{"id":"https://openalex.org/W7115889259","doi":"https://doi.org/10.1109/sipaim67325.2025.11283333","title":"Functional connectivity topology in EEG of Comatose Patients","display_name":"Functional connectivity topology in EEG of Comatose Patients","publication_year":2025,"publication_date":"2025-11-18","ids":{"openalex":"https://openalex.org/W7115889259","doi":"https://doi.org/10.1109/sipaim67325.2025.11283333"},"language":"en","primary_location":{"id":"doi:10.1109/sipaim67325.2025.11283333","is_oa":false,"landing_page_url":"https://doi.org/10.1109/sipaim67325.2025.11283333","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2025 21st International Symposium on Biomedical Image Processing and Analysis (SIPAIM)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Maria Camila Espinal","orcid":null},"institutions":[{"id":"https://openalex.org/I36243813","display_name":"Universidad Nacional de Colombia","ror":"https://ror.org/059yx9a68","country_code":"CO","type":"education","lineage":["https://openalex.org/I36243813"]}],"countries":["CO"],"is_corresponding":true,"raw_author_name":"Maria Camila Espinal","raw_affiliation_strings":["Universidad Nacional de Colombia,Departamento de Matemáticas,Bogotá,Colombia"],"affiliations":[{"raw_affiliation_string":"Universidad Nacional de Colombia,Departamento de Matemáticas,Bogotá,Colombia","institution_ids":["https://openalex.org/I36243813"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Steven Laureys","orcid":null},"institutions":[{"id":"https://openalex.org/I43406934","display_name":"Universit\u00e9 Laval","ror":"https://ror.org/04sjchr03","country_code":"CA","type":"education","lineage":["https://openalex.org/I43406934"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Steven Laureys","raw_affiliation_strings":["Université Laval,CERVO Brain Research Center,Canada"],"affiliations":[{"raw_affiliation_string":"Université Laval,CERVO Brain Research Center,Canada","institution_ids":["https://openalex.org/I43406934"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Michel van Putten","orcid":null},"institutions":[{"id":"https://openalex.org/I94624287","display_name":"University of Twente","ror":"https://ror.org/006hf6230","country_code":"NL","type":"education","lineage":["https://openalex.org/I94624287"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Michel van Putten","raw_affiliation_strings":["University of Twente,Clinical Neurophysiology,Enschede,Netherlands"],"affiliations":[{"raw_affiliation_string":"University of Twente,Clinical Neurophysiology,Enschede,Netherlands","institution_ids":["https://openalex.org/I94624287"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Jeannette Hofmeijer","orcid":null},"institutions":[{"id":"https://openalex.org/I94624287","display_name":"University of Twente","ror":"https://ror.org/006hf6230","country_code":"NL","type":"education","lineage":["https://openalex.org/I94624287"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Jeannette Hofmeijer","raw_affiliation_strings":["University of Twente,Clinical Neurophysiology,Enschede,Netherlands"],"affiliations":[{"raw_affiliation_string":"University of Twente,Clinical Neurophysiology,Enschede,Netherlands","institution_ids":["https://openalex.org/I94624287"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Francisco G\u00f3mez","orcid":null},"institutions":[{"id":"https://openalex.org/I36243813","display_name":"Universidad Nacional de Colombia","ror":"https://ror.org/059yx9a68","country_code":"CO","type":"education","lineage":["https://openalex.org/I36243813"]}],"countries":["CO"],"is_corresponding":false,"raw_author_name":"Francisco G\u00f3mez","raw_affiliation_strings":["Universidad Nacional de Colombia,Departamento de Matemáticas,Bogotá,Colombia"],"affiliations":[{"raw_affiliation_string":"Universidad Nacional de Colombia,Departamento de Matemáticas,Bogotá,Colombia","institution_ids":["https://openalex.org/I36243813"]}]},{"author_position":"last","author":{"id":null,"display_name":"Prejaas Kavish Baldewpersad Tewarie","orcid":null},"institutions":[{"id":"https://openalex.org/I43406934","display_name":"Universit\u00e9 Laval","ror":"https://ror.org/04sjchr03","country_code":"CA","type":"education","lineage":["https://openalex.org/I43406934"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Prejaas Kavish Baldewpersad Tewarie","raw_affiliation_strings":["Université Laval,CERVO Brain Research Center,Canada"],"affiliations":[{"raw_affiliation_string":"Université Laval,CERVO Brain Research Center,Canada","institution_ids":["https://openalex.org/I43406934"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":6,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I36243813"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.64301166,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"1","last_page":"4"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10241","display_name":"Functional Brain Connectivity Studies","score":0.7839000225067139,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10241","display_name":"Functional Brain Connectivity Studies","score":0.7839000225067139,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12536","display_name":"Topological and Geometric Data Analysis","score":0.0989999994635582,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10416","display_name":"Traumatic Brain Injury Research","score":0.03139999881386757,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/electroencephalography","display_name":"Electroencephalography","score":0.756600022315979},{"id":"https://openalex.org/keywords/functional-connectivity","display_name":"Functional connectivity","score":0.6988999843597412},{"id":"https://openalex.org/keywords/coma","display_name":"Coma (optics)","score":0.6930999755859375},{"id":"https://openalex.org/keywords/network-topology","display_name":"Network topology","score":0.5965999960899353},{"id":"https://openalex.org/keywords/topology","display_name":"Topology (electrical circuits)","score":0.5339000225067139},{"id":"https://openalex.org/keywords/synchronization","display_name":"Synchronization (alternating current)","score":0.44040000438690186},{"id":"https://openalex.org/keywords/topological-data-analysis","display_name":"Topological data analysis","score":0.41290000081062317},{"id":"https://openalex.org/keywords/neurophysiology","display_name":"Neurophysiology","score":0.3422999978065491}],"concepts":[{"id":"https://openalex.org/C522805319","wikidata":"https://www.wikidata.org/wiki/Q179965","display_name":"Electroencephalography","level":2,"score":0.756600022315979},{"id":"https://openalex.org/C3018011982","wikidata":"https://www.wikidata.org/wiki/Q7316120","display_name":"Functional connectivity","level":2,"score":0.6988999843597412},{"id":"https://openalex.org/C100136789","wikidata":"https://www.wikidata.org/wiki/Q1772448","display_name":"Coma (optics)","level":2,"score":0.6930999755859375},{"id":"https://openalex.org/C199845137","wikidata":"https://www.wikidata.org/wiki/Q145490","display_name":"Network topology","level":2,"score":0.5965999960899353},{"id":"https://openalex.org/C184720557","wikidata":"https://www.wikidata.org/wiki/Q7825049","display_name":"Topology (electrical circuits)","level":2,"score":0.5339000225067139},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.52920001745224},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.506600022315979},{"id":"https://openalex.org/C2778562939","wikidata":"https://www.wikidata.org/wiki/Q1298791","display_name":"Synchronization (alternating current)","level":3,"score":0.44040000438690186},{"id":"https://openalex.org/C2776477805","wikidata":"https://www.wikidata.org/wiki/Q4460773","display_name":"Topological data analysis","level":2,"score":0.41290000081062317},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3531000018119812},{"id":"https://openalex.org/C152478114","wikidata":"https://www.wikidata.org/wiki/Q660910","display_name":"Neurophysiology","level":2,"score":0.3422999978065491},{"id":"https://openalex.org/C3018390542","wikidata":"https://www.wikidata.org/wiki/Q1073","display_name":"Brain function","level":2,"score":0.32019999623298645},{"id":"https://openalex.org/C50644808","wikidata":"https://www.wikidata.org/wiki/Q192776","display_name":"Artificial neural network","level":2,"score":0.31540000438690186},{"id":"https://openalex.org/C2780196419","wikidata":"https://www.wikidata.org/wiki/Q1762173","display_name":"Nerve net","level":2,"score":0.305400013923645},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.3001999855041504},{"id":"https://openalex.org/C32946077","wikidata":"https://www.wikidata.org/wiki/Q618079","display_name":"Network analysis","level":2,"score":0.29269999265670776},{"id":"https://openalex.org/C50231774","wikidata":"https://www.wikidata.org/wiki/Q639842","display_name":"Brain mapping","level":2,"score":0.2867000102996826},{"id":"https://openalex.org/C125990524","wikidata":"https://www.wikidata.org/wiki/Q5322921","display_name":"EEG-fMRI","level":3,"score":0.27410000562667847},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.2734000086784363},{"id":"https://openalex.org/C2777670902","wikidata":"https://www.wikidata.org/wiki/Q492038","display_name":"Human brain","level":2,"score":0.27140000462532043},{"id":"https://openalex.org/C120843803","wikidata":"https://www.wikidata.org/wiki/Q4955807","display_name":"Brain activity and meditation","level":3,"score":0.26460000872612},{"id":"https://openalex.org/C2781017439","wikidata":"https://www.wikidata.org/wiki/Q1995526","display_name":"Traumatic brain injury","level":2,"score":0.257999986410141},{"id":"https://openalex.org/C2780385302","wikidata":"https://www.wikidata.org/wiki/Q367158","display_name":"Protocol (science)","level":3,"score":0.25440001487731934}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1109/sipaim67325.2025.11283333","is_oa":false,"landing_page_url":"https://doi.org/10.1109/sipaim67325.2025.11283333","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2025 21st International Symposium on Biomedical Image Processing and Analysis (SIPAIM)","raw_type":"proceedings-article"},{"id":"pmh:oai:ris.utwente.nl:publications/3da5568c-3040-440a-9321-7a21b578c018","is_oa":false,"landing_page_url":"https://research.utwente.nl/en/publications/3da5568c-3040-440a-9321-7a21b578c018","pdf_url":null,"source":{"id":"https://openalex.org/S4406922991","display_name":"University of Twente Research Information","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Espinal, M C, Laureys, S, van Putten, M, Hofmeijer, J, G\u00f3mez, F & Baldewpersad Tewarie, P K 2025, Functional connectivity topology in EEG of Comatose Patients. in Proceedings of the 21st International Symposium on Biomedical Information Processing and Analysis, SIPAIM 2025. International Symposium on Biomedical Information Processing and Analysis (SIPAIM), vol. 2025, IEEE, 21st International Symposium on Medical Information Processing and Analysis, SIPAIM 2025, Pasto, Colombia, 19/11/25. https://doi.org/10.1109/SIPAIM67325.2025.11283333","raw_type":"info:eu-repo/semantics/publishedVersion"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/1","display_name":"No poverty","score":0.4195394814014435}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":16,"referenced_works":["https://openalex.org/W2021285908","https://openalex.org/W2123261069","https://openalex.org/W2127000432","https://openalex.org/W2167822639","https://openalex.org/W2340630205","https://openalex.org/W2553157470","https://openalex.org/W2768955764","https://openalex.org/W2921083718","https://openalex.org/W2950121576","https://openalex.org/W2962849396","https://openalex.org/W3085509199","https://openalex.org/W3192873986","https://openalex.org/W4298005481","https://openalex.org/W4311200874","https://openalex.org/W4362663587","https://openalex.org/W4388895596"],"related_works":[],"abstract_inverted_index":{"Post-cardiac":[0],"arrest":[1,8],"coma,":[2],"is":[3,38],"a":[4,83,98],"consequence":[5],"of":[6,23,33,95],"post-cardiac":[7],"anoxic":[9],"brain":[10,34,102],"injury":[11],"(PCABI)":[12],"that":[13,68,82],"significantly":[14],"impacts":[15],"patient":[16],"survival,":[17],"with":[18,47,70],"neurological":[19],"prognosis":[20],"guiding":[21],"withdrawal":[22],"life-sustaining":[24],"therapy":[25],"(WLST).":[26],"Continuous":[27],"electroencephalography":[28],"(EEG)":[29],"facilitates":[30],"real-time":[31],"monitoring":[32],"activity.":[35],"However,":[36],"there":[37],"no":[39],"consensus":[40],"on":[41],"which":[42],"EEG-based":[43],"patterns":[44],"may":[45,86],"link":[46],"recovery":[48],"or":[49],"deterioration.":[50],"In":[51],"this":[52],"study,":[53],"we":[54],"applied":[55],"Topological":[56],"Data":[57],"Analysis":[58],"(TDA)":[59],"to":[60,89],"analyze":[61],"EEG-derived":[62],"functional":[63],"connectivity":[64],"(FC)":[65],"networks,":[66],"revealing":[67],"patients":[69],"poor":[71],"outcomes":[72],"exhibit":[73],"higher":[74],"network":[75,84,103],"density":[76],"and":[77],"efficiency.":[78],"These":[79],"findings":[80],"suggest":[81],"reorganization":[85],"be":[87],"linked":[88],"worse":[90],"prognoses,":[91],"highlighting":[92],"the":[93],"potential":[94],"TDA":[96],"as":[97],"complementary":[99],"approach":[100],"for":[101],"characterization":[104],"in":[105],"coma":[106],"assessment.":[107]},"counts_by_year":[],"updated_date":"2026-04-10T15:06:20.359241","created_date":"2025-12-19T00:00:00"}