{"id":"https://openalex.org/W4301391296","doi":"https://doi.org/10.1109/tbcas.2022.3211420","title":"A Scalable CMOS Molecular Electronics Chip for Single-Molecule Biosensing","display_name":"A Scalable CMOS Molecular Electronics Chip for Single-Molecule Biosensing","publication_year":2022,"publication_date":"2022-10-03","ids":{"openalex":"https://openalex.org/W4301391296","doi":"https://doi.org/10.1109/tbcas.2022.3211420","pmid":"https://pubmed.ncbi.nlm.nih.gov/36191107"},"language":"en","primary_location":{"id":"doi:10.1109/tbcas.2022.3211420","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tbcas.2022.3211420","pdf_url":null,"source":{"id":"https://openalex.org/S80299757","display_name":"IEEE Transactions on Biomedical Circuits and Systems","issn_l":"1932-4545","issn":["1932-4545","1940-9990"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Biomedical Circuits and Systems","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5040823901","display_name":"Drew A. Hall","orcid":"https://orcid.org/0000-0003-0674-074X"},"institutions":[{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Drew A. Hall","raw_affiliation_strings":["Department of Electrical and Computer Engineering, University of California, San Diego, CA, USA"],"affiliations":[{"raw_affiliation_string":"Department of Electrical and Computer Engineering, University of California, San Diego, CA, USA","institution_ids":["https://openalex.org/I36258959"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054497435","display_name":"Nagaraj Ananthapadmanabhan","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Nagaraj Ananthapadmanabhan","raw_affiliation_strings":["Roswell Biotechnologies, San Diego, CA, USA"],"affiliations":[{"raw_affiliation_string":"Roswell Biotechnologies, San Diego, CA, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101541349","display_name":"Chulmin Choi","orcid":"https://orcid.org/0000-0002-9805-5231"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Chulmin Choi","raw_affiliation_strings":["Roswell Biotechnologies, San Diego, CA, USA"],"affiliations":[{"raw_affiliation_string":"Roswell Biotechnologies, San Diego, CA, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112734567","display_name":"Le Zheng","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Le Zheng","raw_affiliation_strings":["Roswell Biotechnologies, San Diego, CA, USA"],"affiliations":[{"raw_affiliation_string":"Roswell Biotechnologies, San Diego, CA, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053476518","display_name":"Paul Pan","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Paul P. Pan","raw_affiliation_strings":["Roswell Biotechnologies, San Diego, CA, USA"],"affiliations":[{"raw_affiliation_string":"Roswell Biotechnologies, San Diego, CA, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007128828","display_name":"Christoph Von Jutrzenka","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Christoph Von Jutrzenka","raw_affiliation_strings":["Roswell Biotechnologies, San Diego, CA, USA"],"affiliations":[{"raw_affiliation_string":"Roswell Biotechnologies, San Diego, CA, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033940747","display_name":"Thuan Anh Nguyen","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Thuan Nguyen","raw_affiliation_strings":["Roswell Biotechnologies, San Diego, CA, USA"],"affiliations":[{"raw_affiliation_string":"Roswell Biotechnologies, San Diego, CA, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021613427","display_name":"Jose Rizo","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jose Rizo","raw_affiliation_strings":["Roswell Biotechnologies, San Diego, CA, USA"],"affiliations":[{"raw_affiliation_string":"Roswell Biotechnologies, San Diego, CA, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063653953","display_name":"Macklan Weinstein","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Macklan Weinstein","raw_affiliation_strings":["Roswell Biotechnologies, San Diego, CA, USA"],"affiliations":[{"raw_affiliation_string":"Roswell Biotechnologies, San Diego, CA, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020318232","display_name":"Raymond Lobaton","orcid":"https://orcid.org/0000-0002-7263-362X"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Raymond Lobaton","raw_affiliation_strings":["Roswell Biotechnologies, San Diego, CA, USA"],"affiliations":[{"raw_affiliation_string":"Roswell Biotechnologies, San Diego, CA, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072301529","display_name":"Prem Sinha","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Prem Sinha","raw_affiliation_strings":["Roswell Biotechnologies, San Diego, CA, USA"],"affiliations":[{"raw_affiliation_string":"Roswell Biotechnologies, San Diego, CA, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008062422","display_name":"Trevor Sauerbrey","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Trevor Sauerbrey","raw_affiliation_strings":["Roswell Biotechnologies, San Diego, CA, USA"],"affiliations":[{"raw_affiliation_string":"Roswell Biotechnologies, San Diego, CA, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032865936","display_name":"Cruz Sigala","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Cruz Sigala","raw_affiliation_strings":["Roswell Biotechnologies, San Diego, CA, USA"],"affiliations":[{"raw_affiliation_string":"Roswell Biotechnologies, San Diego, CA, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035747866","display_name":"Kathryne Bailey","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kathryne Bailey","raw_affiliation_strings":["Roswell Biotechnologies, San Diego, CA, USA"],"affiliations":[{"raw_affiliation_string":"Roswell Biotechnologies, San Diego, CA, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011433983","display_name":"Paul J. Mudondo","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Paul J. Mudondo","raw_affiliation_strings":["Roswell Biotechnologies, San Diego, CA, USA"],"affiliations":[{"raw_affiliation_string":"Roswell Biotechnologies, San Diego, CA, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103333558","display_name":"Ashesh Ray Chaudhuri","orcid":null},"institutions":[{"id":"https://openalex.org/I4210114974","display_name":"IMEC","ror":"https://ror.org/02kcbn207","country_code":"BE","type":"nonprofit","lineage":["https://openalex.org/I4210114974"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Ashesh Ray Chaudhuri","raw_affiliation_strings":["imec, Heverlee, Belgium"],"affiliations":[{"raw_affiliation_string":"imec, Heverlee, Belgium","institution_ids":["https://openalex.org/I4210114974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076176634","display_name":"Simone Severi","orcid":null},"institutions":[{"id":"https://openalex.org/I4210114974","display_name":"IMEC","ror":"https://ror.org/02kcbn207","country_code":"BE","type":"nonprofit","lineage":["https://openalex.org/I4210114974"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Simone Severi","raw_affiliation_strings":["imec, Heverlee, Belgium"],"affiliations":[{"raw_affiliation_string":"imec, Heverlee, Belgium","institution_ids":["https://openalex.org/I4210114974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062738930","display_name":"Carl W. Fuller","orcid":"https://orcid.org/0000-0003-2277-2119"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Carl W. Fuller","raw_affiliation_strings":["Roswell Biotechnologies, San Diego, CA, USA"],"affiliations":[{"raw_affiliation_string":"Roswell Biotechnologies, San Diego, CA, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056053028","display_name":"James M. Tour","orcid":"https://orcid.org/0000-0002-8479-9328"},"institutions":[{"id":"https://openalex.org/I74775410","display_name":"Rice University","ror":"https://ror.org/008zs3103","country_code":"US","type":"education","lineage":["https://openalex.org/I74775410"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James M. Tour","raw_affiliation_strings":["Rice University, Houston, TX, USA"],"affiliations":[{"raw_affiliation_string":"Rice University, Houston, TX, USA","institution_ids":["https://openalex.org/I74775410"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041718225","display_name":"Jin Sung-Ho","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sungho Jin","raw_affiliation_strings":["Roswell Biotechnologies, San Diego, CA, USA"],"affiliations":[{"raw_affiliation_string":"Roswell Biotechnologies, San Diego, CA, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039146903","display_name":"Paul W. Mola","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Paul W. Mola","raw_affiliation_strings":["Roswell Biotechnologies, San Diego, CA, USA"],"affiliations":[{"raw_affiliation_string":"Roswell Biotechnologies, San Diego, CA, USA","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5069489430","display_name":"Barry Merriman","orcid":"https://orcid.org/0000-0002-8042-3905"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Barry Merriman","raw_affiliation_strings":["Roswell Biotechnologies, San Diego, CA, USA"],"affiliations":[{"raw_affiliation_string":"Roswell Biotechnologies, San Diego, CA, USA","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":22,"corresponding_author_ids":["https://openalex.org/A5040823901"],"corresponding_institution_ids":["https://openalex.org/I36258959"],"apc_list":null,"apc_paid":null,"fwci":0.9204,"has_fulltext":false,"cited_by_count":10,"citation_normalized_percentile":{"value":0.73251413,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":98},"biblio":{"volume":"16","issue":"6","first_page":"1030","last_page":"1043"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10913","display_name":"Molecular Junctions and Nanostructures","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10913","display_name":"Molecular Junctions and Nanostructures","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11272","display_name":"Nanowire Synthesis and Applications","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11472","display_name":"Analytical Chemistry and Sensors","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/1502","display_name":"Bioengineering"},"field":{"id":"https://openalex.org/fields/15","display_name":"Chemical Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/biosensor","display_name":"Biosensor","score":0.8522913455963135},{"id":"https://openalex.org/keywords/millisecond","display_name":"Millisecond","score":0.7095404267311096},{"id":"https://openalex.org/keywords/cmos","display_name":"CMOS","score":0.6319577097892761},{"id":"https://openalex.org/keywords/chip","display_name":"Chip","score":0.5505035519599915},{"id":"https://openalex.org/keywords/molecular-electronics","display_name":"Molecular electronics","score":0.5402059555053711},{"id":"https://openalex.org/keywords/nanotechnology","display_name":"Nanotechnology","score":0.5190568566322327},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.47800981998443604},{"id":"https://openalex.org/keywords/molecular-biophysics","display_name":"Molecular biophysics","score":0.4500824809074402},{"id":"https://openalex.org/keywords/electronics","display_name":"Electronics","score":0.4167788028717041},{"id":"https://openalex.org/keywords/molecule","display_name":"Molecule","score":0.27050185203552246},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.2583165168762207},{"id":"https://openalex.org/keywords/optoelectronics","display_name":"Optoelectronics","score":0.2571951150894165},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.17066383361816406},{"id":"https://openalex.org/keywords/electrical-engineering","display_name":"Electrical engineering","score":0.1532835066318512},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.1389228105545044}],"concepts":[{"id":"https://openalex.org/C160756335","wikidata":"https://www.wikidata.org/wiki/Q669391","display_name":"Biosensor","level":2,"score":0.8522913455963135},{"id":"https://openalex.org/C60327585","wikidata":"https://www.wikidata.org/wiki/Q723733","display_name":"Millisecond","level":2,"score":0.7095404267311096},{"id":"https://openalex.org/C46362747","wikidata":"https://www.wikidata.org/wiki/Q173431","display_name":"CMOS","level":2,"score":0.6319577097892761},{"id":"https://openalex.org/C165005293","wikidata":"https://www.wikidata.org/wiki/Q1074500","display_name":"Chip","level":2,"score":0.5505035519599915},{"id":"https://openalex.org/C123057669","wikidata":"https://www.wikidata.org/wiki/Q899903","display_name":"Molecular electronics","level":3,"score":0.5402059555053711},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.5190568566322327},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.47800981998443604},{"id":"https://openalex.org/C70636015","wikidata":"https://www.wikidata.org/wiki/Q4300350","display_name":"Molecular biophysics","level":2,"score":0.4500824809074402},{"id":"https://openalex.org/C138331895","wikidata":"https://www.wikidata.org/wiki/Q11650","display_name":"Electronics","level":2,"score":0.4167788028717041},{"id":"https://openalex.org/C32909587","wikidata":"https://www.wikidata.org/wiki/Q11369","display_name":"Molecule","level":2,"score":0.27050185203552246},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.2583165168762207},{"id":"https://openalex.org/C49040817","wikidata":"https://www.wikidata.org/wiki/Q193091","display_name":"Optoelectronics","level":1,"score":0.2571951150894165},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.17066383361816406},{"id":"https://openalex.org/C119599485","wikidata":"https://www.wikidata.org/wiki/Q43035","display_name":"Electrical engineering","level":1,"score":0.1532835066318512},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.1389228105545044},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C1276947","wikidata":"https://www.wikidata.org/wiki/Q333","display_name":"Astronomy","level":1,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D004581","descriptor_name":"Electronics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004581","descriptor_name":"Electronics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004581","descriptor_name":"Electronics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012666","descriptor_name":"Semiconductors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012666","descriptor_name":"Semiconductors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012666","descriptor_name":"Semiconductors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015374","descriptor_name":"Biosensing Techniques","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D015374","descriptor_name":"Biosensing Techniques","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D015374","descriptor_name":"Biosensing Techniques","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D036103","descriptor_name":"Nanotechnology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D036103","descriptor_name":"Nanotechnology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D036103","descriptor_name":"Nanotechnology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1109/tbcas.2022.3211420","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tbcas.2022.3211420","pdf_url":null,"source":{"id":"https://openalex.org/S80299757","display_name":"IEEE Transactions on Biomedical Circuits and Systems","issn_l":"1932-4545","issn":["1932-4545","1940-9990"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Biomedical Circuits and Systems","raw_type":"journal-article"},{"id":"pmid:36191107","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/36191107","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE transactions on biomedical circuits and systems","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1538245367","display_name":null,"funder_award_id":"2019-19081900003","funder_id":"https://openalex.org/F4320333051","funder_display_name":"Intelligence Advanced Research Projects Activity"}],"funders":[{"id":"https://openalex.org/F4320312530","display_name":"Office of the Director of National Intelligence","ror":"https://ror.org/01v3fsc55"},{"id":"https://openalex.org/F4320333051","display_name":"Intelligence Advanced Research Projects Activity","ror":"https://ror.org/01v3fsc55"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":46,"referenced_works":["https://openalex.org/W135567997","https://openalex.org/W1819972003","https://openalex.org/W1986697603","https://openalex.org/W1993647765","https://openalex.org/W2018212627","https://openalex.org/W2020567521","https://openalex.org/W2021753230","https://openalex.org/W2025516544","https://openalex.org/W2045725637","https://openalex.org/W2069679617","https://openalex.org/W2077255563","https://openalex.org/W2080132578","https://openalex.org/W2093501926","https://openalex.org/W2098606699","https://openalex.org/W2115918673","https://openalex.org/W2147157132","https://openalex.org/W2156866094","https://openalex.org/W2168732909","https://openalex.org/W2259788764","https://openalex.org/W2279431357","https://openalex.org/W2288373993","https://openalex.org/W2468172085","https://openalex.org/W2565625374","https://openalex.org/W2605803411","https://openalex.org/W2801523643","https://openalex.org/W2802356701","https://openalex.org/W2802599954","https://openalex.org/W2965885602","https://openalex.org/W2982102943","https://openalex.org/W2997447852","https://openalex.org/W3000435127","https://openalex.org/W3011998402","https://openalex.org/W3017582230","https://openalex.org/W3026587057","https://openalex.org/W3031205627","https://openalex.org/W3120847607","https://openalex.org/W3126326356","https://openalex.org/W3181660183","https://openalex.org/W3210649219","https://openalex.org/W4206755506","https://openalex.org/W4206999951","https://openalex.org/W4213288431","https://openalex.org/W4220951341","https://openalex.org/W4226176503","https://openalex.org/W4240518122","https://openalex.org/W4254640185"],"related_works":["https://openalex.org/W4311282230","https://openalex.org/W2612718027","https://openalex.org/W2114556467","https://openalex.org/W1983117294","https://openalex.org/W1996127640","https://openalex.org/W2021065385","https://openalex.org/W2001003273","https://openalex.org/W4247660835","https://openalex.org/W1972815794","https://openalex.org/W4301391296"],"abstract_inverted_index":{"This":[0,155],"work":[1],"reports":[2],"the":[3,16,65,78,141,169],"first":[4],"CMOS":[5,112],"molecular":[6,79,105,156,164],"electronics":[7,157],"chip.":[8],"It":[9],"is":[10,20,86],"configured":[11],"as":[12,57],"a":[13,21,28,38,46,71,82,109,119,127,160],"biosensor,":[14],"where":[15],"primary":[17],"sensing":[18],"element":[19],"single":[22],"molecule":[23],"\"molecular":[24],"wire\"":[25],"consisting":[26],"of":[27,52,140,152,171],"\u223c100":[29],"G\u03a9,":[30],"25":[31],"nm":[32],"long":[33],"alpha-helical":[34],"peptide":[35,44],"integrated":[36],"into":[37],"current":[39,76,98],"monitoring":[40],"circuit.":[41],"The":[42,75,92,132],"engineered":[43],"contains":[45],"central":[47],"conjugation":[48],"site":[49],"for":[50,162],"attachment":[51],"various":[53],"probe":[54],"molecules,":[55],"such":[56,153],"DNA,":[58],"proteins,":[59],"enzymes,":[60],"or":[61],"antibodies,":[62],"which":[63],"program":[64],"biosensor":[66,134],"to":[67,167,174],"detect":[68],"interactions":[69],"with":[70,88,118],"specific":[72],"target":[73],"molecule.":[74],"through":[77],"wire":[80],"under":[81],"dc":[83],"applied":[84],"voltage":[85],"monitored":[87],"millisecond":[89],"temporal":[90],"resolution.":[91],"detected":[93],"signals":[94],"are":[95,116],"millisecond-scale,":[96],"picoampere":[97],"pulses":[99],"generated":[100],"by":[101],"each":[102],"transient":[103],"probe-target":[104],"interaction.":[106],"Implemented":[107],"in":[108,177],"0.18":[110],"\u03bcm":[111,121],"technology,":[113],"16k":[114],"sensors":[115],"arrayed":[117],"20":[120],"pitch":[122],"and":[123,185],"read":[124],"out":[125],"at":[126],"1":[128],"kHz":[129],"frame":[130],"rate.":[131],"resulting":[133],"chip":[135,158],"provides":[136,159],"direct,":[137],"real-time":[138],"observation":[139],"single-molecule":[142],"interaction":[143],"kinetics,":[144],"unlike":[145],"classical":[146],"biosensors":[147],"that":[148],"measure":[149],"ensemble":[150],"averages":[151],"events.":[154],"platform":[161],"putting":[163],"biosensing":[165],"\"on-chip\"":[166],"bring":[168],"power":[170],"semiconductor":[172],"chips":[173],"diverse":[175],"applications":[176],"biological":[178],"research,":[179],"diagnostics,":[180],"sequencing,":[181],"proteomics,":[182],"drug":[183],"discovery,":[184],"environmental":[186],"monitoring.":[187]},"counts_by_year":[{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":2}],"updated_date":"2026-03-27T05:58:40.876381","created_date":"2025-10-10T00:00:00"}