{"id":"https://openalex.org/W2758440563","doi":"https://doi.org/10.1109/tbme.2017.2756995","title":"An MRI-Compatible Hydrodynamic Simulator of Cerebrospinal Fluid Motion in the Cervical Spine","display_name":"An MRI-Compatible Hydrodynamic Simulator of Cerebrospinal Fluid Motion in the Cervical Spine","publication_year":2017,"publication_date":"2017-09-26","ids":{"openalex":"https://openalex.org/W2758440563","doi":"https://doi.org/10.1109/tbme.2017.2756995","mag":"2758440563","pmid":"https://pubmed.ncbi.nlm.nih.gov/28961100"},"language":"en","primary_location":{"id":"doi:10.1109/tbme.2017.2756995","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tbme.2017.2756995","pdf_url":null,"source":{"id":"https://openalex.org/S5240358","display_name":"IEEE Transactions on Biomedical Engineering","issn_l":"0018-9294","issn":["0018-9294","1558-2531"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Biomedical Engineering","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6025821","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5064226405","display_name":"Suraj Thyagaraj","orcid":"https://orcid.org/0000-0001-9150-1967"},"institutions":[{"id":"https://openalex.org/I110152177","display_name":"University of Akron","ror":"https://ror.org/02kyckx55","country_code":"US","type":"education","lineage":["https://openalex.org/I110152177"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Suraj Thyagaraj","raw_affiliation_strings":["University of Akron"],"raw_orcid":"https://orcid.org/0000-0001-9150-1967","affiliations":[{"raw_affiliation_string":"University of Akron","institution_ids":["https://openalex.org/I110152177"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045406087","display_name":"Soroush Heidari Pahlavian","orcid":"https://orcid.org/0000-0003-3729-851X"},"institutions":[{"id":"https://openalex.org/I110152177","display_name":"University of Akron","ror":"https://ror.org/02kyckx55","country_code":"US","type":"education","lineage":["https://openalex.org/I110152177"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Soroush Heidari Pahlavian","raw_affiliation_strings":["University of Akron"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Akron","institution_ids":["https://openalex.org/I110152177"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032110274","display_name":"Lucas R. Sass","orcid":null},"institutions":[{"id":"https://openalex.org/I155093810","display_name":"University of Idaho","ror":"https://ror.org/03hbp5t65","country_code":"US","type":"education","lineage":["https://openalex.org/I155093810"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lucas R. Sass","raw_affiliation_strings":["Department of Biological Engineering, University of Idaho"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological Engineering, University of Idaho","institution_ids":["https://openalex.org/I155093810"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037462628","display_name":"Francis Loth","orcid":"https://orcid.org/0000-0001-7651-521X"},"institutions":[{"id":"https://openalex.org/I110152177","display_name":"University of Akron","ror":"https://ror.org/02kyckx55","country_code":"US","type":"education","lineage":["https://openalex.org/I110152177"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Francis Loth","raw_affiliation_strings":["University of Akron"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Akron","institution_ids":["https://openalex.org/I110152177"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010499166","display_name":"Morteza Vatani","orcid":null},"institutions":[{"id":"https://openalex.org/I110152177","display_name":"University of Akron","ror":"https://ror.org/02kyckx55","country_code":"US","type":"education","lineage":["https://openalex.org/I110152177"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Morteza Vatani","raw_affiliation_strings":["University of Akron"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Akron","institution_ids":["https://openalex.org/I110152177"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101574201","display_name":"Jae\u2010Won Choi","orcid":"https://orcid.org/0000-0002-4253-126X"},"institutions":[{"id":"https://openalex.org/I110152177","display_name":"University of Akron","ror":"https://ror.org/02kyckx55","country_code":"US","type":"education","lineage":["https://openalex.org/I110152177"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jae-Won Choi","raw_affiliation_strings":["University of Akron"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Akron","institution_ids":["https://openalex.org/I110152177"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053911734","display_name":"R. Shane Tubbs","orcid":"https://orcid.org/0000-0003-1317-1047"},"institutions":[{"id":"https://openalex.org/I4210132770","display_name":"ISI Foundation","ror":"https://ror.org/03ebhsy64","country_code":"US","type":"other","lineage":["https://openalex.org/I4210132770"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"R. Shane Tubbs","raw_affiliation_strings":["Seattle Science Foundation"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Seattle Science Foundation","institution_ids":["https://openalex.org/I4210132770"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005791671","display_name":"Daniel Giese","orcid":"https://orcid.org/0000-0002-3925-4441"},"institutions":[{"id":"https://openalex.org/I4210153755","display_name":"University Hospital Cologne","ror":"https://ror.org/05mxhda18","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210153755"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Daniel Giese","raw_affiliation_strings":["University Hospital, Cologne, Germany"],"raw_orcid":"https://orcid.org/0000-0002-3925-4441","affiliations":[{"raw_affiliation_string":"University Hospital, Cologne, Germany","institution_ids":["https://openalex.org/I4210153755"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090323934","display_name":"Jan Robert Kr\u00f6ger","orcid":"https://orcid.org/0000-0003-1218-7610"},"institutions":[{"id":"https://openalex.org/I4210153755","display_name":"University Hospital Cologne","ror":"https://ror.org/05mxhda18","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210153755"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Jan-Robert Kroger","raw_affiliation_strings":["University Hospital, Cologne, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University Hospital, Cologne, Germany","institution_ids":["https://openalex.org/I4210153755"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018064840","display_name":"Alexander C. Bunck","orcid":"https://orcid.org/0000-0003-0986-0042"},"institutions":[{"id":"https://openalex.org/I4210153755","display_name":"University Hospital Cologne","ror":"https://ror.org/05mxhda18","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210153755"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Alexander C. Bunck","raw_affiliation_strings":["University Hospital, Cologne, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University Hospital, Cologne, Germany","institution_ids":["https://openalex.org/I4210153755"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5026496282","display_name":"Bryn A. Martin","orcid":"https://orcid.org/0000-0003-1234-7880"},"institutions":[{"id":"https://openalex.org/I155093810","display_name":"University of Idaho","ror":"https://ror.org/03hbp5t65","country_code":"US","type":"education","lineage":["https://openalex.org/I155093810"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Bryn A. Martin","raw_affiliation_strings":["Department of Biological Engineering, University of Idaho, Moscow, ID, USA"],"raw_orcid":"https://orcid.org/0000-0003-1234-7880","affiliations":[{"raw_affiliation_string":"Department of Biological Engineering, University of Idaho, Moscow, ID, USA","institution_ids":["https://openalex.org/I155093810"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":11,"corresponding_author_ids":["https://openalex.org/A5064226405"],"corresponding_institution_ids":["https://openalex.org/I110152177"],"apc_list":null,"apc_paid":null,"fwci":0.716,"has_fulltext":false,"cited_by_count":14,"citation_normalized_percentile":{"value":0.65027796,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":97},"biblio":{"volume":"65","issue":"7","first_page":"1516","last_page":"1523"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11406","display_name":"Cerebrospinal fluid and hydrocephalus","score":0.7296000123023987,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11406","display_name":"Cerebrospinal fluid and hydrocephalus","score":0.7296000123023987,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11669","display_name":"Head and Neck Surgical Oncology","score":0.09669999778270721,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11833","display_name":"Spinal Dysraphism and Malformations","score":0.027300000190734863,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cerebrospinal-fluid","display_name":"Cerebrospinal fluid","score":0.6361396908760071},{"id":"https://openalex.org/keywords/biomedical-engineering","display_name":"Biomedical engineering","score":0.5502023696899414},{"id":"https://openalex.org/keywords/magnetic-resonance-imaging","display_name":"Magnetic resonance imaging","score":0.47952914237976074},{"id":"https://openalex.org/keywords/dynamic-contrast-enhanced-mri","display_name":"Dynamic contrast-enhanced MRI","score":0.43147867918014526},{"id":"https://openalex.org/keywords/chiari-malformation","display_name":"Chiari malformation","score":0.41776737570762634},{"id":"https://openalex.org/keywords/nuclear-medicine","display_name":"Nuclear medicine","score":0.3317108154296875},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.32686102390289307},{"id":"https://openalex.org/keywords/radiology","display_name":"Radiology","score":0.2930116057395935},{"id":"https://openalex.org/keywords/pathology","display_name":"Pathology","score":0.15510481595993042},{"id":"https://openalex.org/keywords/syringomyelia","display_name":"Syringomyelia","score":0.08387815952301025}],"concepts":[{"id":"https://openalex.org/C2779651940","wikidata":"https://www.wikidata.org/wiki/Q54196","display_name":"Cerebrospinal fluid","level":2,"score":0.6361396908760071},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.5502023696899414},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.47952914237976074},{"id":"https://openalex.org/C41727105","wikidata":"https://www.wikidata.org/wiki/Q17009718","display_name":"Dynamic contrast-enhanced MRI","level":3,"score":0.43147867918014526},{"id":"https://openalex.org/C2781149351","wikidata":"https://www.wikidata.org/wiki/Q1071707","display_name":"Chiari malformation","level":4,"score":0.41776737570762634},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.3317108154296875},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.32686102390289307},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.2930116057395935},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.15510481595993042},{"id":"https://openalex.org/C2777836068","wikidata":"https://www.wikidata.org/wiki/Q1112977","display_name":"Syringomyelia","level":3,"score":0.08387815952301025}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002555","descriptor_name":"Cerebrospinal Fluid","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D002555","descriptor_name":"Cerebrospinal Fluid","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D002555","descriptor_name":"Cerebrospinal Fluid","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D002555","descriptor_name":"Cerebrospinal Fluid","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D002555","descriptor_name":"Cerebrospinal Fluid","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D002555","descriptor_name":"Cerebrospinal Fluid","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D002574","descriptor_name":"Cervical Vertebrae","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D002574","descriptor_name":"Cervical Vertebrae","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D002574","descriptor_name":"Cervical Vertebrae","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D002574","descriptor_name":"Cervical Vertebrae","qualifier_ui":"Q000033","qualifier_name":"anatomy & histology","is_major_topic":true},{"descriptor_ui":"D002574","descriptor_name":"Cervical Vertebrae","qualifier_ui":"Q000033","qualifier_name":"anatomy & histology","is_major_topic":true},{"descriptor_ui":"D002574","descriptor_name":"Cervical Vertebrae","qualifier_ui":"Q000033","qualifier_name":"anatomy & histology","is_major_topic":true},{"descriptor_ui":"D002574","descriptor_name":"Cervical Vertebrae","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D002574","descriptor_name":"Cervical Vertebrae","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D002574","descriptor_name":"Cervical Vertebrae","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D002675","descriptor_name":"Child, Preschool","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002675","descriptor_name":"Child, Preschool","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002675","descriptor_name":"Child, Preschool","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011673","descriptor_name":"Pulsatile Flow","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D011673","descriptor_name":"Pulsatile Flow","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D011673","descriptor_name":"Pulsatile Flow","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D013116","descriptor_name":"Spinal Cord","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D013116","descriptor_name":"Spinal Cord","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D013116","descriptor_name":"Spinal Cord","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D013116","descriptor_name":"Spinal Cord","qualifier_ui":"Q000033","qualifier_name":"anatomy & histology","is_major_topic":true},{"descriptor_ui":"D013116","descriptor_name":"Spinal Cord","qualifier_ui":"Q000033","qualifier_name":"anatomy & histology","is_major_topic":true},{"descriptor_ui":"D013116","descriptor_name":"Spinal Cord","qualifier_ui":"Q000033","qualifier_name":"anatomy & histology","is_major_topic":true},{"descriptor_ui":"D013116","descriptor_name":"Spinal Cord","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D013116","descriptor_name":"Spinal Cord","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D013116","descriptor_name":"Spinal Cord","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D066330","descriptor_name":"Printing, Three-Dimensional","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D066330","descriptor_name":"Printing, Three-Dimensional","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D066330","descriptor_name":"Printing, Three-Dimensional","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1109/tbme.2017.2756995","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tbme.2017.2756995","pdf_url":null,"source":{"id":"https://openalex.org/S5240358","display_name":"IEEE Transactions on Biomedical Engineering","issn_l":"0018-9294","issn":["0018-9294","1558-2531"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Biomedical Engineering","raw_type":"journal-article"},{"id":"pmid:28961100","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28961100","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE transactions on bio-medical engineering","raw_type":null},{"id":"pmh:oai:USBKOELN.ub.uni-koeln.de:18211","is_oa":false,"landing_page_url":null,"pdf_url":null,"source":{"id":"https://openalex.org/S4306400371","display_name":"K\u00f6lner Universit\u00e4ts PublikationsServer (Universit\u00e4t zu K\u00f6ln)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4210115942","host_organization_name":"Rhenish Institute for Environmental Research","host_organization_lineage":["https://openalex.org/I4210115942"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"doc-type:article"},{"id":"pmh:oai:pubmedcentral.nih.gov:6025821","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6025821","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"IEEE Trans Biomed Eng","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:6025821","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6025821","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"IEEE Trans Biomed Eng","raw_type":"Text"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G7697541026","display_name":null,"funder_award_id":"1R44MH112210-01A1","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"}],"funders":[{"id":"https://openalex.org/F4320309097","display_name":"Chiari and Syringomyelia Patient Education Foundation","ror":"https://ror.org/03ztzyx54"},{"id":"https://openalex.org/F4320320924","display_name":"Schweizerischer Nationalfonds zur F\u00f6rderung der Wissenschaftlichen Forschung","ror":"https://ror.org/00yjd3n13"},{"id":"https://openalex.org/F4320337346","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":57,"referenced_works":["https://openalex.org/W63071997","https://openalex.org/W583467739","https://openalex.org/W1078883356","https://openalex.org/W1267976076","https://openalex.org/W1825776128","https://openalex.org/W1864139176","https://openalex.org/W1951608601","https://openalex.org/W1972951903","https://openalex.org/W1973294015","https://openalex.org/W1983856219","https://openalex.org/W1988280787","https://openalex.org/W1991015725","https://openalex.org/W1993583045","https://openalex.org/W1994749920","https://openalex.org/W2005860242","https://openalex.org/W2015436559","https://openalex.org/W2018991205","https://openalex.org/W2029070417","https://openalex.org/W2029150110","https://openalex.org/W2030400138","https://openalex.org/W2047808495","https://openalex.org/W2048473291","https://openalex.org/W2051583167","https://openalex.org/W2057878992","https://openalex.org/W2061717576","https://openalex.org/W2071517607","https://openalex.org/W2087203227","https://openalex.org/W2087338943","https://openalex.org/W2089323979","https://openalex.org/W2097546287","https://openalex.org/W2113886121","https://openalex.org/W2121070898","https://openalex.org/W2122263253","https://openalex.org/W2124564923","https://openalex.org/W2127890285","https://openalex.org/W2132597772","https://openalex.org/W2133863856","https://openalex.org/W2140201210","https://openalex.org/W2140807934","https://openalex.org/W2153515407","https://openalex.org/W2157852355","https://openalex.org/W2161372017","https://openalex.org/W2265362213","https://openalex.org/W2467036931","https://openalex.org/W2562149908","https://openalex.org/W2579093854","https://openalex.org/W2584346819","https://openalex.org/W2592552360","https://openalex.org/W2612401068","https://openalex.org/W4242874715","https://openalex.org/W6640982571","https://openalex.org/W6647332744","https://openalex.org/W6648615703","https://openalex.org/W6649008838","https://openalex.org/W6693201454","https://openalex.org/W6719433871","https://openalex.org/W6732300386"],"related_works":["https://openalex.org/W2060257772","https://openalex.org/W2058773221","https://openalex.org/W2003001535","https://openalex.org/W2081363855","https://openalex.org/W1972670736","https://openalex.org/W2075327691","https://openalex.org/W2020948693","https://openalex.org/W2058167638","https://openalex.org/W2504770874","https://openalex.org/W2057983061"],"abstract_inverted_index":{"GOAL:":[0],"Develop":[1],"and":[2,32,62,113,125,145,213,245],"test":[3,235],"an":[4],"MRI-compatible":[5,168],"hydrodynamic":[6,169],"simulator":[7,170],"of":[8,51,55,94,171,238],"cerebrospinal":[9],"fluid":[10],"(CSF)":[11],"motion":[12,173],"in":[13,43,98,154,159,174,202,223,228],"the":[14,56,92,95,155,166,175,236],"cervical":[15,57,176],"spinal":[16,64],"subarachnoid":[17],"space.":[18],"Four":[19],"anatomically":[20,179],"realistic":[21,60,180],"subject-specific":[22],"models":[23,45,230],"were":[24,46,69,72,128,183],"created":[25],"based":[26,47],"on":[27,48],"a":[28,33,191],"22-year-old":[29],"healthy":[30],"volunteer":[31],"five-year-old":[34],"patient":[35],"diagnosed":[36],"with":[37,79,178],"Chiari":[38,207],"I":[39,208],"malformation.":[40,209],"METHODS:":[41],"The":[42,133,226],"vitro":[44,229],"manual":[49],"segmentation":[50],"high-resolution":[52],"T2-weighted":[53,112],"MRI":[54,117,210,242],"spine.":[58],"Anatomically":[59],"dorsal":[61],"ventral":[63],"cord":[65],"nerve":[66],"rootlets":[67],"(NR)":[68],"added.":[70],"Models":[71],"three":[73],"dimensional":[74],"(3-D)":[75],"printed":[76],"by":[77,103,111,158],"stereolithography":[78],"50-\u03bcm":[80],"layer":[81],"thickness.":[82],"A":[83],"computer":[84],"controlled":[85],"pump":[86],"system":[87],"was":[88,108],"used":[89,217,233],"to":[90,150,185,190,199,218,234],"replicate":[91],"shape":[93],"subject":[96],"specific":[97],"vivo":[99,160],"CSF":[100,135,172,187,195,220],"flow":[101,221],"measured":[102,157],"phase-contrast":[104],"MRI.":[105,161],"Each":[106],"model":[107],"then":[109],"scanned":[110],"4-D":[114],"phase":[115],"contrast":[116],"(4D":[118],"flow).":[119],"RESULTS:":[120],"Cross-sectional":[121],"area,":[122],"wetted":[123],"perimeter,":[124],"hydraulic":[126],"diameter":[127],"quantified":[129],"for":[130],"each":[131],"model.":[132],"oscillatory":[134],"velocity":[136,142,188],"field":[137],"(flow":[138],"jets":[139],"near":[140],"NR,":[141],"profile":[143],"shape,":[144],"magnitude)":[146],"had":[147],"similar":[148],"characteristics":[149],"previously":[151],"reported":[152],"studies":[153],"literature":[156],"CONCLUSION:":[162],"This":[163],"study":[164],"describes":[165],"first":[167],"spine":[177],"NR.":[181],"NR":[182],"found":[184],"impact":[186],"profiles":[189],"great":[192],"degree.":[193],"SIGNIFICANCE:":[194],"hydrodynamics":[196],"are":[197],"thought":[198],"be":[200,216,232],"altered":[201],"craniospinal":[203],"disorders":[204],"such":[205],"as":[206],"scanning":[211],"techniques":[212],"protocols":[214,240],"can":[215,231],"quantify":[219],"alterations":[222],"disease":[224],"states.":[225],"provided":[227],"reliability":[237],"these":[239],"across":[241],"scanner":[243],"manufacturers":[244],"machines.":[246]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1}],"updated_date":"2026-04-29T09:16:38.111599","created_date":"2025-10-10T00:00:00"}