{"id":"https://openalex.org/W4381329044","doi":"https://doi.org/10.1109/tbme.2023.3287514","title":"Using Bayesian Neural Networks to Select Features and Compute Credible Intervals for Personalized Survival Prediction","display_name":"Using Bayesian Neural Networks to Select Features and Compute Credible Intervals for Personalized Survival Prediction","publication_year":2023,"publication_date":"2023-06-20","ids":{"openalex":"https://openalex.org/W4381329044","doi":"https://doi.org/10.1109/tbme.2023.3287514","pmid":"https://pubmed.ncbi.nlm.nih.gov/37339045"},"language":"en","primary_location":{"id":"doi:10.1109/tbme.2023.3287514","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tbme.2023.3287514","pdf_url":null,"source":{"id":"https://openalex.org/S5240358","display_name":"IEEE Transactions on Biomedical Engineering","issn_l":"0018-9294","issn":["0018-9294","1558-2531"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Biomedical Engineering","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://repository.lsu.edu/eecs_pubs/2234","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5019118865","display_name":"Shi-ang Qi","orcid":"https://orcid.org/0000-0002-4319-5501"},"institutions":[{"id":"https://openalex.org/I154425047","display_name":"University of Alberta","ror":"https://ror.org/0160cpw27","country_code":"CA","type":"education","lineage":["https://openalex.org/I154425047"]}],"countries":["CA"],"is_corresponding":true,"raw_author_name":"Shi-ang Qi","raw_affiliation_strings":["Department of Computing Science, University of Alberta, Canada"],"affiliations":[{"raw_affiliation_string":"Department of Computing Science, University of Alberta, Canada","institution_ids":["https://openalex.org/I154425047"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101527505","display_name":"Neeraj Kumar","orcid":"https://orcid.org/0000-0002-3221-3831"},"institutions":[{"id":"https://openalex.org/I154425047","display_name":"University of Alberta","ror":"https://ror.org/0160cpw27","country_code":"CA","type":"education","lineage":["https://openalex.org/I154425047"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Neeraj Kumar","raw_affiliation_strings":["Department of Computing Science, University of Alberta, Canada","Alberta Machine Intelligence Institute, Canada"],"affiliations":[{"raw_affiliation_string":"Department of Computing Science, University of Alberta, Canada","institution_ids":["https://openalex.org/I154425047"]},{"raw_affiliation_string":"Alberta Machine Intelligence Institute, Canada","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032491679","display_name":"Ruchika Verma","orcid":"https://orcid.org/0000-0003-4870-128X"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ruchika Verma","raw_affiliation_strings":["Alberta Machine Intelligence Institute, Canada"],"affiliations":[{"raw_affiliation_string":"Alberta Machine Intelligence Institute, Canada","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045467934","display_name":"Jianyi Xu","orcid":"https://orcid.org/0000-0003-4552-8194"},"institutions":[{"id":"https://openalex.org/I126859394","display_name":"Alberta Health Services","ror":"https://ror.org/02nt5es71","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I126859394"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Jian-Yi Xu","raw_affiliation_strings":["Alberta&#x0027;s Tomorrow Project, Cancer Care Alberta, Alberta Health Services, Canada"],"affiliations":[{"raw_affiliation_string":"Alberta&#x0027;s Tomorrow Project, Cancer Care Alberta, Alberta Health Services, Canada","institution_ids":["https://openalex.org/I126859394"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000904916","display_name":"Grace Shen\u2010Tu","orcid":"https://orcid.org/0000-0001-7104-8683"},"institutions":[{"id":"https://openalex.org/I126859394","display_name":"Alberta Health Services","ror":"https://ror.org/02nt5es71","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I126859394"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Grace Shen-Tu","raw_affiliation_strings":["Alberta&#x0027;s Tomorrow Project, Cancer Care Alberta, Alberta Health Services, Canada"],"affiliations":[{"raw_affiliation_string":"Alberta&#x0027;s Tomorrow Project, Cancer Care Alberta, Alberta Health Services, Canada","institution_ids":["https://openalex.org/I126859394"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5027200864","display_name":"Russell Greiner","orcid":"https://orcid.org/0000-0001-8327-934X"},"institutions":[{"id":"https://openalex.org/I154425047","display_name":"University of Alberta","ror":"https://ror.org/0160cpw27","country_code":"CA","type":"education","lineage":["https://openalex.org/I154425047"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Russell Greiner","raw_affiliation_strings":["Department of Computing Science, University of Alberta, Canada","Alberta Machine Intelligence Institute, Canada"],"affiliations":[{"raw_affiliation_string":"Department of Computing Science, University of Alberta, Canada","institution_ids":["https://openalex.org/I154425047"]},{"raw_affiliation_string":"Alberta Machine Intelligence Institute, Canada","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5019118865"],"corresponding_institution_ids":["https://openalex.org/I154425047"],"apc_list":null,"apc_paid":null,"fwci":1.3917,"has_fulltext":false,"cited_by_count":8,"citation_normalized_percentile":{"value":0.84683287,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":99},"biblio":{"volume":"70","issue":"12","first_page":"3389","last_page":"3400"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13702","display_name":"Machine Learning in Healthcare","score":0.9987000226974487,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T13702","display_name":"Machine Learning in Healthcare","score":0.9987000226974487,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12422","display_name":"Radiomics and Machine Learning in Medical Imaging","score":0.9926000237464905,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10552","display_name":"Colorectal Cancer Screening and Detection","score":0.9836999773979187,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/feature-selection","display_name":"Feature selection","score":0.6489498615264893},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6309078931808472},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.6298542022705078},{"id":"https://openalex.org/keywords/feature","display_name":"Feature (linguistics)","score":0.6258493065834045},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.6059069633483887},{"id":"https://openalex.org/keywords/prior-probability","display_name":"Prior probability","score":0.5943254828453064},{"id":"https://openalex.org/keywords/bayesian-probability","display_name":"Bayesian probability","score":0.5629340410232544},{"id":"https://openalex.org/keywords/artificial-neural-network","display_name":"Artificial neural network","score":0.5497947335243225},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.44497573375701904},{"id":"https://openalex.org/keywords/bayesian-inference","display_name":"Bayesian inference","score":0.4150317311286926}],"concepts":[{"id":"https://openalex.org/C148483581","wikidata":"https://www.wikidata.org/wiki/Q446488","display_name":"Feature selection","level":2,"score":0.6489498615264893},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6309078931808472},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.6298542022705078},{"id":"https://openalex.org/C2776401178","wikidata":"https://www.wikidata.org/wiki/Q12050496","display_name":"Feature (linguistics)","level":2,"score":0.6258493065834045},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.6059069633483887},{"id":"https://openalex.org/C177769412","wikidata":"https://www.wikidata.org/wiki/Q278090","display_name":"Prior probability","level":3,"score":0.5943254828453064},{"id":"https://openalex.org/C107673813","wikidata":"https://www.wikidata.org/wiki/Q812534","display_name":"Bayesian probability","level":2,"score":0.5629340410232544},{"id":"https://openalex.org/C50644808","wikidata":"https://www.wikidata.org/wiki/Q192776","display_name":"Artificial neural network","level":2,"score":0.5497947335243225},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.44497573375701904},{"id":"https://openalex.org/C160234255","wikidata":"https://www.wikidata.org/wiki/Q812535","display_name":"Bayesian inference","level":3,"score":0.4150317311286926},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D001499","descriptor_name":"Bayes Theorem","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001499","descriptor_name":"Bayes Theorem","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001499","descriptor_name":"Bayes Theorem","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001499","descriptor_name":"Bayes Theorem","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001499","descriptor_name":"Bayes Theorem","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D035501","descriptor_name":"Uncertainty","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D035501","descriptor_name":"Uncertainty","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D035501","descriptor_name":"Uncertainty","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D035501","descriptor_name":"Uncertainty","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D035501","descriptor_name":"Uncertainty","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1109/tbme.2023.3287514","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tbme.2023.3287514","pdf_url":null,"source":{"id":"https://openalex.org/S5240358","display_name":"IEEE Transactions on Biomedical Engineering","issn_l":"0018-9294","issn":["0018-9294","1558-2531"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Biomedical Engineering","raw_type":"journal-article"},{"id":"pmid:37339045","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37339045","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE transactions on bio-medical engineering","raw_type":null},{"id":"pmh:oai:repository.lsu.edu:eecs_pubs-3236","is_oa":true,"landing_page_url":"https://repository.lsu.edu/eecs_pubs/2234","pdf_url":null,"source":{"id":"https://openalex.org/S4210169993","display_name":"Civil War Book Review","issn_l":"1528-6592","issn":["1528-6592"],"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/P4310315936","host_organization_name":"Louisiana State University","host_organization_lineage":["https://openalex.org/P4310315936"],"host_organization_lineage_names":["Louisiana State University"],"type":"journal"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Faculty Publications","raw_type":"text"}],"best_oa_location":{"id":"pmh:oai:repository.lsu.edu:eecs_pubs-3236","is_oa":true,"landing_page_url":"https://repository.lsu.edu/eecs_pubs/2234","pdf_url":null,"source":{"id":"https://openalex.org/S4210169993","display_name":"Civil War Book Review","issn_l":"1528-6592","issn":["1528-6592"],"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/P4310315936","host_organization_name":"Louisiana State University","host_organization_lineage":["https://openalex.org/P4310315936"],"host_organization_lineage_names":["Louisiana State University"],"type":"journal"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Faculty Publications","raw_type":"text"},"sustainable_development_goals":[{"score":0.7599999904632568,"display_name":"Peace, Justice and strong institutions","id":"https://metadata.un.org/sdg/16"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320314212","display_name":"Alberta Machine Intelligence Institute","ror":null},{"id":"https://openalex.org/F4320334593","display_name":"Natural Sciences and Engineering Research Council of Canada","ror":"https://ror.org/01h531d29"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":59,"referenced_works":["https://openalex.org/W1580282541","https://openalex.org/W1965026065","https://openalex.org/W1975900555","https://openalex.org/W1983413936","https://openalex.org/W1993434718","https://openalex.org/W1999974018","https://openalex.org/W2052825782","https://openalex.org/W2098749003","https://openalex.org/W2110992644","https://openalex.org/W2122825543","https://openalex.org/W2128360321","https://openalex.org/W2128552449","https://openalex.org/W2131987814","https://openalex.org/W2135046866","https://openalex.org/W2143426320","https://openalex.org/W2149746825","https://openalex.org/W2153491803","https://openalex.org/W2157076315","https://openalex.org/W2163183941","https://openalex.org/W2164826114","https://openalex.org/W2167205245","https://openalex.org/W2297134449","https://openalex.org/W2324805613","https://openalex.org/W2482566988","https://openalex.org/W2753919178","https://openalex.org/W2783134495","https://openalex.org/W2887934021","https://openalex.org/W2908045944","https://openalex.org/W2911964244","https://openalex.org/W2928673187","https://openalex.org/W2945236379","https://openalex.org/W2946927056","https://openalex.org/W2965152073","https://openalex.org/W2982580298","https://openalex.org/W2989979377","https://openalex.org/W2998216295","https://openalex.org/W2998441233","https://openalex.org/W3004574683","https://openalex.org/W3012396268","https://openalex.org/W3038272954","https://openalex.org/W3123284220","https://openalex.org/W3147894994","https://openalex.org/W4220759284","https://openalex.org/W4234911918","https://openalex.org/W4236640235","https://openalex.org/W4245958676","https://openalex.org/W4311914214","https://openalex.org/W6638836233","https://openalex.org/W6684488266","https://openalex.org/W6738806959","https://openalex.org/W6747288244","https://openalex.org/W6750869745","https://openalex.org/W6756633684","https://openalex.org/W6770098668","https://openalex.org/W6774758870","https://openalex.org/W6842259822","https://openalex.org/W6846103915","https://openalex.org/W6863924446","https://openalex.org/W7066667914"],"related_works":["https://openalex.org/W2562263695","https://openalex.org/W2135187896","https://openalex.org/W2147201983","https://openalex.org/W2015518264","https://openalex.org/W2795035211","https://openalex.org/W2160108762","https://openalex.org/W4386564352","https://openalex.org/W2952668426","https://openalex.org/W2164129707","https://openalex.org/W4292122269"],"abstract_inverted_index":{"An":[0],"Individual":[1],"Survival":[2],"Distribution":[3],"(ISD)":[4],"models":[5,18,45,49],"a":[6,71,132,218],"patient's":[7],"personalized":[8,26],"survival":[9,27,79,168,201],"probability":[10],"at":[11],"all":[12],"future":[13],"time":[14,31],"points.":[15],"Previously,":[16],"ISD":[17,44,73,226],"have":[19],"been":[20],"shown":[21],"to":[22,32,35,51,94,103,116,130,137],"produce":[23],"accurate":[24,78],"and":[25,59,107,148,161,186],"estimates":[28,80],"(for":[29],"example,":[30],"relapse":[33],"or":[34],"death)":[36],"in":[37,86,121,182,213],"several":[38],"clinical":[39,66,151,193,214],"applications.":[40],"However,":[41],"off-the-shelf":[42],"neural-network-based":[43],"are":[46],"usually":[47],"opaque":[48],"due":[50],"their":[52,64],"limited":[53],"support":[54,104],"for":[55,114,170,190],"meaningful":[56,159,188],"feature":[57,105,139,180],"selection":[58,106],"uncertainty":[60,85,222],"estimation,":[61,89],"which":[62,90],"hinders":[63],"wide":[65],"adoption.":[67],"Here,":[68],"we":[69],"introduce":[70],"Bayesian-neural-network-based":[72],"(BNN-ISD)":[74],"model":[75,126],"that":[76,153,175,207],"produces":[77],"but":[81],"also":[82,198,205],"quantifies":[83],"the":[84,97,100,118,167,183,191,221,224],"model's":[87,119],"parameter":[88],"can":[91,156,211],"be":[92],"used":[93],"(1)":[95],"rank":[96],"importance":[98,181],"of":[99,135,166,220,223],"input":[101],"features":[102,160,189],"(2)":[108],"compute":[109,162],"credible":[110,164,209],"intervals":[111,165],"around":[112],"ISDs":[113],"clinicians":[115],"assess":[117],"confidence":[120],"its":[122],"prediction.":[123],"Our":[124],"BNN-ISD":[125,154],"utilized":[127],"sparsity-inducing":[128],"priors":[129],"learn":[131],"sparse":[133],"set":[134],"weights":[136],"enable":[138],"selection.":[140],"We":[141,173,204],"provide":[142],"empirical":[143],"evidence,":[144],"on":[145],"2":[146],"synthetic":[147,184],"3":[149],"real-world":[150,192],"datasets,":[152],"system":[155],"effectively":[157],"select":[158],"trustworthy":[163],"distribution":[169],"each":[171],"patient.":[172],"observed":[174],"our":[176],"approach":[177],"accurately":[178],"recovers":[179],"datasets":[185],"selects":[187],"data":[194],"as":[195],"well,":[196],"while":[197],"achieving":[199],"state-of-the-art":[200],"prediction":[202],"performance.":[203],"show":[206],"these":[208],"regions":[210],"aid":[212],"decision-making":[215],"by":[216],"providing":[217],"gauge":[219],"estimated":[225],"curves.":[227]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":1}],"updated_date":"2026-03-27T05:58:40.876381","created_date":"2025-10-10T00:00:00"}
