{"id":"https://openalex.org/W4386902930","doi":"https://doi.org/10.1109/tbme.2023.3317400","title":"High-Energy Pacing in the Jejunum Elicits Pulsatile Segmental Contractions","display_name":"High-Energy Pacing in the Jejunum Elicits Pulsatile Segmental Contractions","publication_year":2023,"publication_date":"2023-09-20","ids":{"openalex":"https://openalex.org/W4386902930","doi":"https://doi.org/10.1109/tbme.2023.3317400","pmid":"https://pubmed.ncbi.nlm.nih.gov/37729575"},"language":"en","primary_location":{"id":"doi:10.1109/tbme.2023.3317400","is_oa":true,"landing_page_url":"https://doi.org/10.1109/tbme.2023.3317400","pdf_url":"https://ieeexplore.ieee.org/ielx7/10/4359967/10256040.pdf","source":{"id":"https://openalex.org/S5240358","display_name":"IEEE Transactions on Biomedical Engineering","issn_l":"0018-9294","issn":["0018-9294","1558-2531"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Biomedical Engineering","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://ieeexplore.ieee.org/ielx7/10/4359967/10256040.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5048530964","display_name":"Nipuni D. Nagahawatte","orcid":"https://orcid.org/0000-0002-1409-447X"},"institutions":[{"id":"https://openalex.org/I154130895","display_name":"University of Auckland","ror":"https://ror.org/03b94tp07","country_code":"NZ","type":"education","lineage":["https://openalex.org/I154130895"]}],"countries":["NZ"],"is_corresponding":false,"raw_author_name":"Nipuni D. Nagahawatte","raw_affiliation_strings":["Auckland Bioengineering Institute, University of Auckland, New Zealand","Auckland Bioengineering Institute, University of Auckland, Auckland, New Zealand"],"raw_orcid":"https://orcid.org/0000-0002-1409-447X","affiliations":[{"raw_affiliation_string":"Auckland Bioengineering Institute, University of Auckland, New Zealand","institution_ids":["https://openalex.org/I154130895"]},{"raw_affiliation_string":"Auckland Bioengineering Institute, University of Auckland, Auckland, New Zealand","institution_ids":["https://openalex.org/I154130895"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073924257","display_name":"Recep Avci","orcid":"https://orcid.org/0000-0003-2652-2192"},"institutions":[{"id":"https://openalex.org/I154130895","display_name":"University of Auckland","ror":"https://ror.org/03b94tp07","country_code":"NZ","type":"education","lineage":["https://openalex.org/I154130895"]}],"countries":["NZ"],"is_corresponding":false,"raw_author_name":"Recep Avci","raw_affiliation_strings":["Auckland Bioengineering Institute, University of Auckland, New Zealand","Auckland Bioengineering Institute, University of Auckland, Auckland, New Zealand"],"raw_orcid":"https://orcid.org/0000-0003-2652-2192","affiliations":[{"raw_affiliation_string":"Auckland Bioengineering Institute, University of Auckland, New Zealand","institution_ids":["https://openalex.org/I154130895"]},{"raw_affiliation_string":"Auckland Bioengineering Institute, University of Auckland, Auckland, New Zealand","institution_ids":["https://openalex.org/I154130895"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010008127","display_name":"Timothy R. Angeli","orcid":"https://orcid.org/0000-0003-1610-3787"},"institutions":[{"id":"https://openalex.org/I154130895","display_name":"University of Auckland","ror":"https://ror.org/03b94tp07","country_code":"NZ","type":"education","lineage":["https://openalex.org/I154130895"]}],"countries":["NZ"],"is_corresponding":false,"raw_author_name":"Timothy R. Angeli-Gordon","raw_affiliation_strings":["Auckland Bioengineering Institute, University of Auckland, New Zealand","Auckland Bioengineering Institute, University of Auckland, Auckland, New Zealand","Department of Surgery, University of Auckland, Auckland, New Zealand"],"raw_orcid":"https://orcid.org/0000-0003-1610-3787","affiliations":[{"raw_affiliation_string":"Auckland Bioengineering Institute, University of Auckland, New Zealand","institution_ids":["https://openalex.org/I154130895"]},{"raw_affiliation_string":"Auckland Bioengineering Institute, University of Auckland, Auckland, New Zealand","institution_ids":["https://openalex.org/I154130895"]},{"raw_affiliation_string":"Department of Surgery, University of Auckland, Auckland, New Zealand","institution_ids":["https://openalex.org/I154130895"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039076247","display_name":"Niranchan Paskaranandavadivel","orcid":"https://orcid.org/0000-0001-7377-8524"},"institutions":[{"id":"https://openalex.org/I154130895","display_name":"University of Auckland","ror":"https://ror.org/03b94tp07","country_code":"NZ","type":"education","lineage":["https://openalex.org/I154130895"]}],"countries":["NZ"],"is_corresponding":false,"raw_author_name":"Niranchan Paskaranandavadivel","raw_affiliation_strings":["Auckland Bioengineering Institute, University of Auckland, New Zealand","Auckland Bioengineering Institute, University of Auckland, Auckland, New Zealand"],"raw_orcid":"https://orcid.org/0000-0001-7377-8524","affiliations":[{"raw_affiliation_string":"Auckland Bioengineering Institute, University of Auckland, New Zealand","institution_ids":["https://openalex.org/I154130895"]},{"raw_affiliation_string":"Auckland Bioengineering Institute, University of Auckland, Auckland, New Zealand","institution_ids":["https://openalex.org/I154130895"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5036297582","display_name":"Leo K. Cheng","orcid":"https://orcid.org/0000-0003-2426-8987"},"institutions":[{"id":"https://openalex.org/I154130895","display_name":"University of Auckland","ror":"https://ror.org/03b94tp07","country_code":"NZ","type":"education","lineage":["https://openalex.org/I154130895"]},{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]},{"id":"https://openalex.org/I4210159946","display_name":"Riddet Institute","ror":"https://ror.org/053336823","country_code":"NZ","type":"facility","lineage":["https://openalex.org/I1320288732","https://openalex.org/I154130895","https://openalex.org/I41125697","https://openalex.org/I4210159946","https://openalex.org/I4405260297","https://openalex.org/I4405260297","https://openalex.org/I51158804","https://openalex.org/I80281795"]}],"countries":["NZ","US"],"is_corresponding":false,"raw_author_name":"Leo K. Cheng","raw_affiliation_strings":["Auckland Bioengineering Institute, University of Auckland, Auckland, New Zealand","Department of Surgery, Vanderbilt University, Nashville, Tennessee, USA","Riddet Institute Centre of Research Excellence, Palmerston North, New Zealand"],"raw_orcid":"https://orcid.org/0000-0003-2426-8987","affiliations":[{"raw_affiliation_string":"Auckland Bioengineering Institute, University of Auckland, Auckland, New Zealand","institution_ids":["https://openalex.org/I154130895"]},{"raw_affiliation_string":"Department of Surgery, Vanderbilt University, Nashville, Tennessee, USA","institution_ids":["https://openalex.org/I200719446"]},{"raw_affiliation_string":"Riddet Institute Centre of Research Excellence, Palmerston North, New Zealand","institution_ids":["https://openalex.org/I4210159946"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.5571,"has_fulltext":true,"cited_by_count":2,"citation_normalized_percentile":{"value":0.68903245,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":95},"biblio":{"volume":"71","issue":"3","first_page":"750","last_page":"757"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12089","display_name":"Intestinal and Peritoneal Adhesions","score":0.44290000200271606,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12089","display_name":"Intestinal and Peritoneal Adhesions","score":0.44290000200271606,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10365","display_name":"Gastrointestinal motility and disorders","score":0.2888000011444092,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12020","display_name":"Enhanced Recovery After Surgery","score":0.147599995136261,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pulsatile-flow","display_name":"Pulsatile flow","score":0.8326150178909302},{"id":"https://openalex.org/keywords/jejunum","display_name":"Jejunum","score":0.6381028890609741},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.461515873670578},{"id":"https://openalex.org/keywords/biomedical-engineering","display_name":"Biomedical engineering","score":0.413211464881897},{"id":"https://openalex.org/keywords/cardiology","display_name":"Cardiology","score":0.4043083190917969},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.36764824390411377},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.3623306453227997}],"concepts":[{"id":"https://openalex.org/C79191276","wikidata":"https://www.wikidata.org/wiki/Q7259620","display_name":"Pulsatile flow","level":2,"score":0.8326150178909302},{"id":"https://openalex.org/C2776366702","wikidata":"https://www.wikidata.org/wiki/Q185765","display_name":"Jejunum","level":2,"score":0.6381028890609741},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.461515873670578},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.413211464881897},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.4043083190917969},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.36764824390411377},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3623306453227997}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004558","descriptor_name":"Electric Stimulation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D004558","descriptor_name":"Electric Stimulation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D004558","descriptor_name":"Electric Stimulation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D004558","descriptor_name":"Electric Stimulation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D005769","descriptor_name":"Gastrointestinal Motility","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D005769","descriptor_name":"Gastrointestinal Motility","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D005769","descriptor_name":"Gastrointestinal Motility","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D005769","descriptor_name":"Gastrointestinal Motility","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D007421","descriptor_name":"Intestine, Small","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007421","descriptor_name":"Intestine, Small","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007421","descriptor_name":"Intestine, Small","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007421","descriptor_name":"Intestine, Small","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007583","descriptor_name":"Jejunum","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D007583","descriptor_name":"Jejunum","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D007583","descriptor_name":"Jejunum","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D007583","descriptor_name":"Jejunum","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D009119","descriptor_name":"Muscle Contraction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009119","descriptor_name":"Muscle Contraction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009119","descriptor_name":"Muscle Contraction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009119","descriptor_name":"Muscle Contraction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013552","descriptor_name":"Swine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013552","descriptor_name":"Swine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013552","descriptor_name":"Swine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013552","descriptor_name":"Swine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1109/tbme.2023.3317400","is_oa":true,"landing_page_url":"https://doi.org/10.1109/tbme.2023.3317400","pdf_url":"https://ieeexplore.ieee.org/ielx7/10/4359967/10256040.pdf","source":{"id":"https://openalex.org/S5240358","display_name":"IEEE Transactions on Biomedical Engineering","issn_l":"0018-9294","issn":["0018-9294","1558-2531"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Biomedical Engineering","raw_type":"journal-article"},{"id":"pmid:37729575","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37729575","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE transactions on bio-medical engineering","raw_type":null}],"best_oa_location":{"id":"doi:10.1109/tbme.2023.3317400","is_oa":true,"landing_page_url":"https://doi.org/10.1109/tbme.2023.3317400","pdf_url":"https://ieeexplore.ieee.org/ielx7/10/4359967/10256040.pdf","source":{"id":"https://openalex.org/S5240358","display_name":"IEEE Transactions on Biomedical Engineering","issn_l":"0018-9294","issn":["0018-9294","1558-2531"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Biomedical Engineering","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320320774","display_name":"Royal Society Te Ap\u0101rangi","ror":"https://ror.org/04tajb587"},{"id":"https://openalex.org/F4320335369","display_name":"Marsden Fund","ror":null}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4386902930.pdf","grobid_xml":"https://content.openalex.org/works/W4386902930.grobid-xml"},"referenced_works_count":54,"referenced_works":["https://openalex.org/W1489595427","https://openalex.org/W1491829236","https://openalex.org/W1534467349","https://openalex.org/W1974246098","https://openalex.org/W1978361508","https://openalex.org/W1997917261","https://openalex.org/W1999837630","https://openalex.org/W2003089913","https://openalex.org/W2003272170","https://openalex.org/W2009635280","https://openalex.org/W2022170160","https://openalex.org/W2029523151","https://openalex.org/W2033977007","https://openalex.org/W2037660862","https://openalex.org/W2040251647","https://openalex.org/W2043849573","https://openalex.org/W2051788696","https://openalex.org/W2052413517","https://openalex.org/W2058411818","https://openalex.org/W2062015671","https://openalex.org/W2071094055","https://openalex.org/W2074914898","https://openalex.org/W2104093933","https://openalex.org/W2113591291","https://openalex.org/W2119258055","https://openalex.org/W2144356090","https://openalex.org/W2149388915","https://openalex.org/W2152852254","https://openalex.org/W2160831363","https://openalex.org/W2184441011","https://openalex.org/W2282980327","https://openalex.org/W2285206522","https://openalex.org/W2318516020","https://openalex.org/W2346608628","https://openalex.org/W2419380873","https://openalex.org/W2523424611","https://openalex.org/W2779553076","https://openalex.org/W2790675055","https://openalex.org/W2797233076","https://openalex.org/W2803823517","https://openalex.org/W2888002365","https://openalex.org/W2904005582","https://openalex.org/W2969169157","https://openalex.org/W2981451622","https://openalex.org/W3016136018","https://openalex.org/W4200388776","https://openalex.org/W4249973010","https://openalex.org/W4283701282","https://openalex.org/W4289638668","https://openalex.org/W4301182629","https://openalex.org/W4306403779","https://openalex.org/W4321446664","https://openalex.org/W4360770965","https://openalex.org/W6695516873"],"related_works":["https://openalex.org/W4387497383","https://openalex.org/W3183948672","https://openalex.org/W3173606202","https://openalex.org/W3110381201","https://openalex.org/W2948807893","https://openalex.org/W2899084033","https://openalex.org/W2778153218","https://openalex.org/W2758277628","https://openalex.org/W1531601525","https://openalex.org/W2376275270"],"abstract_inverted_index":{"OBJECTIVE:":[0],"Compromised":[1],"bowel":[2,256],"function":[3],"is":[4],"associated":[5],"with":[6,165,174,178,274],"a":[7,94],"range":[8],"of":[9,28,42,52,115,162,284],"motility":[10,23,247],"disorders":[11,257],"such":[12],"as":[13],"post-operative":[14],"ileus":[15],"and":[16,34,86,108,146,192,230,258],"chronic":[17],"intestinal":[18,106],"pseudo-obstruction.":[19],"Disordered":[20],"or":[21],"weak":[22],"compromise":[24],"the":[25,40,49,53,78,87,105,111,156,160,181,231,237,241,281,290,294],"efficient":[26],"movement":[27],"luminal":[29],"contents":[30],"necessary":[31],"for":[32,133,255],"digestion":[33],"nutrient":[35],"absorption.":[36],"This":[37,278],"study":[38,279],"investigated":[39],"potential":[41,134,254],"high-energy":[43],"pacing":[44,116,150,163,203,220,228,249,265,291],"to":[45,131,154,227,236,245,288],"enhance":[46,246],"contractions":[47,100,139,224,269],"in":[48,77,79,183,225,272,293],"proximal":[50],"jejunum":[51,82],"small":[54,295],"intestine.":[55,242,296],"METHODS:":[56],"Pacing":[57],"pulse":[58,276],"parameters":[59,117],"(pulse-width:":[60],"100":[61,190],"ms,":[62,64,66,212],"200":[63],"400":[65,193,211],"pulse-amplitude:":[67],"4":[68],"mA,":[69,71,208],"6":[70],"8":[72],"mA)":[73],"were":[74,91,101,126,140],"systematically":[75],"varied":[76],"vivo":[80],"porcine":[81],"(n":[83],"=":[84,206,210],"7)":[85],"induced":[88,142,221],"contractile":[89,119,184,232],"responses":[90],"evaluated":[92,147],"using":[93],"video":[95,285],"mapping":[96,286],"system.":[97],"Localized":[98],"segmental":[99,223,268],"quantified":[102],"by":[103,168],"measuring":[104],"diameter":[107,166],"thereby":[109],"computing":[110],"strain.":[112],"The":[113,243],"impact":[114],"on":[118,128,240],"strain":[120,233],"was":[121,186,216,234],"investigated.":[122],"Finally,":[123],"histological":[124],"studies":[125],"conducted":[127],"paced":[129],"tissue":[130,135,198],"assess":[132],"damage.":[136],"RESULTS:":[137],"Segmental":[138],"successfully":[141],"at":[143,159],"all":[144],"pulse-settings":[145],"across":[148],"67":[149],"sessions.":[151],"In":[152],"response":[153,171,185,226,292],"pacing,":[155],"intestine":[157,264],"segment":[158],"site":[161],"contracted,":[164],"reduced":[167],"6-18%.":[169],"Contractile":[170],"significantly":[172],"increased":[173],"increasing":[175,179,275],"pulse-amplitude.":[176],"However,":[177],"pulse-width,":[180],"increase":[182,271],"significant":[187],"only":[188],"between":[189],"ms":[191],"ms.":[194],"Histology":[195],"showed":[196],"no":[197],"damage":[199],"occurred":[200],"when":[201],"maximal":[202],"energy":[204,238],"(pulse-amplitude":[205],"4-8":[207],"pulse-width":[209],"5":[213],"minute":[214],"duration)":[215],"applied.":[217],"CONCLUSION:":[218],"High-energy":[219],"periodic":[222],"pulses":[229],"proportional":[235],"applied":[239],"ability":[244],"through":[248],"may":[250],"hold":[251],"promising":[252],"therapeutic":[253],"awaits":[259],"clinical":[260],"translation.":[261],"SIGNIFICANCE:":[262],"Small":[263],"elicits":[266],"localized":[267],"which":[270],"magnitude":[273],"settings.":[277],"marks":[280],"first":[282],"adaptation":[283],"techniques":[287],"track":[289]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1}],"updated_date":"2026-03-27T05:58:40.876381","created_date":"2025-10-10T00:00:00"}