{"id":"https://openalex.org/W2471596589","doi":"https://doi.org/10.1109/tbme.2016.2582734","title":"Development and Phantom Validation of a 3-D-Ultrasound-Guided System for Targeting MRI-Visible Lesions During Transrectal Prostate Biopsy","display_name":"Development and Phantom Validation of a 3-D-Ultrasound-Guided System for Targeting MRI-Visible Lesions During Transrectal Prostate Biopsy","publication_year":2016,"publication_date":"2016-06-23","ids":{"openalex":"https://openalex.org/W2471596589","doi":"https://doi.org/10.1109/tbme.2016.2582734","mag":"2471596589","pmid":"https://pubmed.ncbi.nlm.nih.gov/27337710"},"language":"en","primary_location":{"id":"doi:10.1109/tbme.2016.2582734","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tbme.2016.2582734","pdf_url":null,"source":{"id":"https://openalex.org/S5240358","display_name":"IEEE Transactions on Biomedical Engineering","issn_l":"0018-9294","issn":["0018-9294","1558-2531"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Biomedical Engineering","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5053368","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5032309114","display_name":"Yipeng Hu","orcid":"https://orcid.org/0000-0003-4902-0486"},"institutions":[{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Yipeng Hu","raw_affiliation_strings":["UCL Centre for Medical Image Computing, Department of Medical Physics and Biomedical Engineering, University College London, London, U.K"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UCL Centre for Medical Image Computing, Department of Medical Physics and Biomedical Engineering, University College London, London, U.K","institution_ids":["https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046040598","display_name":"Veeru Kasivisvanathan","orcid":"https://orcid.org/0000-0002-0832-382X"},"institutions":[{"id":"https://openalex.org/I4210122016","display_name":"Wellcome / EPSRC Centre for Interventional and Surgical Sciences","ror":"https://ror.org/03r42r570","country_code":"GB","type":"facility","lineage":["https://openalex.org/I124357947","https://openalex.org/I1299528221","https://openalex.org/I4210087105","https://openalex.org/I4210122016","https://openalex.org/I45129253","https://openalex.org/I87048295"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Veeru Kasivisvanathan","raw_affiliation_strings":["Division of Surgical and Interventional SciencesUniversity College London","Division of Surgical and Interventional Sciences, University College London"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Surgical and Interventional SciencesUniversity College London","institution_ids":["https://openalex.org/I4210122016","https://openalex.org/I45129253"]},{"raw_affiliation_string":"Division of Surgical and Interventional Sciences, University College London","institution_ids":["https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033177902","display_name":"Lucy Simmons","orcid":"https://orcid.org/0000-0002-2112-6038"},"institutions":[{"id":"https://openalex.org/I4210122016","display_name":"Wellcome / EPSRC Centre for Interventional and Surgical Sciences","ror":"https://ror.org/03r42r570","country_code":"GB","type":"facility","lineage":["https://openalex.org/I124357947","https://openalex.org/I1299528221","https://openalex.org/I4210087105","https://openalex.org/I4210122016","https://openalex.org/I45129253","https://openalex.org/I87048295"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Lucy A. M. Simmons","raw_affiliation_strings":["Division of Surgical and Interventional SciencesUniversity College London","Division of Surgical and Interventional Sciences, University College London"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Surgical and Interventional SciencesUniversity College London","institution_ids":["https://openalex.org/I4210122016","https://openalex.org/I45129253"]},{"raw_affiliation_string":"Division of Surgical and Interventional Sciences, University College London","institution_ids":["https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001311980","display_name":"Matthew J. Clarkson","orcid":"https://orcid.org/0000-0002-5565-1252"},"institutions":[{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Matthew J. Clarkson","raw_affiliation_strings":["UCL Centre for Medical Image Computing, Department of Medical Physics and Biomedical EngineeringUniversity College London","UCL Centre for Medical Image Computing, Department of Medical Physics and Biomedical Engineering, University College London"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UCL Centre for Medical Image Computing, Department of Medical Physics and Biomedical EngineeringUniversity College London","institution_ids":["https://openalex.org/I45129253"]},{"raw_affiliation_string":"UCL Centre for Medical Image Computing, Department of Medical Physics and Biomedical Engineering, University College London","institution_ids":["https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009863636","display_name":"Stephen Thompson","orcid":"https://orcid.org/0000-0001-7286-1326"},"institutions":[{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Stephen A. Thompson","raw_affiliation_strings":["UCL Centre for Medical Image Computing, Department of Medical Physics and Biomedical EngineeringUniversity College London","UCL Centre for Medical Image Computing, Department of Medical Physics and Biomedical Engineering, University College London"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UCL Centre for Medical Image Computing, Department of Medical Physics and Biomedical EngineeringUniversity College London","institution_ids":["https://openalex.org/I45129253"]},{"raw_affiliation_string":"UCL Centre for Medical Image Computing, Department of Medical Physics and Biomedical Engineering, University College London","institution_ids":["https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021876584","display_name":"Taimur T. Shah","orcid":"https://orcid.org/0000-0003-1642-1208"},"institutions":[{"id":"https://openalex.org/I4210122016","display_name":"Wellcome / EPSRC Centre for Interventional and Surgical Sciences","ror":"https://ror.org/03r42r570","country_code":"GB","type":"facility","lineage":["https://openalex.org/I124357947","https://openalex.org/I1299528221","https://openalex.org/I4210087105","https://openalex.org/I4210122016","https://openalex.org/I45129253","https://openalex.org/I87048295"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Taimur T. Shah","raw_affiliation_strings":["Division of Surgical and Interventional SciencesUniversity College London","Division of Surgical and Interventional Sciences, University College London"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Surgical and Interventional SciencesUniversity College London","institution_ids":["https://openalex.org/I4210122016","https://openalex.org/I45129253"]},{"raw_affiliation_string":"Division of Surgical and Interventional Sciences, University College London","institution_ids":["https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008243215","display_name":"Hashim U. Ahmed","orcid":"https://orcid.org/0000-0003-1674-6723"},"institutions":[{"id":"https://openalex.org/I4210122016","display_name":"Wellcome / EPSRC Centre for Interventional and Surgical Sciences","ror":"https://ror.org/03r42r570","country_code":"GB","type":"facility","lineage":["https://openalex.org/I124357947","https://openalex.org/I1299528221","https://openalex.org/I4210087105","https://openalex.org/I4210122016","https://openalex.org/I45129253","https://openalex.org/I87048295"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Hashim U. Ahmed","raw_affiliation_strings":["Division of Surgical and Interventional SciencesUniversity College London","Division of Surgical and Interventional Sciences, University College London"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Surgical and Interventional SciencesUniversity College London","institution_ids":["https://openalex.org/I4210122016","https://openalex.org/I45129253"]},{"raw_affiliation_string":"Division of Surgical and Interventional Sciences, University College London","institution_ids":["https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056524769","display_name":"Shonit Punwani","orcid":"https://orcid.org/0000-0002-1014-0870"},"institutions":[{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Shonit Punwani","raw_affiliation_strings":["UCL Centre for Medical Imaging, Division of MedicineUniversity College London","UCL Centre for Medical Imaging, Division of Medicine, University College London"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UCL Centre for Medical Imaging, Division of MedicineUniversity College London","institution_ids":["https://openalex.org/I45129253"]},{"raw_affiliation_string":"UCL Centre for Medical Imaging, Division of Medicine, University College London","institution_ids":["https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049845313","display_name":"David J. Hawkes","orcid":"https://orcid.org/0000-0001-7151-1762"},"institutions":[{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"David J. Hawkes","raw_affiliation_strings":["UCL Centre for Medical Image Computing, Department of Medical Physics and Biomedical EngineeringUniversity College London","UCL Centre for Medical Image Computing, Department of Medical Physics and Biomedical Engineering, University College London"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UCL Centre for Medical Image Computing, Department of Medical Physics and Biomedical EngineeringUniversity College London","institution_ids":["https://openalex.org/I45129253"]},{"raw_affiliation_string":"UCL Centre for Medical Image Computing, Department of Medical Physics and Biomedical Engineering, University College London","institution_ids":["https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083172675","display_name":"Mark Emberton","orcid":"https://orcid.org/0000-0003-4230-0338"},"institutions":[{"id":"https://openalex.org/I4210122016","display_name":"Wellcome / EPSRC Centre for Interventional and Surgical Sciences","ror":"https://ror.org/03r42r570","country_code":"GB","type":"facility","lineage":["https://openalex.org/I124357947","https://openalex.org/I1299528221","https://openalex.org/I4210087105","https://openalex.org/I4210122016","https://openalex.org/I45129253","https://openalex.org/I87048295"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Mark Emberton","raw_affiliation_strings":["Division of Surgical and Interventional SciencesUniversity College London","Division of Surgical and Interventional Sciences, University College London"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Surgical and Interventional SciencesUniversity College London","institution_ids":["https://openalex.org/I4210122016","https://openalex.org/I45129253"]},{"raw_affiliation_string":"Division of Surgical and Interventional Sciences, University College London","institution_ids":["https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008343293","display_name":"Caroline M. Moore","orcid":"https://orcid.org/0000-0003-0202-7912"},"institutions":[{"id":"https://openalex.org/I4210122016","display_name":"Wellcome / EPSRC Centre for Interventional and Surgical Sciences","ror":"https://ror.org/03r42r570","country_code":"GB","type":"facility","lineage":["https://openalex.org/I124357947","https://openalex.org/I1299528221","https://openalex.org/I4210087105","https://openalex.org/I4210122016","https://openalex.org/I45129253","https://openalex.org/I87048295"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Caroline M. Moore","raw_affiliation_strings":["Division of Surgical and Interventional SciencesUniversity College London","Division of Surgical and Interventional Sciences, University College London"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Surgical and Interventional SciencesUniversity College London","institution_ids":["https://openalex.org/I4210122016","https://openalex.org/I45129253"]},{"raw_affiliation_string":"Division of Surgical and Interventional Sciences, University College London","institution_ids":["https://openalex.org/I45129253"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5066703217","display_name":"Dean C. Barratt","orcid":"https://orcid.org/0000-0003-2916-655X"},"institutions":[{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Dean C. Barratt","raw_affiliation_strings":["UCL Centre for Medical Image Computing, Department of Medical Physics and Biomedical EngineeringUniversity College London","UCL Centre for Medical Image Computing, Department of Medical Physics and Biomedical Engineering, University College London"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UCL Centre for Medical Image Computing, Department of Medical Physics and Biomedical EngineeringUniversity College London","institution_ids":["https://openalex.org/I45129253"]},{"raw_affiliation_string":"UCL Centre for Medical Image Computing, Department of Medical Physics and Biomedical Engineering, University College London","institution_ids":["https://openalex.org/I45129253"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":12,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.0502,"has_fulltext":false,"cited_by_count":17,"citation_normalized_percentile":{"value":0.77018419,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":98},"biblio":{"volume":"64","issue":"4","first_page":"946","last_page":"958"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10868","display_name":"Soft Robotics and Applications","score":0.4142000079154968,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10868","display_name":"Soft Robotics and Applications","score":0.4142000079154968,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10358","display_name":"Advanced Radiotherapy Techniques","score":0.38440001010894775,"subfield":{"id":"https://openalex.org/subfields/3108","display_name":"Radiation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10124","display_name":"Prostate Cancer Diagnosis and Treatment","score":0.04100000113248825,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ultrasound","display_name":"Ultrasound","score":0.7787566184997559},{"id":"https://openalex.org/keywords/imaging-phantom","display_name":"Imaging phantom","score":0.7533414363861084},{"id":"https://openalex.org/keywords/prostate","display_name":"Prostate","score":0.6110196113586426},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.6023281812667847},{"id":"https://openalex.org/keywords/biopsy","display_name":"Biopsy","score":0.5804502964019775},{"id":"https://openalex.org/keywords/prostate-biopsy","display_name":"Prostate biopsy","score":0.5521454215049744},{"id":"https://openalex.org/keywords/prostate-cancer","display_name":"Prostate cancer","score":0.4995265007019043},{"id":"https://openalex.org/keywords/radiology","display_name":"Radiology","score":0.4224790334701538},{"id":"https://openalex.org/keywords/biomedical-engineering","display_name":"Biomedical engineering","score":0.3411508798599243},{"id":"https://openalex.org/keywords/cancer","display_name":"Cancer","score":0.1258985996246338}],"concepts":[{"id":"https://openalex.org/C143753070","wikidata":"https://www.wikidata.org/wiki/Q162564","display_name":"Ultrasound","level":2,"score":0.7787566184997559},{"id":"https://openalex.org/C104293457","wikidata":"https://www.wikidata.org/wiki/Q28324852","display_name":"Imaging phantom","level":2,"score":0.7533414363861084},{"id":"https://openalex.org/C2776235491","wikidata":"https://www.wikidata.org/wiki/Q9625","display_name":"Prostate","level":3,"score":0.6110196113586426},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6023281812667847},{"id":"https://openalex.org/C2775934546","wikidata":"https://www.wikidata.org/wiki/Q179991","display_name":"Biopsy","level":2,"score":0.5804502964019775},{"id":"https://openalex.org/C2781217009","wikidata":"https://www.wikidata.org/wiki/Q4086927","display_name":"Prostate biopsy","level":4,"score":0.5521454215049744},{"id":"https://openalex.org/C2780192828","wikidata":"https://www.wikidata.org/wiki/Q181257","display_name":"Prostate cancer","level":3,"score":0.4995265007019043},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.4224790334701538},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.3411508798599243},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.1258985996246338},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D004867","descriptor_name":"Equipment Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004867","descriptor_name":"Equipment Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004867","descriptor_name":"Equipment Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004867","descriptor_name":"Equipment Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004867","descriptor_name":"Equipment Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007089","descriptor_name":"Image Enhancement","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D007089","descriptor_name":"Image Enhancement","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D007089","descriptor_name":"Image Enhancement","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D007089","descriptor_name":"Image Enhancement","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D007089","descriptor_name":"Image Enhancement","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D007089","descriptor_name":"Image Enhancement","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007089","descriptor_name":"Image Enhancement","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007089","descriptor_name":"Image Enhancement","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007089","descriptor_name":"Image Enhancement","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007089","descriptor_name":"Image Enhancement","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019047","descriptor_name":"Phantoms, Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019047","descriptor_name":"Phantoms, Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019047","descriptor_name":"Phantoms, Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019047","descriptor_name":"Phantoms, Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019047","descriptor_name":"Phantoms, Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019160","descriptor_name":"Endosonography","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D019160","descriptor_name":"Endosonography","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D019160","descriptor_name":"Endosonography","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D019160","descriptor_name":"Endosonography","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D019160","descriptor_name":"Endosonography","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D019160","descriptor_name":"Endosonography","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019160","descriptor_name":"Endosonography","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019160","descriptor_name":"Endosonography","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019160","descriptor_name":"Endosonography","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019160","descriptor_name":"Endosonography","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019544","descriptor_name":"Equipment Failure Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019544","descriptor_name":"Equipment Failure Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019544","descriptor_name":"Equipment Failure Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019544","descriptor_name":"Equipment Failure Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019544","descriptor_name":"Equipment Failure Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053783","descriptor_name":"Magnetic Resonance Imaging, Interventional","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D053783","descriptor_name":"Magnetic Resonance Imaging, Interventional","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D053783","descriptor_name":"Magnetic Resonance Imaging, Interventional","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D053783","descriptor_name":"Magnetic Resonance Imaging, Interventional","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D053783","descriptor_name":"Magnetic Resonance Imaging, Interventional","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D053783","descriptor_name":"Magnetic Resonance Imaging, Interventional","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D053783","descriptor_name":"Magnetic Resonance Imaging, Interventional","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D053783","descriptor_name":"Magnetic Resonance Imaging, Interventional","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D053783","descriptor_name":"Magnetic Resonance Imaging, Interventional","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D053783","descriptor_name":"Magnetic Resonance Imaging, Interventional","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D061765","descriptor_name":"Endoscopic Ultrasound-Guided Fine Needle Aspiration","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D061765","descriptor_name":"Endoscopic Ultrasound-Guided Fine Needle Aspiration","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D061765","descriptor_name":"Endoscopic Ultrasound-Guided Fine Needle Aspiration","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D061765","descriptor_name":"Endoscopic Ultrasound-Guided Fine Needle Aspiration","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D061765","descriptor_name":"Endoscopic Ultrasound-Guided Fine Needle Aspiration","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D061765","descriptor_name":"Endoscopic Ultrasound-Guided Fine Needle Aspiration","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D061765","descriptor_name":"Endoscopic Ultrasound-Guided Fine Needle Aspiration","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D061765","descriptor_name":"Endoscopic Ultrasound-Guided Fine Needle Aspiration","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D061765","descriptor_name":"Endoscopic Ultrasound-Guided Fine Needle Aspiration","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D061765","descriptor_name":"Endoscopic Ultrasound-Guided Fine Needle Aspiration","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1109/tbme.2016.2582734","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tbme.2016.2582734","pdf_url":null,"source":{"id":"https://openalex.org/S5240358","display_name":"IEEE Transactions on Biomedical Engineering","issn_l":"0018-9294","issn":["0018-9294","1558-2531"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Biomedical Engineering","raw_type":"journal-article"},{"id":"pmid:27337710","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/27337710","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE transactions on bio-medical engineering","raw_type":null},{"id":"pmh:oai:eprints.ucl.ac.uk.OAI2:1498975","is_oa":false,"landing_page_url":"https://discovery.ucl.ac.uk/id/eprint/1498975/","pdf_url":null,"source":{"id":"https://openalex.org/S4306400024","display_name":"UCL Discovery (University College London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I45129253","host_organization_name":"University College London","host_organization_lineage":["https://openalex.org/I45129253"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"   IEEE Transactions on Biomedical Engineering , 64  (4)   pp. 946-958.   (2017)      ","raw_type":"Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:5053368","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5053368","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"IEEE Trans Biomed Eng","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:5053368","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5053368","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"IEEE Trans Biomed Eng","raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.4399999976158142}],"awards":[{"id":"https://openalex.org/G376402704","display_name":null,"funder_award_id":"MR/M009092/1","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"}],"funders":[{"id":"https://openalex.org/F4320311904","display_name":"Wellcome Trust","ror":"https://ror.org/029chgv08"},{"id":"https://openalex.org/F4320319985","display_name":"Cancer Research UK","ror":"https://ror.org/054225q67"},{"id":"https://openalex.org/F4320319990","display_name":"National Institute for Health and Care Research","ror":"https://ror.org/0187kwz08"},{"id":"https://openalex.org/F4320320292","display_name":"Prostate Cancer UK","ror":"https://ror.org/04dkv6329"},{"id":"https://openalex.org/F4320334626","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":51,"referenced_works":["https://openalex.org/W1502153593","https://openalex.org/W1575814238","https://openalex.org/W1605060608","https://openalex.org/W1636584561","https://openalex.org/W1872328440","https://openalex.org/W1906917243","https://openalex.org/W1977606080","https://openalex.org/W1990854032","https://openalex.org/W1995589176","https://openalex.org/W2002791411","https://openalex.org/W2013681472","https://openalex.org/W2014582215","https://openalex.org/W2019196989","https://openalex.org/W2019558424","https://openalex.org/W2021063134","https://openalex.org/W2023989473","https://openalex.org/W2027142966","https://openalex.org/W2032789473","https://openalex.org/W2037751167","https://openalex.org/W2042744243","https://openalex.org/W2044527457","https://openalex.org/W2057775191","https://openalex.org/W2064643060","https://openalex.org/W2065001169","https://openalex.org/W2070994843","https://openalex.org/W2081830150","https://openalex.org/W2092989749","https://openalex.org/W2093941725","https://openalex.org/W2095686869","https://openalex.org/W2102854936","https://openalex.org/W2114866208","https://openalex.org/W2115895082","https://openalex.org/W2119298599","https://openalex.org/W2125014139","https://openalex.org/W2130978145","https://openalex.org/W2134793522","https://openalex.org/W2138320929","https://openalex.org/W2139989322","https://openalex.org/W2146373036","https://openalex.org/W2148234126","https://openalex.org/W2148844122","https://openalex.org/W2157814660","https://openalex.org/W2160201029","https://openalex.org/W2169328783","https://openalex.org/W2170552969","https://openalex.org/W2798381377","https://openalex.org/W4205145397","https://openalex.org/W4293409513","https://openalex.org/W6676971752","https://openalex.org/W6679562753","https://openalex.org/W6750627735"],"related_works":["https://openalex.org/W3164202441","https://openalex.org/W3015759778","https://openalex.org/W2088520467","https://openalex.org/W2075763133","https://openalex.org/W2376423713","https://openalex.org/W1583600832","https://openalex.org/W2084723631","https://openalex.org/W2566665866","https://openalex.org/W2358184952","https://openalex.org/W2936837947"],"abstract_inverted_index":{"OBJECTIVE:":[0],"Three-":[1],"and":[2,63,82,142],"four-dimensional":[3],"transrectal":[4,68],"ultrasound":[5,13,80,119],"transducers":[6,29],"are":[7,18,48],"now":[8],"available":[9],"from":[10],"most":[11],"major":[12],"equipment":[14],"manufacturers,":[15],"but":[16,37],"currently":[17],"incorporated":[19],"into":[20],"only":[21],"one":[22],"commercial":[23],"prostate":[24,69,83],"biopsy":[25,70,107,180],"guidance":[26,120,124,165],"system.":[27,129],"Such":[28],"offer":[30],"the":[31,60,79,93,99,127,163],"benefits":[32],"of":[33,65,92,171],"rapid":[34],"volumetric":[35],"imaging,":[36],"can":[38],"cause":[39],"substantial":[40],"measurement":[41],"distortion":[42],"in":[43,85,113,155],"electromagnetic":[44],"tracking":[45,76],"sensors,":[46],"which":[47],"commonly":[49],"used":[50],"to":[51,77,109],"enable":[52],"3-D":[53,86,123,164],"navigation.":[54],"In":[55],"this":[56],"paper,":[57],"we":[58],"describe":[59],"design,":[61],"development,":[62],"validation":[64],"a":[66,106,114,176],"3-D-ultrasound-guided":[67],"system":[71,94,166],"that":[72],"employs":[73],"high-accuracy":[74],"optical":[75],"localize":[78],"probe":[81],"targets":[84,112],"physical":[87],"space.":[88],"METHODS:":[89],"The":[90,131],"accuracy":[91,158],"was":[95,137,146,159],"validated":[96],"by":[97,126],"evaluating":[98],"targeted":[100],"needle":[101,108,156],"placement":[102,157],"error":[103,136],"after":[104],"inserting":[105],"sample":[110],"planned":[111],"phantom":[115],"using":[116,162,175],"standard":[117,177],"2-D":[118],"versus":[121],"real-time":[122],"provided":[125],"new":[128],"RESULTS:":[130],"overall":[132],"mean":[133,143],"needle-segment-to-target":[134],"distance":[135,145],"3.6":[138],"\u00b1":[139,148],"4.0":[140],"mm":[141],"needle-to-target":[144],"3.2":[147],"2.4":[149],"mm.":[150],"CONCLUSION:":[151],"A":[152],"significant":[153],"increase":[154],"observed":[160],"when":[161],"compared":[167],"with":[168],"visual":[169],"targeting":[170],"invisible":[172],"(virtual)":[173],"lesions":[174],"B-mode":[178],"ultrasound-guided":[179],"technique.":[181]},"counts_by_year":[{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":3},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":5}],"updated_date":"2026-06-23T13:55:30.953635","created_date":"2025-10-10T00:00:00"}