{"id":"https://openalex.org/W3089181800","doi":"https://doi.org/10.1109/tbme.2020.3025992","title":"Detection of Leak From Left Atrial Appendage Occlusion Using Dielectric Imaging","display_name":"Detection of Leak From Left Atrial Appendage Occlusion Using Dielectric Imaging","publication_year":2020,"publication_date":"2020-09-22","ids":{"openalex":"https://openalex.org/W3089181800","doi":"https://doi.org/10.1109/tbme.2020.3025992","mag":"3089181800","pmid":"https://pubmed.ncbi.nlm.nih.gov/32960760"},"language":"en","primary_location":{"id":"doi:10.1109/tbme.2020.3025992","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tbme.2020.3025992","pdf_url":null,"source":{"id":"https://openalex.org/S5240358","display_name":"IEEE Transactions on Biomedical Engineering","issn_l":"0018-9294","issn":["0018-9294","1558-2531"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Biomedical Engineering","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5045871735","display_name":"Andy Adler","orcid":"https://orcid.org/0000-0002-2312-5346"},"institutions":[{"id":"https://openalex.org/I67031392","display_name":"Carleton University","ror":"https://ror.org/02qtvee93","country_code":"CA","type":"education","lineage":["https://openalex.org/I67031392"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Andy Adler","raw_affiliation_strings":["Systems and Computer engineering, Carleton University, Ottawa, ON, Canada"],"raw_orcid":"https://orcid.org/0000-0002-2312-5346","affiliations":[{"raw_affiliation_string":"Systems and Computer engineering, Carleton University, Ottawa, ON, Canada","institution_ids":["https://openalex.org/I67031392"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000534626","display_name":"Mazen Albaghdadi","orcid":"https://orcid.org/0000-0003-2369-0967"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mazen Albaghdadi","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110810000","display_name":"Usman Siddiqui","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Usman Siddiqui","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006150720","display_name":"Keren Bitton-Worms","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Keren Bitton-Worms","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088500809","display_name":"N. Racheli","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Noam Racheli","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079547186","display_name":"Urit Gordon","orcid":"https://orcid.org/0000-0002-0761-6970"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Urit Gordon","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-0761-6970","affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5013691399","display_name":"Karl\u2010Heinz K\u00fcck","orcid":"https://orcid.org/0000-0003-2649-3870"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Karl-Heinz Kuck","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.1949048,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"68","issue":"7","first_page":"2110","last_page":"2116"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10065","display_name":"Atrial Fibrillation Management and Outcomes","score":0.741599977016449,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10065","display_name":"Atrial Fibrillation Management and Outcomes","score":0.741599977016449,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10821","display_name":"Cardiovascular Function and Risk Factors","score":0.0357000008225441,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10598","display_name":"Cardiac pacing and defibrillation studies","score":0.03400000184774399,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/leak","display_name":"Leak","score":0.7705700397491455},{"id":"https://openalex.org/keywords/left-atrial-appendage-occlusion","display_name":"Left atrial appendage occlusion","score":0.7316180467605591},{"id":"https://openalex.org/keywords/occlusion","display_name":"Occlusion","score":0.5987439155578613},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.5066186189651489},{"id":"https://openalex.org/keywords/left-atrium","display_name":"Left atrium","score":0.4625742733478546},{"id":"https://openalex.org/keywords/thrombosis","display_name":"Thrombosis","score":0.4540896415710449},{"id":"https://openalex.org/keywords/nuclear-medicine","display_name":"Nuclear medicine","score":0.4191287159919739},{"id":"https://openalex.org/keywords/biomedical-engineering","display_name":"Biomedical engineering","score":0.400117427110672},{"id":"https://openalex.org/keywords/radiology","display_name":"Radiology","score":0.3457295298576355},{"id":"https://openalex.org/keywords/atrial-fibrillation","display_name":"Atrial fibrillation","score":0.2676907181739807},{"id":"https://openalex.org/keywords/cardiology","display_name":"Cardiology","score":0.2583464980125427},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.2472296953201294}],"concepts":[{"id":"https://openalex.org/C2780378346","wikidata":"https://www.wikidata.org/wiki/Q1349983","display_name":"Leak","level":2,"score":0.7705700397491455},{"id":"https://openalex.org/C2780434050","wikidata":"https://www.wikidata.org/wiki/Q6516934","display_name":"Left atrial appendage occlusion","level":4,"score":0.7316180467605591},{"id":"https://openalex.org/C2776268601","wikidata":"https://www.wikidata.org/wiki/Q968808","display_name":"Occlusion","level":2,"score":0.5987439155578613},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5066186189651489},{"id":"https://openalex.org/C2777615863","wikidata":"https://www.wikidata.org/wiki/Q1074839","display_name":"Left atrium","level":3,"score":0.4625742733478546},{"id":"https://openalex.org/C2780868729","wikidata":"https://www.wikidata.org/wiki/Q261327","display_name":"Thrombosis","level":2,"score":0.4540896415710449},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.4191287159919739},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.400117427110672},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.3457295298576355},{"id":"https://openalex.org/C2779161974","wikidata":"https://www.wikidata.org/wiki/Q815819","display_name":"Atrial fibrillation","level":2,"score":0.2676907181739807},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.2583464980125427},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2472296953201294},{"id":"https://openalex.org/C2776301958","wikidata":"https://www.wikidata.org/wiki/Q407431","display_name":"Warfarin","level":3,"score":0.0},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C87717796","wikidata":"https://www.wikidata.org/wiki/Q146326","display_name":"Environmental engineering","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001281","descriptor_name":"Atrial Fibrillation","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D001281","descriptor_name":"Atrial Fibrillation","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D001281","descriptor_name":"Atrial Fibrillation","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D004285","descriptor_name":"Dogs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004285","descriptor_name":"Dogs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004285","descriptor_name":"Dogs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006328","descriptor_name":"Cardiac Catheterization","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006328","descriptor_name":"Cardiac Catheterization","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006328","descriptor_name":"Cardiac Catheterization","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017548","descriptor_name":"Echocardiography, Transesophageal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017548","descriptor_name":"Echocardiography, Transesophageal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017548","descriptor_name":"Echocardiography, Transesophageal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020517","descriptor_name":"Atrial Appendage","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D020517","descriptor_name":"Atrial Appendage","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D020517","descriptor_name":"Atrial Appendage","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1109/tbme.2020.3025992","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tbme.2020.3025992","pdf_url":null,"source":{"id":"https://openalex.org/S5240358","display_name":"IEEE Transactions on Biomedical Engineering","issn_l":"0018-9294","issn":["0018-9294","1558-2531"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Biomedical Engineering","raw_type":"journal-article"},{"id":"pmid:32960760","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32960760","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE transactions on bio-medical engineering","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":17,"referenced_works":["https://openalex.org/W50472604","https://openalex.org/W2024246307","https://openalex.org/W2041556066","https://openalex.org/W2052625285","https://openalex.org/W2172022569","https://openalex.org/W2399533889","https://openalex.org/W2502670554","https://openalex.org/W2735337215","https://openalex.org/W2900607833","https://openalex.org/W2906245830","https://openalex.org/W2912139642","https://openalex.org/W2925736724","https://openalex.org/W2951528890","https://openalex.org/W3081909538","https://openalex.org/W4214932376","https://openalex.org/W6835001032","https://openalex.org/W6903673316"],"related_works":["https://openalex.org/W2338094139","https://openalex.org/W2789462655","https://openalex.org/W2884585138","https://openalex.org/W2792056316","https://openalex.org/W2002202225","https://openalex.org/W4220896216","https://openalex.org/W4366177555","https://openalex.org/W1980873795","https://openalex.org/W2570461067","https://openalex.org/W2763635242"],"abstract_inverted_index":{"BACKGROUND:":[0],"Peri-device":[1],"leak":[2,192,213],"(PDL)":[3],"following":[4],"left":[5,63,87],"atrial":[6,88],"appendage":[7,89],"occlusion":[8],"(LAAO)":[9],"may":[10],"lead":[11],"to":[12,40,45,171,196,226],"an":[13],"increased":[14],"risk":[15],"of":[16,37,150,186,202,230],"thrombosis.":[17],"However,":[18],"current":[19],"modalities":[20],"for":[21,228],"PDL":[22,47,187],"detection,":[23],"such":[24],"as":[25],"trans-esophageal":[26],"echo":[27],"(TEE)":[28],"and":[29,82,111,117,128,169,222,243],"cardiac":[30],"CT":[31],"do":[32],"not":[33],"provide":[34],"quantitative":[35],"measures":[36],"PDL.":[38,231],"OBJECTIVE:":[39],"use":[41],"dielectric":[42],"imaging":[43,238],"(DI)":[44],"measure":[46],"from":[48,85,215],"a":[49,79,93,200],"Watchman":[50],"(WM)":[51],"LAAO":[52,218],"device.":[53],"METHODS:":[54],"A":[55],"conductivity":[56,151],"contrast":[57,152,245],"agent":[58,246],"is":[59],"injected":[60,154],"into":[61,130],"the":[62,67,83,86,131,134,136,156,172,183,212,216],"atrium":[64],"(LA)":[65],"through":[66,155],"WM":[68,122,137,157,217],"delivery":[69,158],"system,":[70],"while":[71],"making":[72],"DI":[73,210,233],"measurements.":[74],"Recordings":[75],"are":[76],"analyzed":[77],"with":[78,199],"two-compartment":[80],"model":[81],"flow":[84,214],"(LAA)":[90],"characterized":[91],"by":[92],"\"%":[94],"clearance":[95],"/":[96],"beat\"":[97],"(CPB)":[98],"parameter.":[99],"With":[100],"ethics":[101],"approval,":[102],"four":[103],"dogs":[104],"(26":[105],"\u00b1":[106],"1.8":[107],"kg)":[108],"were":[109,115,126,167],"anesthetized":[110],"ventilated.":[112],"Body-surface":[113],"electrodes":[114],"placed":[116,129],"impedance":[118],"data":[119],"continuously":[120],"acquired.":[121],"devices":[123],"(0-35%":[124],"oversized)":[125],"introduced":[127],"LAA.":[132],"During":[133],"study,":[135],"was":[138,153],"either":[139],"fully":[140],"or":[141,240],"partial":[142],"deployed.":[143],"At":[144,160],"each":[145],"deployment":[146,162],"level,":[147],"10":[148],"mL":[149],"sheath.":[159],"twenty-two":[161],"conditions,":[163],"Doppler-flow":[164],"TEE":[165,191,227],"measurements":[166],"made,":[168],"compared":[170],"DI-based":[173],"value.":[174],"RESULTS:":[175],"In":[176],"all":[177],"cases,":[178],"CPB":[179,197],"values":[180,198],"correctly":[181],"predicted":[182],"TEE-based":[184],"assessment":[185],"(100%":[188],"sensitivity/specificity).":[189],"The":[190,232],"size":[193],"also":[194],"corresponded":[195],"correlation":[201],"r":[203],"=":[204],"0.914":[205],"(p":[206],"0.001).":[207],"CONCLUSION:":[208],"Using":[209],"signals,":[211],"can":[219],"be":[220],"measured":[221],"yields":[223],"comparative":[224],"results":[225],"detection":[229],"method":[234],"requires":[235],"no":[236],"other":[237],"modality":[239],"ionizing":[241],"radiation":[242],"iodine":[244],"injection.":[247]},"counts_by_year":[],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}