{"id":"https://openalex.org/W4389101805","doi":"https://doi.org/10.1109/sensors56945.2023.10324998","title":"Evaluating Orthostatic Responses with Wearable Chest-Based Photoplethysmography in Patients with Parkinson's Disease","display_name":"Evaluating Orthostatic Responses with Wearable Chest-Based Photoplethysmography in Patients with Parkinson's Disease","publication_year":2023,"publication_date":"2023-10-29","ids":{"openalex":"https://openalex.org/W4389101805","doi":"https://doi.org/10.1109/sensors56945.2023.10324998"},"language":"en","primary_location":{"id":"doi:10.1109/sensors56945.2023.10324998","is_oa":false,"landing_page_url":"https://doi.org/10.1109/sensors56945.2023.10324998","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2023 IEEE SENSORS","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5102932398","display_name":"John A. Berkebile","orcid":"https://orcid.org/0000-0003-0263-7083"},"institutions":[{"id":"https://openalex.org/I130701444","display_name":"Georgia Institute of Technology","ror":"https://ror.org/01zkghx44","country_code":"US","type":"education","lineage":["https://openalex.org/I130701444"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"John A. Berkebile","raw_affiliation_strings":["School of Electrical and Computer Engineering, Georgia Institute of Technology,Atlanta,GA,USA","School of Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, GA, USA"],"affiliations":[{"raw_affiliation_string":"School of Electrical and Computer Engineering, Georgia Institute of Technology,Atlanta,GA,USA","institution_ids":["https://openalex.org/I130701444"]},{"raw_affiliation_string":"School of Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, GA, USA","institution_ids":["https://openalex.org/I130701444"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076927036","display_name":"Omer T. Inan","orcid":"https://orcid.org/0000-0002-7952-1794"},"institutions":[{"id":"https://openalex.org/I130701444","display_name":"Georgia Institute of Technology","ror":"https://ror.org/01zkghx44","country_code":"US","type":"education","lineage":["https://openalex.org/I130701444"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Omer T. Inan","raw_affiliation_strings":["School of Electrical and Computer Engineering, Georgia Institute of Technology,Atlanta,GA,USA","School of Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, GA, USA"],"affiliations":[{"raw_affiliation_string":"School of Electrical and Computer Engineering, Georgia Institute of Technology,Atlanta,GA,USA","institution_ids":["https://openalex.org/I130701444"]},{"raw_affiliation_string":"School of Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, GA, USA","institution_ids":["https://openalex.org/I130701444"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5037692919","display_name":"Paul A. Beach","orcid":"https://orcid.org/0000-0002-3657-7106"},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Paul A. Beach","raw_affiliation_strings":["Emory University, School of Medicine,Department of Neurology,Atlanta,GA,USA","Department of Neurology, Emory University, School of Medicine, Atlanta, GA, USA"],"affiliations":[{"raw_affiliation_string":"Emory University, School of Medicine,Department of Neurology,Atlanta,GA,USA","institution_ids":["https://openalex.org/I150468666"]},{"raw_affiliation_string":"Department of Neurology, Emory University, School of Medicine, Atlanta, GA, USA","institution_ids":["https://openalex.org/I150468666"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5102932398"],"corresponding_institution_ids":["https://openalex.org/I130701444"],"apc_list":null,"apc_paid":null,"fwci":1.8909,"has_fulltext":false,"cited_by_count":6,"citation_normalized_percentile":{"value":0.86232234,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":97,"max":99},"biblio":{"volume":null,"issue":null,"first_page":"1","last_page":"4"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11950","display_name":"Cardiovascular Syncope and Autonomic Disorders","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11950","display_name":"Cardiovascular Syncope and Autonomic Disorders","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10745","display_name":"Heart Rate Variability and Autonomic Control","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11196","display_name":"Non-Invasive Vital Sign Monitoring","score":0.9987999796867371,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/photoplethysmogram","display_name":"Photoplethysmogram","score":0.7764914035797119},{"id":"https://openalex.org/keywords/orthostatic-vital-signs","display_name":"Orthostatic vital signs","score":0.6829531788825989},{"id":"https://openalex.org/keywords/baroreflex","display_name":"Baroreflex","score":0.6100367903709412},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.5764141082763672},{"id":"https://openalex.org/keywords/blood-pressure","display_name":"Blood pressure","score":0.5355315804481506},{"id":"https://openalex.org/keywords/cardiology","display_name":"Cardiology","score":0.4841950237751007},{"id":"https://openalex.org/keywords/pure-autonomic-failure","display_name":"Pure autonomic failure","score":0.4613390862941742},{"id":"https://openalex.org/keywords/parkinsons-disease","display_name":"Parkinson's disease","score":0.4598338305950165},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.4339648485183716},{"id":"https://openalex.org/keywords/supine-position","display_name":"Supine position","score":0.4324406683444977},{"id":"https://openalex.org/keywords/orthostatic-intolerance","display_name":"Orthostatic intolerance","score":0.4188735783100128},{"id":"https://openalex.org/keywords/heart-rate","display_name":"Heart rate","score":0.3585307002067566},{"id":"https://openalex.org/keywords/disease","display_name":"Disease","score":0.26949378848075867},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.16260051727294922}],"concepts":[{"id":"https://openalex.org/C116390426","wikidata":"https://www.wikidata.org/wiki/Q7187885","display_name":"Photoplethysmogram","level":3,"score":0.7764914035797119},{"id":"https://openalex.org/C73787029","wikidata":"https://www.wikidata.org/wiki/Q7104929","display_name":"Orthostatic vital signs","level":3,"score":0.6829531788825989},{"id":"https://openalex.org/C191237925","wikidata":"https://www.wikidata.org/wiki/Q808725","display_name":"Baroreflex","level":4,"score":0.6100367903709412},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5764141082763672},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.5355315804481506},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.4841950237751007},{"id":"https://openalex.org/C2781177144","wikidata":"https://www.wikidata.org/wiki/Q896883","display_name":"Pure autonomic failure","level":4,"score":0.4613390862941742},{"id":"https://openalex.org/C2779734285","wikidata":"https://www.wikidata.org/wiki/Q11085","display_name":"Parkinson's disease","level":3,"score":0.4598338305950165},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4339648485183716},{"id":"https://openalex.org/C125567185","wikidata":"https://www.wikidata.org/wiki/Q3267428","display_name":"Supine position","level":2,"score":0.4324406683444977},{"id":"https://openalex.org/C2779624417","wikidata":"https://www.wikidata.org/wiki/Q7104932","display_name":"Orthostatic intolerance","level":4,"score":0.4188735783100128},{"id":"https://openalex.org/C2777953023","wikidata":"https://www.wikidata.org/wiki/Q1073121","display_name":"Heart rate","level":3,"score":0.3585307002067566},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.26949378848075867},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.16260051727294922},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.0},{"id":"https://openalex.org/C106131492","wikidata":"https://www.wikidata.org/wiki/Q3072260","display_name":"Filter (signal processing)","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/sensors56945.2023.10324998","is_oa":false,"landing_page_url":"https://doi.org/10.1109/sensors56945.2023.10324998","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2023 IEEE SENSORS","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/10","score":0.7200000286102295,"display_name":"Reduced inequalities"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320308987","display_name":"American Parkinson Disease Association","ror":"https://ror.org/04sedwh45"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":24,"referenced_works":["https://openalex.org/W1970748183","https://openalex.org/W1986205211","https://openalex.org/W2013608425","https://openalex.org/W2046012313","https://openalex.org/W2046969478","https://openalex.org/W2064996887","https://openalex.org/W2072858761","https://openalex.org/W2090630960","https://openalex.org/W2093664273","https://openalex.org/W2121381105","https://openalex.org/W2128337788","https://openalex.org/W2137626905","https://openalex.org/W2162273778","https://openalex.org/W2236428329","https://openalex.org/W2415864013","https://openalex.org/W2518704184","https://openalex.org/W2781877724","https://openalex.org/W2966254614","https://openalex.org/W3045506621","https://openalex.org/W3127637041","https://openalex.org/W4200045975","https://openalex.org/W4200165088","https://openalex.org/W4200218873","https://openalex.org/W4320498737"],"related_works":["https://openalex.org/W2977563813","https://openalex.org/W2054446466","https://openalex.org/W2468846348","https://openalex.org/W2085684421","https://openalex.org/W1992623300","https://openalex.org/W2562798986","https://openalex.org/W2027693100","https://openalex.org/W2163860634","https://openalex.org/W157090944","https://openalex.org/W2117557507"],"abstract_inverted_index":{"Orthostatic":[0],"hypotension":[1],"(OH)":[2],"is":[3,22,168],"a":[4,32,58,94,169],"hallmark":[5],"manifestation":[6],"of":[7,52,74,173,180,191],"cardiovascular":[8,43,65,192],"autonomic":[9,44,193],"dysfunction":[10],"in":[11,20,31,35,46,124,136,153],"Parkinson's":[12],"disease":[13],"(PD).":[14],"Following":[15],"an":[16,90],"orthostatic":[17,91,159],"stressor,":[18],"OH":[19,174,181],"PD":[21,81,131],"characterized":[23],"by":[24],"impaired":[25],"baroreflex":[26],"and":[27,61,72,100,175,187],"vasomotor":[28],"function,":[29],"resulting":[30],"pathological":[33],"fall":[34],"blood":[36],"pressure":[37,155],"(BP).":[38],"The":[39],"morbidity":[40],"associated":[41],"with":[42,48,80,87],"dysfunction,":[45],"conjunction":[47],"the":[49,125,130,134,151,158],"current":[50],"limitations":[51],"methods":[53],"for":[54,69,184],"assessing":[55],"OH,":[56],"presents":[57],"challenging":[59],"clinical":[60],"technological":[62],"problem.":[63],"Wearable":[64],"sensing":[66],"holds":[67],"promise":[68],"improving":[70],"detection":[71,179],"management":[73,190],"OH.":[75],"In":[76],"this":[77],"study,":[78],"participants":[79],"(":[82,117,142],"<tex":[83,118,143],"xmlns:mml=\"http://www.w3.org/1998/Math/MathML\"":[84,119,144],"xmlns:xlink=\"http://www.w3.org/1999/xlink\">$\\mathrm{n}=6,":[85],"3$</tex>":[86],"OH)":[88],"underwent":[89],"challenge":[92],"wearing":[93],"chest":[95],"patch":[96],"capturing":[97],"electrocardiogram":[98],"(ECG)":[99],"photoplethysmogram":[101],"(PPG)":[102],"signals":[103],"alongside":[104],"reference":[105],"beat-to-beat":[106],"BP.":[107],"From":[108],"supine":[109],"to":[110,129,150],"standing,":[111],"PPG":[112,137,166],"amplitude":[113,138,167],"decreased":[114],"significantly":[115,140],"more":[116,188],"xmlns:xlink=\"http://www.w3.org/1999/xlink\">$\\mathrm{p}":[120],"&lt;":[121,147],"0.05$</tex>":[122,148],")":[123,149],"PD+OH":[126],"group":[127],"compared":[128],"group.":[132],"Further,":[133],"change":[135,152],"was":[139],"correlated":[141],"xmlns:xlink=\"http://www.w3.org/1999/xlink\">$\\mathrm{r}=0.83,\\":[145],"\\mathrm{p}":[146],"pulse":[154],"(PP)":[156],"during":[157],"challenge.":[160],"These":[161],"findings":[162],"suggest":[163],"that":[164],"sternal":[165],"potential":[170],"discriminative":[171],"marker":[172],"may":[176],"enable":[177],"noninvasive":[178],"episodes,":[182],"allowing":[183],"earlier":[185],"diagnoses":[186],"optimal":[189],"health.":[194]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":4}],"updated_date":"2026-04-06T07:47:59.780226","created_date":"2025-10-10T00:00:00"}
