{"id":"https://openalex.org/W2760952345","doi":"https://doi.org/10.1109/tbcas.2017.2749451","title":"Equivalent Circuit of the Neuro-Electronic Junction for Signal Recordings From Planar and Engulfed Micro-Nano-Electrodes","display_name":"Equivalent Circuit of the Neuro-Electronic Junction for Signal Recordings From Planar and Engulfed Micro-Nano-Electrodes","publication_year":2017,"publication_date":"2017-10-05","ids":{"openalex":"https://openalex.org/W2760952345","doi":"https://doi.org/10.1109/tbcas.2017.2749451","mag":"2760952345","pmid":"https://pubmed.ncbi.nlm.nih.gov/28981426"},"language":"en","primary_location":{"id":"doi:10.1109/tbcas.2017.2749451","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tbcas.2017.2749451","pdf_url":null,"source":{"id":"https://openalex.org/S80299757","display_name":"IEEE Transactions on Biomedical Circuits and Systems","issn_l":"1932-4545","issn":["1932-4545","1940-9990"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Biomedical Circuits and Systems","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5031595657","display_name":"Giuseppe Massobrio","orcid":null},"institutions":[{"id":"https://openalex.org/I83816512","display_name":"University of Genoa","ror":"https://ror.org/0107c5v14","country_code":"IT","type":"education","lineage":["https://openalex.org/I83816512"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Giuseppe Massobrio","raw_affiliation_strings":["Department of Informatics, Bioengineering, Robotics and System Engineering, University of Genova, Genova, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Informatics, Bioengineering, Robotics and System Engineering, University of Genova, Genova, Italy","institution_ids":["https://openalex.org/I83816512"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046747801","display_name":"S\u00e9rgio Martinoia","orcid":"https://orcid.org/0000-0002-0058-9519"},"institutions":[{"id":"https://openalex.org/I4210137461","display_name":"Institute of Genetics and Biophysics","ror":"https://ror.org/04hadk112","country_code":"IT","type":"facility","lineage":["https://openalex.org/I4210137461","https://openalex.org/I4210155236"]},{"id":"https://openalex.org/I83816512","display_name":"University of Genoa","ror":"https://ror.org/0107c5v14","country_code":"IT","type":"education","lineage":["https://openalex.org/I83816512"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Sergio Martinoia","raw_affiliation_strings":["Department of Informatics, Bioengineering, Robotics and System Engineering, University of Genova, Genova, Italy","Institute of Biophysics, CNR, Genova, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Informatics, Bioengineering, Robotics and System Engineering, University of Genova, Genova, Italy","institution_ids":["https://openalex.org/I83816512"]},{"raw_affiliation_string":"Institute of Biophysics, CNR, Genova, Italy","institution_ids":["https://openalex.org/I4210137461"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5024860745","display_name":"Paolo Massobrio","orcid":"https://orcid.org/0000-0001-8335-3407"},"institutions":[{"id":"https://openalex.org/I83816512","display_name":"University of Genoa","ror":"https://ror.org/0107c5v14","country_code":"IT","type":"education","lineage":["https://openalex.org/I83816512"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Paolo Massobrio","raw_affiliation_strings":["Department of Informatics, Bioengineering, Robotics and System Engineering, University of Genova, Genova, Italy"],"raw_orcid":"https://orcid.org/0000-0001-8335-3407","affiliations":[{"raw_affiliation_string":"Department of Informatics, Bioengineering, Robotics and System Engineering, University of Genova, Genova, Italy","institution_ids":["https://openalex.org/I83816512"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5031595657"],"corresponding_institution_ids":["https://openalex.org/I83816512"],"apc_list":null,"apc_paid":null,"fwci":1.1983,"has_fulltext":false,"cited_by_count":29,"citation_normalized_percentile":{"value":0.75376704,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":99},"biblio":{"volume":"12","issue":"1","first_page":"3","last_page":"12"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11601","display_name":"Neuroscience and Neural Engineering","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11601","display_name":"Neuroscience and Neural Engineering","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11434","display_name":"Electrochemical Analysis and Applications","score":0.9980999827384949,"subfield":{"id":"https://openalex.org/subfields/1603","display_name":"Electrochemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11472","display_name":"Analytical Chemistry and Sensors","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/1502","display_name":"Bioengineering"},"field":{"id":"https://openalex.org/fields/15","display_name":"Chemical Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/microelectrode","display_name":"Microelectrode","score":0.9639568328857422},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.621529221534729},{"id":"https://openalex.org/keywords/signal","display_name":"SIGNAL (programming language)","score":0.5897040963172913},{"id":"https://openalex.org/keywords/multielectrode-array","display_name":"Multielectrode array","score":0.5809869170188904},{"id":"https://openalex.org/keywords/electrode","display_name":"Electrode","score":0.5778952836990356},{"id":"https://openalex.org/keywords/planar","display_name":"Planar","score":0.5236268639564514},{"id":"https://openalex.org/keywords/coupling","display_name":"Coupling (piping)","score":0.46326616406440735},{"id":"https://openalex.org/keywords/electrophysiology","display_name":"Electrophysiology","score":0.44829511642456055},{"id":"https://openalex.org/keywords/optoelectronics","display_name":"Optoelectronics","score":0.35988444089889526},{"id":"https://openalex.org/keywords/nanotechnology","display_name":"Nanotechnology","score":0.3200593590736389},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.22680318355560303},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.17443910241127014},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.13784748315811157}],"concepts":[{"id":"https://openalex.org/C111670793","wikidata":"https://www.wikidata.org/wiki/Q16979465","display_name":"Microelectrode","level":3,"score":0.9639568328857422},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.621529221534729},{"id":"https://openalex.org/C2779843651","wikidata":"https://www.wikidata.org/wiki/Q7390335","display_name":"SIGNAL (programming language)","level":2,"score":0.5897040963172913},{"id":"https://openalex.org/C95967509","wikidata":"https://www.wikidata.org/wiki/Q1952355","display_name":"Multielectrode array","level":4,"score":0.5809869170188904},{"id":"https://openalex.org/C17525397","wikidata":"https://www.wikidata.org/wiki/Q176140","display_name":"Electrode","level":2,"score":0.5778952836990356},{"id":"https://openalex.org/C134786449","wikidata":"https://www.wikidata.org/wiki/Q3391255","display_name":"Planar","level":2,"score":0.5236268639564514},{"id":"https://openalex.org/C131584629","wikidata":"https://www.wikidata.org/wiki/Q4308705","display_name":"Coupling (piping)","level":2,"score":0.46326616406440735},{"id":"https://openalex.org/C185263204","wikidata":"https://www.wikidata.org/wiki/Q1154774","display_name":"Electrophysiology","level":2,"score":0.44829511642456055},{"id":"https://openalex.org/C49040817","wikidata":"https://www.wikidata.org/wiki/Q193091","display_name":"Optoelectronics","level":1,"score":0.35988444089889526},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.3200593590736389},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.22680318355560303},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.17443910241127014},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.13784748315811157},{"id":"https://openalex.org/C147789679","wikidata":"https://www.wikidata.org/wiki/Q11372","display_name":"Physical chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C121684516","wikidata":"https://www.wikidata.org/wiki/Q7600677","display_name":"Computer graphics (images)","level":1,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C191897082","wikidata":"https://www.wikidata.org/wiki/Q11467","display_name":"Metallurgy","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008839","descriptor_name":"Microelectrodes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008839","descriptor_name":"Microelectrodes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008839","descriptor_name":"Microelectrodes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008959","descriptor_name":"Models, Neurological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008959","descriptor_name":"Models, Neurological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008959","descriptor_name":"Models, Neurological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009435","descriptor_name":"Synaptic Transmission","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009435","descriptor_name":"Synaptic Transmission","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009435","descriptor_name":"Synaptic Transmission","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D049329","descriptor_name":"Nanostructures","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D049329","descriptor_name":"Nanostructures","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D049329","descriptor_name":"Nanostructures","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1109/tbcas.2017.2749451","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tbcas.2017.2749451","pdf_url":null,"source":{"id":"https://openalex.org/S80299757","display_name":"IEEE Transactions on Biomedical Circuits and Systems","issn_l":"1932-4545","issn":["1932-4545","1940-9990"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Biomedical Circuits and Systems","raw_type":"journal-article"},{"id":"pmid:28981426","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28981426","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE transactions on biomedical circuits and systems","raw_type":null},{"id":"pmh:oai:iris.unige.it:11567/884213","is_oa":false,"landing_page_url":"http://hdl.handle.net/11567/884213","pdf_url":null,"source":{"id":"https://openalex.org/S4377196291","display_name":"CINECA IRIS Institutial Research Information System (University of Genoa)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I83816512","host_organization_name":"University of Genoa","host_organization_lineage":["https://openalex.org/I83816512"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":45,"referenced_works":["https://openalex.org/W761312605","https://openalex.org/W1532219419","https://openalex.org/W1581056687","https://openalex.org/W1596990491","https://openalex.org/W1640629060","https://openalex.org/W1944942801","https://openalex.org/W1964380577","https://openalex.org/W1968952650","https://openalex.org/W1979694263","https://openalex.org/W1982448820","https://openalex.org/W1985940938","https://openalex.org/W1986041092","https://openalex.org/W1999743880","https://openalex.org/W2000884802","https://openalex.org/W2004526523","https://openalex.org/W2015534243","https://openalex.org/W2018307732","https://openalex.org/W2022690372","https://openalex.org/W2025288428","https://openalex.org/W2031375160","https://openalex.org/W2034433608","https://openalex.org/W2044207434","https://openalex.org/W2055758313","https://openalex.org/W2064379826","https://openalex.org/W2069594522","https://openalex.org/W2077164262","https://openalex.org/W2078624039","https://openalex.org/W2083250197","https://openalex.org/W2086174087","https://openalex.org/W2100507049","https://openalex.org/W2126012359","https://openalex.org/W2126203685","https://openalex.org/W2128625609","https://openalex.org/W2138968835","https://openalex.org/W2141111805","https://openalex.org/W2156934669","https://openalex.org/W2335294513","https://openalex.org/W2408479404","https://openalex.org/W2465718101","https://openalex.org/W2605023718","https://openalex.org/W2949596620","https://openalex.org/W4211066815","https://openalex.org/W4250543537","https://openalex.org/W6622325470","https://openalex.org/W6634613481"],"related_works":["https://openalex.org/W2061877343","https://openalex.org/W2028205923","https://openalex.org/W2381760774","https://openalex.org/W2037345099","https://openalex.org/W2964977587","https://openalex.org/W2768056422","https://openalex.org/W2417316355","https://openalex.org/W2103878090","https://openalex.org/W2047718741","https://openalex.org/W2183329029"],"abstract_inverted_index":{"In":[0,20,54],"the":[1,29,35,38,64,83,119,127,146,154],"latest":[2],"years,":[3],"several":[4],"attempts":[5],"to":[6,10,27,50,68,145],"develop":[7],"extracellular":[8],"microtransducers":[9],"record":[11],"electrophysiological":[12,149],"activity":[13,107],"of":[14,37,48,63,82,118],"excitable":[15],"cells":[16],"have":[17,24],"been":[18,25],"done.":[19],"particular,":[21],"many":[22],"efforts":[23],"oriented":[26],"increase":[28],"coupling":[30],"conditions,":[31],"and,":[32],"thus,":[33],"improving":[34],"quality":[36],"recorded":[39,148],"signal.":[40],"Gold":[41],"mushroom-shaped":[42],"microelectrodes":[43],"(GM\u03bcE)":[44],"are":[45,102,143],"an":[46,59],"example":[47],"nano-devices":[49],"achieve":[51],"those":[52],"requirements.":[53],"this":[55,79],"study,":[56],"we":[57],"developed":[58],"equivalent":[60],"electrical":[61,106],"circuit":[62],"neuron-microelectrode":[65,128],"system":[66],"interface":[67],"simulate":[69],"signal":[70],"recordings":[71],"from":[72],"both":[73],"planar":[74,87],"and":[75,89,97,113,132,139],"engulfed":[76],"micro-nano-electrodes.":[77],"To":[78],"purpose,":[80],"models":[81,123],"neuron,":[84],"planar,":[85],"gold":[86],"microelectrode,":[88],"GM\u03bcE,":[90],"neuro-electronic":[91],"junction":[92],"(microelectrode-electrolyte":[93],"interface,":[94],"cleft":[95,129],"effect,":[96],"protein-glycocalyx":[98],"electric":[99],"double":[100],"layer)":[101],"presented.":[103],"Then,":[104],"neuronal":[105,150],"is":[108],"simulated":[109],"by":[110],"Hspice":[111],"software,":[112],"analyzed":[114],"as":[115,126],"a":[116],"function":[117],"most":[120],"sensitive":[121],"biophysical":[122],"parameters,":[124],"such":[125],"width,":[130],"spreading":[131],"seal":[133],"resistances,":[134],"ion-channel":[135],"densities,":[136],"double-layer":[137],"properties,":[138],"microelectrode":[140],"geometries.":[141],"Results":[142],"referenced":[144],"experimentally":[147],"signals":[151],"reported":[152],"in":[153],"literature.":[155]},"counts_by_year":[{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":7},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":3}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}