{"id":"https://openalex.org/W2084627109","doi":"https://doi.org/10.1109/tbme.2012.2183367","title":"Novel Speech Signal Processing Algorithms for High-Accuracy Classification of Parkinson's Disease","display_name":"Novel Speech Signal Processing Algorithms for High-Accuracy Classification of Parkinson's Disease","publication_year":2012,"publication_date":"2012-01-09","ids":{"openalex":"https://openalex.org/W2084627109","doi":"https://doi.org/10.1109/tbme.2012.2183367","mag":"2084627109"},"language":"en","primary_location":{"id":"doi:10.1109/tbme.2012.2183367","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tbme.2012.2183367","pdf_url":null,"source":{"id":"https://openalex.org/S5240358","display_name":"IEEE Transactions on Biomedical Engineering","issn_l":"0018-9294","issn":["0018-9294","1558-2531"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Biomedical Engineering","raw_type":"journal-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://publications.aston.ac.uk/id/eprint/18329/1/Novel_speech_signal_processing_algorithms.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5076281912","display_name":"Athanasios Tsanas","orcid":"https://orcid.org/0000-0002-0994-8100"},"institutions":[{"id":"https://openalex.org/I4210146410","display_name":"Science Oxford","ror":"https://ror.org/04j8yhy50","country_code":"GB","type":"nonprofit","lineage":["https://openalex.org/I4210146410"]},{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"A. Tsanas","raw_affiliation_strings":["Systems Analysis Modelling and Prediction (SAMP) Group, Department of Engineering Science, University of Oxford, Oxford, UK","Oxford Centre for Ind. & Appl. Math. (OCIAM), Univ. of Oxford, Oxford, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Systems Analysis Modelling and Prediction (SAMP) Group, Department of Engineering Science, University of Oxford, Oxford, UK","institution_ids":["https://openalex.org/I4210146410"]},{"raw_affiliation_string":"Oxford Centre for Ind. & Appl. Math. (OCIAM), Univ. of Oxford, Oxford, UK","institution_ids":["https://openalex.org/I40120149"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018028924","display_name":"Max A. Little","orcid":"https://orcid.org/0000-0002-1507-3822"},"institutions":[{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["GB","US"],"is_corresponding":false,"raw_author_name":"M. A. Little","raw_affiliation_strings":["Department of Physics, University of Oxford, Oxford, UK","Media Laboratory, Massachusetts Institute of Technology, Cambridge, MA, USA","Media Lab, Massachusetts Institute of Technology Cambridge, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physics, University of Oxford, Oxford, UK","institution_ids":["https://openalex.org/I40120149"]},{"raw_affiliation_string":"Media Laboratory, Massachusetts Institute of Technology, Cambridge, MA, USA","institution_ids":["https://openalex.org/I63966007"]},{"raw_affiliation_string":"Media Lab, Massachusetts Institute of Technology Cambridge, MA, USA","institution_ids":["https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053305605","display_name":"Patrick McSharry","orcid":"https://orcid.org/0000-0003-4663-970X"},"institutions":[{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"P. E. McSharry","raw_affiliation_strings":["University of Oxford, Oxford, Oxfordshire, GB","Smith Sch. of Enterprise & the Environ., Univ. of Oxford, Oxford, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Oxford, Oxford, Oxfordshire, GB","institution_ids":["https://openalex.org/I40120149"]},{"raw_affiliation_string":"Smith Sch. of Enterprise & the Environ., Univ. of Oxford, Oxford, UK","institution_ids":["https://openalex.org/I40120149"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065873175","display_name":"Jennifer Spielman","orcid":null},"institutions":[{"id":"https://openalex.org/I2800776452","display_name":"Denver Center for the Performing Arts","ror":"https://ror.org/00h74hd82","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I2800776452"]},{"id":"https://openalex.org/I188538660","display_name":"University of Colorado Boulder","ror":"https://ror.org/02ttsq026","country_code":"US","type":"education","lineage":["https://openalex.org/I188538660"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J. Spielman","raw_affiliation_strings":["Department of Speech, Language, and Hearing Science, University of Colorado, Boulder, CO, USA","National Center for Voice and Speech, Denver, CO, USA","Dept. of Speech, Language, & Hearing Sci., Univ. of Colorado, Boulder, CO, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Speech, Language, and Hearing Science, University of Colorado, Boulder, CO, USA","institution_ids":["https://openalex.org/I188538660"]},{"raw_affiliation_string":"National Center for Voice and Speech, Denver, CO, USA","institution_ids":["https://openalex.org/I2800776452"]},{"raw_affiliation_string":"Dept. of Speech, Language, & Hearing Sci., Univ. of Colorado, Boulder, CO, USA","institution_ids":["https://openalex.org/I188538660"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5048997233","display_name":"Lorraine O. Ramig","orcid":"https://orcid.org/0000-0002-6091-634X"},"institutions":[{"id":"https://openalex.org/I2800776452","display_name":"Denver Center for the Performing Arts","ror":"https://ror.org/00h74hd82","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I2800776452"]},{"id":"https://openalex.org/I188538660","display_name":"University of Colorado Boulder","ror":"https://ror.org/02ttsq026","country_code":"US","type":"education","lineage":["https://openalex.org/I188538660"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"L. O. Ramig","raw_affiliation_strings":["Department of Speech, Language, and Hearing Science, University of Colorado, Boulder, CO, USA","National Center for Voice and Speech, Denver, CO, USA","Dept. of Speech, Language, & Hearing Sci., Univ. of Colorado, Boulder, CO, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Speech, Language, and Hearing Science, University of Colorado, Boulder, CO, USA","institution_ids":["https://openalex.org/I188538660"]},{"raw_affiliation_string":"National Center for Voice and Speech, Denver, CO, USA","institution_ids":["https://openalex.org/I2800776452"]},{"raw_affiliation_string":"Dept. of Speech, Language, & Hearing Sci., Univ. of Colorado, Boulder, CO, USA","institution_ids":["https://openalex.org/I188538660"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5076281912"],"corresponding_institution_ids":["https://openalex.org/I40120149","https://openalex.org/I4210146410"],"apc_list":null,"apc_paid":null,"fwci":15.5352,"has_fulltext":true,"cited_by_count":715,"citation_normalized_percentile":{"value":0.99491349,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"59","issue":"5","first_page":"1264","last_page":"1271"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10863","display_name":"Voice and Speech Disorders","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10863","display_name":"Voice and Speech Disorders","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10860","display_name":"Speech and Audio Processing","score":0.9955000281333923,"subfield":{"id":"https://openalex.org/subfields/1711","display_name":"Signal Processing"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10201","display_name":"Speech Recognition and Synthesis","score":0.9944000244140625,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/statistical-classification","display_name":"Statistical classification","score":0.615210235118866},{"id":"https://openalex.org/keywords/feature-selection","display_name":"Feature selection","score":0.5912019610404968},{"id":"https://openalex.org/keywords/random-forest","display_name":"Random forest","score":0.5874820947647095},{"id":"https://openalex.org/keywords/binary-classification","display_name":"Binary classification","score":0.5802221894264221},{"id":"https://openalex.org/keywords/feature","display_name":"Feature (linguistics)","score":0.5371900796890259},{"id":"https://openalex.org/keywords/support-vector-machine","display_name":"Support vector machine","score":0.5189313888549805},{"id":"https://openalex.org/keywords/speech-processing","display_name":"Speech processing","score":0.5015418529510498},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.4964941143989563},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.480981707572937},{"id":"https://openalex.org/keywords/speech-recognition","display_name":"Speech recognition","score":0.4777597486972809},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.44802460074424744},{"id":"https://openalex.org/keywords/feature-extraction","display_name":"Feature extraction","score":0.42508378624916077},{"id":"https://openalex.org/keywords/signal-processing","display_name":"Signal processing","score":0.4120192527770996},{"id":"https://openalex.org/keywords/feature-vector","display_name":"Feature vector","score":0.41181111335754395},{"id":"https://openalex.org/keywords/digital-signal-processing","display_name":"Digital signal processing","score":0.10200676321983337}],"concepts":[{"id":"https://openalex.org/C110083411","wikidata":"https://www.wikidata.org/wiki/Q1744628","display_name":"Statistical classification","level":2,"score":0.615210235118866},{"id":"https://openalex.org/C148483581","wikidata":"https://www.wikidata.org/wiki/Q446488","display_name":"Feature selection","level":2,"score":0.5912019610404968},{"id":"https://openalex.org/C169258074","wikidata":"https://www.wikidata.org/wiki/Q245748","display_name":"Random forest","level":2,"score":0.5874820947647095},{"id":"https://openalex.org/C66905080","wikidata":"https://www.wikidata.org/wiki/Q17005494","display_name":"Binary classification","level":3,"score":0.5802221894264221},{"id":"https://openalex.org/C2776401178","wikidata":"https://www.wikidata.org/wiki/Q12050496","display_name":"Feature (linguistics)","level":2,"score":0.5371900796890259},{"id":"https://openalex.org/C12267149","wikidata":"https://www.wikidata.org/wiki/Q282453","display_name":"Support vector machine","level":2,"score":0.5189313888549805},{"id":"https://openalex.org/C61328038","wikidata":"https://www.wikidata.org/wiki/Q3358061","display_name":"Speech processing","level":2,"score":0.5015418529510498},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4964941143989563},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.480981707572937},{"id":"https://openalex.org/C28490314","wikidata":"https://www.wikidata.org/wiki/Q189436","display_name":"Speech recognition","level":1,"score":0.4777597486972809},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.44802460074424744},{"id":"https://openalex.org/C52622490","wikidata":"https://www.wikidata.org/wiki/Q1026626","display_name":"Feature extraction","level":2,"score":0.42508378624916077},{"id":"https://openalex.org/C104267543","wikidata":"https://www.wikidata.org/wiki/Q208163","display_name":"Signal processing","level":3,"score":0.4120192527770996},{"id":"https://openalex.org/C83665646","wikidata":"https://www.wikidata.org/wiki/Q42139305","display_name":"Feature vector","level":2,"score":0.41181111335754395},{"id":"https://openalex.org/C84462506","wikidata":"https://www.wikidata.org/wiki/Q173142","display_name":"Digital signal processing","level":2,"score":0.10200676321983337},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.0},{"id":"https://openalex.org/C9390403","wikidata":"https://www.wikidata.org/wiki/Q3966","display_name":"Computer hardware","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1109/tbme.2012.2183367","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tbme.2012.2183367","pdf_url":null,"source":{"id":"https://openalex.org/S5240358","display_name":"IEEE Transactions on Biomedical Engineering","issn_l":"0018-9294","issn":["0018-9294","1558-2531"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Biomedical Engineering","raw_type":"journal-article"},{"id":"pmh:oai:publications.aston.ac.uk:18329","is_oa":true,"landing_page_url":"https://publications.aston.ac.uk/view/author/55854151225fae1984fe9ab94da9b586.html>,","pdf_url":"https://publications.aston.ac.uk/id/eprint/18329/1/Novel_speech_signal_processing_algorithms.pdf","source":{"id":"https://openalex.org/S4306400483","display_name":"Aston Publications Explorer (Aston University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I169199633","host_organization_name":"Aston University","host_organization_lineage":["https://openalex.org/I169199633"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"PeerReviewed"}],"best_oa_location":{"id":"pmh:oai:publications.aston.ac.uk:18329","is_oa":true,"landing_page_url":"https://publications.aston.ac.uk/view/author/55854151225fae1984fe9ab94da9b586.html>,","pdf_url":"https://publications.aston.ac.uk/id/eprint/18329/1/Novel_speech_signal_processing_algorithms.pdf","source":{"id":"https://openalex.org/S4306400483","display_name":"Aston Publications Explorer (Aston University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I169199633","host_organization_name":"Aston University","host_organization_lineage":["https://openalex.org/I169199633"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"PeerReviewed"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/10","display_name":"Reduced inequalities","score":0.6700000166893005}],"awards":[],"funders":[{"id":"https://openalex.org/F4320307102","display_name":"Intel Corporation","ror":"https://ror.org/01ek73717"},{"id":"https://openalex.org/F4320311904","display_name":"Wellcome Trust","ror":"https://ror.org/029chgv08"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320334627","display_name":"Engineering and Physical Sciences Research Council","ror":"https://ror.org/0439y7842"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2084627109.pdf","grobid_xml":"https://content.openalex.org/works/W2084627109.grobid-xml"},"referenced_works_count":49,"referenced_works":["https://openalex.org/W1509988890","https://openalex.org/W1544215838","https://openalex.org/W1554944419","https://openalex.org/W1583700199","https://openalex.org/W1904981141","https://openalex.org/W1922017469","https://openalex.org/W1963664254","https://openalex.org/W1969285471","https://openalex.org/W1971243715","https://openalex.org/W1987349122","https://openalex.org/W2006199542","https://openalex.org/W2007221293","https://openalex.org/W2015932775","https://openalex.org/W2032655680","https://openalex.org/W2055387057","https://openalex.org/W2061386271","https://openalex.org/W2075987325","https://openalex.org/W2076723282","https://openalex.org/W2094410714","https://openalex.org/W2100534701","https://openalex.org/W2104953067","https://openalex.org/W2106821521","https://openalex.org/W2109842006","https://openalex.org/W2109943925","https://openalex.org/W2112765817","https://openalex.org/W2114147096","https://openalex.org/W2119862467","https://openalex.org/W2131822674","https://openalex.org/W2135046866","https://openalex.org/W2148830179","https://openalex.org/W2148969844","https://openalex.org/W2153635508","https://openalex.org/W2154029067","https://openalex.org/W2154036191","https://openalex.org/W2154053567","https://openalex.org/W2155295839","https://openalex.org/W2162109146","https://openalex.org/W2166361453","https://openalex.org/W2170517798","https://openalex.org/W2171033594","https://openalex.org/W2743615060","https://openalex.org/W2911964244","https://openalex.org/W3005335434","https://openalex.org/W3106266785","https://openalex.org/W3159810078","https://openalex.org/W3216401400","https://openalex.org/W4205699531","https://openalex.org/W6639690637","https://openalex.org/W6682567057"],"related_works":["https://openalex.org/W1980222719","https://openalex.org/W3011239835","https://openalex.org/W2034680797","https://openalex.org/W4207040723","https://openalex.org/W2967426019","https://openalex.org/W2990537558","https://openalex.org/W3210752578","https://openalex.org/W2621610018","https://openalex.org/W4372055028","https://openalex.org/W2165299150"],"abstract_inverted_index":{"There":[0],"has":[1],"been":[2,37],"considerable":[3],"recent":[4],"research":[5],"into":[6],"the":[7,143,153,156],"connection":[8],"between":[9],"Parkinson's":[10],"disease":[11],"(PD)":[12],"and":[13,84,100,116],"speech":[14,21,34],"impairment.":[15],"Recently,":[16],"a":[17,90],"wide":[18],"range":[19],"of":[20,75,110,142,155],"signal":[22],"processing":[23],"algorithms":[24,48,150],"(dysphonia":[25],"measures)":[26],"aiming":[27],"to":[28,52,89,158],"predict":[29],"PD":[30,54,163],"symptom":[31],"severity":[32],"using":[33,79,94,133],"signals":[35],"have":[36],"introduced.":[38],"In":[39,59],"this":[40],"paper,":[41],"we":[42,61,70],"test":[43],"how":[44],"accurately":[45],"these":[46,76,86,119,167],"novel":[47],"can":[49,123],"be":[50],"used":[51],"discriminate":[53,159],"subjects":[55],"from":[56,66,113,162],"healthy":[57,160],"controls.":[58],"total,":[60],"compute":[62],"132":[63],"dysphonia":[64,77,121,136,146],"measures":[65,78,122,147],"sustained":[67],"vowels.":[68],"Then,":[69],"select":[71],"four":[72,80],"parsimonious":[73],"subsets":[74,88],"feature":[81,87],"selection":[82],"algorithms,":[83],"map":[85],"binary":[91],"classification":[92,131],"response":[93],"two":[95],"statistical":[96],"classifiers:":[97],"random":[98],"forests":[99],"support":[101,177],"vector":[102],"machines.":[103],"We":[104,138,165],"use":[105],"an":[106,170],"existing":[107,149],"database":[108],"consisting":[109],"263":[111],"samples":[112],"43":[114],"subjects,":[115],"demonstrate":[117],"that":[118,140],"new":[120],"outperform":[124],"state-of-the-art":[125],"results,":[126],"reaching":[127],"almost":[128],"99%":[129],"overall":[130],"accuracy":[132],"only":[134],"ten":[135],"features.":[137],"find":[139],"some":[141],"recently":[144],"proposed":[145],"complement":[148],"in":[151,178],"maximizing":[152],"ability":[154],"classifiers":[157],"controls":[161],"subjects.":[164],"see":[166],"results":[168],"as":[169],"important":[171],"step":[172],"toward":[173],"noninvasive":[174],"diagnostic":[175],"decision":[176],"PD.":[179]},"counts_by_year":[{"year":2026,"cited_by_count":16},{"year":2025,"cited_by_count":62},{"year":2024,"cited_by_count":43},{"year":2023,"cited_by_count":75},{"year":2022,"cited_by_count":66},{"year":2021,"cited_by_count":88},{"year":2020,"cited_by_count":77},{"year":2019,"cited_by_count":60},{"year":2018,"cited_by_count":59},{"year":2017,"cited_by_count":40},{"year":2016,"cited_by_count":38},{"year":2015,"cited_by_count":39},{"year":2014,"cited_by_count":24},{"year":2013,"cited_by_count":21},{"year":2012,"cited_by_count":7}],"updated_date":"2026-05-07T13:39:58.223016","created_date":"2016-06-24T00:00:00"}
