{"id":"https://openalex.org/W2075778125","doi":"https://doi.org/10.1109/tbme.2012.2187899","title":"Computational Analysis of Contractility in Engineered Heart Tissue","display_name":"Computational Analysis of Contractility in Engineered Heart Tissue","publication_year":2012,"publication_date":"2012-02-22","ids":{"openalex":"https://openalex.org/W2075778125","doi":"https://doi.org/10.1109/tbme.2012.2187899","mag":"2075778125","pmid":"https://pubmed.ncbi.nlm.nih.gov/22361653"},"language":"en","primary_location":{"id":"doi:10.1109/tbme.2012.2187899","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tbme.2012.2187899","pdf_url":null,"source":{"id":"https://openalex.org/S5240358","display_name":"IEEE Transactions on Biomedical Engineering","issn_l":"0018-9294","issn":["0018-9294","1558-2531"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Biomedical Engineering","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5022739749","display_name":"Grant Mathews","orcid":null},"institutions":[{"id":"https://openalex.org/I84218800","display_name":"University of California, Davis","ror":"https://ror.org/05rrcem69","country_code":"US","type":"education","lineage":["https://openalex.org/I84218800"]},{"id":"https://openalex.org/I95457486","display_name":"University of California, Berkeley","ror":"https://ror.org/01an7q238","country_code":"US","type":"education","lineage":["https://openalex.org/I95457486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"G. Mathews","raw_affiliation_strings":["University of California Davis School of Medicine, Department of Surgery, Division of Cardiothoracic Surgery, Sacramento, CA 95817, USA. grant.m.mathews@gmail.com","Dept. of Surg., Univ. of California, Sacramento, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of California Davis School of Medicine, Department of Surgery, Division of Cardiothoracic Surgery, Sacramento, CA 95817, USA. grant.m.mathews@gmail.com","institution_ids":["https://openalex.org/I84218800"]},{"raw_affiliation_string":"Dept. of Surg., Univ. of California, Sacramento, CA, USA","institution_ids":["https://openalex.org/I95457486"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072835716","display_name":"C. S\u00f8ndergaard","orcid":"https://orcid.org/0000-0002-3607-7814"},"institutions":[{"id":"https://openalex.org/I84218800","display_name":"University of California, Davis","ror":"https://ror.org/05rrcem69","country_code":"US","type":"education","lineage":["https://openalex.org/I84218800"]},{"id":"https://openalex.org/I95457486","display_name":"University of California, Berkeley","ror":"https://ror.org/01an7q238","country_code":"US","type":"education","lineage":["https://openalex.org/I95457486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"C. Sondergaard","raw_affiliation_strings":["Department of Surgery, Division of Cardiothoracic Surgery, Davis School of Medicine, University of California, Sacramento, CA, USA","Dept. of Surg., Univ. of California, Sacramento, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Division of Cardiothoracic Surgery, Davis School of Medicine, University of California, Sacramento, CA, USA","institution_ids":["https://openalex.org/I84218800"]},{"raw_affiliation_string":"Dept. of Surg., Univ. of California, Sacramento, CA, USA","institution_ids":["https://openalex.org/I95457486"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015869693","display_name":"Angela Jeffreys","orcid":null},"institutions":[{"id":"https://openalex.org/I84218800","display_name":"University of California, Davis","ror":"https://ror.org/05rrcem69","country_code":"US","type":"education","lineage":["https://openalex.org/I84218800"]},{"id":"https://openalex.org/I95457486","display_name":"University of California, Berkeley","ror":"https://ror.org/01an7q238","country_code":"US","type":"education","lineage":["https://openalex.org/I95457486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"A. Jeffreys","raw_affiliation_strings":["Department of Surgery, Division of Cardiothoracic Surgery, Davis School of Medicine, University of California, Sacramento, CA, USA","Dept. of Surg., Univ. of California, Sacramento, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Division of Cardiothoracic Surgery, Davis School of Medicine, University of California, Sacramento, CA, USA","institution_ids":["https://openalex.org/I84218800"]},{"raw_affiliation_string":"Dept. of Surg., Univ. of California, Sacramento, CA, USA","institution_ids":["https://openalex.org/I95457486"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111713987","display_name":"W. J. Childs","orcid":null},"institutions":[{"id":"https://openalex.org/I84218800","display_name":"University of California, Davis","ror":"https://ror.org/05rrcem69","country_code":"US","type":"education","lineage":["https://openalex.org/I84218800"]},{"id":"https://openalex.org/I95457486","display_name":"University of California, Berkeley","ror":"https://ror.org/01an7q238","country_code":"US","type":"education","lineage":["https://openalex.org/I95457486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"W. Childs","raw_affiliation_strings":["Department of Surgery, Division of Cardiothoracic Surgery, Davis School of Medicine, University of California, Sacramento, CA, USA","Dept. of Surg., Univ. of California, Sacramento, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Division of Cardiothoracic Surgery, Davis School of Medicine, University of California, Sacramento, CA, USA","institution_ids":["https://openalex.org/I84218800"]},{"raw_affiliation_string":"Dept. of Surg., Univ. of California, Sacramento, CA, USA","institution_ids":["https://openalex.org/I95457486"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100516182","display_name":"Bao Linh Le","orcid":null},"institutions":[{"id":"https://openalex.org/I84218800","display_name":"University of California, Davis","ror":"https://ror.org/05rrcem69","country_code":"US","type":"education","lineage":["https://openalex.org/I84218800"]},{"id":"https://openalex.org/I95457486","display_name":"University of California, Berkeley","ror":"https://ror.org/01an7q238","country_code":"US","type":"education","lineage":["https://openalex.org/I95457486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Bao Linh Le","raw_affiliation_strings":["Department of Surgery, Division of Cardiothoracic Surgery, Davis School of Medicine, University of California, Sacramento, CA, USA","Dept. of Surg., Univ. of California, Sacramento, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Division of Cardiothoracic Surgery, Davis School of Medicine, University of California, Sacramento, CA, USA","institution_ids":["https://openalex.org/I84218800"]},{"raw_affiliation_string":"Dept. of Surg., Univ. of California, Sacramento, CA, USA","institution_ids":["https://openalex.org/I95457486"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043048533","display_name":"Amrit Sahota","orcid":null},"institutions":[{"id":"https://openalex.org/I84218800","display_name":"University of California, Davis","ror":"https://ror.org/05rrcem69","country_code":"US","type":"education","lineage":["https://openalex.org/I84218800"]},{"id":"https://openalex.org/I95457486","display_name":"University of California, Berkeley","ror":"https://ror.org/01an7q238","country_code":"US","type":"education","lineage":["https://openalex.org/I95457486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"A. Sahota","raw_affiliation_strings":["Department of Surgery, Division of Cardiothoracic Surgery, Davis School of Medicine, University of California, Sacramento, CA, USA","Dept. of Surg., Univ. of California, Sacramento, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Division of Cardiothoracic Surgery, Davis School of Medicine, University of California, Sacramento, CA, USA","institution_ids":["https://openalex.org/I84218800"]},{"raw_affiliation_string":"Dept. of Surg., Univ. of California, Sacramento, CA, USA","institution_ids":["https://openalex.org/I95457486"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085840058","display_name":"Somayeh Najibi","orcid":null},"institutions":[{"id":"https://openalex.org/I84218800","display_name":"University of California, Davis","ror":"https://ror.org/05rrcem69","country_code":"US","type":"education","lineage":["https://openalex.org/I84218800"]},{"id":"https://openalex.org/I95457486","display_name":"University of California, Berkeley","ror":"https://ror.org/01an7q238","country_code":"US","type":"education","lineage":["https://openalex.org/I95457486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"S. Najibi","raw_affiliation_strings":["Department of Surgery, Division of Cardiothoracic Surgery, Davis School of Medicine, University of California, Sacramento, CA, USA","Dept. of Surg., Univ. of California, Sacramento, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Division of Cardiothoracic Surgery, Davis School of Medicine, University of California, Sacramento, CA, USA","institution_ids":["https://openalex.org/I84218800"]},{"raw_affiliation_string":"Dept. of Surg., Univ. of California, Sacramento, CA, USA","institution_ids":["https://openalex.org/I95457486"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085630765","display_name":"Jan A. Nolta","orcid":"https://orcid.org/0000-0003-4576-8542"},"institutions":[{"id":"https://openalex.org/I194456095","display_name":"California Institute for Regenerative Medicine","ror":"https://ror.org/033m8b439","country_code":"US","type":"government","lineage":["https://openalex.org/I194456095"]},{"id":"https://openalex.org/I84218800","display_name":"University of California, Davis","ror":"https://ror.org/05rrcem69","country_code":"US","type":"education","lineage":["https://openalex.org/I84218800"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J. Nolta","raw_affiliation_strings":["Center Institute for Regenerative Cures, School of Medicine, University of California, Davis, Sacramento, CA, USA","Inst. for Regenerative Cures, Univ. of Davis Med. Center, Sacramento, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center Institute for Regenerative Cures, School of Medicine, University of California, Davis, Sacramento, CA, USA","institution_ids":["https://openalex.org/I194456095","https://openalex.org/I84218800"]},{"raw_affiliation_string":"Inst. for Regenerative Cures, Univ. of Davis Med. Center, Sacramento, CA, USA","institution_ids":["https://openalex.org/I84218800"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5057791947","display_name":"Ming\u2010Sing Si","orcid":"https://orcid.org/0000-0002-1927-420X"},"institutions":[{"id":"https://openalex.org/I84218800","display_name":"University of California, Davis","ror":"https://ror.org/05rrcem69","country_code":"US","type":"education","lineage":["https://openalex.org/I84218800"]},{"id":"https://openalex.org/I95457486","display_name":"University of California, Berkeley","ror":"https://ror.org/01an7q238","country_code":"US","type":"education","lineage":["https://openalex.org/I95457486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M. Si","raw_affiliation_strings":["Department of Surgery, Division of Cardiothoracic Surgery, Davis School of Medicine, University of California, Sacramento, CA, USA","Dept. of Surg., Univ. of California, Sacramento, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Division of Cardiothoracic Surgery, Davis School of Medicine, University of California, Sacramento, CA, USA","institution_ids":["https://openalex.org/I84218800"]},{"raw_affiliation_string":"Dept. of Surg., Univ. of California, Sacramento, CA, USA","institution_ids":["https://openalex.org/I95457486"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":2645,"currency":"USD","value_usd":2645},"apc_paid":null,"fwci":0.5655,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.71081848,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":95},"biblio":{"volume":"59","issue":"5","first_page":"1429","last_page":"1435"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12264","display_name":"Tissue Engineering and Regenerative Medicine","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12264","display_name":"Tissue Engineering and Regenerative Medicine","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11190","display_name":"3D Printing in Biomedical Research","score":0.9901000261306763,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10729","display_name":"Electrospun Nanofibers in Biomedical Applications","score":0.9878000020980835,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/contractility","display_name":"Contractility","score":0.7344767451286316},{"id":"https://openalex.org/keywords/contraction","display_name":"Contraction (grammar)","score":0.6787517070770264},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5308915972709656},{"id":"https://openalex.org/keywords/biomedical-engineering","display_name":"Biomedical engineering","score":0.48431745171546936},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.4088418185710907},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.18327650427818298},{"id":"https://openalex.org/keywords/cardiology","display_name":"Cardiology","score":0.1767342984676361},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.1063762903213501},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.10554742813110352}],"concepts":[{"id":"https://openalex.org/C39133596","wikidata":"https://www.wikidata.org/wiki/Q5165683","display_name":"Contractility","level":2,"score":0.7344767451286316},{"id":"https://openalex.org/C163415756","wikidata":"https://www.wikidata.org/wiki/Q126473","display_name":"Contraction (grammar)","level":2,"score":0.6787517070770264},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5308915972709656},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.48431745171546936},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.4088418185710907},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.18327650427818298},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.1767342984676361},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.1063762903213501},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.10554742813110352}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001696","descriptor_name":"Biomechanical Phenomena","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D001696","descriptor_name":"Biomechanical Phenomena","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D001696","descriptor_name":"Biomechanical Phenomena","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006321","descriptor_name":"Heart","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006321","descriptor_name":"Heart","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006321","descriptor_name":"Heart","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009200","descriptor_name":"Myocardial Contraction","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009200","descriptor_name":"Myocardial Contraction","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009200","descriptor_name":"Myocardial Contraction","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009206","descriptor_name":"Myocardium","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D009206","descriptor_name":"Myocardium","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D009206","descriptor_name":"Myocardium","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D012815","descriptor_name":"Signal Processing, Computer-Assisted","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012815","descriptor_name":"Signal Processing, Computer-Assisted","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012815","descriptor_name":"Signal Processing, Computer-Assisted","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014159","descriptor_name":"Transducers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014159","descriptor_name":"Transducers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014159","descriptor_name":"Transducers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023822","descriptor_name":"Tissue Engineering","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023822","descriptor_name":"Tissue Engineering","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023822","descriptor_name":"Tissue Engineering","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1109/tbme.2012.2187899","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tbme.2012.2187899","pdf_url":null,"source":{"id":"https://openalex.org/S5240358","display_name":"IEEE Transactions on Biomedical Engineering","issn_l":"0018-9294","issn":["0018-9294","1558-2531"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Biomedical Engineering","raw_type":"journal-article"},{"id":"pmid:22361653","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22361653","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE transactions on bio-medical engineering","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.5099999904632568,"id":"https://metadata.un.org/sdg/3"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":21,"referenced_works":["https://openalex.org/W1860124109","https://openalex.org/W1967989385","https://openalex.org/W1970516435","https://openalex.org/W1970572800","https://openalex.org/W2014826453","https://openalex.org/W2026905879","https://openalex.org/W2074435319","https://openalex.org/W2085776993","https://openalex.org/W2100520149","https://openalex.org/W2143947516","https://openalex.org/W2145411235","https://openalex.org/W2156178494","https://openalex.org/W2159772818","https://openalex.org/W2160749035","https://openalex.org/W2163660141","https://openalex.org/W2170823241","https://openalex.org/W2171313781","https://openalex.org/W3008306360","https://openalex.org/W6675253924","https://openalex.org/W6682860807","https://openalex.org/W6684032805"],"related_works":["https://openalex.org/W2748952813","https://openalex.org/W2374723269","https://openalex.org/W1992418884","https://openalex.org/W2992096461","https://openalex.org/W4246159840","https://openalex.org/W2334838563","https://openalex.org/W2046678612","https://openalex.org/W2369922294","https://openalex.org/W4211249856","https://openalex.org/W2382983477"],"abstract_inverted_index":{"Engineered":[0],"heart":[1,9],"tissue":[2],"(EHT)":[3],"is":[4,45,57,64,160],"a":[5,40,46,79,161],"potential":[6],"therapy":[7],"for":[8],"failure":[10],"and":[11,68,84,98,102,116,134,143,167],"the":[12,33,71,107,165],"basis":[13],"of":[14,19,35,49,53,73,131,170],"functional":[15],"in":[16,28,112,128],"vitro":[17],"assays":[18],"novel":[20],"cardiovascular":[21],"treatments.":[22],"Self-organizing":[23],"EHT":[24,50,54,87,171],"can":[25],"be":[26,110],"generated":[27],"fiber":[29],"form,":[30],"which":[31],"makes":[32],"assessment":[34,169],"contractile":[36,146,172],"function":[37,44],"convenient":[38],"with":[39],"force":[41,55,88,152],"transducer.":[42],"Contractile":[43],"key":[47,162],"parameter":[48],"performance.":[51],"Analysis":[52],"data":[56,93,132],"often":[58],"performed":[59],"manually;":[60],"however,":[61],"this":[62,74,157],"approach":[63],"time":[65],"consuming,":[66],"incomplete":[67],"subjective.":[69],"Therefore,":[70],"purpose":[72],"study":[75],"was":[76,126,135],"to":[77,82,109,121,137,164],"develop":[78],"computer":[80,158],"algorithm":[81,91,108,125,159],"efficiently":[83],"objectively":[85],"analyze":[86],"data.":[89],"This":[90],"incorporates":[92],"filtering,":[94],"individual":[95],"contraction":[96,113],"detection":[97],"validation,":[99],"inter/intracontractile":[100],"analysis":[101],"intersample":[103],"analysis.":[104],"We":[105,154],"found":[106],"accurate":[111],"detection,":[114],"validation":[115],"magnitude":[117],"measurement":[118],"as":[119,149],"compared":[120],"human":[122],"operators.":[123],"The":[124],"efficient":[127,168],"processing":[129],"hundreds":[130],"acquisitions":[133],"able":[136],"determine":[138],"force-length":[139],"curves,":[140],"force-frequency":[141],"relationships":[142],"compare":[144],"various":[145],"parameters":[147],"such":[148],"peak":[150],"systolic":[151],"generation.":[153],"conclude":[155],"that":[156],"adjunct":[163],"objective":[166],"function.":[173]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-08-21T09:56:20.448147","created_date":"2025-10-10T00:00:00"}