{"id":"https://openalex.org/W4206958438","doi":"https://doi.org/10.1109/ssci50451.2021.9659958","title":"Incremental & Semi-Supervised Learning for Functional Analysis of Protein Sequences","display_name":"Incremental & Semi-Supervised Learning for Functional Analysis of Protein Sequences","publication_year":2021,"publication_date":"2021-12-05","ids":{"openalex":"https://openalex.org/W4206958438","doi":"https://doi.org/10.1109/ssci50451.2021.9659958"},"language":"en","primary_location":{"id":"doi:10.1109/ssci50451.2021.9659958","is_oa":false,"landing_page_url":"https://doi.org/10.1109/ssci50451.2021.9659958","pdf_url":null,"source":{"id":"https://openalex.org/S4363604921","display_name":"2021 IEEE Symposium Series on Computational Intelligence (SSCI)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"conference"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2021 IEEE Symposium Series on Computational Intelligence (SSCI)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5011297798","display_name":"Mali Halac","orcid":null},"institutions":[{"id":"https://openalex.org/I72816309","display_name":"Drexel University","ror":"https://ror.org/04bdffz58","country_code":"US","type":"education","lineage":["https://openalex.org/I72816309"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Mali Halac","raw_affiliation_strings":["Drexel University,Electrical and Computer Eng.,Philadelphia,PA,USA"],"affiliations":[{"raw_affiliation_string":"Drexel University,Electrical and Computer Eng.,Philadelphia,PA,USA","institution_ids":["https://openalex.org/I72816309"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038775063","display_name":"Bahrad A. Sokhansanj","orcid":"https://orcid.org/0000-0002-5050-5926"},"institutions":[{"id":"https://openalex.org/I72816309","display_name":"Drexel University","ror":"https://ror.org/04bdffz58","country_code":"US","type":"education","lineage":["https://openalex.org/I72816309"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Bahrad Sokhansanj","raw_affiliation_strings":["Drexel University,Electrical and Computer Eng.,Philadelphia,PA,USA"],"affiliations":[{"raw_affiliation_string":"Drexel University,Electrical and Computer Eng.,Philadelphia,PA,USA","institution_ids":["https://openalex.org/I72816309"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067783602","display_name":"W. Trimble","orcid":"https://orcid.org/0000-0001-7029-2676"},"institutions":[{"id":"https://openalex.org/I40347166","display_name":"University of Chicago","ror":"https://ror.org/024mw5h28","country_code":"US","type":"education","lineage":["https://openalex.org/I40347166"]},{"id":"https://openalex.org/I1282105669","display_name":"Argonne National Laboratory","ror":"https://ror.org/05gvnxz63","country_code":"US","type":"facility","lineage":["https://openalex.org/I1282105669","https://openalex.org/I1330989302","https://openalex.org/I39565521","https://openalex.org/I40347166"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"William L. Trimble","raw_affiliation_strings":["University of Chicago,Argonne National Laboratory,Chicago,IL,USA","Argonne National Laboratory, University of Chicago, Chicago, IL, USA"],"affiliations":[{"raw_affiliation_string":"University of Chicago,Argonne National Laboratory,Chicago,IL,USA","institution_ids":["https://openalex.org/I1282105669"]},{"raw_affiliation_string":"Argonne National Laboratory, University of Chicago, Chicago, IL, USA","institution_ids":["https://openalex.org/I1282105669","https://openalex.org/I40347166"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027764023","display_name":"Thomas Coard","orcid":null},"institutions":[{"id":"https://openalex.org/I72816309","display_name":"Drexel University","ror":"https://ror.org/04bdffz58","country_code":"US","type":"education","lineage":["https://openalex.org/I72816309"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Thomas Coard","raw_affiliation_strings":["Drexel University,Electrical and Computer Eng.,Philadelphia,PA,USA"],"affiliations":[{"raw_affiliation_string":"Drexel University,Electrical and Computer Eng.,Philadelphia,PA,USA","institution_ids":["https://openalex.org/I72816309"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034370901","display_name":"Norman C. Sabin","orcid":null},"institutions":[{"id":"https://openalex.org/I44265643","display_name":"Rowan University","ror":"https://ror.org/049v69k10","country_code":"US","type":"education","lineage":["https://openalex.org/I44265643"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Norman C. Sabin","raw_affiliation_strings":["Rowan University,Electrical and Computer Eng.,Glassboro,NJ,USA"],"affiliations":[{"raw_affiliation_string":"Rowan University,Electrical and Computer Eng.,Glassboro,NJ,USA","institution_ids":["https://openalex.org/I44265643"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039169012","display_name":"Emrecan Ozdogan","orcid":null},"institutions":[{"id":"https://openalex.org/I44265643","display_name":"Rowan University","ror":"https://ror.org/049v69k10","country_code":"US","type":"education","lineage":["https://openalex.org/I44265643"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Emrecan Ozdogan","raw_affiliation_strings":["Rowan University,Electrical and Computer Eng.,Glassboro,NJ,USA"],"affiliations":[{"raw_affiliation_string":"Rowan University,Electrical and Computer Eng.,Glassboro,NJ,USA","institution_ids":["https://openalex.org/I44265643"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025314990","display_name":"Robi Polikar","orcid":"https://orcid.org/0000-0002-2739-4228"},"institutions":[{"id":"https://openalex.org/I44265643","display_name":"Rowan University","ror":"https://ror.org/049v69k10","country_code":"US","type":"education","lineage":["https://openalex.org/I44265643"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robi Polikar","raw_affiliation_strings":["Rowan University,Electrical and Computer Eng.,Glassboro,NJ,USA"],"affiliations":[{"raw_affiliation_string":"Rowan University,Electrical and Computer Eng.,Glassboro,NJ,USA","institution_ids":["https://openalex.org/I44265643"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5023224900","display_name":"Gail Rosen","orcid":"https://orcid.org/0000-0003-1763-5750"},"institutions":[{"id":"https://openalex.org/I72816309","display_name":"Drexel University","ror":"https://ror.org/04bdffz58","country_code":"US","type":"education","lineage":["https://openalex.org/I72816309"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gail L. Rosen","raw_affiliation_strings":["Drexel University,Electrical and Computer Eng.,Philadelphia,PA,USA"],"affiliations":[{"raw_affiliation_string":"Drexel University,Electrical and Computer Eng.,Philadelphia,PA,USA","institution_ids":["https://openalex.org/I72816309"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5011297798"],"corresponding_institution_ids":["https://openalex.org/I72816309"],"apc_list":null,"apc_paid":null,"fwci":2.0751,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.87546468,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":96,"max":97},"biblio":{"volume":null,"issue":null,"first_page":"01","last_page":"08"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9955000281333923,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/classifier","display_name":"Classifier (UML)","score":0.7941455841064453},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7415685653686523},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.6166389584541321},{"id":"https://openalex.org/keywords/annotation","display_name":"Annotation","score":0.6074535250663757},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.5464252233505249},{"id":"https://openalex.org/keywords/incremental-learning","display_name":"Incremental learning","score":0.49351251125335693},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.39788565039634705},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.36630016565322876}],"concepts":[{"id":"https://openalex.org/C95623464","wikidata":"https://www.wikidata.org/wiki/Q1096149","display_name":"Classifier (UML)","level":2,"score":0.7941455841064453},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7415685653686523},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.6166389584541321},{"id":"https://openalex.org/C2776321320","wikidata":"https://www.wikidata.org/wiki/Q857525","display_name":"Annotation","level":2,"score":0.6074535250663757},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.5464252233505249},{"id":"https://openalex.org/C2780735816","wikidata":"https://www.wikidata.org/wiki/Q28324931","display_name":"Incremental learning","level":2,"score":0.49351251125335693},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.39788565039634705},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.36630016565322876}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/ssci50451.2021.9659958","is_oa":false,"landing_page_url":"https://doi.org/10.1109/ssci50451.2021.9659958","pdf_url":null,"source":{"id":"https://openalex.org/S4363604921","display_name":"2021 IEEE Symposium Series on Computational Intelligence (SSCI)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"conference"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2021 IEEE Symposium Series on Computational Intelligence (SSCI)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320310343","display_name":"Drexel University","ror":"https://ror.org/04bdffz58"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":17,"referenced_works":["https://openalex.org/W1990453950","https://openalex.org/W2003144438","https://openalex.org/W2041386815","https://openalex.org/W2045204781","https://openalex.org/W2103017472","https://openalex.org/W2132926880","https://openalex.org/W2133790733","https://openalex.org/W2461568883","https://openalex.org/W2755432955","https://openalex.org/W3006857117","https://openalex.org/W3014763446","https://openalex.org/W3016767494","https://openalex.org/W3087226231","https://openalex.org/W3100584158","https://openalex.org/W3101667854","https://openalex.org/W3112600195","https://openalex.org/W3143063265"],"related_works":["https://openalex.org/W2361861616","https://openalex.org/W2263699433","https://openalex.org/W2377979023","https://openalex.org/W2218034408","https://openalex.org/W2392921965","https://openalex.org/W2358755282","https://openalex.org/W2625833328","https://openalex.org/W1533177136","https://openalex.org/W1834658692","https://openalex.org/W2885226678"],"abstract_inverted_index":{"Current":[0],"approaches":[1],"for":[2,85],"the":[3,24,27,36,43,60,86],"functional":[4,87],"annotation":[5],"of":[6,26,46,67,89],"proteins":[7],"rely":[8],"on":[9,14,64],"training":[10],"a":[11,15,65,83,97],"classifier":[12,61,84],"based":[13,63],"fixed":[16],"reference":[17,28],"database.":[18],"As":[19],"more":[20],"genes":[21],"are":[22,33],"sequenced,":[23],"size":[25],"database":[29],"grows":[30],"and":[31,38,77],"classifiers":[32],"retrained":[34],"with":[35],"old":[37],"some":[39],"new":[40],"data.":[41,68],"Considering":[42],"ever-increasing":[44],"number":[45],"(meta-)genomic":[47],"data,":[48],"repeating":[49],"this":[50,71],"process":[51],"is":[52,57],"computationally":[53],"expensive.":[54],"An":[55],"alternative":[56],"to":[58,81,95],"update":[59],"continuously":[62],"stream":[66],"Thus,":[69],"in":[70,105],"study,":[72],"we":[73],"propose":[74],"an":[75],"incremental":[76],"semi-supervised":[78],"learning":[79],"approach":[80],"train":[82],"analysis":[88],"protein":[90,107],"sequences.":[91],"Our":[92],"method":[93],"proves":[94],"have":[96],"low":[98],"computational":[99],"cost":[100],"while":[101],"maintaining":[102],"high":[103],"accuracy":[104],"nredicting":[106],"functions.":[108]},"counts_by_year":[{"year":2023,"cited_by_count":4}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}