{"id":"https://openalex.org/W2133291632","doi":"https://doi.org/10.1109/tbme.2010.2089984","title":"Control of Action Potential Duration Alternans in Canine Cardiac Ventricular Tissue","display_name":"Control of Action Potential Duration Alternans in Canine Cardiac Ventricular Tissue","publication_year":2010,"publication_date":"2010-11-09","ids":{"openalex":"https://openalex.org/W2133291632","doi":"https://doi.org/10.1109/tbme.2010.2089984","mag":"2133291632","pmid":"https://pubmed.ncbi.nlm.nih.gov/21041155"},"language":"en","primary_location":{"id":"doi:10.1109/tbme.2010.2089984","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tbme.2010.2089984","pdf_url":null,"source":{"id":"https://openalex.org/S5240358","display_name":"IEEE Transactions on Biomedical Engineering","issn_l":"0018-9294","issn":["0018-9294","1558-2531"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Biomedical Engineering","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3140543","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5064931531","display_name":"Uche B Kanu","orcid":null},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Uche B Kanu","raw_affiliation_strings":["Department of Biomedical Engineering, Cornell University, Ithaca, NY 14853, USA. ubk2@cornell.edu","Dept. of Biomed. Eng., Cornell Univ., Ithaca, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, Cornell University, Ithaca, NY 14853, USA. ubk2@cornell.edu","institution_ids":["https://openalex.org/I205783295"]},{"raw_affiliation_string":"Dept. of Biomed. Eng., Cornell Univ., Ithaca, NY, USA","institution_ids":["https://openalex.org/I205783295"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038294812","display_name":"Shahriar Iravanian","orcid":"https://orcid.org/0000-0003-2132-1543"},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shahriar Iravanian","raw_affiliation_strings":["Division of Cardiology, School of Medicine, Emory University, Atlanta, GA, USA","Sch. of Med., Div. of Cardiology, Emory Univ., Atlanta, GA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, School of Medicine, Emory University, Atlanta, GA, USA","institution_ids":["https://openalex.org/I150468666"]},{"raw_affiliation_string":"Sch. of Med., Div. of Cardiology, Emory Univ., Atlanta, GA, USA","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108564732","display_name":"Robert F. Gilmour","orcid":null},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert F Gilmour","raw_affiliation_strings":["Department of Biomedical Sciences, Cornell University, Ithaca, NY, USA","Dept. of Biomed. Eng., Cornell Univ., Ithaca, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Sciences, Cornell University, Ithaca, NY, USA","institution_ids":["https://openalex.org/I205783295"]},{"raw_affiliation_string":"Dept. of Biomed. Eng., Cornell Univ., Ithaca, NY, USA","institution_ids":["https://openalex.org/I205783295"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5035862691","display_name":"David J. Christini","orcid":"https://orcid.org/0000-0003-0852-2922"},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David J Christini","raw_affiliation_strings":["Greenberg Division of Cardiology and the Department of Physiology and Biophysics, Weill Medical College of Cornell University, New York, NY, USA","Dept. of Physiol. & Biophys., Weill Cornell Med. Coll., New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Greenberg Division of Cardiology and the Department of Physiology and Biophysics, Weill Medical College of Cornell University, New York, NY, USA","institution_ids":["https://openalex.org/I205783295"]},{"raw_affiliation_string":"Dept. of Physiol. & Biophys., Weill Cornell Med. Coll., New York, NY, USA","institution_ids":["https://openalex.org/I205783295"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":2645,"currency":"USD","value_usd":2645},"apc_paid":null,"fwci":0.5509,"has_fulltext":false,"cited_by_count":21,"citation_normalized_percentile":{"value":0.72410352,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"58","issue":"4","first_page":"894","last_page":"904"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10217","display_name":"Cardiac electrophysiology and arrhythmias","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10217","display_name":"Cardiac electrophysiology and arrhythmias","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11601","display_name":"Neuroscience and Neural Engineering","score":0.9965000152587891,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11217","display_name":"Cardiac Arrhythmias and Treatments","score":0.9952999949455261,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/optical-mapping","display_name":"Optical mapping","score":0.6392435431480408},{"id":"https://openalex.org/keywords/reentry","display_name":"Reentry","score":0.5974427461624146},{"id":"https://openalex.org/keywords/purkinje-fibers","display_name":"Purkinje fibers","score":0.5562180876731873},{"id":"https://openalex.org/keywords/cardiology","display_name":"Cardiology","score":0.5178199410438538},{"id":"https://openalex.org/keywords/ventricular-fibrillation","display_name":"Ventricular fibrillation","score":0.5108951926231384},{"id":"https://openalex.org/keywords/ventricular-action-potential","display_name":"Ventricular action potential","score":0.48542699217796326},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.45345234870910645},{"id":"https://openalex.org/keywords/beat","display_name":"Beat (acoustics)","score":0.4144800901412964},{"id":"https://openalex.org/keywords/biomedical-engineering","display_name":"Biomedical engineering","score":0.36430346965789795},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.32989054918289185},{"id":"https://openalex.org/keywords/electrophysiology","display_name":"Electrophysiology","score":0.2607858180999756},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.16559389233589172},{"id":"https://openalex.org/keywords/repolarization","display_name":"Repolarization","score":0.1490059792995453}],"concepts":[{"id":"https://openalex.org/C28289500","wikidata":"https://www.wikidata.org/wiki/Q7098868","display_name":"Optical mapping","level":2,"score":0.6392435431480408},{"id":"https://openalex.org/C2777720157","wikidata":"https://www.wikidata.org/wiki/Q7306947","display_name":"Reentry","level":2,"score":0.5974427461624146},{"id":"https://openalex.org/C2777463368","wikidata":"https://www.wikidata.org/wiki/Q2014587","display_name":"Purkinje fibers","level":3,"score":0.5562180876731873},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.5178199410438538},{"id":"https://openalex.org/C2781005686","wikidata":"https://www.wikidata.org/wiki/Q848662","display_name":"Ventricular fibrillation","level":2,"score":0.5108951926231384},{"id":"https://openalex.org/C47423411","wikidata":"https://www.wikidata.org/wiki/Q7920311","display_name":"Ventricular action potential","level":4,"score":0.48542699217796326},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.45345234870910645},{"id":"https://openalex.org/C189809214","wikidata":"https://www.wikidata.org/wiki/Q829522","display_name":"Beat (acoustics)","level":2,"score":0.4144800901412964},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.36430346965789795},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.32989054918289185},{"id":"https://openalex.org/C185263204","wikidata":"https://www.wikidata.org/wiki/Q1154774","display_name":"Electrophysiology","level":2,"score":0.2607858180999756},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.16559389233589172},{"id":"https://openalex.org/C146403970","wikidata":"https://www.wikidata.org/wiki/Q205729","display_name":"Repolarization","level":3,"score":0.1490059792995453},{"id":"https://openalex.org/C24890656","wikidata":"https://www.wikidata.org/wiki/Q82811","display_name":"Acoustics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000200","descriptor_name":"Action Potentials","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D000200","descriptor_name":"Action Potentials","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D000200","descriptor_name":"Action Potentials","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D000200","descriptor_name":"Action Potentials","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003936","descriptor_name":"Diagnosis, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D003936","descriptor_name":"Diagnosis, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D003936","descriptor_name":"Diagnosis, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D003936","descriptor_name":"Diagnosis, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D004285","descriptor_name":"Dogs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004285","descriptor_name":"Dogs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004285","descriptor_name":"Dogs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004285","descriptor_name":"Dogs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006329","descriptor_name":"Heart Conduction System","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006329","descriptor_name":"Heart Conduction System","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006329","descriptor_name":"Heart Conduction System","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006329","descriptor_name":"Heart Conduction System","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006339","descriptor_name":"Heart Rate","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006339","descriptor_name":"Heart Rate","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006339","descriptor_name":"Heart Rate","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006339","descriptor_name":"Heart Rate","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008955","descriptor_name":"Models, Cardiovascular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008955","descriptor_name":"Models, Cardiovascular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008955","descriptor_name":"Models, Cardiovascular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008955","descriptor_name":"Models, Cardiovascular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016277","descriptor_name":"Ventricular Function, Left","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D016277","descriptor_name":"Ventricular Function, Left","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D016277","descriptor_name":"Ventricular Function, Left","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D016277","descriptor_name":"Ventricular Function, Left","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D018780","descriptor_name":"Body Surface Potential Mapping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D018780","descriptor_name":"Body Surface Potential Mapping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D018780","descriptor_name":"Body Surface Potential Mapping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D018780","descriptor_name":"Body Surface Potential Mapping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D025461","descriptor_name":"Feedback, Physiological","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D025461","descriptor_name":"Feedback, Physiological","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D025461","descriptor_name":"Feedback, Physiological","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D025461","descriptor_name":"Feedback, Physiological","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1109/tbme.2010.2089984","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tbme.2010.2089984","pdf_url":null,"source":{"id":"https://openalex.org/S5240358","display_name":"IEEE Transactions on Biomedical Engineering","issn_l":"0018-9294","issn":["0018-9294","1558-2531"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Biomedical Engineering","raw_type":"journal-article"},{"id":"pmid:21041155","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21041155","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE transactions on bio-medical engineering","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:3140543","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3140543","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"IEEE Trans Biomed Eng","raw_type":"Text"},{"id":"pmh:oai:null:20.500.12648/15815","is_oa":false,"landing_page_url":"http://hdl.handle.net/20.500.12648/15815","pdf_url":null,"source":{"id":"https://openalex.org/S4306400078","display_name":"SUNY Digital Repository Support (State University of New York System)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I63190737","host_organization_name":"University at Buffalo, State University of New York","host_organization_lineage":["https://openalex.org/I63190737"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"904","raw_type":"Article/Review"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:3140543","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3140543","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"IEEE Trans Biomed Eng","raw_type":"Text"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1321878221","display_name":null,"funder_award_id":"F31 HL095267","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G3976246576","display_name":null,"funder_award_id":"R01-HL094620","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":50,"referenced_works":["https://openalex.org/W1489387013","https://openalex.org/W1876456565","https://openalex.org/W1973729956","https://openalex.org/W1976086141","https://openalex.org/W1982210904","https://openalex.org/W1982372873","https://openalex.org/W1984187338","https://openalex.org/W1991288228","https://openalex.org/W1994589684","https://openalex.org/W2004812098","https://openalex.org/W2013157031","https://openalex.org/W2013160285","https://openalex.org/W2017095658","https://openalex.org/W2022817095","https://openalex.org/W2023903233","https://openalex.org/W2028163040","https://openalex.org/W2029030701","https://openalex.org/W2039097153","https://openalex.org/W2040552151","https://openalex.org/W2045850425","https://openalex.org/W2055839156","https://openalex.org/W2056513081","https://openalex.org/W2061973954","https://openalex.org/W2065246793","https://openalex.org/W2065447334","https://openalex.org/W2077129671","https://openalex.org/W2088698297","https://openalex.org/W2094120668","https://openalex.org/W2096778977","https://openalex.org/W2102489746","https://openalex.org/W2106106159","https://openalex.org/W2112713043","https://openalex.org/W2112992757","https://openalex.org/W2115928923","https://openalex.org/W2127154973","https://openalex.org/W2135592885","https://openalex.org/W2146637030","https://openalex.org/W2146794919","https://openalex.org/W2147606003","https://openalex.org/W2162073557","https://openalex.org/W2162826334","https://openalex.org/W2165111060","https://openalex.org/W2334859129","https://openalex.org/W2411440828","https://openalex.org/W2425662256","https://openalex.org/W2442822067","https://openalex.org/W2605543710","https://openalex.org/W4251015067","https://openalex.org/W4254887950","https://openalex.org/W6714955399"],"related_works":["https://openalex.org/W2151785536","https://openalex.org/W2136474902","https://openalex.org/W1981404395","https://openalex.org/W2885743903","https://openalex.org/W2169998041","https://openalex.org/W639425854","https://openalex.org/W2100189903","https://openalex.org/W2114437999","https://openalex.org/W2158758233","https://openalex.org/W2076786320"],"abstract_inverted_index":{"Cardiac":[0],"electrical":[1],"alternans,":[2],"characterized":[3],"by":[4],"a":[5,13,39,55,63,180,187],"beat-to-beat":[6],"alternation":[7],"in":[8,71,100,122,156,198],"action":[9],"potential":[10],"waveform,":[11],"is":[12,38,107],"naturally":[14],"occurring":[15],"phenomenon,":[16],"which":[17,37],"can":[18],"occur":[19],"at":[20,62],"sufficiently":[21,72],"fast":[22],"pacing":[23],"rates.":[24],"Its":[25],"presence":[26],"has":[27],"been":[28,88],"putatively":[29],"linked":[30],"to":[31,41,90,172],"the":[32,81,101,114,142],"onset":[33],"of":[34,57,84,97,117,135,145,151,162,168,182,196],"cardiac":[35,74,199],"reentry,":[36],"precursor":[40],"ventricular":[42,105,127],"fibrillation.":[43],"Previous":[44],"studies":[45],"have":[46,87],"shown":[47],"that":[48,53],"closed-loop":[49],"alternans":[50,69,85,98,118,120,146,170,197],"control":[51,86,99,121,147,158,167,176,194],"techniques":[52],"apply":[54],"succession":[56],"externally":[58],"administered":[59],"cycle":[60],"perturbations":[61],"single":[64],"site":[65],"provide":[66,186],"limited":[67],"spatially-extended":[68,169],"elimination":[70],"large":[73],"substrates.":[75],"However,":[76],"detailed":[77],"experimental":[78],"investigations":[79,191],"into":[80,192],"spatial":[82,115,143,157],"dynamics":[83,116],"restricted":[89],"Purkinje":[91],"fiber":[92],"studies.":[93],"A":[94],"complete":[95],"understanding":[96],"more":[102],"clinically":[103],"relevant":[104],"tissue":[106],"needed.":[108],"In":[109],"this":[110],"paper,":[111],"we":[112,140],"study":[113],"and":[119],"arterially":[123],"perfused":[124],"canine":[125],"right":[126],"preparations":[128],"using":[129],"an":[130],"optical":[131],"mapping":[132],"system":[133],"capable":[134],"high-resolution":[136],"fluorescence":[137],"imaging.":[138],"Specifically,":[139],"quantify":[141],"efficacy":[144,177],"along":[148],"2.5":[149],"cm":[150],"tissue,":[152],"focusing":[153],"on":[154],"differences":[155],"between":[159],"different":[160],"subregions":[161],"tissue.":[163,200],"We":[164],"demonstrate":[165],"effective":[166],"up":[171],"2.0":[173],"cm,":[174],"with":[175],"attenuating":[178],"as":[179],"function":[181],"distance.":[183],"Our":[184],"results":[185],"basis":[188],"for":[189],"future":[190],"electrode-based":[193],"interventions":[195]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-08-26T07:47:46.906454","created_date":"2025-10-10T00:00:00"}