{"id":"https://openalex.org/W4405490758","doi":"https://doi.org/10.1109/sensors60989.2024.10784910","title":"A Quantitative Microfluidic Flow Cytometer Based on Spaced Uniform Optical Fields","display_name":"A Quantitative Microfluidic Flow Cytometer Based on Spaced Uniform Optical Fields","publication_year":2024,"publication_date":"2024-10-20","ids":{"openalex":"https://openalex.org/W4405490758","doi":"https://doi.org/10.1109/sensors60989.2024.10784910"},"language":"en","primary_location":{"id":"doi:10.1109/sensors60989.2024.10784910","is_oa":false,"landing_page_url":"https://doi.org/10.1109/sensors60989.2024.10784910","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2024 IEEE SENSORS","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5045806923","display_name":"Chiyuan Gao","orcid":null},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210107198","display_name":"State Key Laboratory of Transducer Technology","ror":"https://ror.org/01qg56n75","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366","https://openalex.org/I19820366","https://openalex.org/I4210107198","https://openalex.org/I4210110458","https://openalex.org/I4210147322"]},{"id":"https://openalex.org/I4210137199","display_name":"Aerospace Information Research Institute","ror":"https://ror.org/0419fj215","country_code":"CN","type":"education","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210137199"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chiyuan Gao","raw_affiliation_strings":["Aerospace Information Research Institute, Chinese Academy of Sciences,State Key Laboratory of Transducer Technology,Beijing,China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Aerospace Information Research Institute, Chinese Academy of Sciences,State Key Laboratory of Transducer Technology,Beijing,China","institution_ids":["https://openalex.org/I4210107198","https://openalex.org/I19820366","https://openalex.org/I4210137199"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103855170","display_name":"Long Fan","orcid":null},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210107198","display_name":"State Key Laboratory of Transducer Technology","ror":"https://ror.org/01qg56n75","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366","https://openalex.org/I19820366","https://openalex.org/I4210107198","https://openalex.org/I4210110458","https://openalex.org/I4210147322"]},{"id":"https://openalex.org/I4210137199","display_name":"Aerospace Information Research Institute","ror":"https://ror.org/0419fj215","country_code":"CN","type":"education","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210137199"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Long Fan","raw_affiliation_strings":["Aerospace Information Research Institute, Chinese Academy of Sciences,State Key Laboratory of Transducer Technology,Beijing,China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Aerospace Information Research Institute, Chinese Academy of Sciences,State Key Laboratory of Transducer Technology,Beijing,China","institution_ids":["https://openalex.org/I4210107198","https://openalex.org/I19820366","https://openalex.org/I4210137199"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090100242","display_name":"Guang Yang","orcid":"https://orcid.org/0000-0002-8430-6917"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210107198","display_name":"State Key Laboratory of Transducer Technology","ror":"https://ror.org/01qg56n75","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366","https://openalex.org/I19820366","https://openalex.org/I4210107198","https://openalex.org/I4210110458","https://openalex.org/I4210147322"]},{"id":"https://openalex.org/I4210137199","display_name":"Aerospace Information Research Institute","ror":"https://ror.org/0419fj215","country_code":"CN","type":"education","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210137199"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Guang Yang","raw_affiliation_strings":["Aerospace Information Research Institute, Chinese Academy of Sciences,State Key Laboratory of Transducer Technology,Beijing,China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Aerospace Information Research Institute, Chinese Academy of Sciences,State Key Laboratory of Transducer Technology,Beijing,China","institution_ids":["https://openalex.org/I4210107198","https://openalex.org/I19820366","https://openalex.org/I4210137199"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109218676","display_name":"Junbo Wang","orcid":"https://orcid.org/0000-0002-6032-1274"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210107198","display_name":"State Key Laboratory of Transducer Technology","ror":"https://ror.org/01qg56n75","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366","https://openalex.org/I19820366","https://openalex.org/I4210107198","https://openalex.org/I4210110458","https://openalex.org/I4210147322"]},{"id":"https://openalex.org/I4210137199","display_name":"Aerospace Information Research Institute","ror":"https://ror.org/0419fj215","country_code":"CN","type":"education","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210137199"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Junbo Wang","raw_affiliation_strings":["Aerospace Information Research Institute, Chinese Academy of Sciences,State Key Laboratory of Transducer Technology,Beijing,China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Aerospace Information Research Institute, Chinese Academy of Sciences,State Key Laboratory of Transducer Technology,Beijing,China","institution_ids":["https://openalex.org/I4210107198","https://openalex.org/I19820366","https://openalex.org/I4210137199"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Xiaosu Zhao","orcid":null},"institutions":[{"id":"https://openalex.org/I20231570","display_name":"Peking University","ror":"https://ror.org/02v51f717","country_code":"CN","type":"education","lineage":["https://openalex.org/I20231570"]},{"id":"https://openalex.org/I4210124809","display_name":"Peking University People's Hospital","ror":"https://ror.org/035adwg89","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210124809"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaosu Zhao","raw_affiliation_strings":["Peking University People's Hospital, Peking University Institute of Hematology, National Clinical Research Center for Hematologic Disease,Beijing Key Laboratory of Hematopoietic Stem Cell Transplantation,Beijing,China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Peking University People's Hospital, Peking University Institute of Hematology, National Clinical Research Center for Hematologic Disease,Beijing Key Laboratory of Hematopoietic Stem Cell Transplantation,Beijing,China","institution_ids":["https://openalex.org/I4210124809","https://openalex.org/I20231570"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003388916","display_name":"Xiaoye Huo","orcid":"https://orcid.org/0000-0001-8309-8637"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210107198","display_name":"State Key Laboratory of Transducer Technology","ror":"https://ror.org/01qg56n75","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366","https://openalex.org/I19820366","https://openalex.org/I4210107198","https://openalex.org/I4210110458","https://openalex.org/I4210147322"]},{"id":"https://openalex.org/I4210137199","display_name":"Aerospace Information Research Institute","ror":"https://ror.org/0419fj215","country_code":"CN","type":"education","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210137199"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaoye Huo","raw_affiliation_strings":["Aerospace Information Research Institute, Chinese Academy of Sciences,State Key Laboratory of Transducer Technology,Beijing,China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Aerospace Information Research Institute, Chinese Academy of Sciences,State Key Laboratory of Transducer Technology,Beijing,China","institution_ids":["https://openalex.org/I4210107198","https://openalex.org/I19820366","https://openalex.org/I4210137199"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100326500","display_name":"Jian Chen","orcid":"https://orcid.org/0000-0003-4612-3279"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210107198","display_name":"State Key Laboratory of Transducer Technology","ror":"https://ror.org/01qg56n75","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366","https://openalex.org/I19820366","https://openalex.org/I4210107198","https://openalex.org/I4210110458","https://openalex.org/I4210147322"]},{"id":"https://openalex.org/I4210137199","display_name":"Aerospace Information Research Institute","ror":"https://ror.org/0419fj215","country_code":"CN","type":"education","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210137199"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jian Chen","raw_affiliation_strings":["Aerospace Information Research Institute, Chinese Academy of Sciences,State Key Laboratory of Transducer Technology,Beijing,China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Aerospace Information Research Institute, Chinese Academy of Sciences,State Key Laboratory of Transducer Technology,Beijing,China","institution_ids":["https://openalex.org/I4210107198","https://openalex.org/I19820366","https://openalex.org/I4210137199"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.20416819,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"1","last_page":"4"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11255","display_name":"Microfluidic and Bio-sensing Technologies","score":0.987500011920929,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11255","display_name":"Microfluidic and Bio-sensing Technologies","score":0.987500011920929,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12537","display_name":"Flow Measurement and Analysis","score":0.9314000010490417,"subfield":{"id":"https://openalex.org/subfields/2211","display_name":"Mechanics of Materials"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12141","display_name":"Fluid Dynamics and Thin Films","score":0.901199996471405,"subfield":{"id":"https://openalex.org/subfields/2206","display_name":"Computational Mechanics"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/microfluidics","display_name":"Microfluidics","score":0.8309897184371948},{"id":"https://openalex.org/keywords/flow","display_name":"Flow (mathematics)","score":0.5671564340591431},{"id":"https://openalex.org/keywords/optical-flow","display_name":"Optical flow","score":0.4314054548740387},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.42659521102905273},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.36441367864608765},{"id":"https://openalex.org/keywords/mechanics","display_name":"Mechanics","score":0.2126481533050537},{"id":"https://openalex.org/keywords/nanotechnology","display_name":"Nanotechnology","score":0.21094071865081787},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.2101946473121643},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.12414121627807617}],"concepts":[{"id":"https://openalex.org/C8673954","wikidata":"https://www.wikidata.org/wiki/Q138845","display_name":"Microfluidics","level":2,"score":0.8309897184371948},{"id":"https://openalex.org/C38349280","wikidata":"https://www.wikidata.org/wiki/Q1434290","display_name":"Flow (mathematics)","level":2,"score":0.5671564340591431},{"id":"https://openalex.org/C155542232","wikidata":"https://www.wikidata.org/wiki/Q736111","display_name":"Optical flow","level":3,"score":0.4314054548740387},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.42659521102905273},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.36441367864608765},{"id":"https://openalex.org/C57879066","wikidata":"https://www.wikidata.org/wiki/Q41217","display_name":"Mechanics","level":1,"score":0.2126481533050537},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.21094071865081787},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.2101946473121643},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.12414121627807617},{"id":"https://openalex.org/C115961682","wikidata":"https://www.wikidata.org/wiki/Q860623","display_name":"Image (mathematics)","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/sensors60989.2024.10784910","is_oa":false,"landing_page_url":"https://doi.org/10.1109/sensors60989.2024.10784910","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2024 IEEE SENSORS","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G35275448","display_name":null,"funder_award_id":"62331025,62121003","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":7,"referenced_works":["https://openalex.org/W2741289900","https://openalex.org/W3080696612","https://openalex.org/W3164112103","https://openalex.org/W3166286726","https://openalex.org/W3200649415","https://openalex.org/W4309745559","https://openalex.org/W4386020081"],"related_works":["https://openalex.org/W4391375266","https://openalex.org/W2899084033","https://openalex.org/W2748952813","https://openalex.org/W4404995717","https://openalex.org/W2016187641","https://openalex.org/W4404725684","https://openalex.org/W2805339068","https://openalex.org/W4246450666","https://openalex.org/W4388998267","https://openalex.org/W2898370298"],"abstract_inverted_index":{"This":[0],"study":[1],"presented":[2],"a":[3,131],"quantitative":[4,115,138],"microfluidic":[5,126],"flow":[6,127],"cytometer":[7],"based":[8,113],"on":[9,76,114],"spaced":[10,61],"uniform":[11,33,42,62,72],"optical":[12,19,34,63],"fields,":[13],"which":[14],"were":[15,84,107,119],"constructed":[16],"by":[17,109],"adopting":[18],"paths":[20],"of":[21,46,59,81,92,103,137],"conventional":[22],"microscopy.":[23],"Single":[24],"cells":[25],"with":[26,48,67,87],"stained":[27],"fluorescent":[28,101],"probes":[29],"travel":[30],"through":[31],"three":[32],"spots":[35],"sequentially":[36],"and":[37,71,112],"leveraging":[38],"calibration":[39,79,105],"solutions":[40],"under":[41],"excitation,":[43],"nine":[44],"types":[45],"proteins":[47],"arbitrary":[49],"distributions":[50,73],"at":[51,97],"the":[52,60,88,135],"single-cell":[53,139],"level":[54],"can":[55],"be":[56],"quantified.":[57],"Characterization":[58],"fields":[64],"was":[65],"conducted":[66],"corresponding":[68],"geometrical":[69],"parameters":[70],"confirmed.":[74],"Based":[75],"this":[77,110],"approach,":[78],"curves":[80],"nine-fluorescence":[82],"channels":[83],"linearly":[85],"correlated":[86],"best":[89],"detection":[90],"limit":[91],"10":[93],"molecule":[94],"per":[95],"cell":[96],"PE":[98],"channel.":[99],"Five-channel":[100],"signals":[102],"rainbow":[104],"microbeads":[106,118],"sampled":[108],"platform":[111],"results":[116],"these":[117],"classified":[120],"into":[121],"six":[122],"subtypes.":[123],"The":[124],"developed":[125],"cytometry":[128],"may":[129],"provide":[130],"new":[132],"perspective":[133],"in":[134],"field":[136],"protein":[140],"analysis.":[141]},"counts_by_year":[],"updated_date":"2026-06-11T09:08:48.828518","created_date":"2025-10-10T00:00:00"}