{"id":"https://openalex.org/W3023573174","doi":"https://doi.org/10.1109/tase.2020.2989760","title":"Robotic Batch Somatic Cell Nuclear Transfer Based on Microfluidic Groove","display_name":"Robotic Batch Somatic Cell Nuclear Transfer Based on Microfluidic Groove","publication_year":2020,"publication_date":"2020-05-06","ids":{"openalex":"https://openalex.org/W3023573174","doi":"https://doi.org/10.1109/tase.2020.2989760","mag":"3023573174"},"language":"en","primary_location":{"id":"doi:10.1109/tase.2020.2989760","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tase.2020.2989760","pdf_url":null,"source":{"id":"https://openalex.org/S34881539","display_name":"IEEE Transactions on Automation Science and Engineering","issn_l":"1545-5955","issn":["1545-5955","1558-3783"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Automation Science and Engineering","raw_type":"journal-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5082505158","display_name":"Yaowei Liu","orcid":"https://orcid.org/0000-0002-4674-676X"},"institutions":[{"id":"https://openalex.org/I205237279","display_name":"Nankai University","ror":"https://ror.org/01y1kjr75","country_code":"CN","type":"education","lineage":["https://openalex.org/I205237279"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yaowei Liu","raw_affiliation_strings":["Institute of Robotics and Automatic Information System (IRAIS), Nankai University, Tianjin, China","Tianjin Key Laboratory of Intelligent Robotic (tjKLIR), Nankai University, Tianjin, China"],"raw_orcid":"https://orcid.org/0000-0002-4674-676X","affiliations":[{"raw_affiliation_string":"Institute of Robotics and Automatic Information System (IRAIS), Nankai University, Tianjin, China","institution_ids":["https://openalex.org/I205237279"]},{"raw_affiliation_string":"Tianjin Key Laboratory of Intelligent Robotic (tjKLIR), Nankai University, Tianjin, China","institution_ids":["https://openalex.org/I205237279"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100451952","display_name":"Xuefeng Wang","orcid":"https://orcid.org/0000-0002-3301-3196"},"institutions":[{"id":"https://openalex.org/I205237279","display_name":"Nankai University","ror":"https://ror.org/01y1kjr75","country_code":"CN","type":"education","lineage":["https://openalex.org/I205237279"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xuefeng Wang","raw_affiliation_strings":["Institute of Robotics and Automatic Information System (IRAIS), Nankai University, Tianjin, China","Tianjin Key Laboratory of Intelligent Robotic (tjKLIR), Nankai University, Tianjin, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Robotics and Automatic Information System (IRAIS), Nankai University, Tianjin, China","institution_ids":["https://openalex.org/I205237279"]},{"raw_affiliation_string":"Tianjin Key Laboratory of Intelligent Robotic (tjKLIR), Nankai University, Tianjin, China","institution_ids":["https://openalex.org/I205237279"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090578099","display_name":"Qili Zhao","orcid":"https://orcid.org/0000-0002-9517-7460"},"institutions":[{"id":"https://openalex.org/I205237279","display_name":"Nankai University","ror":"https://ror.org/01y1kjr75","country_code":"CN","type":"education","lineage":["https://openalex.org/I205237279"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qili Zhao","raw_affiliation_strings":["Institute of Robotics and Automatic Information System (IRAIS), Nankai University, Tianjin, China","Tianjin Key Laboratory of Intelligent Robotic (tjKLIR), Nankai University, Tianjin, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Robotics and Automatic Information System (IRAIS), Nankai University, Tianjin, China","institution_ids":["https://openalex.org/I205237279"]},{"raw_affiliation_string":"Tianjin Key Laboratory of Intelligent Robotic (tjKLIR), Nankai University, Tianjin, China","institution_ids":["https://openalex.org/I205237279"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034713347","display_name":"Xin Zhao","orcid":"https://orcid.org/0000-0003-0631-4628"},"institutions":[{"id":"https://openalex.org/I205237279","display_name":"Nankai University","ror":"https://ror.org/01y1kjr75","country_code":"CN","type":"education","lineage":["https://openalex.org/I205237279"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xin Zhao","raw_affiliation_strings":["Institute of Robotics and Automatic Information System (IRAIS), Nankai University, Tianjin, China","Tianjin Key Laboratory of Intelligent Robotic (tjKLIR), Nankai University, Tianjin, China"],"raw_orcid":"https://orcid.org/0000-0003-0631-4628","affiliations":[{"raw_affiliation_string":"Institute of Robotics and Automatic Information System (IRAIS), Nankai University, Tianjin, China","institution_ids":["https://openalex.org/I205237279"]},{"raw_affiliation_string":"Tianjin Key Laboratory of Intelligent Robotic (tjKLIR), Nankai University, Tianjin, China","institution_ids":["https://openalex.org/I205237279"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5033177522","display_name":"Mingzhu Sun","orcid":"https://orcid.org/0000-0002-9179-9668"},"institutions":[{"id":"https://openalex.org/I205237279","display_name":"Nankai University","ror":"https://ror.org/01y1kjr75","country_code":"CN","type":"education","lineage":["https://openalex.org/I205237279"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Mingzhu Sun","raw_affiliation_strings":["Institute of Robotics and Automatic Information System (IRAIS), Nankai University, Tianjin, China","Tianjin Key Laboratory of Intelligent Robotic (tjKLIR), Nankai University, Tianjin, China"],"raw_orcid":"https://orcid.org/0000-0002-9179-9668","affiliations":[{"raw_affiliation_string":"Institute of Robotics and Automatic Information System (IRAIS), Nankai University, Tianjin, China","institution_ids":["https://openalex.org/I205237279"]},{"raw_affiliation_string":"Tianjin Key Laboratory of Intelligent Robotic (tjKLIR), Nankai University, Tianjin, China","institution_ids":["https://openalex.org/I205237279"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I205237279"],"apc_list":null,"apc_paid":null,"fwci":1.707,"has_fulltext":false,"cited_by_count":28,"citation_normalized_percentile":{"value":0.83059799,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":99},"biblio":{"volume":"17","issue":"4","first_page":"2097","last_page":"2106"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11255","display_name":"Microfluidic and Bio-sensing Technologies","score":0.9979000091552734,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11255","display_name":"Microfluidic and Bio-sensing Technologies","score":0.9979000091552734,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12140","display_name":"Renal and related cancers","score":0.9868999719619751,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10725","display_name":"RNA Interference and Gene Delivery","score":0.9832000136375427,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/somatic-cell-nuclear-transfer","display_name":"Somatic cell nuclear transfer","score":0.975445032119751},{"id":"https://openalex.org/keywords/cloning","display_name":"Cloning (programming)","score":0.5568196773529053},{"id":"https://openalex.org/keywords/process","display_name":"Process (computing)","score":0.5403585433959961},{"id":"https://openalex.org/keywords/pipette","display_name":"Pipette","score":0.45088398456573486},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.2381819486618042},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.2339380383491516},{"id":"https://openalex.org/keywords/cell-biology","display_name":"Cell biology","score":0.2232581079006195},{"id":"https://openalex.org/keywords/embryo","display_name":"Embryo","score":0.19683358073234558},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.16258728504180908},{"id":"https://openalex.org/keywords/operating-system","display_name":"Operating system","score":0.08033913373947144},{"id":"https://openalex.org/keywords/embryogenesis","display_name":"Embryogenesis","score":0.06823143362998962},{"id":"https://openalex.org/keywords/blastocyst","display_name":"Blastocyst","score":0.06780403852462769}],"concepts":[{"id":"https://openalex.org/C202438428","wikidata":"https://www.wikidata.org/wiki/Q1939923","display_name":"Somatic cell nuclear transfer","level":5,"score":0.975445032119751},{"id":"https://openalex.org/C121050878","wikidata":"https://www.wikidata.org/wiki/Q5135020","display_name":"Cloning (programming)","level":2,"score":0.5568196773529053},{"id":"https://openalex.org/C98045186","wikidata":"https://www.wikidata.org/wiki/Q205663","display_name":"Process (computing)","level":2,"score":0.5403585433959961},{"id":"https://openalex.org/C151552171","wikidata":"https://www.wikidata.org/wiki/Q163373","display_name":"Pipette","level":2,"score":0.45088398456573486},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.2381819486618042},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2339380383491516},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.2232581079006195},{"id":"https://openalex.org/C196843134","wikidata":"https://www.wikidata.org/wiki/Q33196","display_name":"Embryo","level":2,"score":0.19683358073234558},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.16258728504180908},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.08033913373947144},{"id":"https://openalex.org/C87073359","wikidata":"https://www.wikidata.org/wiki/Q33196","display_name":"Embryogenesis","level":3,"score":0.06823143362998962},{"id":"https://openalex.org/C2778177303","wikidata":"https://www.wikidata.org/wiki/Q227717","display_name":"Blastocyst","level":4,"score":0.06780403852462769},{"id":"https://openalex.org/C147789679","wikidata":"https://www.wikidata.org/wiki/Q11372","display_name":"Physical chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/tase.2020.2989760","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tase.2020.2989760","pdf_url":null,"source":{"id":"https://openalex.org/S34881539","display_name":"IEEE Transactions on Automation Science and Engineering","issn_l":"1545-5955","issn":["1545-5955","1558-3783"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Automation Science and Engineering","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/9","score":0.4300000071525574,"display_name":"Industry, innovation and infrastructure"}],"awards":[{"id":"https://openalex.org/G1192599926","display_name":null,"funder_award_id":"18JCZDJC39100","funder_id":"https://openalex.org/F4320323993","funder_display_name":"Natural Science Foundation of Tianjin City"},{"id":"https://openalex.org/G1460046940","display_name":null,"funder_award_id":"61903201","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G229567305","display_name":null,"funder_award_id":"1613220","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G3305018069","display_name":null,"funder_award_id":"18JCYBJC19000","funder_id":"https://openalex.org/F4320323993","funder_display_name":"Natural Science Foundation of Tianjin City"},{"id":"https://openalex.org/G521621494","display_name":null,"funder_award_id":"U1813210","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320323993","display_name":"Natural Science Foundation of Tianjin City","ror":null}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":32,"referenced_works":["https://openalex.org/W1537543043","https://openalex.org/W1861128476","https://openalex.org/W1963559963","https://openalex.org/W1970894097","https://openalex.org/W1989100148","https://openalex.org/W1996365802","https://openalex.org/W2012003773","https://openalex.org/W2048176578","https://openalex.org/W2070328424","https://openalex.org/W2078631909","https://openalex.org/W2088419464","https://openalex.org/W2111405623","https://openalex.org/W2119156836","https://openalex.org/W2120356183","https://openalex.org/W2129316164","https://openalex.org/W2136101105","https://openalex.org/W2145408377","https://openalex.org/W2318456191","https://openalex.org/W2473719885","https://openalex.org/W2544604013","https://openalex.org/W2562629073","https://openalex.org/W2590501734","https://openalex.org/W2592120569","https://openalex.org/W2597361787","https://openalex.org/W2736923812","https://openalex.org/W2773486315","https://openalex.org/W2787097144","https://openalex.org/W2789877998","https://openalex.org/W2790043270","https://openalex.org/W2903927617","https://openalex.org/W4246681734","https://openalex.org/W6632289572"],"related_works":["https://openalex.org/W2109007429","https://openalex.org/W2773168730","https://openalex.org/W2094233277","https://openalex.org/W2394145865","https://openalex.org/W1040126925","https://openalex.org/W1999601483","https://openalex.org/W2008627656","https://openalex.org/W3157705771","https://openalex.org/W2483446547","https://openalex.org/W4315606387"],"abstract_inverted_index":{"Somatic":[0],"cell":[1],"nuclear":[2],"transfer":[3],"(SCNT),":[4],"which":[5,104,154],"is":[6],"an":[7],"important":[8],"procedure":[9],"in":[10,23,47,76],"cloning,":[11],"has":[12],"been":[13],"conducted":[14],"manually":[15],"for":[16],"decades.":[17],"The":[18,160],"operating":[19,40,52,85,107],"efficiency":[20,171],"drops":[21],"sharply":[22],"batch":[24,65,116,163],"SCNT":[25,46,66,82,95,164],"because":[26],"of":[27,138,147,170],"the":[28,34,39,50,84,113,125],"long-time":[29],"observation":[30],"under":[31],"microscopy":[32],"and":[33,73,91,99,143,172],"time-wasting":[35],"traditional":[36,51,94],"process.":[37,159],"Though":[38],"time":[41],"was":[42,54,102],"reduced":[43,118],"by":[44],"robotic":[45,64,115,162],"previous":[48],"studies,":[49],"process":[53,67,96,117,127],"still":[55],"used.":[56],"In":[57],"this":[58,80],"article,":[59],"we":[60],"designed":[61],"a":[62,70,144,167],"new":[63,81,114,161],"based":[68],"on":[69,93],"microfluidic":[71],"groove":[72],"two":[74],"micropipettes":[75],"parallel.":[77],"By":[78],"using":[79],"process,":[83],"area":[86],"switching,":[87],"objective":[88],"lens":[89],"conversing,":[90],"focusing":[92],"were":[97,149,155],"eliminated,":[98],"oocyte":[100],"localization":[101],"simplified,":[103],"saved":[105],"much":[106],"time.":[108],"Experimental":[109],"results":[110],"showed":[111],"that":[112],"about":[119],"50":[120],"s":[121,130],"(41.7%)":[122],"compared":[123],"with":[124],"manual":[126,132,158],"(proposed":[128],"70":[129],"versus":[131],"120":[133],"s).":[134],"A":[135],"success":[136],"rate":[137,146],"93.3%":[139],"(n":[140,151],"=":[141,152],"30)":[142],"survival":[145],"96.4%":[148],"achieved":[150],"28),":[153],"similar":[156],"to":[157],"method":[165],"demonstrated":[166],"high":[168],"degree":[169],"reproducibility.":[173]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":7},{"year":2022,"cited_by_count":7},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":3}],"updated_date":"2026-03-27T05:58:40.876381","created_date":"2025-10-10T00:00:00"}