{"id":"https://openalex.org/W7131618788","doi":"https://doi.org/10.1109/rif68108.2025.11406871","title":"Machine Learning Solution for Drug Dosage and Anomaly Correction in Nanorobot Cancer Therapy","display_name":"Machine Learning Solution for Drug Dosage and Anomaly Correction in Nanorobot Cancer Therapy","publication_year":2025,"publication_date":"2025-12-08","ids":{"openalex":"https://openalex.org/W7131618788","doi":"https://doi.org/10.1109/rif68108.2025.11406871"},"language":null,"primary_location":{"id":"doi:10.1109/rif68108.2025.11406871","is_oa":false,"landing_page_url":"https://doi.org/10.1109/rif68108.2025.11406871","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2025 International Conference on Research in Computing at Feminine (RIF)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5126868867","display_name":"Rayene Meghlaoui","orcid":null},"institutions":[{"id":"https://openalex.org/I4210160465","display_name":"Universit\u00e9 Constantine 2","ror":"https://ror.org/056mctw68","country_code":"DZ","type":"education","lineage":["https://openalex.org/I4210160465"]}],"countries":["DZ"],"is_corresponding":false,"raw_author_name":"Rayene Meghlaoui","raw_affiliation_strings":["University of Constantine 2 - Abdelhamid Mehri,LISIA Laboratory Faculty of NTIC,Constantine,Algeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Constantine 2 - Abdelhamid Mehri,LISIA Laboratory Faculty of NTIC,Constantine,Algeria","institution_ids":["https://openalex.org/I4210160465"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5126854614","display_name":"Rostom Mennour","orcid":null},"institutions":[{"id":"https://openalex.org/I4210160465","display_name":"Universit\u00e9 Constantine 2","ror":"https://ror.org/056mctw68","country_code":"DZ","type":"education","lineage":["https://openalex.org/I4210160465"]}],"countries":["DZ"],"is_corresponding":false,"raw_author_name":"Rostom Mennour","raw_affiliation_strings":["University of Constantine 2 - Abdelhamid Mehri,LISIA Laboratory Faculty of NTIC,Constantine,Algeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Constantine 2 - Abdelhamid Mehri,LISIA Laboratory Faculty of NTIC,Constantine,Algeria","institution_ids":["https://openalex.org/I4210160465"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048803954","display_name":"Ly\u00e8s Mellal","orcid":"https://orcid.org/0000-0002-6330-930X"},"institutions":[{"id":"https://openalex.org/I4210117273","display_name":"\u00c9cole Nationale Sup\u00e9rieure d'Art","ror":"https://ror.org/02kgft750","country_code":"FR","type":"education","lineage":["https://openalex.org/I4210117273"]},{"id":"https://openalex.org/I4210143826","display_name":"Institut National des Sciences Appliqu\u00e9es Centre Val de Loire","ror":"https://ror.org/03y0qc033","country_code":"FR","type":"education","lineage":["https://openalex.org/I4210143826"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Ly\u00e8s Mellal","raw_affiliation_strings":["INSA CVL,Prisme UR 4229 Laboratory,Bourges,France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"INSA CVL,Prisme UR 4229 Laboratory,Bourges,France","institution_ids":["https://openalex.org/I4210117273","https://openalex.org/I4210143826"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014809852","display_name":"Ilham Kitouni","orcid":"https://orcid.org/0000-0001-6985-0124"},"institutions":[{"id":"https://openalex.org/I4210160465","display_name":"Universit\u00e9 Constantine 2","ror":"https://ror.org/056mctw68","country_code":"DZ","type":"education","lineage":["https://openalex.org/I4210160465"]}],"countries":["DZ"],"is_corresponding":false,"raw_author_name":"Ilham Kitouni","raw_affiliation_strings":["University of Constantine 2 - Abdelhamid Mehri,LISIA Laboratory Faculty of NTIC,Constantine,Algeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Constantine 2 - Abdelhamid Mehri,LISIA Laboratory Faculty of NTIC,Constantine,Algeria","institution_ids":["https://openalex.org/I4210160465"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5025474694","display_name":"Antoine Ferreira","orcid":"https://orcid.org/0000-0001-6295-3876"},"institutions":[{"id":"https://openalex.org/I4210117273","display_name":"\u00c9cole Nationale Sup\u00e9rieure d'Art","ror":"https://ror.org/02kgft750","country_code":"FR","type":"education","lineage":["https://openalex.org/I4210117273"]},{"id":"https://openalex.org/I4210143826","display_name":"Institut National des Sciences Appliqu\u00e9es Centre Val de Loire","ror":"https://ror.org/03y0qc033","country_code":"FR","type":"education","lineage":["https://openalex.org/I4210143826"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Antoine Ferreira","raw_affiliation_strings":["INSA CVL,Prisme UR 4229 Laboratory,Bourges,France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"INSA CVL,Prisme UR 4229 Laboratory,Bourges,France","institution_ids":["https://openalex.org/I4210117273","https://openalex.org/I4210143826"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.68753844,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"1","last_page":"5"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12422","display_name":"Radiomics and Machine Learning in Medical Imaging","score":0.0414000004529953,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12422","display_name":"Radiomics and Machine Learning in Medical Imaging","score":0.0414000004529953,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10063","display_name":"Nanoparticle-Based Drug Delivery","score":0.03889999911189079,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11176","display_name":"Radiation Therapy and Dosimetry","score":0.03530000150203705,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nanorobotics","display_name":"Nanorobotics","score":0.8723000288009644},{"id":"https://openalex.org/keywords/cancer","display_name":"Cancer","score":0.47940000891685486},{"id":"https://openalex.org/keywords/cancer-therapy","display_name":"Cancer therapy","score":0.4717000126838684},{"id":"https://openalex.org/keywords/drug","display_name":"Drug","score":0.367900013923645},{"id":"https://openalex.org/keywords/cancer-treatment","display_name":"Cancer treatment","score":0.3483999967575073},{"id":"https://openalex.org/keywords/calibration","display_name":"Calibration","score":0.3440999984741211}],"concepts":[{"id":"https://openalex.org/C187911381","wikidata":"https://www.wikidata.org/wiki/Q587024","display_name":"Nanorobotics","level":2,"score":0.8723000288009644},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.588100016117096},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.4966999888420105},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.47940000891685486},{"id":"https://openalex.org/C2983331546","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer therapy","level":3,"score":0.4717000126838684},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.43720000982284546},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.427700012922287},{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.367900013923645},{"id":"https://openalex.org/C3019816032","wikidata":"https://www.wikidata.org/wiki/Q2575340","display_name":"Cancer treatment","level":3,"score":0.3483999967575073},{"id":"https://openalex.org/C165838908","wikidata":"https://www.wikidata.org/wiki/Q736777","display_name":"Calibration","level":2,"score":0.3440999984741211},{"id":"https://openalex.org/C32220436","wikidata":"https://www.wikidata.org/wiki/Q2072214","display_name":"Personalized medicine","level":2,"score":0.3172000050544739},{"id":"https://openalex.org/C3020616263","wikidata":"https://www.wikidata.org/wiki/Q1216998","display_name":"Tumor cells","level":2,"score":0.3050999939441681},{"id":"https://openalex.org/C2992972558","wikidata":"https://www.wikidata.org/wiki/Q2509220","display_name":"Blood cancer","level":3,"score":0.302700012922287},{"id":"https://openalex.org/C3020340455","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Cancer drugs","level":3,"score":0.28929999470710754},{"id":"https://openalex.org/C2994119904","wikidata":"https://www.wikidata.org/wiki/Q1251001","display_name":"Drug response","level":3,"score":0.2874999940395355},{"id":"https://openalex.org/C163763905","wikidata":"https://www.wikidata.org/wiki/Q17075943","display_name":"Precision medicine","level":2,"score":0.26750001311302185}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/rif68108.2025.11406871","is_oa":false,"landing_page_url":"https://doi.org/10.1109/rif68108.2025.11406871","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2025 International Conference on Research in Computing at Feminine (RIF)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":16,"referenced_works":["https://openalex.org/W1964231254","https://openalex.org/W1973702777","https://openalex.org/W1979575182","https://openalex.org/W1999233462","https://openalex.org/W2004710504","https://openalex.org/W2033476934","https://openalex.org/W2117369794","https://openalex.org/W2130321554","https://openalex.org/W2154771107","https://openalex.org/W2199764170","https://openalex.org/W2325576256","https://openalex.org/W2921628782","https://openalex.org/W3194496349","https://openalex.org/W4242385451","https://openalex.org/W4393935425","https://openalex.org/W4409764905"],"related_works":[],"abstract_inverted_index":{"Cancer":[0],"is":[1,24,84],"a":[2,51,126,158,193],"leading":[3,191],"cause":[4],"of":[5,26,39,78,91,96,135,161],"mortality":[6],"worldwide.":[7],"Various":[8],"therapies":[9,30],"have":[10,48],"been":[11],"studied":[12],"to":[13,65,86,103,118,130,192],"maximize":[14],"treatment":[15],"effectiveness":[16],"while":[17,70,137],"minimizing":[18],"side":[19],"effects.":[20],"Antiangiogenic":[21],"therapy":[22],"(AAT)":[23],"one":[25],"the":[27,37,76,88,132,147,174],"molecularly":[28],"targeted":[29],"that":[31,143,173],"slows":[32],"tumor":[33,97,162],"growth":[34,163],"by":[35],"inhibiting":[36],"formation":[38],"new":[40],"blood":[41],"vessels.":[42],"Recently,":[43],"micro-":[44],"and":[45,57,98,115,140,195],"nanorobots":[46],"(MNBs)":[47],"emerged":[49],"as":[50],"promising":[52],"technology":[53],"for":[54,81,153,198],"drug":[55],"delivery,":[56],"combining":[58],"AAT":[59,136],"with":[60],"MNBs":[61,79],"allows":[62],"therapeutic":[63],"agents":[64],"reach":[66],"tumors":[67],"more":[68],"precisely":[69],"reducing":[71],"systemic":[72],"toxicity.":[73],"To":[74],"determine":[75,131],"number":[77],"required":[80],"therapy,":[82],"it":[83],"necessary":[85],"know":[87],"total":[89,182],"dose":[90,134],"AAT.":[92],"Traditionally,":[93],"mathematical":[94,148,159],"models":[95],"vascular":[99],"dynamics":[100],"are":[101,116],"used":[102,152],"estimate":[104],"this":[105,122],"optimal":[106,133],"dose,":[107],"but":[108,184],"they":[109],"may":[110,144],"require":[111],"complex":[112],"parameter":[113],"calibration":[114],"sensitive":[117],"biological":[119],"variability.":[120],"In":[121],"paper,":[123],"we":[124],"propose":[125],"machine":[127],"learning\u2013based":[128],"framework":[129,176],"also":[138,185],"detecting":[139],"correcting":[141],"anomalies":[142],"result":[145],"from":[146],"model.":[149],"The":[150],"dataset":[151],"training":[154],"was":[155],"generated":[156],"using":[157],"model":[160],"under":[164],"AAT,":[165],"allowing":[166],"realistic":[167],"patient":[168],"simulations.":[169],"Experimental":[170],"results":[171],"demonstrate":[172],"proposed":[175],"not":[177],"only":[178],"determines":[179],"accurate,":[180],"patient-specific":[181],"doses":[183],"successfully":[186],"corrects":[187],"all":[188],"detected":[189],"anomalies,":[190],"robust":[194],"reliable":[196],"strategy":[197],"personalized":[199],"cancer":[200],"treatment.":[201]},"counts_by_year":[],"updated_date":"2026-06-11T09:08:48.828518","created_date":"2026-02-27T00:00:00"}