{"id":"https://openalex.org/W3129293921","doi":"https://doi.org/10.1109/tbme.2021.3061998","title":"A Multifactorial Model of Multiple Sclerosis Gait and Its Changes Across Different Disability Levels","display_name":"A Multifactorial Model of Multiple Sclerosis Gait and Its Changes Across Different Disability Levels","publication_year":2021,"publication_date":"2021-02-24","ids":{"openalex":"https://openalex.org/W3129293921","doi":"https://doi.org/10.1109/tbme.2021.3061998","mag":"3129293921","pmid":"https://pubmed.ncbi.nlm.nih.gov/33625975"},"language":"en","primary_location":{"id":"doi:10.1109/tbme.2021.3061998","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tbme.2021.3061998","pdf_url":null,"source":{"id":"https://openalex.org/S5240358","display_name":"IEEE Transactions on Biomedical Engineering","issn_l":"0018-9294","issn":["0018-9294","1558-2531"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Biomedical Engineering","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://zenodo.org/record/5165205","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5066254195","display_name":"Lorenza Angelini","orcid":"https://orcid.org/0000-0002-4763-7717"},"institutions":[{"id":"https://openalex.org/I4210102902","display_name":"Sheffield Teaching Hospitals NHS Foundation Trust","ror":"https://ror.org/018hjpz25","country_code":"GB","type":"funder","lineage":["https://openalex.org/I4210102902"]},{"id":"https://openalex.org/I4210147861","display_name":"Insigneo","ror":"https://ror.org/04ve58z79","country_code":"GB","type":"education","lineage":["https://openalex.org/I4210147861"]},{"id":"https://openalex.org/I91136226","display_name":"University of Sheffield","ror":"https://ror.org/05krs5044","country_code":"GB","type":"education","lineage":["https://openalex.org/I91136226"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Lorenza Angelini","raw_affiliation_strings":["Department of Mechanical Engineering and the Insigneo Institute for in silico Medicine, University of Sheffield, Sheffield, U.K","National Institute for Health Research (NIHR) Sheffield Clinical Research Facility and the NIHR Sheffield Biomedical Research Centre, Sheffield, UK. B","Department of Neuroscience, the Sheffield Teaching Hospital NHS Foundation Trust, and the Sheffield Institute of Translational Neuroscience, Sheffield, UK","NIHR Sheffield Biomedical Research Centre, the Academic Department of Neuroscience, the Sheffield Teaching Hospital NHS Foundation Trust, and the Sheffield Institute of Translational Neuroscience, Sheffield, UK","Department of Mechanical Engineering and the Insigneo Institute for in silico Medicine, University of Sheffield, Sheffield, UK","Department of Neuroscience, and the Sheffield Teaching Hospital NHS Foundation Trust, Sheffield, UK"],"raw_orcid":"https://orcid.org/0000-0002-4763-7717","affiliations":[{"raw_affiliation_string":"Department of Mechanical Engineering and the Insigneo Institute for in silico Medicine, University of Sheffield, Sheffield, U.K","institution_ids":["https://openalex.org/I4210147861"]},{"raw_affiliation_string":"National Institute for Health Research (NIHR) Sheffield Clinical Research Facility and the NIHR Sheffield Biomedical Research Centre, Sheffield, UK. B","institution_ids":["https://openalex.org/I91136226"]},{"raw_affiliation_string":"Department of Neuroscience, the Sheffield Teaching Hospital NHS Foundation Trust, and the Sheffield Institute of Translational Neuroscience, Sheffield, UK","institution_ids":["https://openalex.org/I4210102902"]},{"raw_affiliation_string":"NIHR Sheffield Biomedical Research Centre, the Academic Department of Neuroscience, the Sheffield Teaching Hospital NHS Foundation Trust, and the Sheffield Institute of Translational Neuroscience, Sheffield, UK","institution_ids":["https://openalex.org/I4210102902"]},{"raw_affiliation_string":"Department of Mechanical Engineering and the Insigneo Institute for in silico Medicine, University of Sheffield, Sheffield, UK","institution_ids":["https://openalex.org/I4210147861","https://openalex.org/I91136226"]},{"raw_affiliation_string":"Department of Neuroscience, and the Sheffield Teaching Hospital NHS Foundation Trust, Sheffield, UK","institution_ids":["https://openalex.org/I4210102902"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066163857","display_name":"Ellen Buckley","orcid":"https://orcid.org/0000-0002-0968-6286"},"institutions":[{"id":"https://openalex.org/I4210102902","display_name":"Sheffield Teaching Hospitals NHS Foundation Trust","ror":"https://ror.org/018hjpz25","country_code":"GB","type":"funder","lineage":["https://openalex.org/I4210102902"]},{"id":"https://openalex.org/I4210147861","display_name":"Insigneo","ror":"https://ror.org/04ve58z79","country_code":"GB","type":"education","lineage":["https://openalex.org/I4210147861"]},{"id":"https://openalex.org/I91136226","display_name":"University of Sheffield","ror":"https://ror.org/05krs5044","country_code":"GB","type":"education","lineage":["https://openalex.org/I91136226"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Ellen Buckley","raw_affiliation_strings":["Department of Mechanical Engineering and the Insigneo Institute for in silico Medicine, University of Sheffield, U.K","National Institute for Health Research (NIHR) Sheffield Clinical Research Facility and the NIHR Sheffield Biomedical Research Centre, Sheffield, UK. B","NIHR Sheffield Biomedical Research Centre, the Academic Department of Neuroscience, the Sheffield Teaching Hospital NHS Foundation Trust, and the Sheffield Institute of Translational Neuroscience, Sheffield, UK","Department of Neuroscience, and the Sheffield Teaching Hospital NHS Foundation Trust, Sheffield, UK","Department of Mechanical Engineering and the Insigneo Institute for in silico Medicine, University of Sheffield, Sheffield, UK","Department of Neuroscience, the Sheffield Teaching Hospital NHS Foundation Trust, and the Sheffield Institute of Translational Neuroscience, Sheffield, UK"],"raw_orcid":"https://orcid.org/0000-0002-0968-6286","affiliations":[{"raw_affiliation_string":"Department of Mechanical Engineering and the Insigneo Institute for in silico Medicine, University of Sheffield, U.K","institution_ids":["https://openalex.org/I4210147861"]},{"raw_affiliation_string":"National Institute for Health Research (NIHR) Sheffield Clinical Research Facility and the NIHR Sheffield Biomedical Research Centre, Sheffield, UK. B","institution_ids":["https://openalex.org/I91136226"]},{"raw_affiliation_string":"NIHR Sheffield Biomedical Research Centre, the Academic Department of Neuroscience, the Sheffield Teaching Hospital NHS Foundation Trust, and the Sheffield Institute of Translational Neuroscience, Sheffield, UK","institution_ids":["https://openalex.org/I4210102902"]},{"raw_affiliation_string":"Department of Neuroscience, and the Sheffield Teaching Hospital NHS Foundation Trust, Sheffield, UK","institution_ids":["https://openalex.org/I4210102902"]},{"raw_affiliation_string":"Department of Mechanical Engineering and the Insigneo Institute for in silico Medicine, University of Sheffield, Sheffield, UK","institution_ids":["https://openalex.org/I4210147861","https://openalex.org/I91136226"]},{"raw_affiliation_string":"Department of Neuroscience, the Sheffield Teaching Hospital NHS Foundation Trust, and the Sheffield Institute of Translational Neuroscience, Sheffield, UK","institution_ids":["https://openalex.org/I4210102902"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081479707","display_name":"Tecla Bonci","orcid":"https://orcid.org/0000-0002-8255-4730"},"institutions":[{"id":"https://openalex.org/I4210102902","display_name":"Sheffield Teaching Hospitals NHS Foundation Trust","ror":"https://ror.org/018hjpz25","country_code":"GB","type":"funder","lineage":["https://openalex.org/I4210102902"]},{"id":"https://openalex.org/I4210147861","display_name":"Insigneo","ror":"https://ror.org/04ve58z79","country_code":"GB","type":"education","lineage":["https://openalex.org/I4210147861"]},{"id":"https://openalex.org/I91136226","display_name":"University of Sheffield","ror":"https://ror.org/05krs5044","country_code":"GB","type":"education","lineage":["https://openalex.org/I91136226"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Tecla Bonci","raw_affiliation_strings":["Department of Mechanical Engineering and the Insigneo Institute for in silico Medicine, University of Sheffield, U.K","NIHR Sheffield Biomedical Research Centre, the Academic Department of Neuroscience, the Sheffield Teaching Hospital NHS Foundation Trust, and the Sheffield Institute of Translational Neuroscience, Sheffield, UK","Department of Neuroscience, and the Sheffield Teaching Hospital NHS Foundation Trust, Sheffield, UK","Department of Mechanical Engineering and the Insigneo Institute for in silico Medicine, University of Sheffield, Sheffield, UK","Department of Neuroscience, the Sheffield Teaching Hospital NHS Foundation Trust, and the Sheffield Institute of Translational Neuroscience, Sheffield, UK","National Institute for Health Research (NIHR) Sheffield Clinical Research Facility and the NIHR Sheffield Biomedical Research Centre, Sheffield, UK. B"],"raw_orcid":"https://orcid.org/0000-0002-8255-4730","affiliations":[{"raw_affiliation_string":"Department of Mechanical Engineering and the Insigneo Institute for in silico Medicine, University of Sheffield, U.K","institution_ids":["https://openalex.org/I4210147861"]},{"raw_affiliation_string":"NIHR Sheffield Biomedical Research Centre, the Academic Department of Neuroscience, the Sheffield Teaching Hospital NHS Foundation Trust, and the Sheffield Institute of Translational Neuroscience, Sheffield, UK","institution_ids":["https://openalex.org/I4210102902"]},{"raw_affiliation_string":"Department of Neuroscience, and the Sheffield Teaching Hospital NHS Foundation Trust, Sheffield, UK","institution_ids":["https://openalex.org/I4210102902"]},{"raw_affiliation_string":"Department of Mechanical Engineering and the Insigneo Institute for in silico Medicine, University of Sheffield, Sheffield, UK","institution_ids":["https://openalex.org/I4210147861","https://openalex.org/I91136226"]},{"raw_affiliation_string":"Department of Neuroscience, the Sheffield Teaching Hospital NHS Foundation Trust, and the Sheffield Institute of Translational Neuroscience, Sheffield, UK","institution_ids":["https://openalex.org/I4210102902"]},{"raw_affiliation_string":"National Institute for Health Research (NIHR) Sheffield Clinical Research Facility and the NIHR Sheffield Biomedical Research Centre, Sheffield, UK. B","institution_ids":["https://openalex.org/I91136226"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041487948","display_name":"Alexandra Radford","orcid":null},"institutions":[{"id":"https://openalex.org/I34931013","display_name":"National Institute for Health Research","ror":"https://ror.org/0187kwz08","country_code":"GB","type":"government","lineage":["https://openalex.org/I34931013"]},{"id":"https://openalex.org/I4210102902","display_name":"Sheffield Teaching Hospitals NHS Foundation Trust","ror":"https://ror.org/018hjpz25","country_code":"GB","type":"funder","lineage":["https://openalex.org/I4210102902"]},{"id":"https://openalex.org/I4210147861","display_name":"Insigneo","ror":"https://ror.org/04ve58z79","country_code":"GB","type":"education","lineage":["https://openalex.org/I4210147861"]},{"id":"https://openalex.org/I91136226","display_name":"University of Sheffield","ror":"https://ror.org/05krs5044","country_code":"GB","type":"education","lineage":["https://openalex.org/I91136226"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Alexandra Radford","raw_affiliation_strings":["National Institute for Health Research (NIHR) Sheffield Clinical Research Facility and the, NIHR Sheffield Biomedical Research Centre, U.K","Department of Neuroscience, and the Sheffield Teaching Hospital NHS Foundation Trust, Sheffield, UK","Department of Neuroscience, the Sheffield Teaching Hospital NHS Foundation Trust, and the Sheffield Institute of Translational Neuroscience, Sheffield, UK","Department of Mechanical Engineering and the Insigneo Institute for in silico Medicine, University of Sheffield, Sheffield, UK","NIHR Sheffield Biomedical Research Centre, the Academic Department of Neuroscience, the Sheffield Teaching Hospital NHS Foundation Trust, and the Sheffield Institute of Translational Neuroscience, Sheffield, UK","National Institute for Health Research (NIHR) Sheffield Clinical Research Facility and the NIHR Sheffield Biomedical Research Centre, Sheffield, UK. B"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Institute for Health Research (NIHR) Sheffield Clinical Research Facility and the, NIHR Sheffield Biomedical Research Centre, U.K","institution_ids":["https://openalex.org/I34931013"]},{"raw_affiliation_string":"Department of Neuroscience, and the Sheffield Teaching Hospital NHS Foundation Trust, Sheffield, UK","institution_ids":["https://openalex.org/I4210102902"]},{"raw_affiliation_string":"Department of Neuroscience, the Sheffield Teaching Hospital NHS Foundation Trust, and the Sheffield Institute of Translational Neuroscience, Sheffield, UK","institution_ids":["https://openalex.org/I4210102902"]},{"raw_affiliation_string":"Department of Mechanical Engineering and the Insigneo Institute for in silico Medicine, University of Sheffield, Sheffield, UK","institution_ids":["https://openalex.org/I4210147861","https://openalex.org/I91136226"]},{"raw_affiliation_string":"NIHR Sheffield Biomedical Research Centre, the Academic Department of Neuroscience, the Sheffield Teaching Hospital NHS Foundation Trust, and the Sheffield Institute of Translational Neuroscience, Sheffield, UK","institution_ids":["https://openalex.org/I4210102902"]},{"raw_affiliation_string":"National Institute for Health Research (NIHR) Sheffield Clinical Research Facility and the NIHR Sheffield Biomedical Research Centre, Sheffield, UK. B","institution_ids":["https://openalex.org/I91136226"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000364062","display_name":"Basil Sharrack","orcid":"https://orcid.org/0000-0003-2406-6365"},"institutions":[{"id":"https://openalex.org/I4210102902","display_name":"Sheffield Teaching Hospitals NHS Foundation Trust","ror":"https://ror.org/018hjpz25","country_code":"GB","type":"funder","lineage":["https://openalex.org/I4210102902"]},{"id":"https://openalex.org/I4210147861","display_name":"Insigneo","ror":"https://ror.org/04ve58z79","country_code":"GB","type":"education","lineage":["https://openalex.org/I4210147861"]},{"id":"https://openalex.org/I91136226","display_name":"University of Sheffield","ror":"https://ror.org/05krs5044","country_code":"GB","type":"education","lineage":["https://openalex.org/I91136226"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Basil Sharrack","raw_affiliation_strings":["NIHR Sheffield Biomedical Research Centre, the Academic Department of Neuroscience, the Sheffield Teaching Hospital NHS Foundation Trust, Sheffield Institute of Translational Neuroscience, U.K","NIHR Sheffield Biomedical Research Centre, the Academic Department of Neuroscience, the Sheffield Teaching Hospital NHS Foundation Trust, and the Sheffield Institute of Translational Neuroscience, Sheffield, UK","Department of Neuroscience, and the Sheffield Teaching Hospital NHS Foundation Trust, Sheffield, UK","Department of Neuroscience, the Sheffield Teaching Hospital NHS Foundation Trust, and the Sheffield Institute of Translational Neuroscience, Sheffield, UK","National Institute for Health Research (NIHR) Sheffield Clinical Research Facility and the NIHR Sheffield Biomedical Research Centre, Sheffield, UK. B","Department of Mechanical Engineering and the Insigneo Institute for in silico Medicine, University of Sheffield, Sheffield, UK"],"raw_orcid":"https://orcid.org/0000-0003-2406-6365","affiliations":[{"raw_affiliation_string":"NIHR Sheffield Biomedical Research Centre, the Academic Department of Neuroscience, the Sheffield Teaching Hospital NHS Foundation Trust, Sheffield Institute of Translational Neuroscience, U.K","institution_ids":["https://openalex.org/I4210102902"]},{"raw_affiliation_string":"NIHR Sheffield Biomedical Research Centre, the Academic Department of Neuroscience, the Sheffield Teaching Hospital NHS Foundation Trust, and the Sheffield Institute of Translational Neuroscience, Sheffield, UK","institution_ids":["https://openalex.org/I4210102902"]},{"raw_affiliation_string":"Department of Neuroscience, and the Sheffield Teaching Hospital NHS Foundation Trust, Sheffield, UK","institution_ids":["https://openalex.org/I4210102902"]},{"raw_affiliation_string":"Department of Neuroscience, the Sheffield Teaching Hospital NHS Foundation Trust, and the Sheffield Institute of Translational Neuroscience, Sheffield, UK","institution_ids":["https://openalex.org/I4210102902"]},{"raw_affiliation_string":"National Institute for Health Research (NIHR) Sheffield Clinical Research Facility and the NIHR Sheffield Biomedical Research Centre, Sheffield, UK. B","institution_ids":["https://openalex.org/I91136226"]},{"raw_affiliation_string":"Department of Mechanical Engineering and the Insigneo Institute for in silico Medicine, University of Sheffield, Sheffield, UK","institution_ids":["https://openalex.org/I4210147861","https://openalex.org/I91136226"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060851313","display_name":"David Paling","orcid":"https://orcid.org/0000-0003-4577-1821"},"institutions":[{"id":"https://openalex.org/I4210102902","display_name":"Sheffield Teaching Hospitals NHS Foundation Trust","ror":"https://ror.org/018hjpz25","country_code":"GB","type":"funder","lineage":["https://openalex.org/I4210102902"]},{"id":"https://openalex.org/I4210147861","display_name":"Insigneo","ror":"https://ror.org/04ve58z79","country_code":"GB","type":"education","lineage":["https://openalex.org/I4210147861"]},{"id":"https://openalex.org/I91136226","display_name":"University of Sheffield","ror":"https://ror.org/05krs5044","country_code":"GB","type":"education","lineage":["https://openalex.org/I91136226"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"David Paling","raw_affiliation_strings":["Academic Department of Neuroscience, the Sheffield Teaching Hospital NHS Foundation Trust, Sheffield Institute of Translational Neuroscience, U.K","Department of Neuroscience, the Sheffield Teaching Hospital NHS Foundation Trust, and the Sheffield Institute of Translational Neuroscience, Sheffield, UK","NIHR Sheffield Biomedical Research Centre, the Academic Department of Neuroscience, the Sheffield Teaching Hospital NHS Foundation Trust, and the Sheffield Institute of Translational Neuroscience, Sheffield, UK","Department of Mechanical Engineering and the Insigneo Institute for in silico Medicine, University of Sheffield, Sheffield, UK","Department of Neuroscience, and the Sheffield Teaching Hospital NHS Foundation Trust, Sheffield, UK","National Institute for Health Research (NIHR) Sheffield Clinical Research Facility and the NIHR Sheffield Biomedical Research Centre, Sheffield, UK. B"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Academic Department of Neuroscience, the Sheffield Teaching Hospital NHS Foundation Trust, Sheffield Institute of Translational Neuroscience, U.K","institution_ids":["https://openalex.org/I4210102902"]},{"raw_affiliation_string":"Department of Neuroscience, the Sheffield Teaching Hospital NHS Foundation Trust, and the Sheffield Institute of Translational Neuroscience, Sheffield, UK","institution_ids":["https://openalex.org/I4210102902"]},{"raw_affiliation_string":"NIHR Sheffield Biomedical Research Centre, the Academic Department of Neuroscience, the Sheffield Teaching Hospital NHS Foundation Trust, and the Sheffield Institute of Translational Neuroscience, Sheffield, UK","institution_ids":["https://openalex.org/I4210102902"]},{"raw_affiliation_string":"Department of Mechanical Engineering and the Insigneo Institute for in silico Medicine, University of Sheffield, Sheffield, UK","institution_ids":["https://openalex.org/I4210147861","https://openalex.org/I91136226"]},{"raw_affiliation_string":"Department of Neuroscience, and the Sheffield Teaching Hospital NHS Foundation Trust, Sheffield, UK","institution_ids":["https://openalex.org/I4210102902"]},{"raw_affiliation_string":"National Institute for Health Research (NIHR) Sheffield Clinical Research Facility and the NIHR Sheffield Biomedical Research Centre, Sheffield, UK. B","institution_ids":["https://openalex.org/I91136226"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001164694","display_name":"Krishnan Padmakumari Sivaraman Nair","orcid":"https://orcid.org/0000-0002-4004-2315"},"institutions":[{"id":"https://openalex.org/I4210102902","display_name":"Sheffield Teaching Hospitals NHS Foundation Trust","ror":"https://ror.org/018hjpz25","country_code":"GB","type":"funder","lineage":["https://openalex.org/I4210102902"]},{"id":"https://openalex.org/I4210147861","display_name":"Insigneo","ror":"https://ror.org/04ve58z79","country_code":"GB","type":"education","lineage":["https://openalex.org/I4210147861"]},{"id":"https://openalex.org/I91136226","display_name":"University of Sheffield","ror":"https://ror.org/05krs5044","country_code":"GB","type":"education","lineage":["https://openalex.org/I91136226"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Krishnan Padmakumari Sivaraman Nair","raw_affiliation_strings":["Insigneo Institute for in silico Medicine, University of Sheffield, Academic Department of Neuroscience, and the Sheffield Teaching Hospital NHS Foundation Trust, U.K","Department of Neuroscience, the Sheffield Teaching Hospital NHS Foundation Trust, and the Sheffield Institute of Translational Neuroscience, Sheffield, UK","NIHR Sheffield Biomedical Research Centre, the Academic Department of Neuroscience, the Sheffield Teaching Hospital NHS Foundation Trust, and the Sheffield Institute of Translational Neuroscience, Sheffield, UK","National Institute for Health Research (NIHR) Sheffield Clinical Research Facility and the NIHR Sheffield Biomedical Research Centre, Sheffield, UK. B","Department of Neuroscience, and the Sheffield Teaching Hospital NHS Foundation Trust, Sheffield, UK","Department of Mechanical Engineering and the Insigneo Institute for in silico Medicine, University of Sheffield, Sheffield, UK"],"raw_orcid":"https://orcid.org/0000-0002-4004-2315","affiliations":[{"raw_affiliation_string":"Insigneo Institute for in silico Medicine, University of Sheffield, Academic Department of Neuroscience, and the Sheffield Teaching Hospital NHS Foundation Trust, U.K","institution_ids":["https://openalex.org/I4210147861"]},{"raw_affiliation_string":"Department of Neuroscience, the Sheffield Teaching Hospital NHS Foundation Trust, and the Sheffield Institute of Translational Neuroscience, Sheffield, UK","institution_ids":["https://openalex.org/I4210102902"]},{"raw_affiliation_string":"NIHR Sheffield Biomedical Research Centre, the Academic Department of Neuroscience, the Sheffield Teaching Hospital NHS Foundation Trust, and the Sheffield Institute of Translational Neuroscience, Sheffield, UK","institution_ids":["https://openalex.org/I4210102902"]},{"raw_affiliation_string":"National Institute for Health Research (NIHR) Sheffield Clinical Research Facility and the NIHR Sheffield Biomedical Research Centre, Sheffield, UK. B","institution_ids":["https://openalex.org/I91136226"]},{"raw_affiliation_string":"Department of Neuroscience, and the Sheffield Teaching Hospital NHS Foundation Trust, Sheffield, UK","institution_ids":["https://openalex.org/I4210102902"]},{"raw_affiliation_string":"Department of Mechanical Engineering and the Insigneo Institute for in silico Medicine, University of Sheffield, Sheffield, UK","institution_ids":["https://openalex.org/I4210147861","https://openalex.org/I91136226"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5048644893","display_name":"Claudia Mazz\u00e0","orcid":"https://orcid.org/0000-0002-5215-1746"},"institutions":[{"id":"https://openalex.org/I4210102902","display_name":"Sheffield Teaching Hospitals NHS Foundation Trust","ror":"https://ror.org/018hjpz25","country_code":"GB","type":"funder","lineage":["https://openalex.org/I4210102902"]},{"id":"https://openalex.org/I4210147861","display_name":"Insigneo","ror":"https://ror.org/04ve58z79","country_code":"GB","type":"education","lineage":["https://openalex.org/I4210147861"]},{"id":"https://openalex.org/I91136226","display_name":"University of Sheffield","ror":"https://ror.org/05krs5044","country_code":"GB","type":"education","lineage":["https://openalex.org/I91136226"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Claudia Mazza","raw_affiliation_strings":["Department of Mechanical Engineering and the Insigneo Institute for in silico Medicine, University of Sheffield, U.K","NIHR Sheffield Biomedical Research Centre, the Academic Department of Neuroscience, the Sheffield Teaching Hospital NHS Foundation Trust, and the Sheffield Institute of Translational Neuroscience, Sheffield, UK","Department of Neuroscience, and the Sheffield Teaching Hospital NHS Foundation Trust, Sheffield, UK","Department of Neuroscience, the Sheffield Teaching Hospital NHS Foundation Trust, and the Sheffield Institute of Translational Neuroscience, Sheffield, UK","National Institute for Health Research (NIHR) Sheffield Clinical Research Facility and the NIHR Sheffield Biomedical Research Centre, Sheffield, UK. B","Department of Mechanical Engineering and the Insigneo Institute for in silico Medicine, University of Sheffield, Sheffield, UK"],"raw_orcid":"https://orcid.org/0000-0002-5215-1746","affiliations":[{"raw_affiliation_string":"Department of Mechanical Engineering and the Insigneo Institute for in silico Medicine, University of Sheffield, U.K","institution_ids":["https://openalex.org/I4210147861"]},{"raw_affiliation_string":"NIHR Sheffield Biomedical Research Centre, the Academic Department of Neuroscience, the Sheffield Teaching Hospital NHS Foundation Trust, and the Sheffield Institute of Translational Neuroscience, Sheffield, UK","institution_ids":["https://openalex.org/I4210102902"]},{"raw_affiliation_string":"Department of Neuroscience, and the Sheffield Teaching Hospital NHS Foundation Trust, Sheffield, UK","institution_ids":["https://openalex.org/I4210102902"]},{"raw_affiliation_string":"Department of Neuroscience, the Sheffield Teaching Hospital NHS Foundation Trust, and the Sheffield Institute of Translational Neuroscience, Sheffield, UK","institution_ids":["https://openalex.org/I4210102902"]},{"raw_affiliation_string":"National Institute for Health Research (NIHR) Sheffield Clinical Research Facility and the NIHR Sheffield Biomedical Research Centre, Sheffield, UK. B","institution_ids":["https://openalex.org/I91136226"]},{"raw_affiliation_string":"Department of Mechanical Engineering and the Insigneo Institute for in silico Medicine, University of Sheffield, Sheffield, UK","institution_ids":["https://openalex.org/I4210147861","https://openalex.org/I91136226"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5066254195"],"corresponding_institution_ids":["https://openalex.org/I4210102902","https://openalex.org/I4210147861","https://openalex.org/I91136226"],"apc_list":null,"apc_paid":null,"fwci":5.4219,"has_fulltext":true,"cited_by_count":20,"citation_normalized_percentile":{"value":0.95507074,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"68","issue":"11","first_page":"3196","last_page":"3204"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10114","display_name":"Balance, Gait, and Falls Prevention","score":0.7560999989509583,"subfield":{"id":"https://openalex.org/subfields/3612","display_name":"Physical Therapy, Sports Therapy and Rehabilitation"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10114","display_name":"Balance, Gait, and Falls Prevention","score":0.7560999989509583,"subfield":{"id":"https://openalex.org/subfields/3612","display_name":"Physical Therapy, Sports Therapy and Rehabilitation"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10137","display_name":"Multiple Sclerosis Research Studies","score":0.18160000443458557,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10855","display_name":"Amyotrophic Lateral Sclerosis Research","score":0.01510000042617321,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gait","display_name":"Gait","score":0.5981606841087341},{"id":"https://openalex.org/keywords/physical-medicine-and-rehabilitation","display_name":"Physical medicine and rehabilitation","score":0.5838944911956787},{"id":"https://openalex.org/keywords/multiple-sclerosis","display_name":"Multiple sclerosis","score":0.5781034827232361},{"id":"https://openalex.org/keywords/gait-analysis","display_name":"Gait analysis","score":0.4166823625564575},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.38740262389183044},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.34203243255615234}],"concepts":[{"id":"https://openalex.org/C151800584","wikidata":"https://www.wikidata.org/wiki/Q2370000","display_name":"Gait","level":2,"score":0.5981606841087341},{"id":"https://openalex.org/C99508421","wikidata":"https://www.wikidata.org/wiki/Q2678675","display_name":"Physical medicine and rehabilitation","level":1,"score":0.5838944911956787},{"id":"https://openalex.org/C2780640218","wikidata":"https://www.wikidata.org/wiki/Q8277","display_name":"Multiple sclerosis","level":2,"score":0.5781034827232361},{"id":"https://openalex.org/C173906292","wikidata":"https://www.wikidata.org/wiki/Q1493441","display_name":"Gait analysis","level":3,"score":0.4166823625564575},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.38740262389183044},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.34203243255615234},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000077107","descriptor_name":"Gait Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000077107","descriptor_name":"Gait Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000077107","descriptor_name":"Gait Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005684","descriptor_name":"Gait","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005684","descriptor_name":"Gait","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005684","descriptor_name":"Gait","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009103","descriptor_name":"Multiple Sclerosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009103","descriptor_name":"Multiple Sclerosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009103","descriptor_name":"Multiple Sclerosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016138","descriptor_name":"Walking","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016138","descriptor_name":"Walking","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016138","descriptor_name":"Walking","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020233","descriptor_name":"Gait Disorders, Neurologic","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D020233","descriptor_name":"Gait Disorders, Neurologic","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D020233","descriptor_name":"Gait Disorders, Neurologic","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D020233","descriptor_name":"Gait Disorders, Neurologic","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D020233","descriptor_name":"Gait Disorders, Neurologic","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D020233","descriptor_name":"Gait Disorders, Neurologic","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1109/tbme.2021.3061998","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tbme.2021.3061998","pdf_url":null,"source":{"id":"https://openalex.org/S5240358","display_name":"IEEE Transactions on Biomedical Engineering","issn_l":"0018-9294","issn":["0018-9294","1558-2531"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Biomedical Engineering","raw_type":"journal-article"},{"id":"pmid:33625975","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33625975","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE transactions on bio-medical engineering","raw_type":null},{"id":"pmh:oai:zenodo.org:5165205","is_oa":true,"landing_page_url":"https://zenodo.org/record/5165205","pdf_url":"https://zenodo.org/record/5165205","source":{"id":"https://openalex.org/S4306400562","display_name":"Zenodo (CERN European Organization for Nuclear Research)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I67311998","host_organization_name":"European Organization for Nuclear Research","host_organization_lineage":["https://openalex.org/I67311998"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"IEEE Transactions on Biomedical Engineering ( Early Access ) 1-1","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:eprints.whiterose.ac.uk:171615","is_oa":false,"landing_page_url":"https://eprints.whiterose.ac.uk/171615/","pdf_url":null,"source":{"id":"https://openalex.org/S4306400854","display_name":"White Rose Research Online (University of Leeds, The University of Sheffield, University of York)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I2800616092","host_organization_name":"White Rose University Consortium","host_organization_lineage":["https://openalex.org/I2800616092"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article"}],"best_oa_location":{"id":"pmh:oai:zenodo.org:5165205","is_oa":true,"landing_page_url":"https://zenodo.org/record/5165205","pdf_url":"https://zenodo.org/record/5165205","source":{"id":"https://openalex.org/S4306400562","display_name":"Zenodo (CERN European Organization for Nuclear Research)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I67311998","host_organization_name":"European Organization for Nuclear Research","host_organization_lineage":["https://openalex.org/I67311998"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"IEEE Transactions on Biomedical Engineering ( Early Access ) 1-1","raw_type":"info:eu-repo/semantics/article"},"sustainable_development_goals":[{"display_name":"Reduced inequalities","id":"https://metadata.un.org/sdg/10","score":0.6700000166893005}],"awards":[{"id":"https://openalex.org/G1083720994","display_name":"Modelling complex and partially identified engineering problems- Application to the individualised multiscale simulation of the musculoskeletal system","funder_award_id":"EP/K03877X/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G2959248599","display_name":"Connecting digital mobility assessment to clinical outcomes for regulatory and clinical endorsement","funder_award_id":"820820","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G3026994431","display_name":null,"funder_award_id":"EP/K03877X","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G4991818217","display_name":null,"funder_award_id":"EP/K03877X/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G531412971","display_name":null,"funder_award_id":"820820","funder_id":"https://openalex.org/F4320314178","funder_display_name":"European Federation of Pharmaceutical Industries and Associations"},{"id":"https://openalex.org/G5997855209","display_name":null,"funder_award_id":"EP/S032940/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G6206044308","display_name":null,"funder_award_id":"IS-BRC-1215","funder_id":"https://openalex.org/F4320319990","funder_display_name":"National Institute for Health and Care Research"},{"id":"https://openalex.org/G6404789827","display_name":null,"funder_award_id":"IS-BRC-1215-20017","funder_id":"https://openalex.org/F4320319990","funder_display_name":"National Institute for Health and Care Research"},{"id":"https://openalex.org/G7842005466","display_name":null,"funder_award_id":"Horizon 2020","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G8297189984","display_name":"Frontier Engineering: Progression Grant in Modelling complex and partially identified engineering problems. Application to the musculoskeletal system.","funder_award_id":"EP/S032940/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"}],"funders":[{"id":"https://openalex.org/F4320314178","display_name":"European Federation of Pharmaceutical Industries and Associations","ror":"https://ror.org/00g1x4v36"},{"id":"https://openalex.org/F4320319990","display_name":"National Institute for Health and Care Research","ror":"https://ror.org/0187kwz08"},{"id":"https://openalex.org/F4320319994","display_name":"Department of Health and Social Care","ror":"https://ror.org/03sbpja79"},{"id":"https://openalex.org/F4320320300","display_name":"European Commission","ror":"https://ror.org/00k4n6c32"},{"id":"https://openalex.org/F4320334627","display_name":"Engineering and Physical Sciences Research Council","ror":"https://ror.org/0439y7842"},{"id":"https://openalex.org/F4320336679","display_name":"NIHR Sheffield Clinical Research Facility","ror":null}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3129293921.pdf","grobid_xml":"https://content.openalex.org/works/W3129293921.grobid-xml"},"referenced_works_count":80,"referenced_works":["https://openalex.org/W2861960","https://openalex.org/W154757512","https://openalex.org/W1484864026","https://openalex.org/W1903118654","https://openalex.org/W1969422637","https://openalex.org/W1969781125","https://openalex.org/W1971834822","https://openalex.org/W1974078030","https://openalex.org/W1993760488","https://openalex.org/W1996474271","https://openalex.org/W2001818617","https://openalex.org/W2009643061","https://openalex.org/W2010201889","https://openalex.org/W2015309834","https://openalex.org/W2021470828","https://openalex.org/W2024321742","https://openalex.org/W2025403666","https://openalex.org/W2025897929","https://openalex.org/W2026051200","https://openalex.org/W2030210674","https://openalex.org/W2031974980","https://openalex.org/W2036589290","https://openalex.org/W2046168847","https://openalex.org/W2050294282","https://openalex.org/W2052257124","https://openalex.org/W2060997642","https://openalex.org/W2064363070","https://openalex.org/W2067086051","https://openalex.org/W2067581867","https://openalex.org/W2075837239","https://openalex.org/W2077059336","https://openalex.org/W2088477804","https://openalex.org/W2097919178","https://openalex.org/W2103955611","https://openalex.org/W2112165124","https://openalex.org/W2112374874","https://openalex.org/W2117531610","https://openalex.org/W2122376319","https://openalex.org/W2127374001","https://openalex.org/W2132524523","https://openalex.org/W2132677633","https://openalex.org/W2133097426","https://openalex.org/W2149115530","https://openalex.org/W2151529239","https://openalex.org/W2151657629","https://openalex.org/W2160172778","https://openalex.org/W2161163382","https://openalex.org/W2161634194","https://openalex.org/W2162908184","https://openalex.org/W2169766626","https://openalex.org/W2180900878","https://openalex.org/W2202556201","https://openalex.org/W2262326899","https://openalex.org/W2311828833","https://openalex.org/W2327749436","https://openalex.org/W2466956728","https://openalex.org/W2486278899","https://openalex.org/W2526655035","https://openalex.org/W2543182432","https://openalex.org/W2554960300","https://openalex.org/W2580134956","https://openalex.org/W2586302922","https://openalex.org/W2618747925","https://openalex.org/W2744736981","https://openalex.org/W2748897565","https://openalex.org/W2792355252","https://openalex.org/W2796038700","https://openalex.org/W2801415007","https://openalex.org/W2901140528","https://openalex.org/W2913204146","https://openalex.org/W2948165522","https://openalex.org/W2972224333","https://openalex.org/W2994708240","https://openalex.org/W2995012825","https://openalex.org/W3029517753","https://openalex.org/W3035332857","https://openalex.org/W4301808003","https://openalex.org/W6606322586","https://openalex.org/W6683921922","https://openalex.org/W6763954702"],"related_works":["https://openalex.org/W2133973503","https://openalex.org/W2471060339","https://openalex.org/W2111603423","https://openalex.org/W2148547327","https://openalex.org/W1989734657","https://openalex.org/W2125892956","https://openalex.org/W4226236273","https://openalex.org/W3116106933","https://openalex.org/W2790560349","https://openalex.org/W4226004263"],"abstract_inverted_index":{"OBJECTIVE:":[0],"Mobility":[1],"assessment":[2,220],"is":[3,42],"critical":[4],"in":[5,44,172,180,189,196,203,221,239,266],"the":[6,78,101,105,115,132,156,167,181,190,259],"clinical":[7],"management":[8],"of":[9,21,59,94,141,215],"people":[10],"with":[11,66,74,205,233,251],"Multiple":[12],"Sclerosis":[13],"(pwMS).":[14],"Instrumented":[15],"gait":[16,29,33,58,129,138,164,216,237],"analysis":[17,113,123],"provides":[18],"a":[19,32,54,89,120,206,263],"plethora":[20],"metrics":[22,98,234],"for":[23,85,108,217],"quantifying":[24],"concurrent":[25],"factors":[26],"contributing":[27,38],"to":[28,39,127,162],"deterioration.":[30],"However,":[31],"model":[34,139,214],"discriminating":[35],"underlying":[36],"features":[37,177,199],"this":[40],"deterioration":[41],"lacking":[43],"pwMS.":[45,267],"This":[46,112,257],"study":[47],"aimed":[48],"at":[49],"developing":[50],"and":[51,63,80,147,149,175,192,208,226],"validating":[52],"such":[53],"model.":[55],"METHODS:":[56],"The":[57,229],"24":[60],"healthy":[61],"controls":[62],"114":[64],"pwMS":[65,204,222],"mild,":[67],"moderate,":[68],"or":[69],"severe":[70,193,209],"disability":[71,134,168,247],"was":[72,153,160,200,223],"measured":[73],"inertial":[75],"sensors":[76],"on":[77],"shanks":[79],"lower":[81],"trunk":[82],"while":[83],"walking":[84,255],"6":[86],"minutes":[87],"along":[88],"hospital":[90],"corridor.":[91],"Twenty":[92],"out":[93],"thirty-six":[95],"initially":[96],"explored":[97],"computed":[99],"from":[100],"sensor":[102],"data":[103],"met":[104],"quality":[106],"criteria":[107],"exploratory":[109],"factor":[110,122,157],"analysis.":[111],"provided":[114],"sought":[116],"model,":[117,231],"which":[118,159],"underwent":[119],"confirmatory":[121],"before":[124],"being":[125],"used":[126],"characterize":[128],"impairment":[130,238],"across":[131,166,245],"three":[133],"groups.":[135,194],"RESULTS:":[136],"A":[137,212],"consisting":[140],"five":[142],"domains":[143],"(rhythm/variability,":[144],"pace,":[145],"asymmetry,":[146],"forward":[148],"lateral":[150],"dynamic":[151,197],"balance)":[152],"revealed":[154],"by":[155],"analysis,":[158],"able":[161],"highlight":[163],"abnormalities":[165],"groups:":[169],"significant":[170],"alterations":[171],"rhythm/variability-,":[173],"asymmetry-,":[174],"pace-based":[176],"were":[178,186],"present":[179],"mild":[182],"group,":[183],"but":[184],"these":[185],"more":[187],"profound":[188],"moderate":[191,207],"Deterioration":[195],"balance-based":[198],"only":[201],"noted":[202],"disability.":[210,256],"CONCLUSION:":[211],"conceptual":[213],"disease-specific":[218],"mobility":[219],"successfully":[224],"developed":[225],"tested.":[227],"SIGNIFICANCE:":[228],"new":[230],"built":[232],"that":[235],"represent":[236],"pwMS,":[240],"highlighted":[241],"clinically":[242,253],"relevant":[243],"changes":[244],"different":[246],"levels,":[248],"including":[249],"those":[250],"no":[252],"observable":[254],"shows":[258],"clear":[260],"potential":[261],"as":[262],"monitoring":[264],"biomarker":[265]},"counts_by_year":[{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":1}],"updated_date":"2026-05-05T08:41:31.759640","created_date":"2025-10-10T00:00:00"}
