{"id":"https://openalex.org/W2150566250","doi":"https://doi.org/10.1109/tbcas.2009.2021657","title":"Microfluidic System for Controlled Gelation of a Thermally Reversible Hydrogel","display_name":"Microfluidic System for Controlled Gelation of a Thermally Reversible Hydrogel","publication_year":2009,"publication_date":"2009-07-15","ids":{"openalex":"https://openalex.org/W2150566250","doi":"https://doi.org/10.1109/tbcas.2009.2021657","mag":"2150566250","pmid":"https://pubmed.ncbi.nlm.nih.gov/23853240"},"language":"en","primary_location":{"id":"doi:10.1109/tbcas.2009.2021657","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tbcas.2009.2021657","pdf_url":null,"source":{"id":"https://openalex.org/S80299757","display_name":"IEEE Transactions on Biomedical Circuits and Systems","issn_l":"1932-4545","issn":["1932-4545","1940-9990"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Biomedical Circuits and Systems","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5025317500","display_name":"Jonas Flueckiger","orcid":null},"institutions":[{"id":"https://openalex.org/I141945490","display_name":"University of British Columbia","ror":"https://ror.org/03rmrcq20","country_code":"CA","type":"education","lineage":["https://openalex.org/I141945490"]}],"countries":["CA"],"is_corresponding":true,"raw_author_name":"Jonas Flueckiger","raw_affiliation_strings":["Department of Electrical and Computer Engineering, University of British Columbia, Vancouver, BC, Canada"],"affiliations":[{"raw_affiliation_string":"Department of Electrical and Computer Engineering, University of British Columbia, Vancouver, BC, Canada","institution_ids":["https://openalex.org/I141945490"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5072718301","display_name":"Karen C. Cheung","orcid":"https://orcid.org/0000-0001-9522-3351"},"institutions":[{"id":"https://openalex.org/I141945490","display_name":"University of British Columbia","ror":"https://ror.org/03rmrcq20","country_code":"CA","type":"education","lineage":["https://openalex.org/I141945490"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Karen C. Cheung","raw_affiliation_strings":["Department of Electrical and Computer Engineering, University of British Columbia, Vancouver, BC, Canada"],"affiliations":[{"raw_affiliation_string":"Department of Electrical and Computer Engineering, University of British Columbia, Vancouver, BC, Canada","institution_ids":["https://openalex.org/I141945490"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5025317500"],"corresponding_institution_ids":["https://openalex.org/I141945490"],"apc_list":null,"apc_paid":null,"fwci":0.4447,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.68764337,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"3","issue":"4","first_page":"195","last_page":"201"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11407","display_name":"Innovative Microfluidic and Catalytic Techniques Innovation","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11407","display_name":"Innovative Microfluidic and Catalytic Techniques Innovation","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11190","display_name":"3D Printing in Biomedical Research","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10412","display_name":"Microfluidic and Capillary Electrophoresis Applications","score":0.9962999820709229,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/microfluidics","display_name":"Microfluidics","score":0.853340208530426},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.6621624827384949},{"id":"https://openalex.org/keywords/nanotechnology","display_name":"Nanotechnology","score":0.5701871514320374},{"id":"https://openalex.org/keywords/shearing","display_name":"Shearing (physics)","score":0.5512979626655579},{"id":"https://openalex.org/keywords/tissue-engineering","display_name":"Tissue engineering","score":0.5499184727668762},{"id":"https://openalex.org/keywords/chemical-engineering","display_name":"Chemical engineering","score":0.37351134419441223},{"id":"https://openalex.org/keywords/biomedical-engineering","display_name":"Biomedical engineering","score":0.17020970582962036},{"id":"https://openalex.org/keywords/composite-material","display_name":"Composite material","score":0.15380829572677612}],"concepts":[{"id":"https://openalex.org/C8673954","wikidata":"https://www.wikidata.org/wiki/Q138845","display_name":"Microfluidics","level":2,"score":0.853340208530426},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.6621624827384949},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.5701871514320374},{"id":"https://openalex.org/C152279782","wikidata":"https://www.wikidata.org/wiki/Q13583542","display_name":"Shearing (physics)","level":2,"score":0.5512979626655579},{"id":"https://openalex.org/C49892992","wikidata":"https://www.wikidata.org/wiki/Q1540285","display_name":"Tissue engineering","level":2,"score":0.5499184727668762},{"id":"https://openalex.org/C42360764","wikidata":"https://www.wikidata.org/wiki/Q83588","display_name":"Chemical engineering","level":1,"score":0.37351134419441223},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.17020970582962036},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.15380829572677612},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1109/tbcas.2009.2021657","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tbcas.2009.2021657","pdf_url":null,"source":{"id":"https://openalex.org/S80299757","display_name":"IEEE Transactions on Biomedical Circuits and Systems","issn_l":"1932-4545","issn":["1932-4545","1940-9990"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Biomedical Circuits and Systems","raw_type":"journal-article"},{"id":"pmid:23853240","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23853240","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE transactions on biomedical circuits and systems","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/6","display_name":"Clean water and sanitation","score":0.5}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":24,"referenced_works":["https://openalex.org/W1964346108","https://openalex.org/W1966590541","https://openalex.org/W1971141424","https://openalex.org/W1975833234","https://openalex.org/W1981471402","https://openalex.org/W1988833663","https://openalex.org/W2009434334","https://openalex.org/W2026699828","https://openalex.org/W2033870293","https://openalex.org/W2037301800","https://openalex.org/W2049072600","https://openalex.org/W2061655358","https://openalex.org/W2064993291","https://openalex.org/W2068547526","https://openalex.org/W2079531617","https://openalex.org/W2087150084","https://openalex.org/W2097285994","https://openalex.org/W2125224774","https://openalex.org/W2125376475","https://openalex.org/W2137034111","https://openalex.org/W2148867518","https://openalex.org/W2160322193","https://openalex.org/W4210960748","https://openalex.org/W4240881095"],"related_works":["https://openalex.org/W2748952813","https://openalex.org/W3103016203","https://openalex.org/W2106238498","https://openalex.org/W2463681241","https://openalex.org/W97203997","https://openalex.org/W2998489467","https://openalex.org/W1998250559","https://openalex.org/W4223581013","https://openalex.org/W4210313937","https://openalex.org/W2141338322"],"abstract_inverted_index":{"The":[0,74],"integration":[1],"of":[2,36,60,65,76],"cell":[3,27,88],"culture":[4],"and":[5,22,42,90],"characterization":[6],"onto":[7],"a":[8,37],"miniaturized":[9],"platform":[10],"promises":[11],"to":[12],"benefit":[13],"many":[14],"applications":[15],"such":[16],"as":[17],"tissue":[18],"engineering,":[19],"drug":[20],"screening,":[21],"those":[23],"involving":[24],"small,":[25],"precious":[26],"populations.":[28],"This":[29],"paper":[30],"presents":[31],"the":[32,84],"controlled":[33],"on-chip":[34,72],"gelation":[35],"thermally-reversible":[38],"hydrogel.":[39],"Channel":[40],"design":[41],"flowrate":[43],"control":[44,54],"are":[45],"crucial":[46],"in":[47],"determining":[48],"hydrogel":[49,61],"geometry,":[50],"while":[51],"integrated":[52],"temperature":[53,75],"triggers":[55],"reversible":[56],"gel":[57],"formation.":[58],"Formation":[59],"droplets":[62],"through":[63],"shearing":[64],"immiscible":[66],"flows":[67],"is":[68],"demonstrated":[69],"with":[70],"subsequent":[71],"gelation.":[73],"phase":[77],"transition":[78],"occurs":[79],"between":[80],"32degC-34degC,":[81],"well":[82],"within":[83],"range":[85],"for":[86],"mammalian":[87],"encapsulation":[89],"culture.":[91]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}
