{"id":"https://openalex.org/W2036885968","doi":"https://doi.org/10.1109/tbme.2011.2182195","title":"Single-Channel Blind Estimation of Arterial Input Function and Tissue Impulse Response in DCE-MRI","display_name":"Single-Channel Blind Estimation of Arterial Input Function and Tissue Impulse Response in DCE-MRI","publication_year":2012,"publication_date":"2012-01-04","ids":{"openalex":"https://openalex.org/W2036885968","doi":"https://doi.org/10.1109/tbme.2011.2182195","mag":"2036885968","pmid":"https://pubmed.ncbi.nlm.nih.gov/22217906"},"language":"en","primary_location":{"id":"doi:10.1109/tbme.2011.2182195","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tbme.2011.2182195","pdf_url":null,"source":{"id":"https://openalex.org/S5240358","display_name":"IEEE Transactions on Biomedical Engineering","issn_l":"0018-9294","issn":["0018-9294","1558-2531"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Biomedical Engineering","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5045982276","display_name":"Torfinn Taxt","orcid":null},"institutions":[{"id":"https://openalex.org/I2800740805","display_name":"Haukeland University Hospital","ror":"https://ror.org/03np4e098","country_code":"NO","type":"healthcare","lineage":["https://openalex.org/I2800740805"]},{"id":"https://openalex.org/I4432739","display_name":"University of Bergen","ror":"https://ror.org/03zga2b32","country_code":"NO","type":"education","lineage":["https://openalex.org/I4432739"]}],"countries":["NO"],"is_corresponding":true,"raw_author_name":"T. Taxt","raw_affiliation_strings":["Department of Biomedicine, University of Bergen, Bergen, Norway. torfinn.taxt@biomed.uib.no","Department of Radiology, Haukeland University Hospital, Bergen, Norway","Department of Biomedicine, University of Bergen, Bergen, Norway"],"affiliations":[{"raw_affiliation_string":"Department of Biomedicine, University of Bergen, Bergen, Norway. torfinn.taxt@biomed.uib.no","institution_ids":["https://openalex.org/I4432739"]},{"raw_affiliation_string":"Department of Radiology, Haukeland University Hospital, Bergen, Norway","institution_ids":["https://openalex.org/I2800740805"]},{"raw_affiliation_string":"Department of Biomedicine, University of Bergen, Bergen, Norway","institution_ids":["https://openalex.org/I4432739"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055323289","display_name":"Radovan Ji\u0159\u00edk","orcid":"https://orcid.org/0000-0003-2555-9428"},"institutions":[{"id":"https://openalex.org/I60587646","display_name":"Brno University of Technology","ror":"https://ror.org/03613d656","country_code":"CZ","type":"education","lineage":["https://openalex.org/I60587646"]},{"id":"https://openalex.org/I4210124512","display_name":"Czech Academy of Sciences, Institute of Scientific Instruments","ror":"https://ror.org/027taah18","country_code":"CZ","type":"facility","lineage":["https://openalex.org/I202391551","https://openalex.org/I4210124512"]}],"countries":["CZ"],"is_corresponding":false,"raw_author_name":"R. Jir\u00edk","raw_affiliation_strings":["Academy of Sciences of the Czech Republic, Institute of Scientific Instruments, Prague 1, Czech Republic","Department of Biomedical Engineering, Brno University of Technology, Brno, Czech Republic"],"affiliations":[{"raw_affiliation_string":"Academy of Sciences of the Czech Republic, Institute of Scientific Instruments, Prague 1, Czech Republic","institution_ids":["https://openalex.org/I4210124512"]},{"raw_affiliation_string":"Department of Biomedical Engineering, Brno University of Technology, Brno, Czech Republic","institution_ids":["https://openalex.org/I60587646"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009627873","display_name":"Cecilie Brekke Rygh","orcid":null},"institutions":[{"id":"https://openalex.org/I4432739","display_name":"University of Bergen","ror":"https://ror.org/03zga2b32","country_code":"NO","type":"education","lineage":["https://openalex.org/I4432739"]}],"countries":["NO"],"is_corresponding":false,"raw_author_name":"C. B. Rygh","raw_affiliation_strings":["Department of Biomedicine, University of Bergen, Bergen, Norway"],"affiliations":[{"raw_affiliation_string":"Department of Biomedicine, University of Bergen, Bergen, Norway","institution_ids":["https://openalex.org/I4432739"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052870289","display_name":"Renate Gr\u00fcner","orcid":"https://orcid.org/0000-0003-1778-5433"},"institutions":[{"id":"https://openalex.org/I4432739","display_name":"University of Bergen","ror":"https://ror.org/03zga2b32","country_code":"NO","type":"education","lineage":["https://openalex.org/I4432739"]}],"countries":["NO"],"is_corresponding":false,"raw_author_name":"R. Gruner","raw_affiliation_strings":["Department of Biomedicine and Department of Physics and Technology, University of Bergen, Bergen, Norwayxs"],"affiliations":[{"raw_affiliation_string":"Department of Biomedicine and Department of Physics and Technology, University of Bergen, Bergen, Norwayxs","institution_ids":["https://openalex.org/I4432739"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022362849","display_name":"Michal Barto\u0161","orcid":"https://orcid.org/0000-0003-4389-7703"},"institutions":[{"id":"https://openalex.org/I60587646","display_name":"Brno University of Technology","ror":"https://ror.org/03613d656","country_code":"CZ","type":"education","lineage":["https://openalex.org/I60587646"]}],"countries":["CZ"],"is_corresponding":false,"raw_author_name":"M. Bartos","raw_affiliation_strings":["Department of Biomedical Engineering, Brno University of Technology, Brno, Czech Republic"],"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, Brno University of Technology, Brno, Czech Republic","institution_ids":["https://openalex.org/I60587646"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075207555","display_name":"Erling Andersen","orcid":"https://orcid.org/0000-0001-8268-1206"},"institutions":[{"id":"https://openalex.org/I2800740805","display_name":"Haukeland University Hospital","ror":"https://ror.org/03np4e098","country_code":"NO","type":"healthcare","lineage":["https://openalex.org/I2800740805"]}],"countries":["NO"],"is_corresponding":false,"raw_author_name":"E. Andersen","raw_affiliation_strings":["Department of Clinical Engineering, Haukeland University Hospital, Bergen, Norway"],"affiliations":[{"raw_affiliation_string":"Department of Clinical Engineering, Haukeland University Hospital, Bergen, Norway","institution_ids":["https://openalex.org/I2800740805"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111523425","display_name":"Fitz Roy E. Curry","orcid":null},"institutions":[{"id":"https://openalex.org/I84218800","display_name":"University of California, Davis","ror":"https://ror.org/05rrcem69","country_code":"US","type":"education","lineage":["https://openalex.org/I84218800"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"F. R. Curry","raw_affiliation_strings":["Department of Physiology and Membrane Biology, University of California, Davis, CA, USA"],"affiliations":[{"raw_affiliation_string":"Department of Physiology and Membrane Biology, University of California, Davis, CA, USA","institution_ids":["https://openalex.org/I84218800"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5076295543","display_name":"Rolf K. Reed","orcid":"https://orcid.org/0000-0002-2633-6595"},"institutions":[{"id":"https://openalex.org/I4432739","display_name":"University of Bergen","ror":"https://ror.org/03zga2b32","country_code":"NO","type":"education","lineage":["https://openalex.org/I4432739"]}],"countries":["NO"],"is_corresponding":false,"raw_author_name":"R. K. Reed","raw_affiliation_strings":["Department of Biomedicine, University of Bergen, Bergen, Norway"],"affiliations":[{"raw_affiliation_string":"Department of Biomedicine, University of Bergen, Bergen, Norway","institution_ids":["https://openalex.org/I4432739"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5045982276"],"corresponding_institution_ids":["https://openalex.org/I2800740805","https://openalex.org/I4432739"],"apc_list":null,"apc_paid":null,"fwci":2.7395,"has_fulltext":false,"cited_by_count":29,"citation_normalized_percentile":{"value":0.89413718,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"59","issue":"4","first_page":"1012","last_page":"1021"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11885","display_name":"MRI in cancer diagnosis","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11885","display_name":"MRI in cancer diagnosis","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10378","display_name":"Advanced MRI Techniques and Applications","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11304","display_name":"Advanced Neuroimaging Techniques and Applications","score":0.9972000122070312,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/deconvolution","display_name":"Deconvolution","score":0.8902428150177002},{"id":"https://openalex.org/keywords/impulse-response","display_name":"Impulse response","score":0.7303770184516907},{"id":"https://openalex.org/keywords/blind-deconvolution","display_name":"Blind deconvolution","score":0.6608532667160034},{"id":"https://openalex.org/keywords/impulse","display_name":"Impulse (physics)","score":0.5591464042663574},{"id":"https://openalex.org/keywords/biomedical-engineering","display_name":"Biomedical engineering","score":0.5041631460189819},{"id":"https://openalex.org/keywords/transfer-function","display_name":"Transfer function","score":0.47000107169151306},{"id":"https://openalex.org/keywords/tracer","display_name":"TRACER","score":0.4478250741958618},{"id":"https://openalex.org/keywords/function","display_name":"Function (biology)","score":0.41916143894195557},{"id":"https://openalex.org/keywords/biological-system","display_name":"Biological system","score":0.41601794958114624},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.3707349896430969},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.30897384881973267},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.25532716512680054},{"id":"https://openalex.org/keywords/mathematical-analysis","display_name":"Mathematical analysis","score":0.22948595881462097},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.13755926489830017}],"concepts":[{"id":"https://openalex.org/C174576160","wikidata":"https://www.wikidata.org/wiki/Q1183700","display_name":"Deconvolution","level":2,"score":0.8902428150177002},{"id":"https://openalex.org/C72279823","wikidata":"https://www.wikidata.org/wiki/Q1139726","display_name":"Impulse response","level":2,"score":0.7303770184516907},{"id":"https://openalex.org/C30044814","wikidata":"https://www.wikidata.org/wiki/Q11334452","display_name":"Blind deconvolution","level":3,"score":0.6608532667160034},{"id":"https://openalex.org/C70836080","wikidata":"https://www.wikidata.org/wiki/Q837940","display_name":"Impulse (physics)","level":2,"score":0.5591464042663574},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.5041631460189819},{"id":"https://openalex.org/C81299745","wikidata":"https://www.wikidata.org/wiki/Q334269","display_name":"Transfer function","level":2,"score":0.47000107169151306},{"id":"https://openalex.org/C2778863792","wikidata":"https://www.wikidata.org/wiki/Q16909918","display_name":"TRACER","level":2,"score":0.4478250741958618},{"id":"https://openalex.org/C14036430","wikidata":"https://www.wikidata.org/wiki/Q3736076","display_name":"Function (biology)","level":2,"score":0.41916143894195557},{"id":"https://openalex.org/C186060115","wikidata":"https://www.wikidata.org/wiki/Q30336093","display_name":"Biological system","level":1,"score":0.41601794958114624},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.3707349896430969},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.30897384881973267},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.25532716512680054},{"id":"https://openalex.org/C134306372","wikidata":"https://www.wikidata.org/wiki/Q7754","display_name":"Mathematical analysis","level":1,"score":0.22948595881462097},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.13755926489830017},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C119599485","wikidata":"https://www.wikidata.org/wiki/Q43035","display_name":"Electrical engineering","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C78458016","wikidata":"https://www.wikidata.org/wiki/Q840400","display_name":"Evolutionary biology","level":1,"score":0.0},{"id":"https://openalex.org/C185544564","wikidata":"https://www.wikidata.org/wiki/Q81197","display_name":"Nuclear physics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001158","descriptor_name":"Arteries","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D001158","descriptor_name":"Arteries","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D001158","descriptor_name":"Arteries","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D001783","descriptor_name":"Blood Flow Velocity","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D001783","descriptor_name":"Blood Flow Velocity","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D001783","descriptor_name":"Blood Flow Velocity","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003287","descriptor_name":"Contrast Media","qualifier_ui":"Q000493","qualifier_name":"pharmacokinetics","is_major_topic":false},{"descriptor_ui":"D003287","descriptor_name":"Contrast Media","qualifier_ui":"Q000493","qualifier_name":"pharmacokinetics","is_major_topic":false},{"descriptor_ui":"D003287","descriptor_name":"Contrast Media","qualifier_ui":"Q000493","qualifier_name":"pharmacokinetics","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007089","descriptor_name":"Image Enhancement","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007089","descriptor_name":"Image Enhancement","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007089","descriptor_name":"Image Enhancement","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007090","descriptor_name":"Image Interpretation, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007090","descriptor_name":"Image Interpretation, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007090","descriptor_name":"Image Interpretation, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008810","descriptor_name":"Mice, Inbred C57BL","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008810","descriptor_name":"Mice, Inbred C57BL","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008810","descriptor_name":"Mice, Inbred C57BL","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015233","descriptor_name":"Models, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015233","descriptor_name":"Models, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015233","descriptor_name":"Models, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000098","qualifier_name":"blood supply","is_major_topic":false},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000098","qualifier_name":"blood supply","is_major_topic":false},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000098","qualifier_name":"blood supply","is_major_topic":false},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D018810","descriptor_name":"Magnetic Resonance Angiography","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D018810","descriptor_name":"Magnetic Resonance Angiography","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D018810","descriptor_name":"Magnetic Resonance Angiography","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019786","descriptor_name":"Gadolinium DTPA","qualifier_ui":"Q000493","qualifier_name":"pharmacokinetics","is_major_topic":false},{"descriptor_ui":"D019786","descriptor_name":"Gadolinium DTPA","qualifier_ui":"Q000493","qualifier_name":"pharmacokinetics","is_major_topic":false},{"descriptor_ui":"D019786","descriptor_name":"Gadolinium DTPA","qualifier_ui":"Q000493","qualifier_name":"pharmacokinetics","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1109/tbme.2011.2182195","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tbme.2011.2182195","pdf_url":null,"source":{"id":"https://openalex.org/S5240358","display_name":"IEEE Transactions on Biomedical Engineering","issn_l":"0018-9294","issn":["0018-9294","1558-2531"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Biomedical Engineering","raw_type":"journal-article"},{"id":"pmid:22217906","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22217906","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE transactions on bio-medical engineering","raw_type":null},{"id":"pmh:oai:asep.lib.cas.cz:CavUnEpca/0385359","is_oa":false,"landing_page_url":"http://hdl.handle.net/11104/0214631","pdf_url":null,"source":{"id":"https://openalex.org/S7407055266","display_name":"ASEP","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/publishedVersion"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.550000011920929,"display_name":"Good health and well-being"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":45,"referenced_works":["https://openalex.org/W1606592749","https://openalex.org/W1638241823","https://openalex.org/W1965345052","https://openalex.org/W1977355015","https://openalex.org/W1978617007","https://openalex.org/W1983446930","https://openalex.org/W1983558702","https://openalex.org/W1987512176","https://openalex.org/W1988037252","https://openalex.org/W1996331485","https://openalex.org/W1999614991","https://openalex.org/W2001974555","https://openalex.org/W2004686146","https://openalex.org/W2011687187","https://openalex.org/W2017988743","https://openalex.org/W2020111712","https://openalex.org/W2026223125","https://openalex.org/W2031753563","https://openalex.org/W2034724097","https://openalex.org/W2042098439","https://openalex.org/W2046268109","https://openalex.org/W2048387155","https://openalex.org/W2059639161","https://openalex.org/W2078859253","https://openalex.org/W2094294257","https://openalex.org/W2094499330","https://openalex.org/W2097331836","https://openalex.org/W2101332957","https://openalex.org/W2102884976","https://openalex.org/W2112728443","https://openalex.org/W2119671639","https://openalex.org/W2119879917","https://openalex.org/W2129318972","https://openalex.org/W2133664160","https://openalex.org/W2159988464","https://openalex.org/W2161240017","https://openalex.org/W2171263166","https://openalex.org/W2325343629","https://openalex.org/W2432517183","https://openalex.org/W2465745915","https://openalex.org/W2970118546","https://openalex.org/W3016230452","https://openalex.org/W4253190278","https://openalex.org/W6683716363","https://openalex.org/W6766859361"],"related_works":["https://openalex.org/W2034520358","https://openalex.org/W2028099218","https://openalex.org/W2059639161","https://openalex.org/W1538056422","https://openalex.org/W2029084792","https://openalex.org/W2023738877","https://openalex.org/W2058895457","https://openalex.org/W2586325539","https://openalex.org/W2115857766","https://openalex.org/W2085560699"],"abstract_inverted_index":{"Multipass":[0],"dynamic":[1],"MRI":[2],"and":[3,17,36,84,107,117],"pharmacokinetic":[4],"modeling":[5],"are":[6,20,44,96,120],"used":[7],"to":[8,24,46,79],"estimate":[9,80],"perfusion":[10,27],"parameters":[11],"of":[12,100],"leaky":[13],"capillaries.":[14],"Curve":[15],"fitting":[16],"nonblind":[18,42,116],"deconvolution":[19,66],"the":[21,26,30,49,81,101],"established":[22],"methods":[23,43,119],"derive":[25],"estimates":[28],"from":[29,112],"observed":[31],"arterial":[32],"input":[33],"function":[34,78],"(AIF)":[35],"tissue":[37,75,85],"tracer":[38,76],"concentration":[39,77],"function.":[40,88],"These":[41],"sensitive":[45],"errors":[47,92],"in":[48,52],"AIF,":[50],"measured":[51],"some":[53],"nearby":[54],"artery":[55],"or":[56],"estimated":[57],"by":[58,105],"multichannel":[59,118],"blind":[60,65],"deconvolution.":[61],"Here,":[62],"a":[63,73],"single-channel":[64],"algorithm":[67,102],"is":[68,103],"presented,":[69],"which":[70],"only":[71],"uses":[72],"single":[74],"corresponding":[82,115],"AIF":[83],"impulse":[86],"response":[87],"That":[89],"way,":[90],"many":[91],"affecting":[93],"these":[94],"functions":[95],"reduced.":[97],"The":[98,114],"validity":[99],"supported":[104],"simulations":[106],"tests":[108],"on":[109],"real":[110],"data":[111],"mouse.":[113],"also":[121],"presented.":[122]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":6},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":1}],"updated_date":"2026-03-06T13:50:29.536080","created_date":"2025-10-10T00:00:00"}