{"id":"https://openalex.org/W2609159228","doi":"https://doi.org/10.1109/socc.2016.7905444","title":"Multi-objective sample preparation algorithm for microfluidic biochips supporting various mixing models","display_name":"Multi-objective sample preparation algorithm for microfluidic biochips supporting various mixing models","publication_year":2016,"publication_date":"2016-09-01","ids":{"openalex":"https://openalex.org/W2609159228","doi":"https://doi.org/10.1109/socc.2016.7905444","mag":"2609159228"},"language":"en","primary_location":{"id":"doi:10.1109/socc.2016.7905444","is_oa":false,"landing_page_url":"https://doi.org/10.1109/socc.2016.7905444","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2016 29th IEEE International System-on-Chip Conference (SOCC)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5037955640","display_name":"Yung-Chun Lei","orcid":null},"institutions":[{"id":"https://openalex.org/I148366613","display_name":"National Yang Ming Chiao Tung University","ror":"https://ror.org/00se2k293","country_code":"TW","type":"education","lineage":["https://openalex.org/I148366613"]}],"countries":["TW"],"is_corresponding":true,"raw_author_name":"Yung-Chun Lei","raw_affiliation_strings":["Department of Electronics Engineering, National Chiao Tung University, Taiwan"],"affiliations":[{"raw_affiliation_string":"Department of Electronics Engineering, National Chiao Tung University, Taiwan","institution_ids":["https://openalex.org/I148366613"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067239444","display_name":"Tung-Hsuan Lin","orcid":null},"institutions":[{"id":"https://openalex.org/I4210148979","display_name":"MediaTek (Taiwan)","ror":"https://ror.org/05g9jck81","country_code":"TW","type":"company","lineage":["https://openalex.org/I4210148979"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Tung-Hsuan Lin","raw_affiliation_strings":["MediaTek Inc., Taiwan"],"affiliations":[{"raw_affiliation_string":"MediaTek Inc., Taiwan","institution_ids":["https://openalex.org/I4210148979"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5107969989","display_name":"Juinn-Dar Huang","orcid":"https://orcid.org/0000-0001-5961-7863"},"institutions":[{"id":"https://openalex.org/I148366613","display_name":"National Yang Ming Chiao Tung University","ror":"https://ror.org/00se2k293","country_code":"TW","type":"education","lineage":["https://openalex.org/I148366613"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Juinn-Dar Huang","raw_affiliation_strings":["Department of Electronics Engineering, National Chiao Tung University, Taiwan"],"affiliations":[{"raw_affiliation_string":"Department of Electronics Engineering, National Chiao Tung University, Taiwan","institution_ids":["https://openalex.org/I148366613"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5037955640"],"corresponding_institution_ids":["https://openalex.org/I148366613"],"apc_list":null,"apc_paid":null,"fwci":0.5513,"has_fulltext":false,"cited_by_count":8,"citation_normalized_percentile":{"value":0.73040155,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":null,"issue":null,"first_page":"96","last_page":"101"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12452","display_name":"Electrowetting and Microfluidic Technologies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T12452","display_name":"Electrowetting and Microfluidic Technologies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10412","display_name":"Microfluidic and Capillary Electrophoresis Applications","score":0.9979000091552734,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11407","display_name":"Innovative Microfluidic and Catalytic Techniques Innovation","score":0.9969000220298767,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/biochip","display_name":"Biochip","score":0.9754782915115356},{"id":"https://openalex.org/keywords/microfluidics","display_name":"Microfluidics","score":0.8191816806793213},{"id":"https://openalex.org/keywords/mixing","display_name":"Mixing (physics)","score":0.6343163847923279},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6048687696456909},{"id":"https://openalex.org/keywords/sample","display_name":"Sample (material)","score":0.5844048261642456},{"id":"https://openalex.org/keywords/minification","display_name":"Minification","score":0.548332691192627},{"id":"https://openalex.org/keywords/flow","display_name":"Flow (mathematics)","score":0.48287156224250793},{"id":"https://openalex.org/keywords/integer-programming","display_name":"Integer programming","score":0.4589330852031708},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.4112108647823334},{"id":"https://openalex.org/keywords/mathematical-optimization","display_name":"Mathematical optimization","score":0.37504705786705017},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.26261797547340393},{"id":"https://openalex.org/keywords/nanotechnology","display_name":"Nanotechnology","score":0.2136721909046173},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.19619062542915344},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.1157090961933136},{"id":"https://openalex.org/keywords/chromatography","display_name":"Chromatography","score":0.10848879814147949}],"concepts":[{"id":"https://openalex.org/C87892846","wikidata":"https://www.wikidata.org/wiki/Q864256","display_name":"Biochip","level":2,"score":0.9754782915115356},{"id":"https://openalex.org/C8673954","wikidata":"https://www.wikidata.org/wiki/Q138845","display_name":"Microfluidics","level":2,"score":0.8191816806793213},{"id":"https://openalex.org/C138777275","wikidata":"https://www.wikidata.org/wiki/Q6884054","display_name":"Mixing (physics)","level":2,"score":0.6343163847923279},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6048687696456909},{"id":"https://openalex.org/C198531522","wikidata":"https://www.wikidata.org/wiki/Q485146","display_name":"Sample (material)","level":2,"score":0.5844048261642456},{"id":"https://openalex.org/C147764199","wikidata":"https://www.wikidata.org/wiki/Q6865248","display_name":"Minification","level":2,"score":0.548332691192627},{"id":"https://openalex.org/C38349280","wikidata":"https://www.wikidata.org/wiki/Q1434290","display_name":"Flow (mathematics)","level":2,"score":0.48287156224250793},{"id":"https://openalex.org/C56086750","wikidata":"https://www.wikidata.org/wiki/Q6042592","display_name":"Integer programming","level":2,"score":0.4589330852031708},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.4112108647823334},{"id":"https://openalex.org/C126255220","wikidata":"https://www.wikidata.org/wiki/Q141495","display_name":"Mathematical optimization","level":1,"score":0.37504705786705017},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.26261797547340393},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.2136721909046173},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.19619062542915344},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.1157090961933136},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.10848879814147949},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C2524010","wikidata":"https://www.wikidata.org/wiki/Q8087","display_name":"Geometry","level":1,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/socc.2016.7905444","is_oa":false,"landing_page_url":"https://doi.org/10.1109/socc.2016.7905444","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2016 29th IEEE International System-on-Chip Conference (SOCC)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":32,"referenced_works":["https://openalex.org/W1717854081","https://openalex.org/W1980181699","https://openalex.org/W1993190122","https://openalex.org/W2007104312","https://openalex.org/W2008548447","https://openalex.org/W2020086507","https://openalex.org/W2024859618","https://openalex.org/W2032239903","https://openalex.org/W2036702954","https://openalex.org/W2042181447","https://openalex.org/W2052580805","https://openalex.org/W2062409563","https://openalex.org/W2078650887","https://openalex.org/W2084364074","https://openalex.org/W2098665512","https://openalex.org/W2104622925","https://openalex.org/W2109508253","https://openalex.org/W2109834102","https://openalex.org/W2110460556","https://openalex.org/W2128427912","https://openalex.org/W2128897938","https://openalex.org/W2145500519","https://openalex.org/W2157536064","https://openalex.org/W2161283167","https://openalex.org/W2168567259","https://openalex.org/W2172036636","https://openalex.org/W3011891279","https://openalex.org/W4237610050","https://openalex.org/W4240583845","https://openalex.org/W6637490550","https://openalex.org/W6659869445","https://openalex.org/W6683000334"],"related_works":["https://openalex.org/W2364922518","https://openalex.org/W2361860382","https://openalex.org/W1995422305","https://openalex.org/W2379531326","https://openalex.org/W2604557458","https://openalex.org/W2544485685","https://openalex.org/W2353006359","https://openalex.org/W1834829329","https://openalex.org/W2738065864","https://openalex.org/W2757330072"],"abstract_inverted_index":{"Sample":[0],"preparation":[1,53],"is":[2],"one":[3],"of":[4,99],"the":[5,50,71,90,108],"most":[6,10],"crucial":[7],"processes":[8],"in":[9,17,73],"biochemical":[11],"applications.":[12],"Reagents":[13],"are":[14],"repeatedly":[15],"diluted":[16],"an":[18],"appropriate":[19],"sequence":[20],"to":[21],"get":[22],"a":[23,27,74],"target":[24],"solution":[25],"with":[26,58,107],"specific":[28],"concentration":[29],"value.":[30],"For":[31],"flow-based":[32],"microfluidic":[33,56],"biochips":[34,57],"(FMFBs),":[35],"several":[36],"research":[37],"works":[38],"have":[39],"been":[40],"proposed":[41,91],"for":[42,55],"reactant":[43],"minimization.":[44],"In":[45],"this":[46],"paper,":[47],"we":[48],"propose":[49],"first":[51,69],"sample":[52],"algorithm":[54],"various":[59],"mixing":[60],"models":[61],"that":[62,89],"can":[63,93],"perform":[64],"multi-objective":[65],"optimization":[66],"simultaneously.":[67],"It":[68],"formulates":[70],"problem":[72],"network-flow":[75],"model":[76],"and":[77,102],"then":[78],"solves":[79],"it":[80],"through":[81],"integer":[82],"linear":[83],"programming":[84],"(ILP).":[85],"Experimental":[86],"results":[87],"show":[88],"method":[92],"provide":[94],"better":[95],"solutions":[96],"(in":[97],"terms":[98],"reactant,":[100],"waste,":[101],"operation":[103],"jointly)":[104],"as":[105],"compared":[106],"prior":[109],"art.":[110]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}