{"id":"https://openalex.org/W2536228793","doi":"https://doi.org/10.1109/tbme.2016.2619489","title":"Prediction of Atherosclerotic Plaque Development in an In Vivo Coronary Arterial Segment Based on a Multilevel Modeling Approach","display_name":"Prediction of Atherosclerotic Plaque Development in an In Vivo Coronary Arterial Segment Based on a Multilevel Modeling Approach","publication_year":2016,"publication_date":"2016-10-19","ids":{"openalex":"https://openalex.org/W2536228793","doi":"https://doi.org/10.1109/tbme.2016.2619489","mag":"2536228793","pmid":"https://pubmed.ncbi.nlm.nih.gov/28113248"},"language":"en","primary_location":{"id":"doi:10.1109/tbme.2016.2619489","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tbme.2016.2619489","pdf_url":null,"source":{"id":"https://openalex.org/S5240358","display_name":"IEEE Transactions on Biomedical Engineering","issn_l":"0018-9294","issn":["0018-9294","1558-2531"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Biomedical Engineering","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5079931924","display_name":"Antonis I. Sakellarios","orcid":"https://orcid.org/0000-0002-2272-9543"},"institutions":[{"id":"https://openalex.org/I194019607","display_name":"University of Ioannina","ror":"https://ror.org/01qg3j183","country_code":"GR","type":"education","lineage":["https://openalex.org/I194019607"]}],"countries":["GR"],"is_corresponding":true,"raw_author_name":"Antonis I. Sakellarios","raw_affiliation_strings":["Unit of Medical Technology and Intelligent Information Systems, Department of Materials Science and Engineering and Department of Biomedical Research, University of Ioannina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Unit of Medical Technology and Intelligent Information Systems, Department of Materials Science and Engineering and Department of Biomedical Research, University of Ioannina","institution_ids":["https://openalex.org/I194019607"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110405593","display_name":"Lorenz R\u00e4ber","orcid":null},"institutions":[{"id":"https://openalex.org/I2801112126","display_name":"University Hospital of Bern","ror":"https://ror.org/01q9sj412","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I2801112126"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Lorenz Raber","raw_affiliation_strings":["Department of Interventional Cardiology, Bern University Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Interventional Cardiology, Bern University Hospital","institution_ids":["https://openalex.org/I2801112126"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050124666","display_name":"Christos V. Bourantas","orcid":"https://orcid.org/0000-0001-5319-1064"},"institutions":[{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Christos V. Bourantas","raw_affiliation_strings":["Department of Cardiovascular Sciences, University College London"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiovascular Sciences, University College London","institution_ids":["https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051663494","display_name":"Themis P. Exarchos","orcid":"https://orcid.org/0000-0001-9420-9419"},"institutions":[{"id":"https://openalex.org/I194019607","display_name":"University of Ioannina","ror":"https://ror.org/01qg3j183","country_code":"GR","type":"education","lineage":["https://openalex.org/I194019607"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Themis P. Exarchos","raw_affiliation_strings":["Department of Biomedical Research, University of Ioannina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Research, University of Ioannina","institution_ids":["https://openalex.org/I194019607"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056992421","display_name":"Lambros S. Athanasiou","orcid":"https://orcid.org/0000-0002-8029-1332"},"institutions":[{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lambros S. Athanasiou","raw_affiliation_strings":["Institute of Medical Engineering and Science, Massachusetts Institute of Technology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Medical Engineering and Science, Massachusetts Institute of Technology","institution_ids":["https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067763637","display_name":"Gualtiero Pelosi","orcid":"https://orcid.org/0000-0001-7472-2186"},"institutions":[{"id":"https://openalex.org/I4210128591","display_name":"National Research Council","ror":"https://ror.org/035rrps97","country_code":"RO","type":"government","lineage":["https://openalex.org/I4210128591"]}],"countries":["RO"],"is_corresponding":false,"raw_author_name":"Gualtiero Pelosi","raw_affiliation_strings":["Institute of Clinical Physiology, National Research Council"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Clinical Physiology, National Research Council","institution_ids":["https://openalex.org/I4210128591"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103127491","display_name":"Konstantinos C. Koskinas","orcid":"https://orcid.org/0000-0002-5589-7762"},"institutions":[{"id":"https://openalex.org/I2801112126","display_name":"University Hospital of Bern","ror":"https://ror.org/01q9sj412","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I2801112126"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Konstantinos C. Koskinas","raw_affiliation_strings":["Department of Interventional Cardiology, Bern University Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Interventional Cardiology, Bern University Hospital","institution_ids":["https://openalex.org/I2801112126"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057116470","display_name":"Oberdan Parodi","orcid":"https://orcid.org/0000-0003-2459-1047"},"institutions":[{"id":"https://openalex.org/I4210128591","display_name":"National Research Council","ror":"https://ror.org/035rrps97","country_code":"RO","type":"government","lineage":["https://openalex.org/I4210128591"]}],"countries":["RO"],"is_corresponding":false,"raw_author_name":"Oberdan Parodi","raw_affiliation_strings":["Institute of Clinical Physiology, National Research Council"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Clinical Physiology, National Research Council","institution_ids":["https://openalex.org/I4210128591"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025715284","display_name":"Katerina \u039a. Naka","orcid":"https://orcid.org/0000-0002-9900-9659"},"institutions":[{"id":"https://openalex.org/I194019607","display_name":"University of Ioannina","ror":"https://ror.org/01qg3j183","country_code":"GR","type":"education","lineage":["https://openalex.org/I194019607"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Katerina K. Naka","raw_affiliation_strings":["Michaelideion Cardiac Center, University of Ioannina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Michaelideion Cardiac Center, University of Ioannina","institution_ids":["https://openalex.org/I194019607"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108123560","display_name":"Lampros K. Michalis","orcid":"https://orcid.org/0000-0001-8834-4462"},"institutions":[{"id":"https://openalex.org/I194019607","display_name":"University of Ioannina","ror":"https://ror.org/01qg3j183","country_code":"GR","type":"education","lineage":["https://openalex.org/I194019607"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Lampros K. Michalis","raw_affiliation_strings":["Michaelideion Cardiac Center, University of Ioannina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Michaelideion Cardiac Center, University of Ioannina","institution_ids":["https://openalex.org/I194019607"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063792624","display_name":"Patrick W. Serruys","orcid":"https://orcid.org/0000-0002-9636-1104"},"institutions":[{"id":"https://openalex.org/I2801952686","display_name":"Erasmus MC","ror":"https://ror.org/018906e22","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2801952686"]},{"id":"https://openalex.org/I913958620","display_name":"Erasmus University Rotterdam","ror":"https://ror.org/057w15z03","country_code":"NL","type":"education","lineage":["https://openalex.org/I913958620"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Patrick W. Serruys","raw_affiliation_strings":["Department of Interventional Cardiology, Thoraxcenter, Erasmus MC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Interventional Cardiology, Thoraxcenter, Erasmus MC","institution_ids":["https://openalex.org/I913958620","https://openalex.org/I2801952686"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081547954","display_name":"H\u00e9ctor M. Garc\u00eda\u2010Garc\u00eda","orcid":"https://orcid.org/0000-0001-5100-0471"},"institutions":[{"id":"https://openalex.org/I1285739803","display_name":"MedStar Washington Hospital Center","ror":"https://ror.org/05ry42w04","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285739803","https://openalex.org/I86755215"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hector M. Garcia-Garcia","raw_affiliation_strings":["Department of Interventional Cardiology, MedStar Washington Hospital Center"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Interventional Cardiology, MedStar Washington Hospital Center","institution_ids":["https://openalex.org/I1285739803"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053194091","display_name":"Stephan Windecker","orcid":"https://orcid.org/0000-0003-2653-6762"},"institutions":[{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Stephan Windecker","raw_affiliation_strings":["Department of Cardiovascular Sciences, University College London"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiovascular Sciences, University College London","institution_ids":["https://openalex.org/I45129253"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5037813012","display_name":"Dimitrios I. Fotiadis","orcid":"https://orcid.org/0000-0002-7362-5082"},"institutions":[{"id":"https://openalex.org/I194019607","display_name":"University of Ioannina","ror":"https://ror.org/01qg3j183","country_code":"GR","type":"education","lineage":["https://openalex.org/I194019607"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Dimitrios I. Fotiadis","raw_affiliation_strings":["Unit of Medical Technology and Intelligent Information Systems, Department of Materials Science and Engineering and the Department of Biomedical Research, University of Ioannina, Ioannina, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Unit of Medical Technology and Intelligent Information Systems, Department of Materials Science and Engineering and the Department of Biomedical Research, University of Ioannina, Ioannina, Greece","institution_ids":["https://openalex.org/I194019607"]}]}],"institutions":[],"countries_distinct_count":6,"institutions_distinct_count":14,"corresponding_author_ids":["https://openalex.org/A5079931924"],"corresponding_institution_ids":["https://openalex.org/I194019607"],"apc_list":null,"apc_paid":null,"fwci":5.948,"has_fulltext":false,"cited_by_count":39,"citation_normalized_percentile":{"value":0.96478282,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":91,"max":99},"biblio":{"volume":"64","issue":"8","first_page":"1721","last_page":"1730"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10193","display_name":"Coronary Interventions and Diagnostics","score":0.7027000188827515,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10193","display_name":"Coronary Interventions and Diagnostics","score":0.7027000188827515,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10924","display_name":"Cardiovascular Health and Disease Prevention","score":0.04560000076889992,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12955","display_name":"Atherosclerosis and Cardiovascular Diseases","score":0.04089999943971634,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/artery","display_name":"Artery","score":0.5107543468475342},{"id":"https://openalex.org/keywords/lipoprotein","display_name":"Lipoprotein","score":0.4668574631214142},{"id":"https://openalex.org/keywords/in-vivo","display_name":"In vivo","score":0.45008036494255066},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.3536199927330017},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.3509536385536194},{"id":"https://openalex.org/keywords/biomedical-engineering","display_name":"Biomedical engineering","score":0.3493480682373047},{"id":"https://openalex.org/keywords/cardiology","display_name":"Cardiology","score":0.331981897354126},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.2903137505054474},{"id":"https://openalex.org/keywords/cholesterol","display_name":"Cholesterol","score":0.2612293064594269},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.19368714094161987},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.1875801682472229}],"concepts":[{"id":"https://openalex.org/C2776820930","wikidata":"https://www.wikidata.org/wiki/Q9655","display_name":"Artery","level":2,"score":0.5107543468475342},{"id":"https://openalex.org/C2780072125","wikidata":"https://www.wikidata.org/wiki/Q28350","display_name":"Lipoprotein","level":3,"score":0.4668574631214142},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.45008036494255066},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.3536199927330017},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3509536385536194},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.3493480682373047},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.331981897354126},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2903137505054474},{"id":"https://openalex.org/C2778163477","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Cholesterol","level":2,"score":0.2612293064594269},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.19368714094161987},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.1875801682472229},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D001783","descriptor_name":"Blood Flow Velocity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001783","descriptor_name":"Blood Flow Velocity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001783","descriptor_name":"Blood Flow Velocity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001794","descriptor_name":"Blood Pressure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001794","descriptor_name":"Blood Pressure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001794","descriptor_name":"Blood Pressure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003324","descriptor_name":"Coronary Artery Disease","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D003324","descriptor_name":"Coronary Artery Disease","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D003324","descriptor_name":"Coronary Artery Disease","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D003331","descriptor_name":"Coronary Vessels","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D003331","descriptor_name":"Coronary Vessels","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D003331","descriptor_name":"Coronary Vessels","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D003936","descriptor_name":"Diagnosis, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D003936","descriptor_name":"Diagnosis, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D003936","descriptor_name":"Diagnosis, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D004730","descriptor_name":"Endothelium, Vascular","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D004730","descriptor_name":"Endothelium, Vascular","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D004730","descriptor_name":"Endothelium, Vascular","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008077","descriptor_name":"Lipoproteins, LDL","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D008077","descriptor_name":"Lipoproteins, LDL","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D008077","descriptor_name":"Lipoproteins, LDL","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D008955","descriptor_name":"Models, Cardiovascular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008955","descriptor_name":"Models, Cardiovascular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008955","descriptor_name":"Models, Cardiovascular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009000","descriptor_name":"Monocytes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009000","descriptor_name":"Monocytes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009000","descriptor_name":"Monocytes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D033081","descriptor_name":"Shear Strength","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D033081","descriptor_name":"Shear Strength","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D033081","descriptor_name":"Shear Strength","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D058226","descriptor_name":"Plaque, Atherosclerotic","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D058226","descriptor_name":"Plaque, Atherosclerotic","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D058226","descriptor_name":"Plaque, Atherosclerotic","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1109/tbme.2016.2619489","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tbme.2016.2619489","pdf_url":null,"source":{"id":"https://openalex.org/S5240358","display_name":"IEEE Transactions on Biomedical Engineering","issn_l":"0018-9294","issn":["0018-9294","1558-2531"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Biomedical Engineering","raw_type":"journal-article"},{"id":"pmid:28113248","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28113248","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE transactions on bio-medical engineering","raw_type":null},{"id":"pmh:oai:pure.eur.nl:openaire_cris_publications/1823632f-c118-4a43-a530-2bcdea305720","is_oa":false,"landing_page_url":"https://pure.eur.nl/en/publications/1823632f-c118-4a43-a530-2bcdea305720","pdf_url":null,"source":{"id":"https://openalex.org/S4306401266","display_name":"EUR Research Repository (Erasmus University Rotterdam)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I913958620","host_organization_name":"Erasmus University Rotterdam","host_organization_lineage":["https://openalex.org/I913958620"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sakellarios, A I, Raber, L, Bektas, F, Exarchos, T P, Athanasiou, L S, Pelosi, G, Koskinas, KC, Parodi, O, Naka, KK, Michalis, LK, Serruys, PWJC, Garcia Garcia, H, Windecker, S & Fotiadis, DI 2017, 'Prediction of Atherosclerotic Plaque Development in an In Vivo Coronary Arterial Segment Based on a Multilevel Modeling Approach', IEEE Transactions on Biomedical Engineering, vol. 64, no. 8, pp. 1721-1730. https://doi.org/10.1109/tbme.2016.2619489","raw_type":"info:eu-repo/semantics/publishedVersion"},{"id":"pmh:oai:boris.unibe.ch:89634","is_oa":false,"landing_page_url":"https://boris.unibe.ch/89634/","pdf_url":null,"source":{"id":"https://openalex.org/S4306401086","display_name":"Bern Open Repository and Information System (University of Bern)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I118564535","host_organization_name":"University of Bern","host_organization_lineage":["https://openalex.org/I118564535"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Sakellarios, Antonis; R\u00e4ber, Lorenz; Bourantas, Christos; Exarchos, Themis; Athanasiou, Lambros; Pelosi, Gualtiero; Parodi, Oberdan; Koskinas, Konstantinos; Naka, Katerina; Michalis, Lampros; Serruys, Patrick Wjc; Garcia-Garcia, Hector; Windecker, Stephan; Fotiadis, Dimitrios (2016). Prediction of Atherosclerotic Plaque Development in an in Vivo Coronary Arterial Segment Based on a Multi-level Modeling Approach. IEEE transactions on bio-medical engineering, 64(8), pp. 1721-1730. Institute of Electrical and Electronics Engineers 10.1109/TBME.2016.2619489 <http://dx.doi.org/10.1109/TBME.2016.2619489>","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:pure.eur.nl:publications/1823632f-c118-4a43-a530-2bcdea305720","is_oa":false,"landing_page_url":"http://hdl.handle.net/1765/108199","pdf_url":null,"source":{"id":"https://openalex.org/S4306401266","display_name":"EUR Research Repository (Erasmus University Rotterdam)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I913958620","host_organization_name":"Erasmus University Rotterdam","host_organization_lineage":["https://openalex.org/I913958620"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Sakellarios, A I, Raber, L, Bektas, F, Exarchos, T P, Athanasiou, L S, Pelosi, G, Koskinas, KC, Parodi, O, Naka, KK, Michalis, LK, Serruys, PWJC, Garcia Garcia, H, Windecker, S & Fotiadis, DI 2017, 'Prediction of Atherosclerotic Plaque Development in an In Vivo Coronary Arterial Segment Based on a Multilevel Modeling Approach', IEEE Transactions on Biomedical Engineering, vol. 64, no. 8, pp. 1721-1730. https://doi.org/10.1109/tbme.2016.2619489","raw_type":"info:eu-repo/semantics/publishedVersion"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.7900000214576721,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320320300","display_name":"European Commission","ror":"https://ror.org/00k4n6c32"},{"id":"https://openalex.org/F4320332999","display_name":"Horizon 2020 Framework Programme","ror":"https://ror.org/00k4n6c32"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":56,"referenced_works":["https://openalex.org/W66253097","https://openalex.org/W169756522","https://openalex.org/W1808354464","https://openalex.org/W1916728005","https://openalex.org/W1974936467","https://openalex.org/W1978997526","https://openalex.org/W1981386994","https://openalex.org/W1981439721","https://openalex.org/W1982748428","https://openalex.org/W1983246589","https://openalex.org/W1987321742","https://openalex.org/W1994764502","https://openalex.org/W1996520888","https://openalex.org/W1999772071","https://openalex.org/W2002241752","https://openalex.org/W2016234984","https://openalex.org/W2026856116","https://openalex.org/W2029736827","https://openalex.org/W2029932253","https://openalex.org/W2031239688","https://openalex.org/W2031672510","https://openalex.org/W2039416446","https://openalex.org/W2046242274","https://openalex.org/W2054865678","https://openalex.org/W2063338283","https://openalex.org/W2064200914","https://openalex.org/W2064408907","https://openalex.org/W2076815328","https://openalex.org/W2079594358","https://openalex.org/W2081406581","https://openalex.org/W2083157718","https://openalex.org/W2091399349","https://openalex.org/W2099167181","https://openalex.org/W2102725965","https://openalex.org/W2106377792","https://openalex.org/W2107618142","https://openalex.org/W2113463192","https://openalex.org/W2114646598","https://openalex.org/W2120439472","https://openalex.org/W2124488388","https://openalex.org/W2124888871","https://openalex.org/W2126915336","https://openalex.org/W2137445105","https://openalex.org/W2148110499","https://openalex.org/W2155748418","https://openalex.org/W2156920951","https://openalex.org/W2162405407","https://openalex.org/W2164807534","https://openalex.org/W2166251000","https://openalex.org/W2204016289","https://openalex.org/W2293286159","https://openalex.org/W2305437105","https://openalex.org/W2338864458","https://openalex.org/W6606872385","https://openalex.org/W6640094407","https://openalex.org/W6698164539"],"related_works":["https://openalex.org/W2259135539","https://openalex.org/W2386767533","https://openalex.org/W2384249492","https://openalex.org/W2530489557","https://openalex.org/W2361643785","https://openalex.org/W2899373552","https://openalex.org/W2784329749","https://openalex.org/W2143770519","https://openalex.org/W1755950832","https://openalex.org/W2155649652"],"abstract_inverted_index":{"OBJECTIVE:":[0],"The":[1,56,79],"aim":[2],"of":[3,11,44,47,62,83,86,173,176],"this":[4,22,180],"study":[5],"is":[6,31,171],"to":[7,76,101,114,156,160,166,185,188],"explore":[8],"major":[9,104],"mechanisms":[10,105],"atherosclerotic":[12],"plaque":[13,141,167],"growth,":[14],"presenting":[15],"a":[16,24,34,121],"proof-of-concept":[17],"numerical":[18],"model.":[19],"METHODS:":[20],"To":[21],"aim,":[23],"human":[25],"reconstructed":[26],"left":[27],"circumflex":[28],"coronary":[29],"artery":[30],"utilized":[32],"for":[33],"multilevel":[35],"modeling":[36,46,61,85,96],"approach.":[37],"More":[38],"specifically,":[39],"the":[40,45,60,73,84,103,109,116,127,132,158],"first":[41],"level":[42,58,81],"consists":[43],"blood":[48],"flow":[49],"and":[50,66,69,91,140],"endothelial":[51,74],"shear":[52],"stress":[53],"(ESS)":[54],"computation.":[55],"second":[57],"includes":[59],"low-density":[63],"lipoprotein":[64,68],"(LDL)":[65],"high-density":[67],"monocytes":[70],"transport":[71],"through":[72],"membrane":[75],"vessel":[77],"wall.":[78],"third":[80],"comprises":[82],"LDL":[87],"oxidation,":[88],"macrophages":[89],"differentiation,":[90],"foam":[92],"cells":[93],"formation.":[94],"All":[95],"levels":[97],"integrate":[98],"experimental":[99],"findings":[100],"describe":[102],"that":[106],"occur":[107],"in":[108,134],"arterial":[110,135],"physiology.":[111],"In":[112],"order":[113],"validate":[115],"proposed":[117],"approach,":[118],"we":[119],"utilize":[120],"patient":[122],"specific":[123],"scenario":[124],"by":[125],"comparing":[126],"baseline":[128],"computational":[129,151,182],"results":[130],"with":[131],"changes":[133],"wall":[136],"thickness,":[137],"lumen":[138],"diameter,":[139],"components":[142],"using":[143],"follow-up":[144],"data.":[145],"RESULTS:":[146],"=":[147],"0.738)].":[148],"CONCLUSION:":[149],"Advanced":[150],"models":[152,183],"can":[153],"be":[154,186],"used":[155],"increase":[157],"accuracy":[159],"predict":[161,189],"regions":[162],"which":[163],"are":[164],"prone":[165],"development.":[168],"SIGNIFICANCE:":[169],"Atherosclerosis":[170],"one":[172],"leading":[174],"causes":[175],"death":[177],"worldwide.":[178],"For":[179],"purpose":[181],"have":[184],"implemented":[187],"disease":[190],"progression.":[191]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":7},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":7},{"year":2017,"cited_by_count":9}],"updated_date":"2026-04-29T09:16:38.111599","created_date":"2025-10-10T00:00:00"}