{"id":"https://openalex.org/W4206708348","doi":"https://doi.org/10.1109/tbme.2022.3143542","title":"Electroporation Microchip With Integrated Conducting Polymer Electrode Array for Highly Sensitive Impedance Measurement","display_name":"Electroporation Microchip With Integrated Conducting Polymer Electrode Array for Highly Sensitive Impedance Measurement","publication_year":2022,"publication_date":"2022-01-18","ids":{"openalex":"https://openalex.org/W4206708348","doi":"https://doi.org/10.1109/tbme.2022.3143542","pmid":"https://pubmed.ncbi.nlm.nih.gov/35041593"},"language":"en","primary_location":{"id":"doi:10.1109/tbme.2022.3143542","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tbme.2022.3143542","pdf_url":null,"source":{"id":"https://openalex.org/S5240358","display_name":"IEEE Transactions on Biomedical Engineering","issn_l":"0018-9294","issn":["0018-9294","1558-2531"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Biomedical Engineering","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Gerwin Dijk","orcid":"https://orcid.org/0000-0003-2482-9828"},"institutions":[{"id":"https://openalex.org/I3019848993","display_name":"Mines Saint-\u00c9tienne","ror":"https://ror.org/05a1dws80","country_code":"FR","type":"education","lineage":["https://openalex.org/I203339264","https://openalex.org/I205703379","https://openalex.org/I3019848993"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Gerwin Dijk","raw_affiliation_strings":["Department of Bioelectronics, Mines Saint-Etienne, Centre CMP, France"],"raw_orcid":"https://orcid.org/0000-0003-2482-9828","affiliations":[{"raw_affiliation_string":"Department of Bioelectronics, Mines Saint-Etienne, Centre CMP, France","institution_ids":["https://openalex.org/I3019848993"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Romanos Poulkouras","orcid":null},"institutions":[{"id":"https://openalex.org/I3019848993","display_name":"Mines Saint-\u00c9tienne","ror":"https://ror.org/05a1dws80","country_code":"FR","type":"education","lineage":["https://openalex.org/I203339264","https://openalex.org/I205703379","https://openalex.org/I3019848993"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Romanos Poulkouras","raw_affiliation_strings":["Department of Bioelectronics, Mines Saint-Etienne, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Bioelectronics, Mines Saint-Etienne, France","institution_ids":["https://openalex.org/I3019848993"]}]},{"author_position":"last","author":{"id":null,"display_name":"Rodney P. O'Connor","orcid":"https://orcid.org/0000-0002-3916-3101"},"institutions":[{"id":"https://openalex.org/I3019848993","display_name":"Mines Saint-\u00c9tienne","ror":"https://ror.org/05a1dws80","country_code":"FR","type":"education","lineage":["https://openalex.org/I203339264","https://openalex.org/I205703379","https://openalex.org/I3019848993"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Rodney P. O'Connor","raw_affiliation_strings":["Department of Bioelectronics, Mines Saint-Etienne, Gardanne, France"],"raw_orcid":"https://orcid.org/0000-0002-3916-3101","affiliations":[{"raw_affiliation_string":"Department of Bioelectronics, Mines Saint-Etienne, Gardanne, France","institution_ids":["https://openalex.org/I3019848993"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I3019848993"],"apc_list":null,"apc_paid":null,"fwci":0.716,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":{"value":0.66877493,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":96},"biblio":{"volume":"69","issue":"7","first_page":"2363","last_page":"2369"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11455","display_name":"Microbial Inactivation Methods","score":0.9825000166893005,"subfield":{"id":"https://openalex.org/subfields/1305","display_name":"Biotechnology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11455","display_name":"Microbial Inactivation Methods","score":0.9825000166893005,"subfield":{"id":"https://openalex.org/subfields/1305","display_name":"Biotechnology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11255","display_name":"Microfluidic and Bio-sensing Technologies","score":0.003599999938160181,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11778","display_name":"Electrical and Bioimpedance Tomography","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/electroporation","display_name":"Electroporation","score":0.7929999828338623},{"id":"https://openalex.org/keywords/electrode","display_name":"Electrode","score":0.6122999787330627},{"id":"https://openalex.org/keywords/electrical-impedance","display_name":"Electrical impedance","score":0.5443999767303467},{"id":"https://openalex.org/keywords/conductive-polymer","display_name":"Conductive polymer","score":0.5011000037193298},{"id":"https://openalex.org/keywords/electrical-conductor","display_name":"Electrical conductor","score":0.39809998869895935},{"id":"https://openalex.org/keywords/electrode-array","display_name":"Electrode array","score":0.37070000171661377}],"concepts":[{"id":"https://openalex.org/C186852380","wikidata":"https://www.wikidata.org/wiki/Q1142521","display_name":"Electroporation","level":3,"score":0.7929999828338623},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.7566999793052673},{"id":"https://openalex.org/C17525397","wikidata":"https://www.wikidata.org/wiki/Q176140","display_name":"Electrode","level":2,"score":0.6122999787330627},{"id":"https://openalex.org/C17829176","wikidata":"https://www.wikidata.org/wiki/Q179043","display_name":"Electrical impedance","level":2,"score":0.5443999767303467},{"id":"https://openalex.org/C49040817","wikidata":"https://www.wikidata.org/wiki/Q193091","display_name":"Optoelectronics","level":1,"score":0.5187000036239624},{"id":"https://openalex.org/C133495861","wikidata":"https://www.wikidata.org/wiki/Q412798","display_name":"Conductive polymer","level":3,"score":0.5011000037193298},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.4207000136375427},{"id":"https://openalex.org/C202374169","wikidata":"https://www.wikidata.org/wiki/Q124291","display_name":"Electrical conductor","level":2,"score":0.39809998869895935},{"id":"https://openalex.org/C97562148","wikidata":"https://www.wikidata.org/wiki/Q5357989","display_name":"Electrode array","level":3,"score":0.37070000171661377},{"id":"https://openalex.org/C24326235","wikidata":"https://www.wikidata.org/wiki/Q126095","display_name":"Electronic engineering","level":1,"score":0.36489999294281006},{"id":"https://openalex.org/C172066009","wikidata":"https://www.wikidata.org/wiki/Q5463955","display_name":"Focused Impedance Measurement","level":3,"score":0.34549999237060547},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.3447999954223633},{"id":"https://openalex.org/C521977710","wikidata":"https://www.wikidata.org/wiki/Q81163","display_name":"Polymer","level":2,"score":0.3156999945640564},{"id":"https://openalex.org/C160756335","wikidata":"https://www.wikidata.org/wiki/Q669391","display_name":"Biosensor","level":2,"score":0.27810001373291016},{"id":"https://openalex.org/C119599485","wikidata":"https://www.wikidata.org/wiki/Q43035","display_name":"Electrical engineering","level":1,"score":0.26809999346733093}],"mesh":[{"descriptor_ui":"D004566","descriptor_name":"Electrodes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004566","descriptor_name":"Electrodes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004566","descriptor_name":"Electrodes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011108","descriptor_name":"Polymers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011108","descriptor_name":"Polymers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011108","descriptor_name":"Polymers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017097","descriptor_name":"Electric Impedance","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017097","descriptor_name":"Electric Impedance","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017097","descriptor_name":"Electric Impedance","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018274","descriptor_name":"Electroporation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018274","descriptor_name":"Electroporation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018274","descriptor_name":"Electroporation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1109/tbme.2022.3143542","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tbme.2022.3143542","pdf_url":null,"source":{"id":"https://openalex.org/S5240358","display_name":"IEEE Transactions on Biomedical Engineering","issn_l":"0018-9294","issn":["0018-9294","1558-2531"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Biomedical Engineering","raw_type":"journal-article"},{"id":"pmid:35041593","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35041593","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE transactions on bio-medical engineering","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G4633495473","display_name":null,"funder_award_id":"ANR-18-CE19-0029","funder_id":"https://openalex.org/F4320320883","funder_display_name":"Agence Nationale de la Recherche"}],"funders":[{"id":"https://openalex.org/F4320320883","display_name":"Agence Nationale de la Recherche","ror":"https://ror.org/00rbzpz17"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":36,"referenced_works":["https://openalex.org/W205196499","https://openalex.org/W1920588034","https://openalex.org/W1967093606","https://openalex.org/W2002319275","https://openalex.org/W2020653182","https://openalex.org/W2024579314","https://openalex.org/W2036464893","https://openalex.org/W2092137760","https://openalex.org/W2138045682","https://openalex.org/W2179643578","https://openalex.org/W2268394529","https://openalex.org/W2277311694","https://openalex.org/W2294443631","https://openalex.org/W2319910816","https://openalex.org/W2333894357","https://openalex.org/W2499744106","https://openalex.org/W2521075624","https://openalex.org/W2615043514","https://openalex.org/W2805267068","https://openalex.org/W2891581025","https://openalex.org/W2900614456","https://openalex.org/W2901575037","https://openalex.org/W2921241300","https://openalex.org/W2922419853","https://openalex.org/W2939397021","https://openalex.org/W2981759119","https://openalex.org/W3006545178","https://openalex.org/W3012839541","https://openalex.org/W3032834306","https://openalex.org/W3036797212","https://openalex.org/W3095818160","https://openalex.org/W3095953146","https://openalex.org/W3111242453","https://openalex.org/W3199647505","https://openalex.org/W4232240465","https://openalex.org/W4246218456"],"related_works":[],"abstract_inverted_index":{"OBJECTIVE:":[0],"Monitoring":[1],"of":[2,25,64,109,139,154,185],"impedance":[3,37,73,129,155],"changes":[4,130,156],"during":[5,106],"electroporation-based":[6],"treatments":[7],"can":[8,32,171],"be":[9,33,172],"used":[10,173],"to":[11,123,174],"study":[12,175],"the":[13,26,30,41,47,90,92,98,107,137,152],"biological":[14],"response":[15],"and":[16,35,85,114,144,164,178,188],"provide":[17],"feedback":[18],"regarding":[19],"treatment":[20,115,180],"progression.":[21],"However,":[22],"seamless":[23],"integration":[24],"sensing":[27,38,68,86,93],"electrodes":[28,39,69,94],"with":[29,82,97,116,157],"setup":[31],"challenging":[34],"high":[36,161],"limit":[40],"recording":[42],"sensitivity":[43],"as":[44,46,59,61],"well":[45,60],"spatial":[48,162],"resolution.":[49],"Here,":[50],"we":[51],"present":[52],"an":[53,62],"all-in-one":[54],"microchip":[55],"containing":[56],"stimulation":[57,84],"electrodes,":[58,121,125,159],"array":[63],"low":[65],"impedance,":[66,91],"micro-scale":[67,158],"for":[70,182],"highly":[71],"sensitive":[72],"monitoring.":[74],"METHODS:":[75],"An":[76],"in":[77,131],"vitro":[78],"platform":[79],"is":[80,104],"fabricated":[81],"integrated":[83],"electrodes.":[87],"To":[88],"reduce":[89],"are":[95],"coated":[96],"conducting":[99],"polymer":[100],"PEDOT:PSS.":[101],"The":[102],"performance":[103],"studied":[105],"growth":[108],"a":[110,132,140],"confluent":[111,141],"cell":[112,142],"layer":[113,143],"electrical":[117,146],"pulses.":[118],"RESULTS:":[119],"Coated":[120],"compared":[122],"uncoated":[124],"show":[126],"more":[127],"pronounced":[128],"broader":[133],"frequency":[134],"range":[135],"throughout":[136],"formation":[138],"after":[145],"treatment.":[147],"CONCLUSION:":[148],"PEDOT:PSS":[149],"coatings":[150],"enhance":[151],"monitoring":[153,169],"enabling":[160],"resolution":[163],"increased":[165],"sensitivity.":[166],"SIGNIFICANCE:":[167],"Such":[168],"systems":[170],"electroporation":[176],"dynamics":[177],"monitor":[179],"progression":[181],"better":[183],"understanding":[184],"underlying":[186],"mechanisms":[187],"improved":[189],"outcomes.":[190]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":2}],"updated_date":"2026-04-28T14:05:53.105641","created_date":"2022-01-25T00:00:00"}