{"id":"https://openalex.org/W3205272500","doi":"https://doi.org/10.1109/tbme.2021.3121170","title":"Modeling Patient-Specific Desaturation Patterns in Sleep Apnea","display_name":"Modeling Patient-Specific Desaturation Patterns in Sleep Apnea","publication_year":2021,"publication_date":"2021-10-20","ids":{"openalex":"https://openalex.org/W3205272500","doi":"https://doi.org/10.1109/tbme.2021.3121170","mag":"3205272500","pmid":"https://pubmed.ncbi.nlm.nih.gov/34665719"},"language":"en","primary_location":{"id":"doi:10.1109/tbme.2021.3121170","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tbme.2021.3121170","pdf_url":null,"source":{"id":"https://openalex.org/S5240358","display_name":"IEEE Transactions on Biomedical Engineering","issn_l":"0018-9294","issn":["0018-9294","1558-2531"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Biomedical Engineering","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://hal.science/hal-03477355/document","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5102723881","display_name":"Gustavo Guerrero","orcid":"https://orcid.org/0000-0003-3436-0656"},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210105651","display_name":"Laboratoire Traitement du Signal et de l'Image","ror":"https://ror.org/01f1amm71","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I154526488","https://openalex.org/I4210105651","https://openalex.org/I4210105774","https://openalex.org/I56067802"]},{"id":"https://openalex.org/I56067802","display_name":"Universit\u00e9 de Rennes","ror":"https://ror.org/015m7wh34","country_code":"FR","type":"education","lineage":["https://openalex.org/I56067802"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Gustavo Guerrero","raw_affiliation_strings":["Univ Rennes, Inserm, LTSI - UMR 1099, France"],"raw_orcid":"https://orcid.org/0000-0003-3436-0656","affiliations":[{"raw_affiliation_string":"Univ Rennes, Inserm, LTSI - UMR 1099, France","institution_ids":["https://openalex.org/I4210105651","https://openalex.org/I56067802","https://openalex.org/I154526488"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017502569","display_name":"Virginie Le Rolle","orcid":"https://orcid.org/0000-0003-1068-5587"},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210105651","display_name":"Laboratoire Traitement du Signal et de l'Image","ror":"https://ror.org/01f1amm71","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I154526488","https://openalex.org/I4210105651","https://openalex.org/I4210105774","https://openalex.org/I56067802"]},{"id":"https://openalex.org/I56067802","display_name":"Universit\u00e9 de Rennes","ror":"https://ror.org/015m7wh34","country_code":"FR","type":"education","lineage":["https://openalex.org/I56067802"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Virginie Le Rolle","raw_affiliation_strings":["Univ Rennes, Inserm, LTSI - UMR 1099, Rennes, France"],"raw_orcid":"https://orcid.org/0000-0003-1068-5587","affiliations":[{"raw_affiliation_string":"Univ Rennes, Inserm, LTSI - UMR 1099, Rennes, France","institution_ids":["https://openalex.org/I56067802","https://openalex.org/I154526488","https://openalex.org/I4210105651"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008051675","display_name":"Corinne Loiodice","orcid":null},"institutions":[{"id":"https://openalex.org/I4210151160","display_name":"Grenoble Institute of Neurosciences","ror":"https://ror.org/04as3rk94","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I2738703131","https://openalex.org/I4210151160","https://openalex.org/I899635006"]},{"id":"https://openalex.org/I899635006","display_name":"Universit\u00e9 Grenoble Alpes","ror":"https://ror.org/02rx3b187","country_code":"FR","type":"education","lineage":["https://openalex.org/I899635006"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Corinne Loiodice","raw_affiliation_strings":["Department of Physiology and Sleep, Grenoble Alps University Hospital, France","HP2 laboratory, Grenoble Alpes University, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology and Sleep, Grenoble Alps University Hospital, France","institution_ids":["https://openalex.org/I4210151160","https://openalex.org/I899635006"]},{"raw_affiliation_string":"HP2 laboratory, Grenoble Alpes University, France","institution_ids":["https://openalex.org/I899635006"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113721891","display_name":"Amel Amblard","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Amel Amblard","raw_affiliation_strings":["Microport, Sorin CRM SAS, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Microport, Sorin CRM SAS, France","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067706451","display_name":"Jean\u2010Louis P\u00e9pin","orcid":"https://orcid.org/0000-0003-3832-2358"},"institutions":[{"id":"https://openalex.org/I4210151160","display_name":"Grenoble Institute of Neurosciences","ror":"https://ror.org/04as3rk94","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I2738703131","https://openalex.org/I4210151160","https://openalex.org/I899635006"]},{"id":"https://openalex.org/I899635006","display_name":"Universit\u00e9 Grenoble Alpes","ror":"https://ror.org/02rx3b187","country_code":"FR","type":"education","lineage":["https://openalex.org/I899635006"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Jean-Louis Pepin","raw_affiliation_strings":["Department of Physiology and Sleep, Grenoble Alps University Hospital, France","HP2 laboratory, Grenoble Alpes University, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology and Sleep, Grenoble Alps University Hospital, France","institution_ids":["https://openalex.org/I4210151160","https://openalex.org/I899635006"]},{"raw_affiliation_string":"HP2 laboratory, Grenoble Alpes University, France","institution_ids":["https://openalex.org/I899635006"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5006420548","display_name":"Alfredo Hern\u00e1ndez","orcid":"https://orcid.org/0000-0003-0765-2311"},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210105651","display_name":"Laboratoire Traitement du Signal et de l'Image","ror":"https://ror.org/01f1amm71","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I154526488","https://openalex.org/I4210105651","https://openalex.org/I4210105774","https://openalex.org/I56067802"]},{"id":"https://openalex.org/I56067802","display_name":"Universit\u00e9 de Rennes","ror":"https://ror.org/015m7wh34","country_code":"FR","type":"education","lineage":["https://openalex.org/I56067802"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Alfredo Hernandez","raw_affiliation_strings":["Univ Rennes, Inserm, LTSI - UMR 1099, France"],"raw_orcid":"https://orcid.org/0000-0003-0765-2311","affiliations":[{"raw_affiliation_string":"Univ Rennes, Inserm, LTSI - UMR 1099, France","institution_ids":["https://openalex.org/I4210105651","https://openalex.org/I56067802","https://openalex.org/I154526488"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5102723881"],"corresponding_institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210105651","https://openalex.org/I56067802"],"apc_list":null,"apc_paid":null,"fwci":1.0916,"has_fulltext":true,"cited_by_count":9,"citation_normalized_percentile":{"value":0.76876667,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":98},"biblio":{"volume":"69","issue":"4","first_page":"1502","last_page":"1511"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10234","display_name":"Obstructive Sleep Apnea Research","score":0.9775000214576721,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10234","display_name":"Obstructive Sleep Apnea Research","score":0.9775000214576721,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11456","display_name":"Neuroscience of respiration and sleep","score":0.0066999997943639755,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12419","display_name":"Phonocardiography and Auscultation Techniques","score":0.0026000000070780516,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/apnea","display_name":"Apnea","score":0.6674208045005798},{"id":"https://openalex.org/keywords/obstructive-sleep-apnea","display_name":"Obstructive sleep apnea","score":0.6554749011993408},{"id":"https://openalex.org/keywords/sleep-apnea","display_name":"Sleep apnea","score":0.6538792848587036},{"id":"https://openalex.org/keywords/breathing","display_name":"Breathing","score":0.5400939583778381},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.5310165286064148},{"id":"https://openalex.org/keywords/polysomnography","display_name":"Polysomnography","score":0.4293361306190491},{"id":"https://openalex.org/keywords/respiratory-system","display_name":"Respiratory system","score":0.4237830936908722},{"id":"https://openalex.org/keywords/hypoxemia","display_name":"Hypoxemia","score":0.412466824054718},{"id":"https://openalex.org/keywords/cardiology","display_name":"Cardiology","score":0.3369676470756531},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.31483834981918335},{"id":"https://openalex.org/keywords/anesthesia","display_name":"Anesthesia","score":0.20006027817726135}],"concepts":[{"id":"https://openalex.org/C2781326671","wikidata":"https://www.wikidata.org/wiki/Q754424","display_name":"Apnea","level":2,"score":0.6674208045005798},{"id":"https://openalex.org/C2776006263","wikidata":"https://www.wikidata.org/wiki/Q16606552","display_name":"Obstructive sleep apnea","level":2,"score":0.6554749011993408},{"id":"https://openalex.org/C2777935920","wikidata":"https://www.wikidata.org/wiki/Q213600","display_name":"Sleep apnea","level":2,"score":0.6538792848587036},{"id":"https://openalex.org/C39300077","wikidata":"https://www.wikidata.org/wiki/Q9530","display_name":"Breathing","level":2,"score":0.5400939583778381},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5310165286064148},{"id":"https://openalex.org/C2778205975","wikidata":"https://www.wikidata.org/wiki/Q1754874","display_name":"Polysomnography","level":3,"score":0.4293361306190491},{"id":"https://openalex.org/C534529494","wikidata":"https://www.wikidata.org/wiki/Q7891","display_name":"Respiratory system","level":2,"score":0.4237830936908722},{"id":"https://openalex.org/C2776779939","wikidata":"https://www.wikidata.org/wiki/Q1479485","display_name":"Hypoxemia","level":2,"score":0.412466824054718},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.3369676470756531},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.31483834981918335},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.20006027817726135}],"mesh":[{"descriptor_ui":"D000402","descriptor_name":"Airway Obstruction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000402","descriptor_name":"Airway Obstruction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000402","descriptor_name":"Airway Obstruction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010100","descriptor_name":"Oxygen","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010100","descriptor_name":"Oxygen","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010100","descriptor_name":"Oxygen","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012891","descriptor_name":"Sleep Apnea Syndromes","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D012891","descriptor_name":"Sleep Apnea Syndromes","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D012891","descriptor_name":"Sleep Apnea Syndromes","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D020181","descriptor_name":"Sleep Apnea, Obstructive","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020181","descriptor_name":"Sleep Apnea, Obstructive","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020181","descriptor_name":"Sleep Apnea, Obstructive","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1109/tbme.2021.3121170","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tbme.2021.3121170","pdf_url":null,"source":{"id":"https://openalex.org/S5240358","display_name":"IEEE Transactions on Biomedical Engineering","issn_l":"0018-9294","issn":["0018-9294","1558-2531"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Biomedical Engineering","raw_type":"journal-article"},{"id":"pmid:34665719","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34665719","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE transactions on bio-medical engineering","raw_type":null},{"id":"pmh:oai:HAL:hal-03477355v1","is_oa":true,"landing_page_url":"https://hal.science/hal-03477355","pdf_url":"https://hal.science/hal-03477355/document","source":{"id":"https://openalex.org/S4406922466","display_name":"SPIRE - Sciences Po Institutional REpository","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"IEEE Transactions on Biomedical Engineering, 2022, 69 (4), pp.1502-1511. ⟨10.1109/TBME.2021.3121170⟩","raw_type":"Journal articles"}],"best_oa_location":{"id":"pmh:oai:HAL:hal-03477355v1","is_oa":true,"landing_page_url":"https://hal.science/hal-03477355","pdf_url":"https://hal.science/hal-03477355/document","source":{"id":"https://openalex.org/S4406922466","display_name":"SPIRE - Sciences Po Institutional REpository","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"IEEE Transactions on Biomedical Engineering, 2022, 69 (4), pp.1502-1511. ⟨10.1109/TBME.2021.3121170⟩","raw_type":"Journal articles"},"sustainable_development_goals":[{"score":0.6800000071525574,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"awards":[{"id":"https://openalex.org/G1015254069","display_name":null,"funder_award_id":"689260","funder_id":"https://openalex.org/F4320332999","funder_display_name":"Horizon 2020 Framework Programme"},{"id":"https://openalex.org/G1107922028","display_name":null,"funder_award_id":"689260","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G7842005466","display_name":null,"funder_award_id":"Horizon 2020","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"}],"funders":[{"id":"https://openalex.org/F4320320300","display_name":"European Commission","ror":"https://ror.org/00k4n6c32"},{"id":"https://openalex.org/F4320320883","display_name":"Agence Nationale de la Recherche","ror":"https://ror.org/00rbzpz17"},{"id":"https://openalex.org/F4320332999","display_name":"Horizon 2020 Framework Programme","ror":"https://ror.org/00k4n6c32"}],"has_content":{"pdf":true,"grobid_xml":false},"content_urls":{"pdf":"https://content.openalex.org/works/W3205272500.pdf"},"referenced_works_count":51,"referenced_works":["https://openalex.org/W160199887","https://openalex.org/W1495744869","https://openalex.org/W1539665155","https://openalex.org/W1595159159","https://openalex.org/W1869536595","https://openalex.org/W1937676694","https://openalex.org/W1955109585","https://openalex.org/W1983015960","https://openalex.org/W1984411235","https://openalex.org/W1986140275","https://openalex.org/W1987971958","https://openalex.org/W1988230234","https://openalex.org/W1990988256","https://openalex.org/W2009978651","https://openalex.org/W2011299162","https://openalex.org/W2025266810","https://openalex.org/W2035785221","https://openalex.org/W2041556185","https://openalex.org/W2047944367","https://openalex.org/W2055823359","https://openalex.org/W2063932231","https://openalex.org/W2065559543","https://openalex.org/W2073480258","https://openalex.org/W2082461190","https://openalex.org/W2088076735","https://openalex.org/W2100705435","https://openalex.org/W2118694673","https://openalex.org/W2123738710","https://openalex.org/W2150593711","https://openalex.org/W2157308124","https://openalex.org/W2164202083","https://openalex.org/W2169472392","https://openalex.org/W2170973387","https://openalex.org/W2171750868","https://openalex.org/W2237044322","https://openalex.org/W2336233631","https://openalex.org/W2343078689","https://openalex.org/W2441644746","https://openalex.org/W2528548673","https://openalex.org/W2736044217","https://openalex.org/W2781820551","https://openalex.org/W2783032176","https://openalex.org/W2806325492","https://openalex.org/W2896217346","https://openalex.org/W2903375700","https://openalex.org/W2912705897","https://openalex.org/W2941932723","https://openalex.org/W2959442417","https://openalex.org/W2964831380","https://openalex.org/W2982392564","https://openalex.org/W2995039925"],"related_works":["https://openalex.org/W2414695243","https://openalex.org/W2134690175","https://openalex.org/W2024486471","https://openalex.org/W2433826713","https://openalex.org/W1954877112","https://openalex.org/W2034929828","https://openalex.org/W2025499314","https://openalex.org/W2985785409","https://openalex.org/W1652857925","https://openalex.org/W2037309944"],"abstract_inverted_index":{"OBJECTIVE:":[0],"The":[1,112],"physiological":[2],"mechanisms":[3],"involved":[4],"in":[5,71,84],"cardio-respiratory":[6,36],"responses":[7],"to":[8,22,28,67,73,80,101,126],"sleep":[9,102],"apnea":[10,103,127],"events":[11],"are":[12],"not":[13],"yet":[14],"fully":[15],"elucidated.":[16],"A":[17],"model-based":[18,117],"approach":[19],"is":[20],"proposed":[21,39,113],"analyse":[23],"the":[24,68,75],"acute":[25],"desaturation":[26,123],"response":[27,79],"obstructive":[29,54,81],"apneas.":[30,82],"METHODS:":[31],"An":[32],"integrated":[33],"model":[34],"of":[35,52,77,94],"interactions":[37],"was":[38,65],"and":[40,104,115,135],"parameters":[41,70],"were":[42,107],"identified,":[43],"using":[44],"an":[45],"evolutionary":[46],"algorithm,":[47],"on":[48,121],"a":[49],"database":[50],"composed":[51],"107":[53],"apneas":[55],"acquired":[56],"from":[57],"10":[58],"patients":[59],"(HYPNOS":[60],"clinical":[61],"study).":[62],"Unsupervised":[63],"clustering":[64],"applied":[66],"identified":[69],"order":[72],"characterize":[74],"phenotype":[76],"each":[78],"RESULTS:":[83],"all":[85],"identifications":[86],"(median":[87],"RMSE":[88],"=":[89],"1.3892":[90],"%).":[91],"Two":[92],"clusters":[93],"parameters,":[95],"associated":[96],"with":[97,129],"different":[98],"dynamics":[99],"related":[100],"periodic":[105],"breathing":[106],"obtained.":[108],"CONCLUSION":[109],"AND":[110],"SIGNIFICANCE:":[111],"patient":[114],"event-specific":[116],"analysis":[118],"provides":[119],"understanding":[120],"specific":[122],"patterns,":[124],"consequent":[125],"events,":[128],"potential":[130],"applications":[131],"for":[132],"personalized":[133],"diagnosis":[134],"treatment.":[136]},"counts_by_year":[{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":3}],"updated_date":"2026-05-05T08:41:31.759640","created_date":"2025-10-10T00:00:00"}