name":"Dexcom"}],"funders":[{"id":"https://openalex.org/F4320309446","display_name":"Leona M. and Harry B. Helmsley Charitable Trust","ror":"https://ror.org/011x6n313"},{"id":"https://openalex.org/F4320316051","display_name":"Dexcom","ror":"https://ror.org/03ra42c27"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":32,"referenced_works":["https://openalex.org/W1973553754","https://openalex.org/W1977918122","https://openalex.org/W2016786688","https://openalex.org/W2024487933","https://openalex.org/W2044877664","https://openalex.org/W2061310674","https://openalex.org/W2125199656","https://openalex.org/W2152099601","https://openalex.org/W2157856672","https://openalex.org/W2337250735","https://openalex.org/W2464472116","https://openalex.org/W2523526638","https://openalex.org/W2765581794","https://openalex.org/W2767819117","https://openalex.org/W2783941344","https://openalex.org/W2788900605","https://openalex.org/W2790915589","https://openalex.org/W2886519109","https://openalex.org/W2973017644","https://openalex.org/W2978488577","https://openalex.org/W3013045429","https://openalex.org/W3067193962","https://openalex.org/W3103205051","https://openalex.org/W3106920072","https://openalex.org/W3173676681","https://openalex.org/W3182564703","https://openalex.org/W3204080639","https://openalex.org/W4214738836","https://openalex.org/W4241368925","https://openalex.org/W4376868020","https://openalex.org/W4388917899","https://openalex.org/W4390462129"],"related_works":["https://openalex.org/W2898732673","https://openalex.org/W2410053581","https://openalex.org/W2383658677","https://openalex.org/W3123203398","https://openalex.org/W1972473893","https://openalex.org/W2466435674","https://openalex.org/W2765200542","https://openalex.org/W1636325709","https://openalex.org/W2382161936","https://openalex.org/W176335707"],"abstract_inverted_index":{"OBJECTIVE:":[0],"A":[1],"common":[2],"challenge":[3],"in":[4,29,72,167,179,192,207,216,236],"model":[5,42,70,145,153,170,181,208],"identification":[6,209],"with":[7,47,74,142,155,169,187,213,222,238],"clinical":[8,31,137,211],"data":[9,28,111,138,174,186,212],"is":[10,56,92,120,134,147,205],"incomplete":[11],"and":[12,64,99,229],"sometimes":[13],"imprecise":[14],"information.":[15],"In":[16,81],"this":[17],"work,":[18],"we":[19,125],"provide":[20],"a":[21,30,40,110,127],"method":[22,55,133,204],"to":[23,68,77,83,94,122,149,163,176,231],"reconstruct":[24],"the":[25,36,78,89,103,115,118,150,180,217],"corrupted":[26],"input":[27,79],"dataset":[32],"and,":[33],"jointly":[34],"identify":[35],"person-specific":[37],"parameters":[38,71,171],"of":[39,87,106,117,152],"metabolic":[41],"describing":[43],"meal-insulin-glucose-dynamics":[44],"for":[45,194,210],"people":[46,141,237],"type":[48],"1":[49],"diabetes":[50],"(T1D).":[51],"METHOD:":[52],"The":[53,132,202],"proposed":[54,203],"an":[57,177,188],"algorithm":[58],"that":[59],"iterates":[60],"between":[61],"nonlinear":[62],"least-squares":[63],"mixed-integer":[65],"quadratic":[66],"programming":[67],"optimize":[69],"conjunction":[73,168],"sparse":[75],"corrections":[76,166],"data.":[80],"order":[82],"handle":[84],"long":[85],"stretches":[86],"data,":[88],"optimization":[90],"problem":[91],"designed":[93],"be":[95],"i)":[96],"computationally":[97],"tractable,":[98],"ii)":[100],"robust":[101],"against":[102],"potential":[104],"presence":[105],"significant":[107],"inaccuracies":[108,119,215],"corrupting":[109],"portion.":[112],"Moreover,":[113],"since":[114],"pattern":[116],"specific":[121],"each":[123],"person,":[124],"propose":[126],"personalized":[128],"hyperparameter":[129],"tuning":[130],"approach.":[131],"applied":[135],"on":[136,172,184],"from":[139],"13":[140],"T1D.":[143,239],"Identified":[144],"performance":[146,151],"compared":[148],"identified":[154],"standard":[156],"least":[157],"squares":[158],"(LS)":[159],"method.":[160],"RESULTS:":[161],"Compared":[162],"LS,":[164],"identifying":[165],"training":[173],"lead":[175,230],"improvement":[178,191],"prediction":[182,196],"capabilities":[183],"unseen":[185],"average":[189],"2.2%":[190],"MARD":[193],"two-hour":[195],"horizon":[197],"(p-value":[198],"=":[199],"0.0006).":[200],"CONCLUSIONS:":[201],"effective":[206],"unknown":[214],"inputs.":[218],"SIGNIFICANCE:":[219],"Personalized":[220],"models":[221],"high":[223],"accuracy":[224],"can":[225],"inform":[226],"treatment":[227],"decisions":[228],"better":[232],"glucose":[233],"control":[234],"outcomes":[235]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":1}],"updated_date":"2026-04-29T09:16:38.111599","created_date":"2025-10-10T00:00:00"}