{"id":"https://openalex.org/W2161038017","doi":"https://doi.org/10.1109/tbme.2009.2031816","title":"Transcranial Ultrasonic Therapy Based on Time Reversal of Acoustically Induced Cavitation Bubble Signature","display_name":"Transcranial Ultrasonic Therapy Based on Time Reversal of Acoustically Induced Cavitation Bubble Signature","publication_year":2009,"publication_date":"2009-09-18","ids":{"openalex":"https://openalex.org/W2161038017","doi":"https://doi.org/10.1109/tbme.2009.2031816","mag":"2161038017","pmid":"https://pubmed.ncbi.nlm.nih.gov/19770084"},"language":"en","primary_location":{"id":"doi:10.1109/tbme.2009.2031816","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tbme.2009.2031816","pdf_url":null,"source":{"id":"https://openalex.org/S5240358","display_name":"IEEE Transactions on Biomedical Engineering","issn_l":"0018-9294","issn":["0018-9294","1558-2531"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Biomedical Engineering","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3081822","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5064616322","display_name":"J\u00e9r\u00f4me G\u00e2teau","orcid":"https://orcid.org/0000-0001-5230-8988"},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"funder","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210091942","display_name":"Institut Langevin","ror":"https://ror.org/00kr24y60","country_code":"FR","type":"facility","lineage":["https://openalex.org/I110736937","https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I154526488","https://openalex.org/I190752583","https://openalex.org/I204730241","https://openalex.org/I2746051580","https://openalex.org/I39804081","https://openalex.org/I4210091942","https://openalex.org/I98910050"]},{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"funder","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I204730241","display_name":"Universit\u00e9 Paris Cit\u00e9","ror":"https://ror.org/05f82e368","country_code":"FR","type":"education","lineage":["https://openalex.org/I204730241"]},{"id":"https://openalex.org/I98910050","display_name":"ESPCI Paris","ror":"https://ror.org/03zx86w41","country_code":"FR","type":"education","lineage":["https://openalex.org/I190752583","https://openalex.org/I2746051580","https://openalex.org/I98910050"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Jerome Gateau","raw_affiliation_strings":["Langevin Institute (CNRS UMR 7587), Inserm U979 Wave Physics for Medicine, Ecole Superieure de Physique et Chimie Industrielles de la Ville de Paris, Universit\u00e9 Paris VII, Paris, France. jerome.gateau@espci.fr","Langevin Inst., Univ. Paris VII, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Langevin Institute (CNRS UMR 7587), Inserm U979 Wave Physics for Medicine, Ecole Superieure de Physique et Chimie Industrielles de la Ville de Paris, Universit\u00e9 Paris VII, Paris, France. jerome.gateau@espci.fr","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I98910050","https://openalex.org/I1294671590"]},{"raw_affiliation_string":"Langevin Inst., Univ. Paris VII, Paris, France","institution_ids":["https://openalex.org/I4210091942","https://openalex.org/I204730241"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067689142","display_name":"Laurent Marsac","orcid":null},"institutions":[{"id":"https://openalex.org/I4210166534","display_name":"SuperSonic Imagine (France)","ror":"https://ror.org/05v2jtd22","country_code":"FR","type":"company","lineage":["https://openalex.org/I4210166534"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Laurent Marsac","raw_affiliation_strings":["Supersonic Imagine, Aix-en-Provence, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Supersonic Imagine, Aix-en-Provence, France","institution_ids":["https://openalex.org/I4210166534"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006303586","display_name":"Mathieu Pernot","orcid":"https://orcid.org/0000-0001-6713-4642"},"institutions":[{"id":"https://openalex.org/I4210091942","display_name":"Institut Langevin","ror":"https://ror.org/00kr24y60","country_code":"FR","type":"facility","lineage":["https://openalex.org/I110736937","https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I154526488","https://openalex.org/I190752583","https://openalex.org/I204730241","https://openalex.org/I2746051580","https://openalex.org/I39804081","https://openalex.org/I4210091942","https://openalex.org/I98910050"]},{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"funder","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"funder","lineage":["https://openalex.org/I154526488"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Mathieu Pernot","raw_affiliation_strings":["INSERM U979 \u201cWave Physics for Medicine\u201d, Langevin Institute (CNRS UMR 7587), Paris, France","INSERM U979 \"Wave Physics for Medicine\", Langevin Institute (CNRS UMR 7587), Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"INSERM U979 \u201cWave Physics for Medicine\u201d, Langevin Institute (CNRS UMR 7587), Paris, France","institution_ids":["https://openalex.org/I4210091942","https://openalex.org/I154526488","https://openalex.org/I1294671590"]},{"raw_affiliation_string":"INSERM U979 \"Wave Physics for Medicine\", Langevin Institute (CNRS UMR 7587), Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210091942","https://openalex.org/I1294671590"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047550032","display_name":"Jean\u2010Fran\u00e7ois Aubry","orcid":"https://orcid.org/0000-0003-2644-3945"},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"funder","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210091942","display_name":"Institut Langevin","ror":"https://ror.org/00kr24y60","country_code":"FR","type":"facility","lineage":["https://openalex.org/I110736937","https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I154526488","https://openalex.org/I190752583","https://openalex.org/I204730241","https://openalex.org/I2746051580","https://openalex.org/I39804081","https://openalex.org/I4210091942","https://openalex.org/I98910050"]},{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"funder","lineage":["https://openalex.org/I1294671590"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Jean-Francois Aubry","raw_affiliation_strings":["INSERM U979 \u201cWave Physics for Medicine\u201d, Langevin Institute (CNRS UMR 7587), Paris, France","INSERM U979 \"Wave Physics for Medicine\", Langevin Institute (CNRS UMR 7587), Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"INSERM U979 \u201cWave Physics for Medicine\u201d, Langevin Institute (CNRS UMR 7587), Paris, France","institution_ids":["https://openalex.org/I4210091942","https://openalex.org/I154526488","https://openalex.org/I1294671590"]},{"raw_affiliation_string":"INSERM U979 \"Wave Physics for Medicine\", Langevin Institute (CNRS UMR 7587), Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210091942","https://openalex.org/I1294671590"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5114377199","display_name":"Micka\u00ebl Tanter","orcid":"https://orcid.org/0000-0001-7739-8051"},"institutions":[{"id":"https://openalex.org/I4210091942","display_name":"Institut Langevin","ror":"https://ror.org/00kr24y60","country_code":"FR","type":"facility","lineage":["https://openalex.org/I110736937","https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I154526488","https://openalex.org/I190752583","https://openalex.org/I204730241","https://openalex.org/I2746051580","https://openalex.org/I39804081","https://openalex.org/I4210091942","https://openalex.org/I98910050"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"funder","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"funder","lineage":["https://openalex.org/I1294671590"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Mickael Tanter","raw_affiliation_strings":["INSERM U979 \u201cWave Physics for Medicine\u201d, Langevin Institute (CNRS UMR 7587), Paris, France","INSERM U979 \"Wave Physics for Medicine\", Langevin Institute (CNRS UMR 7587), Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"INSERM U979 \u201cWave Physics for Medicine\u201d, Langevin Institute (CNRS UMR 7587), Paris, France","institution_ids":["https://openalex.org/I4210091942","https://openalex.org/I154526488","https://openalex.org/I1294671590"]},{"raw_affiliation_string":"INSERM U979 \"Wave Physics for Medicine\", Langevin Institute (CNRS UMR 7587), Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210091942","https://openalex.org/I1294671590"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5076604032","display_name":"Mathias Fink","orcid":"https://orcid.org/0000-0002-8494-7562"},"institutions":[{"id":"https://openalex.org/I4210091942","display_name":"Institut Langevin","ror":"https://ror.org/00kr24y60","country_code":"FR","type":"facility","lineage":["https://openalex.org/I110736937","https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I154526488","https://openalex.org/I190752583","https://openalex.org/I204730241","https://openalex.org/I2746051580","https://openalex.org/I39804081","https://openalex.org/I4210091942","https://openalex.org/I98910050"]},{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"funder","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"funder","lineage":["https://openalex.org/I154526488"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Mathias Fink","raw_affiliation_strings":["INSERM U979 \u201cWave Physics for Medicine\u201d, Langevin Institute (CNRS UMR 7587), Paris, France","INSERM U979 \"Wave Physics for Medicine\", Langevin Institute (CNRS UMR 7587), Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"INSERM U979 \u201cWave Physics for Medicine\u201d, Langevin Institute (CNRS UMR 7587), Paris, France","institution_ids":["https://openalex.org/I4210091942","https://openalex.org/I154526488","https://openalex.org/I1294671590"]},{"raw_affiliation_string":"INSERM U979 \"Wave Physics for Medicine\", Langevin Institute (CNRS UMR 7587), Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210091942","https://openalex.org/I1294671590"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5064616322"],"corresponding_institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I4210091942","https://openalex.org/I98910050"],"apc_list":null,"apc_paid":null,"fwci":2.7548,"has_fulltext":false,"cited_by_count":89,"citation_normalized_percentile":{"value":0.90025113,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":94,"max":100},"biblio":{"volume":"57","issue":"1","first_page":"134","last_page":"144"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11739","display_name":"Microwave Imaging and Scattering Analysis","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11739","display_name":"Microwave Imaging and Scattering Analysis","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10958","display_name":"Ultrasound and Hyperthermia Applications","score":0.9991999864578247,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12015","display_name":"Photoacoustic and Ultrasonic Imaging","score":0.9983999729156494,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hydrophone","display_name":"Hydrophone","score":0.9038956165313721},{"id":"https://openalex.org/keywords/focus","display_name":"Focus (optics)","score":0.7721181511878967},{"id":"https://openalex.org/keywords/acoustics","display_name":"Acoustics","score":0.6622446179389954},{"id":"https://openalex.org/keywords/signal","display_name":"SIGNAL (programming language)","score":0.6264857649803162},{"id":"https://openalex.org/keywords/ultrasonic-sensor","display_name":"Ultrasonic sensor","score":0.604052722454071},{"id":"https://openalex.org/keywords/cavitation","display_name":"Cavitation","score":0.5675143599510193},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5036134123802185},{"id":"https://openalex.org/keywords/bubble","display_name":"Bubble","score":0.4824233949184418},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.22074639797210693},{"id":"https://openalex.org/keywords/optics","display_name":"Optics","score":0.21888962388038635}],"concepts":[{"id":"https://openalex.org/C2776328434","wikidata":"https://www.wikidata.org/wiki/Q798062","display_name":"Hydrophone","level":2,"score":0.9038956165313721},{"id":"https://openalex.org/C192209626","wikidata":"https://www.wikidata.org/wiki/Q190909","display_name":"Focus (optics)","level":2,"score":0.7721181511878967},{"id":"https://openalex.org/C24890656","wikidata":"https://www.wikidata.org/wiki/Q82811","display_name":"Acoustics","level":1,"score":0.6622446179389954},{"id":"https://openalex.org/C2779843651","wikidata":"https://www.wikidata.org/wiki/Q7390335","display_name":"SIGNAL (programming language)","level":2,"score":0.6264857649803162},{"id":"https://openalex.org/C81288441","wikidata":"https://www.wikidata.org/wiki/Q20736125","display_name":"Ultrasonic sensor","level":2,"score":0.604052722454071},{"id":"https://openalex.org/C207057113","wikidata":"https://www.wikidata.org/wiki/Q201666","display_name":"Cavitation","level":2,"score":0.5675143599510193},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5036134123802185},{"id":"https://openalex.org/C157915830","wikidata":"https://www.wikidata.org/wiki/Q2928001","display_name":"Bubble","level":2,"score":0.4824233949184418},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.22074639797210693},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.21888962388038635},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C173608175","wikidata":"https://www.wikidata.org/wiki/Q232661","display_name":"Parallel computing","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011312","descriptor_name":"Pressure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011312","descriptor_name":"Pressure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011312","descriptor_name":"Pressure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012815","descriptor_name":"Signal Processing, Computer-Assisted","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012815","descriptor_name":"Signal Processing, Computer-Assisted","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012815","descriptor_name":"Signal Processing, Computer-Assisted","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012886","descriptor_name":"Skull","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D012886","descriptor_name":"Skull","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D012886","descriptor_name":"Skull","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D013382","descriptor_name":"Subtraction Technique","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D013382","descriptor_name":"Subtraction Technique","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D013382","descriptor_name":"Subtraction Technique","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014464","descriptor_name":"Ultrasonic Therapy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D014464","descriptor_name":"Ultrasonic Therapy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D014464","descriptor_name":"Ultrasonic Therapy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D017585","descriptor_name":"Ultrasonography, Doppler, Transcranial","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D017585","descriptor_name":"Ultrasonography, Doppler, Transcranial","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D017585","descriptor_name":"Ultrasonography, Doppler, Transcranial","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019047","descriptor_name":"Phantoms, Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019047","descriptor_name":"Phantoms, Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019047","descriptor_name":"Phantoms, Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D045423","descriptor_name":"Microbubbles","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D045423","descriptor_name":"Microbubbles","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D045423","descriptor_name":"Microbubbles","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1109/tbme.2009.2031816","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tbme.2009.2031816","pdf_url":null,"source":{"id":"https://openalex.org/S5240358","display_name":"IEEE Transactions on Biomedical Engineering","issn_l":"0018-9294","issn":["0018-9294","1558-2531"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Biomedical Engineering","raw_type":"journal-article"},{"id":"pmid:19770084","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19770084","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE transactions on bio-medical engineering","raw_type":null},{"id":"pmh:oai:HAL:inserm-00547895v2","is_oa":false,"landing_page_url":"https://inserm.hal.science/inserm-00547895","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL (Le Centre pour la Communication Scientifique Directe)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1294671590","host_organization_name":"Centre National de la Recherche Scientifique","host_organization_lineage":["https://openalex.org/I1294671590"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"IEEE Transactions on Biomedical Engineering, 2010, 57 (1), pp.134-44. &#x27E8;10.1109/TBME.2009.2031816&#x27E9;","raw_type":"Journal articles"},{"id":"pmh:oai:pubmedcentral.nih.gov:3081822","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3081822","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"IEEE Trans Biomed Eng","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:3081822","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3081822","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"IEEE Trans Biomed Eng","raw_type":"Text"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":31,"referenced_works":["https://openalex.org/W37498885","https://openalex.org/W110384367","https://openalex.org/W1975462733","https://openalex.org/W1979872711","https://openalex.org/W2005527079","https://openalex.org/W2009819343","https://openalex.org/W2013031000","https://openalex.org/W2017741298","https://openalex.org/W2020951165","https://openalex.org/W2029373766","https://openalex.org/W2037839970","https://openalex.org/W2042425657","https://openalex.org/W2047918378","https://openalex.org/W2062287513","https://openalex.org/W2069168732","https://openalex.org/W2071890828","https://openalex.org/W2072224915","https://openalex.org/W2074029441","https://openalex.org/W2077224883","https://openalex.org/W2093245095","https://openalex.org/W2098027777","https://openalex.org/W2100648105","https://openalex.org/W2115852084","https://openalex.org/W2128508537","https://openalex.org/W2132398715","https://openalex.org/W2169057357","https://openalex.org/W2616402780","https://openalex.org/W4210949812","https://openalex.org/W4241673725","https://openalex.org/W4300025867","https://openalex.org/W6604484675"],"related_works":["https://openalex.org/W67232056","https://openalex.org/W4205230296","https://openalex.org/W1502076919","https://openalex.org/W1981489381","https://openalex.org/W2277106721","https://openalex.org/W199292434","https://openalex.org/W4319980365","https://openalex.org/W3139222168","https://openalex.org/W4372231798","https://openalex.org/W2070528179"],"abstract_inverted_index":{"Brain":[0],"treatment":[1],"through":[2,109,197],"the":[3,48,52,75,80,122,138,150,158,165,176,190,195,198],"skull":[4,53,114,199],"with":[5,12,64,84,167,182],"high-intensity":[6],"focused":[7],"ultrasound":[8],"can":[9],"be":[10,30,155],"achieved":[11],"multichannel":[13],"arrays":[14],"and":[15,70],"adaptive":[16],"focusing":[17,108],"techniques":[18],"such":[19],"as":[20,103],"time":[21,87],"reversal.":[22],"This":[23,59,140],"method":[24,62],"requires":[25],"a":[26,34,44,104,116,125],"reference":[27,151],"signal":[28,143],"to":[29,154,186],"either":[31],"emitted":[32,132],"by":[33,137],"real":[35],"source":[36,142],"embedded":[37],"in":[38,82],"brain":[39],"tissues":[40],"or":[41],"computed":[42,56],"from":[43,55,68,175],"virtual":[45],"source,":[46],"using":[47,89],"acoustic":[49,77],"properties":[50],"of":[51,124,149,194],"derived":[54],"tomography":[57],"images.":[58],"noninvasive":[60],"computational":[61],"focuses":[63],"precision,":[65],"but":[66],"suffers":[67],"modeling":[69],"repositioning":[71],"errors":[72],"that":[73,130],"reduce":[74],"accessible":[76],"pressure":[78,152,170],"at":[79,115,128,157],"focus":[81,129,166,178],"comparison":[83],"fully":[85],"experimental":[86],"reversal":[88],"an":[90,110,133,168],"implanted":[91],"hydrophone.":[92],"In":[93],"this":[94,96],"paper,":[95],"simulation-based":[97],"targeting":[98],"has":[99,120,144,179],"been":[100,180],"used":[101],"experimentally":[102],"first":[105],"step":[106],"for":[107],"ex":[111],"vivo":[112],"human":[113],"single":[117],"location.":[118],"It":[119],"enabled":[121],"creation":[123],"cavitation":[126],"bubble":[127,183,188],"spontaneously":[131],"ultrasonic":[134],"wave":[135],"received":[136],"array.":[139],"active":[141],"allowed":[145],"97":[146],"+/-":[147],"1.1%":[148],"(hydrophone-based)":[153],"restored":[156],"geometrical":[159],"focus.":[160],"To":[161],"target":[162],"points":[163],"around":[164],"optimal":[169],"level,":[171],"conventional":[172],"electronic":[173,191],"steering":[174,192],"initial":[177],"combined":[181],"generation.":[184],"Thanks":[185],"step-by-step":[187],"generation,":[189],"capabilities":[193],"array":[196],"were":[200],"improved.":[201]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":8},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":8},{"year":2022,"cited_by_count":6},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":12},{"year":2019,"cited_by_count":5},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":7},{"year":2014,"cited_by_count":5},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":2}],"updated_date":"2026-05-09T13:55:54.758798","created_date":"2025-10-10T00:00:00"}
