{"id":"https://openalex.org/W2120699325","doi":"https://doi.org/10.1109/tbme.2009.2027690","title":"A Tissue Framework for Simulating the Effects of Gastric Electrical Stimulation and<i>In Vivo</i>Validation","display_name":"A Tissue Framework for Simulating the Effects of Gastric Electrical Stimulation and<i>In Vivo</i>Validation","publication_year":2009,"publication_date":"2009-07-30","ids":{"openalex":"https://openalex.org/W2120699325","doi":"https://doi.org/10.1109/tbme.2009.2027690","mag":"2120699325","pmid":"https://pubmed.ncbi.nlm.nih.gov/19643697"},"language":"en","primary_location":{"id":"doi:10.1109/tbme.2009.2027690","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tbme.2009.2027690","pdf_url":null,"source":{"id":"https://openalex.org/S5240358","display_name":"IEEE Transactions on Biomedical Engineering","issn_l":"0018-9294","issn":["0018-9294","1558-2531"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Biomedical Engineering","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5031958340","display_name":"Peng Du","orcid":"https://orcid.org/0000-0002-6913-7545"},"institutions":[{"id":"https://openalex.org/I154130895","display_name":"University of Auckland","ror":"https://ror.org/03b94tp07","country_code":"NZ","type":"education","lineage":["https://openalex.org/I154130895"]},{"id":"https://openalex.org/I39854758","display_name":"Auckland University of Technology","ror":"https://ror.org/01zvqw119","country_code":"NZ","type":"education","lineage":["https://openalex.org/I39854758"]}],"countries":["NZ"],"is_corresponding":false,"raw_author_name":"Peng Du","raw_affiliation_strings":["Auckland Bioengineering Institute, The University of Auckland, Auckland 1142, New Zealand. peng.du@auckland.ac.nz","Auckland Bioeng. Inst., Univ. of Auckland, Auckland, New Zealand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Auckland Bioengineering Institute, The University of Auckland, Auckland 1142, New Zealand. peng.du@auckland.ac.nz","institution_ids":["https://openalex.org/I154130895","https://openalex.org/I39854758"]},{"raw_affiliation_string":"Auckland Bioeng. Inst., Univ. of Auckland, Auckland, New Zealand","institution_ids":["https://openalex.org/I154130895"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000581854","display_name":"Gregory O\u2019Grady","orcid":"https://orcid.org/0000-0002-5998-1080"},"institutions":[{"id":"https://openalex.org/I154130895","display_name":"University of Auckland","ror":"https://ror.org/03b94tp07","country_code":"NZ","type":"education","lineage":["https://openalex.org/I154130895"]}],"countries":["NZ"],"is_corresponding":false,"raw_author_name":"G. O'Grady","raw_affiliation_strings":["Auckland Bioengineering Institute and the Department of Surgery, The University of Auckland, Auckland, New Zealand","Dept. of Surg., Univ. of Auckland, Auckland, New Zealand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Auckland Bioengineering Institute and the Department of Surgery, The University of Auckland, Auckland, New Zealand","institution_ids":["https://openalex.org/I154130895"]},{"raw_affiliation_string":"Dept. of Surg., Univ. of Auckland, Auckland, New Zealand","institution_ids":["https://openalex.org/I154130895"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029294938","display_name":"John A. Windsor","orcid":"https://orcid.org/0000-0001-5995-5432"},"institutions":[{"id":"https://openalex.org/I154130895","display_name":"University of Auckland","ror":"https://ror.org/03b94tp07","country_code":"NZ","type":"education","lineage":["https://openalex.org/I154130895"]}],"countries":["NZ"],"is_corresponding":false,"raw_author_name":"J.A. Windsor","raw_affiliation_strings":["Department of Surgery, The University of Auckland, Auckland, New Zealand","Dept. of Surg., Univ. of Auckland, Auckland, New Zealand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, The University of Auckland, Auckland, New Zealand","institution_ids":["https://openalex.org/I154130895"]},{"raw_affiliation_string":"Dept. of Surg., Univ. of Auckland, Auckland, New Zealand","institution_ids":["https://openalex.org/I154130895"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036297582","display_name":"Leo K. Cheng","orcid":"https://orcid.org/0000-0003-2426-8987"},"institutions":[{"id":"https://openalex.org/I154130895","display_name":"University of Auckland","ror":"https://ror.org/03b94tp07","country_code":"NZ","type":"education","lineage":["https://openalex.org/I154130895"]}],"countries":["NZ"],"is_corresponding":false,"raw_author_name":"L.K. Cheng","raw_affiliation_strings":["Auckland Bioengineering Institute, The University of Auckland, Auckland, New Zealand","Auckland Bioeng. Inst., Univ. of Auckland, Auckland, New Zealand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Auckland Bioengineering Institute, The University of Auckland, Auckland, New Zealand","institution_ids":["https://openalex.org/I154130895"]},{"raw_affiliation_string":"Auckland Bioeng. Inst., Univ. of Auckland, Auckland, New Zealand","institution_ids":["https://openalex.org/I154130895"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5109150309","display_name":"Andrew J. Pullan","orcid":null},"institutions":[{"id":"https://openalex.org/I154130895","display_name":"University of Auckland","ror":"https://ror.org/03b94tp07","country_code":"NZ","type":"education","lineage":["https://openalex.org/I154130895"]}],"countries":["NZ"],"is_corresponding":false,"raw_author_name":"A.J. Pullan","raw_affiliation_strings":["Department of Engineering Science, The University of Auckland, Auckland, New Zealand","Department of Engineering Science,  University of Auckland, Auckland, New Zealand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Engineering Science, The University of Auckland, Auckland, New Zealand","institution_ids":["https://openalex.org/I154130895"]},{"raw_affiliation_string":"Department of Engineering Science,  University of Auckland, Auckland, New Zealand","institution_ids":["https://openalex.org/I154130895"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.0187,"has_fulltext":false,"cited_by_count":21,"citation_normalized_percentile":{"value":0.86022699,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"56","issue":"12","first_page":"2755","last_page":"2761"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10365","display_name":"Gastrointestinal motility and disorders","score":0.9824000000953674,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10365","display_name":"Gastrointestinal motility and disorders","score":0.9824000000953674,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/in-vivo","display_name":"In vivo","score":0.6468631029129028},{"id":"https://openalex.org/keywords/stimulation","display_name":"Stimulation","score":0.6330283880233765},{"id":"https://openalex.org/keywords/biomedical-engineering","display_name":"Biomedical engineering","score":0.5243721008300781},{"id":"https://openalex.org/keywords/biological-tissue","display_name":"Biological tissue","score":0.502051830291748},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.39377015829086304},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.34414011240005493},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.30793774127960205},{"id":"https://openalex.org/keywords/psychology","display_name":"Psychology","score":0.17299330234527588},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.1324956715106964}],"concepts":[{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.6468631029129028},{"id":"https://openalex.org/C24998067","wikidata":"https://www.wikidata.org/wiki/Q4114622","display_name":"Stimulation","level":2,"score":0.6330283880233765},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.5243721008300781},{"id":"https://openalex.org/C2983453321","wikidata":"https://www.wikidata.org/wiki/Q40397","display_name":"Biological tissue","level":2,"score":0.502051830291748},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.39377015829086304},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.34414011240005493},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.30793774127960205},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.17299330234527588},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1324956715106964},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004558","descriptor_name":"Electric Stimulation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D004558","descriptor_name":"Electric Stimulation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D004558","descriptor_name":"Electric Stimulation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D005769","descriptor_name":"Gastrointestinal Motility","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D005769","descriptor_name":"Gastrointestinal Motility","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D005769","descriptor_name":"Gastrointestinal Motility","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009119","descriptor_name":"Muscle Contraction","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009119","descriptor_name":"Muscle Contraction","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009119","descriptor_name":"Muscle Contraction","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009130","descriptor_name":"Muscle, Smooth","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009130","descriptor_name":"Muscle, Smooth","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009130","descriptor_name":"Muscle, Smooth","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D013270","descriptor_name":"Stomach","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D013270","descriptor_name":"Stomach","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D013270","descriptor_name":"Stomach","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D013552","descriptor_name":"Swine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013552","descriptor_name":"Swine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013552","descriptor_name":"Swine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1109/tbme.2009.2027690","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tbme.2009.2027690","pdf_url":null,"source":{"id":"https://openalex.org/S5240358","display_name":"IEEE Transactions on Biomedical Engineering","issn_l":"0018-9294","issn":["0018-9294","1558-2531"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Biomedical Engineering","raw_type":"journal-article"},{"id":"pmid:19643697","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19643697","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE transactions on bio-medical engineering","raw_type":null},{"id":"pmh:oai:europepmc.org:3138897","is_oa":false,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4169301","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9200000166893005,"display_name":"Affordable and clean energy","id":"https://metadata.un.org/sdg/7"}],"awards":[{"id":"https://openalex.org/G108104565","display_name":null,"funder_award_id":"R01 DK064775","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G6395752793","display_name":null,"funder_award_id":"R01 DK64775","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"}],"funders":[{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":38,"referenced_works":["https://openalex.org/W33315382","https://openalex.org/W81133468","https://openalex.org/W154426296","https://openalex.org/W592974461","https://openalex.org/W1595865504","https://openalex.org/W1967016258","https://openalex.org/W1968207847","https://openalex.org/W1975125476","https://openalex.org/W1983534047","https://openalex.org/W1988666276","https://openalex.org/W1990924290","https://openalex.org/W2008451599","https://openalex.org/W2017708435","https://openalex.org/W2025076095","https://openalex.org/W2031292702","https://openalex.org/W2031503773","https://openalex.org/W2036388052","https://openalex.org/W2049269388","https://openalex.org/W2058865554","https://openalex.org/W2060921140","https://openalex.org/W2067247169","https://openalex.org/W2072720373","https://openalex.org/W2098687414","https://openalex.org/W2102963388","https://openalex.org/W2104227995","https://openalex.org/W2113316793","https://openalex.org/W2119258055","https://openalex.org/W2124807360","https://openalex.org/W2146662882","https://openalex.org/W2164307342","https://openalex.org/W2279676782","https://openalex.org/W2285483946","https://openalex.org/W2413840425","https://openalex.org/W2616658159","https://openalex.org/W4239626309","https://openalex.org/W4240430385","https://openalex.org/W4254919817","https://openalex.org/W6696079740"],"related_works":["https://openalex.org/W2157355069","https://openalex.org/W2021792849","https://openalex.org/W1968701816","https://openalex.org/W2418264232","https://openalex.org/W2345263070","https://openalex.org/W303802408","https://openalex.org/W2350538445","https://openalex.org/W4390709402","https://openalex.org/W2017920131","https://openalex.org/W3191196319"],"abstract_inverted_index":{"Gastric":[0],"pacing":[1,53,69,178,193],"is":[2],"used":[3],"to":[4,43,86,140],"modulate":[5],"normal":[6],"or":[7],"abnormal":[8],"gastric":[9,81,174,192],"slow-wave":[10,48,82,110],"activity":[11,83],"for":[12,22,169,173,185],"therapeutic":[13],"purposes.":[14],"New":[15],"protocols":[16],"are":[17,20],"required":[18],"that":[19],"optimized":[21],"motility":[23],"outcomes":[24],"and":[25,37,100,108,119,125,149,162,165],"energy":[26],"efficiency.":[27],"A":[28],"computational":[29],"tissue":[30],"model":[31,67,153,181],"was":[32,58,84,138],"developed,":[33],"incorporating":[34],"smooth":[35],"muscle":[36],"interstitial":[38],"cell":[39],"of":[40,47,128,135,157,188],"Cajal":[41],"layers,":[42],"enable":[44],"predictive":[45,191],"simulations":[46,194],"entrainment":[49,62,129],"efficacy":[50],"under":[51],"different":[52],"frequencies.":[54],"Concurrent":[55],"experimental":[56,109],"validation":[57],"performed":[59],"via":[60],"high-resolution":[61],"mapping":[63],"in":[64,195],"a":[65,183],"porcine":[66],"(bipolar":[68],"protocol:":[70],"2":[71],"mA":[72],"amplitude;":[73],"400":[74],"ms":[75],"pulsewidth;":[76],"17-s":[77],"period;":[78],"midcorpus).":[79],"Entrained":[80],"found":[85,139],"be":[87,167],"anisotropic":[88],"(circular":[89],"direction:":[90],"8.51":[91],"mm":[92,97],"x":[93,98],"s(-1);":[94],"longitudinal:":[95],"4.58":[96],"s(-1)),":[99],"the":[101,143,147,155,186],"simulation":[102],"velocities":[103],"were":[104],"specified":[105],"accordingly.":[106],"Simulated":[107],"activities":[111],"demonstrated":[112],"satisfactory":[113],"agreement,":[114],"showing":[115],"similar":[116],"propagation":[117],"patterns":[118],"frequencies":[120,172],"(3.5-3.6":[121],"cycles":[122],"per":[123],"minute),":[124],"comparable":[126],"zones":[127],"(ZOEs;":[130],"64":[131],"cm(2)).":[132],"The":[133,180],"area":[134],"ZOE":[136],"achieved":[137],"depend":[141],"on":[142],"phase":[144,158],"interactions":[145,159],"between":[146,160],"native":[148,161],"entrained":[150,163],"activities.":[151],"This":[152],"allows":[154],"predictions":[156],"activities,":[164],"will":[166],"useful":[168],"determining":[170],"optimal":[171],"pacing,":[175],"including":[176],"multichannel":[177],"studies.":[179],"provides":[182],"framework":[184],"development":[187],"more":[189],"sophisticated":[190],"future.":[196]},"counts_by_year":[{"year":2021,"cited_by_count":2},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":4}],"updated_date":"2026-01-13T01:12:25.745995","created_date":"2016-06-24T00:00:00"}