{"id":"https://openalex.org/W4282933418","doi":"https://doi.org/10.1109/tbme.2022.3177074","title":"Quantifying Rheumatoid Arthritis Disease Activity Using a Multimodal Sensing Knee Brace","display_name":"Quantifying Rheumatoid Arthritis Disease Activity Using a Multimodal Sensing Knee Brace","publication_year":2022,"publication_date":"2022-05-23","ids":{"openalex":"https://openalex.org/W4282933418","doi":"https://doi.org/10.1109/tbme.2022.3177074","pmid":"https://pubmed.ncbi.nlm.nih.gov/35604995"},"language":"en","primary_location":{"id":"doi:10.1109/tbme.2022.3177074","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tbme.2022.3177074","pdf_url":null,"source":{"id":"https://openalex.org/S5240358","display_name":"IEEE Transactions on Biomedical Engineering","issn_l":"0018-9294","issn":["0018-9294","1558-2531"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Biomedical Engineering","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5015825469","display_name":"K. Richardson","orcid":"https://orcid.org/0000-0002-9683-0628"},"institutions":[{"id":"https://openalex.org/I130701444","display_name":"Georgia Institute of Technology","ror":"https://ror.org/01zkghx44","country_code":"US","type":"education","lineage":["https://openalex.org/I130701444"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Kristine L. Richardson","raw_affiliation_strings":["School of Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, GA, USA"],"raw_orcid":"https://orcid.org/0000-0002-9683-0628","affiliations":[{"raw_affiliation_string":"School of Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, GA, USA","institution_ids":["https://openalex.org/I130701444"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081642538","display_name":"Caitlin N. Teague","orcid":"https://orcid.org/0000-0002-3660-0724"},"institutions":[{"id":"https://openalex.org/I130701444","display_name":"Georgia Institute of Technology","ror":"https://ror.org/01zkghx44","country_code":"US","type":"education","lineage":["https://openalex.org/I130701444"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Caitlin N. Teague","raw_affiliation_strings":["School of Electrical and Computer Engineering, Georgia Institute of Technology, USA"],"raw_orcid":"https://orcid.org/0000-0002-3660-0724","affiliations":[{"raw_affiliation_string":"School of Electrical and Computer Engineering, Georgia Institute of Technology, USA","institution_ids":["https://openalex.org/I130701444"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065186117","display_name":"Samer Mabrouk","orcid":"https://orcid.org/0000-0001-9534-6319"},"institutions":[{"id":"https://openalex.org/I130701444","display_name":"Georgia Institute of Technology","ror":"https://ror.org/01zkghx44","country_code":"US","type":"education","lineage":["https://openalex.org/I130701444"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Samer Mabrouk","raw_affiliation_strings":["School of Electrical and Computer Engineering, Georgia Institute of Technology, USA"],"raw_orcid":"https://orcid.org/0000-0001-9534-6319","affiliations":[{"raw_affiliation_string":"School of Electrical and Computer Engineering, Georgia Institute of Technology, USA","institution_ids":["https://openalex.org/I130701444"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084874403","display_name":"Brandi N. Nevius","orcid":"https://orcid.org/0000-0003-2549-2032"},"institutions":[{"id":"https://openalex.org/I130701444","display_name":"Georgia Institute of Technology","ror":"https://ror.org/01zkghx44","country_code":"US","type":"education","lineage":["https://openalex.org/I130701444"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Brandi N. Nevius","raw_affiliation_strings":["School of Mechanical Engineering, Georgia Institute of Technology, USA"],"raw_orcid":"https://orcid.org/0000-0003-2549-2032","affiliations":[{"raw_affiliation_string":"School of Mechanical Engineering, Georgia Institute of Technology, USA","institution_ids":["https://openalex.org/I130701444"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016304738","display_name":"G\u00f6ktu\u011f C. \u00d6zmen","orcid":"https://orcid.org/0000-0002-5930-6819"},"institutions":[{"id":"https://openalex.org/I130701444","display_name":"Georgia Institute of Technology","ror":"https://ror.org/01zkghx44","country_code":"US","type":"education","lineage":["https://openalex.org/I130701444"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Goktug C. Ozmen","raw_affiliation_strings":["School of Electrical and Computer Engineering, Georgia Institute of Technology, USA"],"raw_orcid":"https://orcid.org/0000-0002-5930-6819","affiliations":[{"raw_affiliation_string":"School of Electrical and Computer Engineering, Georgia Institute of Technology, USA","institution_ids":["https://openalex.org/I130701444"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049540755","display_name":"Rachel S. Graham","orcid":null},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rachel S. Graham","raw_affiliation_strings":["Center for Immunology and Department of Pediatrics and the Department of Otolaryngology-Head and Neck Surgery, University of Minnesota, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Immunology and Department of Pediatrics and the Department of Otolaryngology-Head and Neck Surgery, University of Minnesota, USA","institution_ids":["https://openalex.org/I130238516"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060447332","display_name":"Daniel P. Zachs","orcid":"https://orcid.org/0000-0002-9615-3233"},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Daniel P. Zachs","raw_affiliation_strings":["Department of Otolaryngology-Head and Neck Surgery and the Department of Biomedical Engineering, University of Minnesota, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Otolaryngology-Head and Neck Surgery and the Department of Biomedical Engineering, University of Minnesota, USA","institution_ids":["https://openalex.org/I130238516"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080905829","display_name":"Adam Tuma","orcid":"https://orcid.org/0000-0001-7868-8392"},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Adam Tuma","raw_affiliation_strings":["Department of Biomedical Engineering, University of Minnesota, Minneapolis, MN, USA"],"raw_orcid":"https://orcid.org/0000-0001-7868-8392","affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, University of Minnesota, Minneapolis, MN, USA","institution_ids":["https://openalex.org/I130238516"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091723554","display_name":"Erik Peterson","orcid":"https://orcid.org/0000-0002-2033-007X"},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Erik J. Peterson","raw_affiliation_strings":["Division of Rheumatic and Autoimmune Diseases, University of Minnesota, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Rheumatic and Autoimmune Diseases, University of Minnesota, USA","institution_ids":["https://openalex.org/I130238516"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090096213","display_name":"Hubert H. Lim","orcid":"https://orcid.org/0000-0001-5653-9679"},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hubert H. Lim","raw_affiliation_strings":["Department of Otolaryngology-Head and Neck Surgery, Department of Biomedical Engineering, and the Institute for Translational Neuroscience, University of Minnesota, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Otolaryngology-Head and Neck Surgery, Department of Biomedical Engineering, and the Institute for Translational Neuroscience, University of Minnesota, USA","institution_ids":["https://openalex.org/I130238516"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5076927036","display_name":"Omer T. Inan","orcid":"https://orcid.org/0000-0002-7952-1794"},"institutions":[{"id":"https://openalex.org/I130701444","display_name":"Georgia Institute of Technology","ror":"https://ror.org/01zkghx44","country_code":"US","type":"education","lineage":["https://openalex.org/I130701444"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Omer T. Inan","raw_affiliation_strings":["School of Electrical and Computer Engineering and the School of Biomedical Engineering, Georgia Institute of Technology, USA"],"raw_orcid":"https://orcid.org/0000-0002-7952-1794","affiliations":[{"raw_affiliation_string":"School of Electrical and Computer Engineering and the School of Biomedical Engineering, Georgia Institute of Technology, USA","institution_ids":["https://openalex.org/I130701444"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":11,"corresponding_author_ids":["https://openalex.org/A5015825469"],"corresponding_institution_ids":["https://openalex.org/I130701444"],"apc_list":null,"apc_paid":null,"fwci":2.322,"has_fulltext":false,"cited_by_count":15,"citation_normalized_percentile":{"value":0.88732436,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":99},"biblio":{"volume":"69","issue":"12","first_page":"3772","last_page":"3783"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10200","display_name":"Rheumatoid Arthritis Research and Therapies","score":0.5009999871253967,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10200","display_name":"Rheumatoid Arthritis Research and Therapies","score":0.5009999871253967,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11255","display_name":"Microfluidic and Bio-sensing Technologies","score":0.0812000036239624,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11778","display_name":"Electrical and Bioimpedance Tomography","score":0.06920000165700912,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/rheumatoid-arthritis","display_name":"Rheumatoid arthritis","score":0.7882297039031982},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.7391538619995117},{"id":"https://openalex.org/keywords/brace","display_name":"Brace","score":0.5897975564002991},{"id":"https://openalex.org/keywords/receiver-operating-characteristic","display_name":"Receiver operating characteristic","score":0.5670939683914185},{"id":"https://openalex.org/keywords/linear-discriminant-analysis","display_name":"Linear discriminant analysis","score":0.48090195655822754},{"id":"https://openalex.org/keywords/physical-therapy","display_name":"Physical therapy","score":0.4602815508842468},{"id":"https://openalex.org/keywords/erythrocyte-sedimentation-rate","display_name":"Erythrocyte sedimentation rate","score":0.45143112540245056},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.40401020646095276},{"id":"https://openalex.org/keywords/physical-medicine-and-rehabilitation","display_name":"Physical medicine and rehabilitation","score":0.36011186242103577},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.17051228880882263},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.14810502529144287}],"concepts":[{"id":"https://openalex.org/C2777575956","wikidata":"https://www.wikidata.org/wiki/Q187255","display_name":"Rheumatoid arthritis","level":2,"score":0.7882297039031982},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7391538619995117},{"id":"https://openalex.org/C2779793219","wikidata":"https://www.wikidata.org/wiki/Q2662870","display_name":"Brace","level":2,"score":0.5897975564002991},{"id":"https://openalex.org/C58471807","wikidata":"https://www.wikidata.org/wiki/Q327120","display_name":"Receiver operating characteristic","level":2,"score":0.5670939683914185},{"id":"https://openalex.org/C69738355","wikidata":"https://www.wikidata.org/wiki/Q1228929","display_name":"Linear discriminant analysis","level":2,"score":0.48090195655822754},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.4602815508842468},{"id":"https://openalex.org/C2778143017","wikidata":"https://www.wikidata.org/wiki/Q111208","display_name":"Erythrocyte sedimentation rate","level":2,"score":0.45143112540245056},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.40401020646095276},{"id":"https://openalex.org/C99508421","wikidata":"https://www.wikidata.org/wiki/Q2678675","display_name":"Physical medicine and rehabilitation","level":1,"score":0.36011186242103577},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.17051228880882263},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.14810502529144287},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C78519656","wikidata":"https://www.wikidata.org/wiki/Q101333","display_name":"Mechanical engineering","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D001172","descriptor_name":"Arthritis, Rheumatoid","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D001172","descriptor_name":"Arthritis, Rheumatoid","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D001172","descriptor_name":"Arthritis, Rheumatoid","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D001172","descriptor_name":"Arthritis, Rheumatoid","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D001172","descriptor_name":"Arthritis, Rheumatoid","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D001172","descriptor_name":"Arthritis, Rheumatoid","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D001799","descriptor_name":"Blood Sedimentation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001799","descriptor_name":"Blood Sedimentation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001799","descriptor_name":"Blood Sedimentation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012372","descriptor_name":"ROC Curve","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012372","descriptor_name":"ROC Curve","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012372","descriptor_name":"ROC Curve","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012720","descriptor_name":"Severity of Illness Index","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012720","descriptor_name":"Severity of Illness Index","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012720","descriptor_name":"Severity of Illness Index","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018501","descriptor_name":"Antirheumatic Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D018501","descriptor_name":"Antirheumatic Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D018501","descriptor_name":"Antirheumatic Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1109/tbme.2022.3177074","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tbme.2022.3177074","pdf_url":null,"source":{"id":"https://openalex.org/S5240358","display_name":"IEEE Transactions on Biomedical Engineering","issn_l":"0018-9294","issn":["0018-9294","1558-2531"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Biomedical Engineering","raw_type":"journal-article"},{"id":"pmid:35604995","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35604995","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE transactions on bio-medical engineering","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.6399999856948853,"display_name":"Reduced inequalities","id":"https://metadata.un.org/sdg/10"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":37,"referenced_works":["https://openalex.org/W111301790","https://openalex.org/W205374009","https://openalex.org/W1596381381","https://openalex.org/W1980276147","https://openalex.org/W1994455711","https://openalex.org/W2004304522","https://openalex.org/W2011031966","https://openalex.org/W2021056136","https://openalex.org/W2066573398","https://openalex.org/W2074438676","https://openalex.org/W2093977673","https://openalex.org/W2098279921","https://openalex.org/W2102118942","https://openalex.org/W2110826367","https://openalex.org/W2118745544","https://openalex.org/W2145699228","https://openalex.org/W2161584352","https://openalex.org/W2164020604","https://openalex.org/W2261130562","https://openalex.org/W2335966725","https://openalex.org/W2552483823","https://openalex.org/W2561948967","https://openalex.org/W2752361399","https://openalex.org/W2805636409","https://openalex.org/W2807591703","https://openalex.org/W2901023217","https://openalex.org/W2914157689","https://openalex.org/W2960333166","https://openalex.org/W2965146093","https://openalex.org/W2988345887","https://openalex.org/W3025531568","https://openalex.org/W3091526655","https://openalex.org/W3108803027","https://openalex.org/W3143544829","https://openalex.org/W4301423781","https://openalex.org/W6604480570","https://openalex.org/W6608471404"],"related_works":["https://openalex.org/W2990021029","https://openalex.org/W1854890619","https://openalex.org/W2397852956","https://openalex.org/W2551499063","https://openalex.org/W24994384","https://openalex.org/W2165717376","https://openalex.org/W2415397981","https://openalex.org/W2256044857","https://openalex.org/W2148068646","https://openalex.org/W2738716281"],"abstract_inverted_index":{"OBJECTIVE:":[0],"Rheumatoid":[1],"arthritis":[2],"(RA)":[3],"is":[4,35],"a":[5,95,121,152,259],"chronic":[6],"inflammatory":[7],"syndrome":[8],"that":[9,253],"features":[10],"painful":[11],"and":[12,24,44,59,78,107,149,210],"destructive":[13],"joint":[14,28,64],"disease.":[15],"Aggressive":[16],"disease-modifying":[17],"treatment":[18,33],"can":[19,254],"result":[20],"in":[21,66,101,186],"reduced":[22],"symptoms":[23],"protection":[25],"from":[26,83,114],"irreversible":[27],"damage;":[29],"however,":[30],"assessment":[31],"of":[32,42,91,174,200,204,258],"efficacy":[34],"currently":[36],"based":[37],"largely":[38],"on":[39],"subjective":[40],"measures":[41],"patient":[43],"physician":[45],"impressions.":[46],"In":[47],"this":[48,52],"work,":[49],"we":[50,179],"address":[51],"compelling":[53],"need":[54],"to":[55,127,132,182,212,227,241],"provide":[56],"an":[57,165,198,208],"accurate":[58],"quantitative":[60],"capability":[61],"for":[62,218],"monitoring":[63,246],"health":[65],"patients":[67,85,205],"with":[68,86,104,109,164,197],"RA.":[69],"METHODS:":[70],"Joint":[71],"acoustic":[72],"emissions":[73],"(JAEs),":[74],"electrical":[75],"bioimpedance":[76],"(EBI),":[77],"kinematics":[79],"were":[80,118,180],"measured":[81],"noninvasively":[82],"11":[84],"RA":[87,229,243],"over":[88],"the":[89,133,168,187,214,225,239],"course":[90],"three":[92],"weeks":[93],"using":[94,146,157,232],"custom":[96],"multimodal":[97],"sensing":[98,116],"brace,":[99],"resulting":[100],"49":[102],"visits":[103],"JAE":[105],"recordings":[106],"43":[108],"EBI":[110],"recordings.":[111],"Features":[112],"derived":[113],"all":[115],"modalities":[117],"fed":[119],"into":[120,151],"linear":[122],"discriminant":[123],"analysis":[124],"(LDA)":[125],"model":[126],"predict":[128],"disease":[129,135,188,230,244],"activity":[130,136,189,231,245],"according":[131],"validated":[134],"index":[137],"(the":[138],"DAS28-ESR).":[139],"Erythrocyte":[140],"sedimentation":[141],"rate":[142],"(ESR)":[143],"was":[144,162],"predicted":[145,163],"ridge":[147],"regression":[148],"classified":[150],"high":[153],"or":[154],"low":[155],"class":[156],"LDA.":[158],"RESULTS:":[159],"DAS28-ESR":[160],"level":[161,196],"area":[166],"under":[167],"receiver":[169],"operating":[170],"characteristic":[171],"curve":[172],"(AUC)":[173],"0.82.":[175],"With":[176],"JAEs":[177],"alone,":[178],"able":[181],"track":[183],"intrasubject":[184],"differences":[185],"score":[190],"as":[191,193],"well":[192],"classify":[194],"ESR":[195],"AUC":[199],"0.93.":[201],"The":[202],"majority":[203],"reported":[206],"both":[207],"interest":[209],"ability":[211,226],"use":[213],"brace":[215],"at":[216],"home":[217],"longitudinal":[219],"monitoring.":[220],"CONCLUSION:":[221],"This":[222,236],"work":[223],"demonstrates":[224],"detect":[228],"noninvasive":[233],"sensing.":[234],"SIGNIFICANCE:":[235],"system":[237],"has":[238],"potential":[240],"improve":[242],"by":[247],"giving":[248],"treating":[249],"clinicians":[250],"objective":[251],"data":[252],"be":[255],"acquired":[256],"independent":[257],"face-to-face":[260],"clinic":[261],"visit.":[262]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":7},{"year":2022,"cited_by_count":2}],"updated_date":"2026-04-29T09:16:38.111599","created_date":"2025-10-10T00:00:00"}
