{"id":"https://openalex.org/W4396215602","doi":"https://doi.org/10.1109/ssiai59505.2024.10508613","title":"Detection and Segmentation Of Shape-Coded Particles Via Hough Transforms and Snake Active Contours","display_name":"Detection and Segmentation Of Shape-Coded Particles Via Hough Transforms and Snake Active Contours","publication_year":2024,"publication_date":"2024-03-17","ids":{"openalex":"https://openalex.org/W4396215602","doi":"https://doi.org/10.1109/ssiai59505.2024.10508613"},"language":"en","primary_location":{"id":"doi:10.1109/ssiai59505.2024.10508613","is_oa":false,"landing_page_url":"https://doi.org/10.1109/ssiai59505.2024.10508613","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2024 IEEE Southwest Symposium on Image Analysis and Interpretation (SSIAI)","raw_type":"proceedings-article"},"type":"conference-paper","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://escholarship.org/content/qt0n54c6xm/qt0n54c6xm.pdf?t=sfykir","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5045473830","display_name":"Jason I. Brown","orcid":"https://orcid.org/0000-0002-4721-8985"},"institutions":[{"id":"https://openalex.org/I142207940","display_name":"California NanoSystems Institute","ror":"https://ror.org/00q7fqf35","country_code":"US","type":"facility","lineage":["https://openalex.org/I142207940","https://openalex.org/I154570441","https://openalex.org/I161318765"]},{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jason Brown","raw_affiliation_strings":["University of California, Los Angeles,Department of Mathematics,Los Angeles,USA,CA 90095","California NanoSystems Institute, University of California, Los Angeles, Los Angeles, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of California, Los Angeles,Department of Mathematics,Los Angeles,USA,CA 90095","institution_ids":["https://openalex.org/I161318765"]},{"raw_affiliation_string":"California NanoSystems Institute, University of California, Los Angeles, Los Angeles, USA","institution_ids":["https://openalex.org/I142207940","https://openalex.org/I161318765"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067773284","display_name":"Alyssa Arnheim","orcid":null},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alyssa Arnheim","raw_affiliation_strings":["University of California, Los Angeles,Department of Mathematics,Los Angeles,USA,CA 90095"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of California, Los Angeles,Department of Mathematics,Los Angeles,USA,CA 90095","institution_ids":["https://openalex.org/I161318765"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090707978","display_name":"Andrea L. Bertozzi","orcid":"https://orcid.org/0000-0003-0396-7391"},"institutions":[{"id":"https://openalex.org/I142207940","display_name":"California NanoSystems Institute","ror":"https://ror.org/00q7fqf35","country_code":"US","type":"facility","lineage":["https://openalex.org/I142207940","https://openalex.org/I154570441","https://openalex.org/I161318765"]},{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Andrea L. Bertozzi","raw_affiliation_strings":["University of California, Los Angeles,Department of Mathematics,Los Angeles,USA,CA 90095","Department of Mechanical and Aerospace Engineering, University of California, Los Angeles, Los Angeles, USA","California NanoSystems Institute, University of California, Los Angeles, Los Angeles, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of California, Los Angeles,Department of Mathematics,Los Angeles,USA,CA 90095","institution_ids":["https://openalex.org/I161318765"]},{"raw_affiliation_string":"Department of Mechanical and Aerospace Engineering, University of California, Los Angeles, Los Angeles, USA","institution_ids":["https://openalex.org/I161318765"]},{"raw_affiliation_string":"California NanoSystems Institute, University of California, Los Angeles, Los Angeles, USA","institution_ids":["https://openalex.org/I142207940","https://openalex.org/I161318765"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5087323774","display_name":"Dino Di Carlo","orcid":"https://orcid.org/0000-0003-3942-4284"},"institutions":[{"id":"https://openalex.org/I142207940","display_name":"California NanoSystems Institute","ror":"https://ror.org/00q7fqf35","country_code":"US","type":"facility","lineage":["https://openalex.org/I142207940","https://openalex.org/I154570441","https://openalex.org/I161318765"]},{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dino D Carlo","raw_affiliation_strings":["University of California, Los Angeles,Department of Bioengineering,Los Angeles,USA,CA 90095","California NanoSystems Institute, University of California, Los Angeles, Los Angeles, USA","Department of Mechanical and Aerospace Engineering, University of California, Los Angeles, Los Angeles, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of California, Los Angeles,Department of Bioengineering,Los Angeles,USA,CA 90095","institution_ids":["https://openalex.org/I161318765"]},{"raw_affiliation_string":"California NanoSystems Institute, University of California, Los Angeles, Los Angeles, USA","institution_ids":["https://openalex.org/I142207940","https://openalex.org/I161318765"]},{"raw_affiliation_string":"Department of Mechanical and Aerospace Engineering, University of California, Los Angeles, Los Angeles, USA","institution_ids":["https://openalex.org/I161318765"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"85","last_page":"88"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12549","display_name":"Image and Object Detection Techniques","score":0.9987000226974487,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T12549","display_name":"Image and Object Detection Techniques","score":0.9987000226974487,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.9926000237464905,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12874","display_name":"Digital Imaging for Blood Diseases","score":0.9915000200271606,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/segmentation","display_name":"Segmentation","score":0.6823995113372803},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.6677894592285156},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6209819316864014},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.5365054607391357},{"id":"https://openalex.org/keywords/hough-transform","display_name":"Hough transform","score":0.5170617699623108},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.5016601085662842},{"id":"https://openalex.org/keywords/active-contour-model","display_name":"Active contour model","score":0.5007476806640625},{"id":"https://openalex.org/keywords/particle-swarm-optimization","display_name":"Particle swarm optimization","score":0.46895474195480347},{"id":"https://openalex.org/keywords/particle","display_name":"Particle (ecology)","score":0.4454878270626068},{"id":"https://openalex.org/keywords/point","display_name":"Point (geometry)","score":0.41594916582107544},{"id":"https://openalex.org/keywords/image-segmentation","display_name":"Image segmentation","score":0.38136401772499084},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.3385222554206848},{"id":"https://openalex.org/keywords/biological-system","display_name":"Biological system","score":0.3362486958503723},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.1714630424976349},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.1417466104030609},{"id":"https://openalex.org/keywords/geometry","display_name":"Geometry","score":0.12585672736167908},{"id":"https://openalex.org/keywords/image","display_name":"Image (mathematics)","score":0.09059754014015198},{"id":"https://openalex.org/keywords/geology","display_name":"Geology","score":0.08230575919151306}],"concepts":[{"id":"https://openalex.org/C89600930","wikidata":"https://www.wikidata.org/wiki/Q1423946","display_name":"Segmentation","level":2,"score":0.6823995113372803},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.6677894592285156},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6209819316864014},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.5365054607391357},{"id":"https://openalex.org/C200518788","wikidata":"https://www.wikidata.org/wiki/Q195076","display_name":"Hough transform","level":3,"score":0.5170617699623108},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.5016601085662842},{"id":"https://openalex.org/C112353826","wikidata":"https://www.wikidata.org/wiki/Q127313","display_name":"Active contour model","level":4,"score":0.5007476806640625},{"id":"https://openalex.org/C85617194","wikidata":"https://www.wikidata.org/wiki/Q2072794","display_name":"Particle swarm optimization","level":2,"score":0.46895474195480347},{"id":"https://openalex.org/C2778517922","wikidata":"https://www.wikidata.org/wiki/Q7140482","display_name":"Particle (ecology)","level":2,"score":0.4454878270626068},{"id":"https://openalex.org/C28719098","wikidata":"https://www.wikidata.org/wiki/Q44946","display_name":"Point (geometry)","level":2,"score":0.41594916582107544},{"id":"https://openalex.org/C124504099","wikidata":"https://www.wikidata.org/wiki/Q56933","display_name":"Image segmentation","level":3,"score":0.38136401772499084},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.3385222554206848},{"id":"https://openalex.org/C186060115","wikidata":"https://www.wikidata.org/wiki/Q30336093","display_name":"Biological system","level":1,"score":0.3362486958503723},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.1714630424976349},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.1417466104030609},{"id":"https://openalex.org/C2524010","wikidata":"https://www.wikidata.org/wiki/Q8087","display_name":"Geometry","level":1,"score":0.12585672736167908},{"id":"https://openalex.org/C115961682","wikidata":"https://www.wikidata.org/wiki/Q860623","display_name":"Image (mathematics)","level":2,"score":0.09059754014015198},{"id":"https://openalex.org/C127313418","wikidata":"https://www.wikidata.org/wiki/Q1069","display_name":"Geology","level":0,"score":0.08230575919151306},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C111368507","wikidata":"https://www.wikidata.org/wiki/Q43518","display_name":"Oceanography","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1109/ssiai59505.2024.10508613","is_oa":false,"landing_page_url":"https://doi.org/10.1109/ssiai59505.2024.10508613","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2024 IEEE Southwest Symposium on Image Analysis and Interpretation (SSIAI)","raw_type":"proceedings-article"},{"id":"pmh:oai:escholarship.org:ark:/13030/qt0n54c6xm","is_oa":true,"landing_page_url":"https://escholarship.org/uc/item/0n54c6xm","pdf_url":"https://escholarship.org/content/qt0n54c6xm/qt0n54c6xm.pdf?t=sfykir","source":{"id":"https://openalex.org/S4306400115","display_name":"eScholarship (California Digital Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I2801248553","host_organization_name":"California Digital Library","host_organization_lineage":["https://openalex.org/I2801248553"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"article"}],"best_oa_location":{"id":"pmh:oai:escholarship.org:ark:/13030/qt0n54c6xm","is_oa":true,"landing_page_url":"https://escholarship.org/uc/item/0n54c6xm","pdf_url":"https://escholarship.org/content/qt0n54c6xm/qt0n54c6xm.pdf?t=sfykir","source":{"id":"https://openalex.org/S4306400115","display_name":"eScholarship (California Digital Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I2801248553","host_organization_name":"California Digital Library","host_organization_lineage":["https://openalex.org/I2801248553"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"article"},"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320308612","display_name":"PATH","ror":"https://ror.org/02ycvrx49"}],"has_content":{"pdf":true,"grobid_xml":false},"content_urls":{"pdf":"https://content.openalex.org/works/W4396215602.pdf"},"referenced_works_count":13,"referenced_works":["https://openalex.org/W42608107","https://openalex.org/W2086921140","https://openalex.org/W2095905764","https://openalex.org/W2104095591","https://openalex.org/W2145023731","https://openalex.org/W2160094774","https://openalex.org/W2422023563","https://openalex.org/W2900434404","https://openalex.org/W3083792079","https://openalex.org/W4211170080","https://openalex.org/W4387537944","https://openalex.org/W4387568499","https://openalex.org/W4387779138"],"related_works":["https://openalex.org/W2030098947","https://openalex.org/W1974777989","https://openalex.org/W2003466055","https://openalex.org/W2363834444","https://openalex.org/W2070077862","https://openalex.org/W2765199790","https://openalex.org/W2164944168","https://openalex.org/W2885157826","https://openalex.org/W2159463658","https://openalex.org/W4388208420"],"abstract_inverted_index":{"Shape-coded":[0],"particles":[1,23,107,152],"enable":[2],"multiplexed":[3],"diagnostics,":[4],"offering":[5],"advantages":[6],"such":[7],"as":[8],"reduced":[9],"reagent":[10],"usage,":[11],"enhanced":[12],"accuracy":[13],"through":[14],"swarm-sensing,":[15],"and":[16,108,127,133,136,149],"decreased":[17],"reliance":[18],"on":[19],"spectral":[20],"barcoding.":[21],"These":[22],"exhibit":[24],"the":[25,33,54,58,79,93,106,113,120,151],"capability":[26],"to":[27,73,91,101],"stabilize":[28],"nanoliter":[29],"aqueous":[30],"droplets":[31,51],"in":[32,57,85],"inner":[34],"annular":[35],"region,":[36],"facilitating":[37],"signal":[38],"amplification":[39],"while":[40,111],"maintaining":[41],"independent":[42],"particle-based":[43],"reactions.":[44],"The":[45],"resulting":[46],"endpoint":[47],"fluorescence":[48],"of":[49,81,95],"these":[50,144],"correlates":[52],"with":[53],"biomarker":[55],"concentration":[56],"patient":[59],"sample,":[60],"providing":[61],"valuable":[62],"information":[63,84],"for":[64,104,131],"disease":[65],"diagnosis.":[66],"Each":[67],"distinct":[68],"shape":[69],"can":[70,146],"be":[71],"assigned":[72],"different":[74],"patients":[75],"or":[76],"biomarkers,":[77],"enabling":[78],"collection":[80],"more":[82],"comprehensive":[83],"each":[86],"diagnostic":[87],"test.":[88],"In":[89,115],"order":[90],"automate":[92],"process":[94],"measuring":[96],"fluorescence,":[97],"it":[98],"is":[99],"necessary":[100],"develop":[102],"methods":[103,145],"detecting":[105],"segmenting":[109,134],"them":[110],"differentiating":[112],"shapes.":[114],"this":[116],"paper,":[117],"we":[118],"use":[119],"circle":[121,135],"Hough":[122],"Transform,":[123],"square":[124,137],"template":[125],"matching,":[126],"snake":[128],"active":[129],"contours":[130],"distinguishing":[132],"particles.":[138],"Without":[139],"using":[140],"any":[141],"deep":[142],"learning,":[143],"successfully":[147],"identify":[148],"segment":[150],"under":[153],"various":[154],"conditions.":[155]},"counts_by_year":[{"year":2025,"cited_by_count":1}],"updated_date":"2026-07-23T08:03:31.855105","created_date":"2025-10-10T00:00:00"}