{"id":"https://openalex.org/W1481785473","doi":"https://doi.org/10.1109/snpd.2015.7176174","title":"A computational study on different penalty approaches for constrained optimization in radiation therapy treatment planning with a simulated annealing algorithm","display_name":"A computational study on different penalty approaches for constrained optimization in radiation therapy treatment planning with a simulated annealing algorithm","publication_year":2015,"publication_date":"2015-06-01","ids":{"openalex":"https://openalex.org/W1481785473","doi":"https://doi.org/10.1109/snpd.2015.7176174","mag":"1481785473"},"language":"en","primary_location":{"id":"doi:10.1109/snpd.2015.7176174","is_oa":false,"landing_page_url":"https://doi.org/10.1109/snpd.2015.7176174","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2015 IEEE/ACIS 16th International Conference on Software Engineering, Artificial Intelligence, Networking and Parallel/Distributed Computing (SNPD)","raw_type":"proceedings-article"},"type":"conference-paper","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5089620066","display_name":"Sadegh Mohammadi","orcid":"https://orcid.org/0000-0001-9763-4963"},"institutions":[{"id":"https://openalex.org/I63772739","display_name":"Florida Atlantic University","ror":"https://ror.org/05p8w6387","country_code":"US","type":"education","lineage":["https://openalex.org/I63772739"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sadegh Mohammadi","raw_affiliation_strings":["Department of Physics, Florida Atlantic University, Boca Raton, FL, USA","Department of Physics, Florida Atlantic University,#N#Boca Raton, FL 33431, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physics, Florida Atlantic University, Boca Raton, FL, USA","institution_ids":["https://openalex.org/I63772739"]},{"raw_affiliation_string":"Department of Physics, Florida Atlantic University,#N#Boca Raton, FL 33431, USA","institution_ids":["https://openalex.org/I63772739"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103277740","display_name":"Charles Shang","orcid":"https://orcid.org/0000-0002-8611-9955"},"institutions":[{"id":"https://openalex.org/I2802769386","display_name":"Boca Raton Regional Hospital","ror":"https://ror.org/01phhgk62","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1302444339","https://openalex.org/I2802769386"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Charles Shang","raw_affiliation_strings":["Boca Raton Regional Hospital, Lynn Cancer Institute, Boca Raton, FL, USA","Lynn Cancer Institute, Boca Raton Regional Hospital Boca Raton, FL, 33431, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Boca Raton Regional Hospital, Lynn Cancer Institute, Boca Raton, FL, USA","institution_ids":["https://openalex.org/I2802769386"]},{"raw_affiliation_string":"Lynn Cancer Institute, Boca Raton Regional Hospital Boca Raton, FL, 33431, USA","institution_ids":["https://openalex.org/I2802769386"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004542912","display_name":"Zoubir Ouhib","orcid":"https://orcid.org/0000-0002-5332-5584"},"institutions":[{"id":"https://openalex.org/I2802769386","display_name":"Boca Raton Regional Hospital","ror":"https://ror.org/01phhgk62","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1302444339","https://openalex.org/I2802769386"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Zoubir Ouhib","raw_affiliation_strings":["Boca Raton Regional Hospital, Lynn Cancer Institute, Boca Raton, FL, USA","Lynn Cancer Institute, Boca Raton Regional Hospital Boca Raton, FL, 33431, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Boca Raton Regional Hospital, Lynn Cancer Institute, Boca Raton, FL, USA","institution_ids":["https://openalex.org/I2802769386"]},{"raw_affiliation_string":"Lynn Cancer Institute, Boca Raton Regional Hospital Boca Raton, FL, 33431, USA","institution_ids":["https://openalex.org/I2802769386"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110489897","display_name":"Theodora Leventouri","orcid":null},"institutions":[{"id":"https://openalex.org/I63772739","display_name":"Florida Atlantic University","ror":"https://ror.org/05p8w6387","country_code":"US","type":"education","lineage":["https://openalex.org/I63772739"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Theodora Leventouri","raw_affiliation_strings":["Department of Physics, Florida Atlantic University, Boca Raton, FL, USA","Department of Physics, Florida Atlantic University,#N#Boca Raton, FL 33431, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physics, Florida Atlantic University, Boca Raton, FL, USA","institution_ids":["https://openalex.org/I63772739"]},{"raw_affiliation_string":"Department of Physics, Florida Atlantic University,#N#Boca Raton, FL 33431, USA","institution_ids":["https://openalex.org/I63772739"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5044182579","display_name":"Georgios Kalantzis","orcid":"https://orcid.org/0000-0002-0729-1125"},"institutions":[{"id":"https://openalex.org/I63772739","display_name":"Florida Atlantic University","ror":"https://ror.org/05p8w6387","country_code":"US","type":"education","lineage":["https://openalex.org/I63772739"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Georgios Kalantzis","raw_affiliation_strings":["Department of Physics, Florida Atlantic University, Boca Raton, FL, USA","Department of Physics, Florida Atlantic University,#N#Boca Raton, FL 33431, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physics, Florida Atlantic University, Boca Raton, FL, USA","institution_ids":["https://openalex.org/I63772739"]},{"raw_affiliation_string":"Department of Physics, Florida Atlantic University,#N#Boca Raton, FL 33431, USA","institution_ids":["https://openalex.org/I63772739"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":8,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"1","last_page":"6"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10358","display_name":"Advanced Radiotherapy Techniques","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/3108","display_name":"Radiation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10358","display_name":"Advanced Radiotherapy Techniques","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/3108","display_name":"Radiation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10124","display_name":"Prostate Cancer Diagnosis and Treatment","score":0.9591000080108643,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10543","display_name":"Prostate Cancer Treatment and Research","score":0.9491000175476074,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/simulated-annealing","display_name":"Simulated annealing","score":0.7776669263839722},{"id":"https://openalex.org/keywords/maxima-and-minima","display_name":"Maxima and minima","score":0.7349433302879333},{"id":"https://openalex.org/keywords/mathematical-optimization","display_name":"Mathematical optimization","score":0.6666402816772461},{"id":"https://openalex.org/keywords/radiation-treatment-planning","display_name":"Radiation treatment planning","score":0.6432828903198242},{"id":"https://openalex.org/keywords/penalty-method","display_name":"Penalty method","score":0.6279407739639282},{"id":"https://openalex.org/keywords/curse-of-dimensionality","display_name":"Curse of dimensionality","score":0.5868833661079407},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5818491578102112},{"id":"https://openalex.org/keywords/adaptive-simulated-annealing","display_name":"Adaptive simulated annealing","score":0.4264601469039917},{"id":"https://openalex.org/keywords/heuristic","display_name":"Heuristic","score":0.4259319007396698},{"id":"https://openalex.org/keywords/constrained-optimization","display_name":"Constrained optimization","score":0.4205995798110962},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.4142061173915863},{"id":"https://openalex.org/keywords/radiation-therapy","display_name":"Radiation therapy","score":0.36904966831207275},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.267808198928833},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.15372759103775024},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.07335337996482849}],"concepts":[{"id":"https://openalex.org/C126980161","wikidata":"https://www.wikidata.org/wiki/Q863783","display_name":"Simulated annealing","level":2,"score":0.7776669263839722},{"id":"https://openalex.org/C186633575","wikidata":"https://www.wikidata.org/wiki/Q845060","display_name":"Maxima and minima","level":2,"score":0.7349433302879333},{"id":"https://openalex.org/C126255220","wikidata":"https://www.wikidata.org/wiki/Q141495","display_name":"Mathematical optimization","level":1,"score":0.6666402816772461},{"id":"https://openalex.org/C201645570","wikidata":"https://www.wikidata.org/wiki/Q830637","display_name":"Radiation treatment planning","level":3,"score":0.6432828903198242},{"id":"https://openalex.org/C6180225","wikidata":"https://www.wikidata.org/wiki/Q3411771","display_name":"Penalty method","level":2,"score":0.6279407739639282},{"id":"https://openalex.org/C111030470","wikidata":"https://www.wikidata.org/wiki/Q1430460","display_name":"Curse of dimensionality","level":2,"score":0.5868833661079407},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5818491578102112},{"id":"https://openalex.org/C46714192","wikidata":"https://www.wikidata.org/wiki/Q4680763","display_name":"Adaptive simulated annealing","level":3,"score":0.4264601469039917},{"id":"https://openalex.org/C173801870","wikidata":"https://www.wikidata.org/wiki/Q201413","display_name":"Heuristic","level":2,"score":0.4259319007396698},{"id":"https://openalex.org/C55660270","wikidata":"https://www.wikidata.org/wiki/Q5164377","display_name":"Constrained optimization","level":2,"score":0.4205995798110962},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.4142061173915863},{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.36904966831207275},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.267808198928833},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.15372759103775024},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.07335337996482849},{"id":"https://openalex.org/C134306372","wikidata":"https://www.wikidata.org/wiki/Q7754","display_name":"Mathematical analysis","level":1,"score":0.0},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/snpd.2015.7176174","is_oa":false,"landing_page_url":"https://doi.org/10.1109/snpd.2015.7176174","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2015 IEEE/ACIS 16th International Conference on Software Engineering, Artificial Intelligence, Networking and Parallel/Distributed Computing (SNPD)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.6899999976158142,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":15,"referenced_works":["https://openalex.org/W135581174","https://openalex.org/W1979542887","https://openalex.org/W1999749445","https://openalex.org/W2001101365","https://openalex.org/W2004617458","https://openalex.org/W2039568841","https://openalex.org/W2041433522","https://openalex.org/W2051823503","https://openalex.org/W2056760934","https://openalex.org/W2072276987","https://openalex.org/W2072723582","https://openalex.org/W2084188360","https://openalex.org/W2088978850","https://openalex.org/W2104133157","https://openalex.org/W3086122947"],"related_works":["https://openalex.org/W2132461435","https://openalex.org/W2077092686","https://openalex.org/W2018668003","https://openalex.org/W2261837478","https://openalex.org/W3007136692","https://openalex.org/W1967687468","https://openalex.org/W2089397391","https://openalex.org/W2002077985","https://openalex.org/W2116432473","https://openalex.org/W1992534732"],"abstract_inverted_index":{"In":[0,130,154],"intensity":[1],"modulated":[2],"radiation":[3,22,89],"therapy":[4],"(IMRT)":[5],"a":[6,10,42,82],"treatment":[7,99,144,172],"plan":[8,37],"is":[9,38,125],"high":[11],"dimensionality":[12],"optimization":[13,44,71,95,114],"problem":[14],"with":[15,150],"the":[16,20,25,50,61,70,79,106,121,128,131,136,164,167,171,175],"goal":[17],"to":[18,24,69,108,162],"give":[19],"prescribed":[21],"dose":[23,56,151],"Planning":[26],"Target":[27],"Volume":[28],"(PTV)":[29],"while":[30],"sparing":[31],"critical":[32],"organs.":[33],"A":[34],"clinically":[35],"acceptable":[36],"usually":[39],"generated":[40],"by":[41],"numerical":[43],"process":[45],"in":[46,78,88,160],"pursuit":[47],"of":[48,55,67,138,166,179],"attaining":[49],"above":[51],"mentioned":[52],"goal.":[53],"Incorporation":[54],"volume":[57,152],"constraints":[58],"(DVCs)":[59],"for":[60,85,112,127,142,146],"OARs":[62],"introduce":[63],"an":[64],"additional":[65],"degree":[66],"impediment":[68],"task.":[72],"Heuristic":[73],"algorithms":[74],"have":[75,182],"been":[76,183],"ascertained":[77],"past":[80],"as":[81,92],"powerful":[83],"tool":[84],"various":[86],"problems":[87],"therapy,":[90],"such":[91],"beam":[93],"angle":[94],"(BAO)":[96],"and":[97,177],"IMRT":[98,143],"planning.":[100],"Simulated":[101],"Annealing":[102],"(SA)":[103],"algorithm":[104],"has":[105],"capability":[107],"find":[109],"global":[110],"minima":[111],"bound-constrained":[113],"problems.":[115],"However,":[116],"its":[117],"performance":[118,137],"depends":[119],"on":[120,170],"penalty":[122,140,168],"method":[123,181],"which":[124],"utilized":[126],"constraints.":[129,153],"current":[132],"study":[133,163],"we":[134],"investigate":[135],"three":[139],"methods":[141],"planning":[145],"five":[147],"prostate":[148],"cases":[149],"addition,":[155],"sensitivity":[156],"analysis":[157],"was":[158],"performed":[159],"order":[161],"effect":[165],"variables":[169],"plan.":[173],"Finally":[174],"merits":[176],"demerits":[178],"each":[180],"discussed.":[184]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":3}],"updated_date":"2026-07-14T23:27:15.235271","created_date":"2025-10-10T00:00:00"}