{"id":"https://openalex.org/W4417472977","doi":"https://doi.org/10.1109/sipaim67325.2025.11283422","title":"Generating diffusion MRI scalar maps from T1-weighted images using Reversible GANs","display_name":"Generating diffusion MRI scalar maps from T1-weighted images using Reversible GANs","publication_year":2025,"publication_date":"2025-11-18","ids":{"openalex":"https://openalex.org/W4417472977","doi":"https://doi.org/10.1109/sipaim67325.2025.11283422"},"language":null,"primary_location":{"id":"doi:10.1109/sipaim67325.2025.11283422","is_oa":false,"landing_page_url":"https://doi.org/10.1109/sipaim67325.2025.11283422","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2025 21st International Symposium on Biomedical Image Processing and Analysis (SIPAIM)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5074576951","display_name":"Tamoghna Chattopadhyay","orcid":"https://orcid.org/0000-0002-3146-6845"},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Tamoghna Chattopadhyay","raw_affiliation_strings":["University of Southern California,Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine,CA,United States"],"affiliations":[{"raw_affiliation_string":"University of Southern California,Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine,CA,United States","institution_ids":["https://openalex.org/I1174212"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5097355264","display_name":"Gautam Mehendale","orcid":null},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gautam Mehendale","raw_affiliation_strings":["University of Southern California,Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine,CA,United States"],"affiliations":[{"raw_affiliation_string":"University of Southern California,Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine,CA,United States","institution_ids":["https://openalex.org/I1174212"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017365268","display_name":"Sophia I. Thomopoulos","orcid":"https://orcid.org/0000-0002-0046-4070"},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sophia I. Thomopoulos","raw_affiliation_strings":["University of Southern California,Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine,CA,United States"],"affiliations":[{"raw_affiliation_string":"University of Southern California,Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine,CA,United States","institution_ids":["https://openalex.org/I1174212"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015551986","display_name":"Himanshu Joshi","orcid":"https://orcid.org/0000-0003-2624-7821"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Himanshu Joshi","raw_affiliation_strings":["Multimodal Brain Image Analysis Laboratory"],"affiliations":[{"raw_affiliation_string":"Multimodal Brain Image Analysis Laboratory","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047157394","display_name":"Ganesan Venkatasubramanian","orcid":"https://orcid.org/0000-0002-0949-898X"},"institutions":[{"id":"https://openalex.org/I699696","display_name":"National Institute of Mental Health and Neurosciences","ror":"https://ror.org/0405n5e57","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I699696"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Ganesan Venkatasubramanian","raw_affiliation_strings":["National Institute of Mental Health and Neuro Sciences (NIMHANS),Translational Psychiatry Laboratory,Bengaluru,Karnataka,India"],"affiliations":[{"raw_affiliation_string":"National Institute of Mental Health and Neuro Sciences (NIMHANS),Translational Psychiatry Laboratory,Bengaluru,Karnataka,India","institution_ids":["https://openalex.org/I699696"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065718043","display_name":"John P. John","orcid":"https://orcid.org/0000-0001-6756-0297"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"John P. John","raw_affiliation_strings":["Multimodal Brain Image Analysis Laboratory"],"affiliations":[{"raw_affiliation_string":"Multimodal Brain Image Analysis Laboratory","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033175043","display_name":"Jos\u00e9 Luis Ambite","orcid":"https://orcid.org/0000-0003-0087-080X"},"institutions":[{"id":"https://openalex.org/I4210111944","display_name":"Biomedical Research Institute of Southern California","ror":"https://ror.org/02a0gmf29","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210111944"]},{"id":"https://openalex.org/I903300897","display_name":"Southern States University","ror":"https://ror.org/01b0j0m34","country_code":"US","type":"education","lineage":["https://openalex.org/I903300897"]},{"id":"https://openalex.org/I2800817003","display_name":"Southern California University for Professional Studies","ror":"https://ror.org/058zz0t50","country_code":"US","type":"education","lineage":["https://openalex.org/I2800817003"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jose Luis Ambite","raw_affiliation_strings":["University of Southern California,Information Sciences Institute,CA,United States"],"affiliations":[{"raw_affiliation_string":"University of Southern California,Information Sciences Institute,CA,United States","institution_ids":["https://openalex.org/I4210111944","https://openalex.org/I2800817003","https://openalex.org/I903300897"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075920466","display_name":"Greg Ver Steeg","orcid":"https://orcid.org/0000-0002-0793-141X"},"institutions":[{"id":"https://openalex.org/I103635307","display_name":"University of California, Riverside","ror":"https://ror.org/03nawhv43","country_code":"US","type":"education","lineage":["https://openalex.org/I103635307"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Greg Ver Steeg","raw_affiliation_strings":["University of California,Riverside,CA,United States"],"affiliations":[{"raw_affiliation_string":"University of California,Riverside,CA,United States","institution_ids":["https://openalex.org/I103635307"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100606557","display_name":"Paul M. Thompson","orcid":"https://orcid.org/0000-0002-4720-8867"},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Paul M. Thompson","raw_affiliation_strings":["University of Southern California,Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine,CA,United States"],"affiliations":[{"raw_affiliation_string":"University of Southern California,Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine,CA,United States","institution_ids":["https://openalex.org/I1174212"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":9,"corresponding_author_ids":["https://openalex.org/A5074576951"],"corresponding_institution_ids":["https://openalex.org/I1174212"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.55153668,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"1","last_page":"4"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11304","display_name":"Advanced Neuroimaging Techniques and Applications","score":0.9642000198364258,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11304","display_name":"Advanced Neuroimaging Techniques and Applications","score":0.9642000198364258,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10241","display_name":"Functional Brain Connectivity Studies","score":0.023600000888109207,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12552","display_name":"Fetal and Pediatric Neurological Disorders","score":0.003000000026077032,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/diffusion-mri","display_name":"Diffusion MRI","score":0.7135999798774719},{"id":"https://openalex.org/keywords/synthetic-data","display_name":"Synthetic data","score":0.545799970626831},{"id":"https://openalex.org/keywords/neuroimaging","display_name":"Neuroimaging","score":0.51419997215271},{"id":"https://openalex.org/keywords/scalar","display_name":"Scalar (mathematics)","score":0.5120999813079834},{"id":"https://openalex.org/keywords/population","display_name":"Population","score":0.48899999260902405},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.4862000048160553},{"id":"https://openalex.org/keywords/generative-adversarial-network","display_name":"Generative adversarial network","score":0.44510000944137573},{"id":"https://openalex.org/keywords/translation","display_name":"Translation (biology)","score":0.4120999872684479},{"id":"https://openalex.org/keywords/prior-probability","display_name":"Prior probability","score":0.3939000070095062}],"concepts":[{"id":"https://openalex.org/C149550507","wikidata":"https://www.wikidata.org/wiki/Q899360","display_name":"Diffusion MRI","level":3,"score":0.7135999798774719},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.6230999827384949},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5820000171661377},{"id":"https://openalex.org/C160920958","wikidata":"https://www.wikidata.org/wiki/Q7662746","display_name":"Synthetic data","level":2,"score":0.545799970626831},{"id":"https://openalex.org/C58693492","wikidata":"https://www.wikidata.org/wiki/Q551875","display_name":"Neuroimaging","level":2,"score":0.51419997215271},{"id":"https://openalex.org/C57691317","wikidata":"https://www.wikidata.org/wiki/Q1289248","display_name":"Scalar (mathematics)","level":2,"score":0.5120999813079834},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.48899999260902405},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.4862000048160553},{"id":"https://openalex.org/C2988773926","wikidata":"https://www.wikidata.org/wiki/Q25104379","display_name":"Generative adversarial network","level":3,"score":0.44510000944137573},{"id":"https://openalex.org/C149364088","wikidata":"https://www.wikidata.org/wiki/Q185917","display_name":"Translation (biology)","level":4,"score":0.4120999872684479},{"id":"https://openalex.org/C177769412","wikidata":"https://www.wikidata.org/wiki/Q278090","display_name":"Prior probability","level":3,"score":0.3939000070095062},{"id":"https://openalex.org/C84787856","wikidata":"https://www.wikidata.org/wiki/Q3076659","display_name":"Tractography","level":4,"score":0.387800008058548},{"id":"https://openalex.org/C24756922","wikidata":"https://www.wikidata.org/wiki/Q1757694","display_name":"Data quality","level":3,"score":0.3718999922275543},{"id":"https://openalex.org/C39890363","wikidata":"https://www.wikidata.org/wiki/Q36108","display_name":"Generative grammar","level":2,"score":0.36230000853538513},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.34459999203681946},{"id":"https://openalex.org/C55020928","wikidata":"https://www.wikidata.org/wiki/Q3813865","display_name":"Image quality","level":3,"score":0.33469998836517334},{"id":"https://openalex.org/C99498987","wikidata":"https://www.wikidata.org/wiki/Q2210247","display_name":"Noise (video)","level":3,"score":0.3337000012397766},{"id":"https://openalex.org/C69357855","wikidata":"https://www.wikidata.org/wiki/Q163214","display_name":"Diffusion","level":2,"score":0.3188000023365021},{"id":"https://openalex.org/C2779530757","wikidata":"https://www.wikidata.org/wiki/Q1207505","display_name":"Quality (philosophy)","level":2,"score":0.3122999966144562},{"id":"https://openalex.org/C167966045","wikidata":"https://www.wikidata.org/wiki/Q5532625","display_name":"Generative model","level":3,"score":0.31200000643730164},{"id":"https://openalex.org/C155281189","wikidata":"https://www.wikidata.org/wiki/Q3518150","display_name":"Tensor (intrinsic definition)","level":2,"score":0.3109000027179718},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.29789999127388},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.296099990606308},{"id":"https://openalex.org/C9417928","wikidata":"https://www.wikidata.org/wiki/Q1070689","display_name":"Image processing","level":3,"score":0.28769999742507935},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.27720001339912415},{"id":"https://openalex.org/C36464697","wikidata":"https://www.wikidata.org/wiki/Q451553","display_name":"Visualization","level":2,"score":0.27480000257492065},{"id":"https://openalex.org/C37736160","wikidata":"https://www.wikidata.org/wiki/Q1801315","display_name":"Adversarial system","level":2,"score":0.26969999074935913},{"id":"https://openalex.org/C43521106","wikidata":"https://www.wikidata.org/wiki/Q2165493","display_name":"Pipeline (software)","level":2,"score":0.2639000117778778},{"id":"https://openalex.org/C55037315","wikidata":"https://www.wikidata.org/wiki/Q5421151","display_name":"Experimental data","level":2,"score":0.26109999418258667},{"id":"https://openalex.org/C108583219","wikidata":"https://www.wikidata.org/wiki/Q197536","display_name":"Deep learning","level":2,"score":0.25609999895095825},{"id":"https://openalex.org/C51632099","wikidata":"https://www.wikidata.org/wiki/Q3985153","display_name":"Training set","level":2,"score":0.25589999556541443}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/sipaim67325.2025.11283422","is_oa":false,"landing_page_url":"https://doi.org/10.1109/sipaim67325.2025.11283422","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2025 21st International Symposium on Biomedical Image Processing and Analysis (SIPAIM)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320337356","display_name":"Fogarty International Center","ror":"https://ror.org/02xey9a22"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":14,"referenced_works":["https://openalex.org/W1964802316","https://openalex.org/W2044904021","https://openalex.org/W2118347577","https://openalex.org/W2345496677","https://openalex.org/W2900856701","https://openalex.org/W2950336490","https://openalex.org/W2962793481","https://openalex.org/W2966232329","https://openalex.org/W2969676068","https://openalex.org/W3154981153","https://openalex.org/W4295434409","https://openalex.org/W4390194716","https://openalex.org/W4409316560","https://openalex.org/W4416960709"],"related_works":[],"abstract_inverted_index":{"Diffusion":[0],"tensor":[1],"imaging":[2],"(DTI)":[3],"provides":[4],"valuable":[5],"insights":[6],"into":[7],"brain":[8,45],"tissue":[9],"microstructure,":[10],"but":[11],"acquiring":[12],"high-quality":[13],"DTI":[14,35,100],"data":[15,24,118,134],"is":[16],"time-intensive":[17],"and":[18,26,75,87,98,110,120],"not":[19],"always":[20],"feasible.":[21],"To":[22],"mitigate":[23],"scarcity":[25],"enhance":[27],"accessibility,":[28],"we":[29],"investigate":[30],"the":[31,73,78],"generation":[32],"of":[33,77],"synthetic":[34,79,99],"scalar":[36],"maps\u2014specifically":[37],"mean":[38],"diffusivity":[39],"(MD)\u2014from":[40],"structural":[41],"3D":[42],"volumetric":[43],"T1-weighted":[44],"MRI":[46],"using":[47],"a":[48,63,137],"reversible":[49],"generative":[50],"adversarial":[51],"network":[52],"(RevGAN).":[53],"Unlike":[54],"conventional":[55],"pipelines":[56],"requiring":[57],"multiple":[58],"steps,":[59],"our":[60],"approach":[61],"enables":[62],"single-step":[64],"translation":[65],"from":[66,141],"T1":[67],"to":[68,136],"diffusion-derived":[69],"measures.":[70],"We":[71,125],"assess":[72],"quality":[74],"utility":[76],"maps":[80,101],"in":[81,122],"two":[82],"downstream":[83],"tasks:":[84],"sex":[85],"classification":[86],"Alzheimer's":[88],"disease":[89],"classification.":[90],"Performance":[91],"comparisons":[92],"between":[93],"models":[94,130],"trained":[95,131],"on":[96,132],"real":[97],"demonstrate":[102],"that":[103],"RevGAN-generated":[104],"images":[105],"retain":[106],"meaningful":[107],"microstructural":[108],"features":[109],"offer":[111],"competitive":[112],"accuracy,":[113],"underscoring":[114],"their":[115],"potential":[116],"for":[117],"augmentation":[119],"analysis":[121],"neuroimaging":[123],"workflows.":[124],"also":[126],"examine":[127],"how":[128],"well":[129],"these":[133],"generalize":[135],"new":[138],"population":[139],"dataset":[140],"India":[142],"(NIMHANS":[143],"cohort).":[144]},"counts_by_year":[],"updated_date":"2026-04-09T08:11:56.329763","created_date":"2025-12-18T00:00:00"}