{"id":"https://openalex.org/W4415378038","doi":"https://doi.org/10.1109/prime66228.2025.11203461","title":"Impact of the Sensor Electrical Noise on Ionoacoustic Dose Reconstruction using 200 MeV Clinical Proton Beam","display_name":"Impact of the Sensor Electrical Noise on Ionoacoustic Dose Reconstruction using 200 MeV Clinical Proton Beam","publication_year":2025,"publication_date":"2025-09-21","ids":{"openalex":"https://openalex.org/W4415378038","doi":"https://doi.org/10.1109/prime66228.2025.11203461"},"language":"en","primary_location":{"id":"doi:10.1109/prime66228.2025.11203461","is_oa":false,"landing_page_url":"https://doi.org/10.1109/prime66228.2025.11203461","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2025 20th International Conference on PhD Research in Microelectronics and Electronics (PRIME)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5082454198","display_name":"Alessandro Ferrara","orcid":"https://orcid.org/0000-0002-5821-5245"},"institutions":[{"id":"https://openalex.org/I138689650","display_name":"University of Padua","ror":"https://ror.org/00240q980","country_code":"IT","type":"education","lineage":["https://openalex.org/I138689650"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Alessandro Michele Ferrara","raw_affiliation_strings":["University of Padua,Department of Physics and Astronomy,Padua,Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Padua,Department of Physics and Astronomy,Padua,Italy","institution_ids":["https://openalex.org/I138689650"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103938333","display_name":"Saadat Ali","orcid":null},"institutions":[{"id":"https://openalex.org/I2800920820","display_name":"Istituto Universitario di Studi Superiori di Pavia","ror":"https://ror.org/0290wsh42","country_code":"IT","type":"education","lineage":["https://openalex.org/I2800920820"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Saadat Ali","raw_affiliation_strings":["Istituto Universitario di Studi Superiori (IUSS),Pavia,Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Istituto Universitario di Studi Superiori (IUSS),Pavia,Italy","institution_ids":["https://openalex.org/I2800920820"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038780136","display_name":"A. Bas\u00e7hirotto","orcid":"https://orcid.org/0000-0002-8844-5754"},"institutions":[{"id":"https://openalex.org/I4210140564","display_name":"Istituto Nazionale di Fisica Nucleare, Sezione di Milano Bicocca","ror":"https://ror.org/03xejxm22","country_code":"IT","type":"facility","lineage":["https://openalex.org/I160013858","https://openalex.org/I4210140564"]},{"id":"https://openalex.org/I66752286","display_name":"University of Milano-Bicocca","ror":"https://ror.org/01ynf4891","country_code":"IT","type":"education","lineage":["https://openalex.org/I66752286"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Andrea Baschirotto","raw_affiliation_strings":["University and Italian Institute for Nuclear Physics (INFN) Section of Milano - Bicocca,Milano,Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University and Italian Institute for Nuclear Physics (INFN) Section of Milano - Bicocca,Milano,Italy","institution_ids":["https://openalex.org/I4210140564","https://openalex.org/I66752286"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048447569","display_name":"Maurizio Marrale","orcid":"https://orcid.org/0000-0002-0091-3243"},"institutions":[{"id":"https://openalex.org/I900890020","display_name":"University of Palermo","ror":"https://ror.org/044k9ta02","country_code":"IT","type":"education","lineage":["https://openalex.org/I900890020"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Maurizio Marrale","raw_affiliation_strings":["University of Palermo,Department of Physics and Chemistry,Palermo,Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Palermo,Department of Physics and Chemistry,Palermo,Italy","institution_ids":["https://openalex.org/I900890020"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038131163","display_name":"Mara Severgnini","orcid":"https://orcid.org/0000-0002-2309-0737"},"institutions":[{"id":"https://openalex.org/I4210164020","display_name":"Azienda Sanitaria Universitaria Integrata di Trieste","ror":"https://ror.org/05g7qp006","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210164020"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Mara Severgnini","raw_affiliation_strings":["Azienda Sanitaria Universitaria Giuliano-Isontina (ASUGI),Department of Medical Physics,Trieste,Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Azienda Sanitaria Universitaria Giuliano-Isontina (ASUGI),Department of Medical Physics,Trieste,Italy","institution_ids":["https://openalex.org/I4210164020"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073082581","display_name":"Elia A. Vallicelli","orcid":"https://orcid.org/0000-0003-0905-151X"},"institutions":[{"id":"https://openalex.org/I4210140564","display_name":"Istituto Nazionale di Fisica Nucleare, Sezione di Milano Bicocca","ror":"https://ror.org/03xejxm22","country_code":"IT","type":"facility","lineage":["https://openalex.org/I160013858","https://openalex.org/I4210140564"]},{"id":"https://openalex.org/I66752286","display_name":"University of Milano-Bicocca","ror":"https://ror.org/01ynf4891","country_code":"IT","type":"education","lineage":["https://openalex.org/I66752286"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Elia Arturo Vallicelli","raw_affiliation_strings":["University and Italian Institute for Nuclear Physics (INFN) Section of Milano - Bicocca,Milano,Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University and Italian Institute for Nuclear Physics (INFN) Section of Milano - Bicocca,Milano,Italy","institution_ids":["https://openalex.org/I4210140564","https://openalex.org/I66752286"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5029585591","display_name":"Marcello De Matteis","orcid":"https://orcid.org/0000-0003-1061-1262"},"institutions":[{"id":"https://openalex.org/I4210140564","display_name":"Istituto Nazionale di Fisica Nucleare, Sezione di Milano Bicocca","ror":"https://ror.org/03xejxm22","country_code":"IT","type":"facility","lineage":["https://openalex.org/I160013858","https://openalex.org/I4210140564"]},{"id":"https://openalex.org/I66752286","display_name":"University of Milano-Bicocca","ror":"https://ror.org/01ynf4891","country_code":"IT","type":"education","lineage":["https://openalex.org/I66752286"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Marcello De Matteis","raw_affiliation_strings":["University and Italian Institute for Nuclear Physics (INFN) Section of Milano - Bicocca,Milano,Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University and Italian Institute for Nuclear Physics (INFN) Section of Milano - Bicocca,Milano,Italy","institution_ids":["https://openalex.org/I4210140564","https://openalex.org/I66752286"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.38998013,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"1","last_page":"4"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11176","display_name":"Radiation Therapy and Dosimetry","score":0.9952999949455261,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11176","display_name":"Radiation Therapy and Dosimetry","score":0.9952999949455261,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11949","display_name":"Nuclear Physics and Applications","score":0.9817000031471252,"subfield":{"id":"https://openalex.org/subfields/3108","display_name":"Radiation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12468","display_name":"Radiation Effects and Dosimetry","score":0.9567999839782715,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dosimetry","display_name":"Dosimetry","score":0.614300012588501},{"id":"https://openalex.org/keywords/proton","display_name":"Proton","score":0.5810999870300293},{"id":"https://openalex.org/keywords/proton-therapy","display_name":"Proton therapy","score":0.5785999894142151},{"id":"https://openalex.org/keywords/noise","display_name":"Noise (video)","score":0.5698999762535095},{"id":"https://openalex.org/keywords/range","display_name":"Range (aeronautics)","score":0.49549999833106995},{"id":"https://openalex.org/keywords/beam","display_name":"Beam (structure)","score":0.43689998984336853},{"id":"https://openalex.org/keywords/bragg-peak","display_name":"Bragg peak","score":0.40290001034736633},{"id":"https://openalex.org/keywords/dose-profile","display_name":"Dose profile","score":0.3693000078201294}],"concepts":[{"id":"https://openalex.org/C75088862","wikidata":"https://www.wikidata.org/wiki/Q2291081","display_name":"Dosimetry","level":2,"score":0.614300012588501},{"id":"https://openalex.org/C54516573","wikidata":"https://www.wikidata.org/wiki/Q2294","display_name":"Proton","level":2,"score":0.5810999870300293},{"id":"https://openalex.org/C2779244869","wikidata":"https://www.wikidata.org/wiki/Q507667","display_name":"Proton therapy","level":3,"score":0.5785999894142151},{"id":"https://openalex.org/C99498987","wikidata":"https://www.wikidata.org/wiki/Q2210247","display_name":"Noise (video)","level":3,"score":0.5698999762535095},{"id":"https://openalex.org/C204323151","wikidata":"https://www.wikidata.org/wiki/Q905424","display_name":"Range (aeronautics)","level":2,"score":0.49549999833106995},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.4864000082015991},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.44589999318122864},{"id":"https://openalex.org/C168834538","wikidata":"https://www.wikidata.org/wiki/Q3705329","display_name":"Beam (structure)","level":2,"score":0.43689998984336853},{"id":"https://openalex.org/C2780944729","wikidata":"https://www.wikidata.org/wiki/Q897227","display_name":"Bragg peak","level":3,"score":0.40290001034736633},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.3824999928474426},{"id":"https://openalex.org/C63007395","wikidata":"https://www.wikidata.org/wiki/Q2122891","display_name":"Dose profile","level":3,"score":0.3693000078201294},{"id":"https://openalex.org/C21200559","wikidata":"https://www.wikidata.org/wiki/Q7451068","display_name":"Sensitivity (control systems)","level":2,"score":0.3564000129699707},{"id":"https://openalex.org/C2780167933","wikidata":"https://www.wikidata.org/wiki/Q1550652","display_name":"Pulse (music)","level":3,"score":0.3452000021934509},{"id":"https://openalex.org/C55020928","wikidata":"https://www.wikidata.org/wiki/Q3813865","display_name":"Image quality","level":3,"score":0.32910001277923584},{"id":"https://openalex.org/C2779530757","wikidata":"https://www.wikidata.org/wiki/Q1207505","display_name":"Quality (philosophy)","level":2,"score":0.320499986410141},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.30970001220703125},{"id":"https://openalex.org/C13944312","wikidata":"https://www.wikidata.org/wiki/Q7512748","display_name":"Signal-to-noise ratio (imaging)","level":2,"score":0.3061000108718872},{"id":"https://openalex.org/C2984485829","wikidata":"https://www.wikidata.org/wiki/Q100766421","display_name":"Noise level","level":3,"score":0.30399999022483826},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.2922999858856201},{"id":"https://openalex.org/C19527891","wikidata":"https://www.wikidata.org/wiki/Q1120908","display_name":"Medical physics","level":1,"score":0.2896000146865845},{"id":"https://openalex.org/C106436119","wikidata":"https://www.wikidata.org/wiki/Q836575","display_name":"Quality assurance","level":3,"score":0.2703000009059906},{"id":"https://openalex.org/C105636585","wikidata":"https://www.wikidata.org/wiki/Q303665","display_name":"Dosimeter","level":3,"score":0.2662000060081482},{"id":"https://openalex.org/C141379421","wikidata":"https://www.wikidata.org/wiki/Q6094427","display_name":"Iterative reconstruction","level":2,"score":0.25760000944137573},{"id":"https://openalex.org/C35772409","wikidata":"https://www.wikidata.org/wiki/Q1323086","display_name":"Image noise","level":3,"score":0.2565999925136566}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1109/prime66228.2025.11203461","is_oa":false,"landing_page_url":"https://doi.org/10.1109/prime66228.2025.11203461","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2025 20th International Conference on PhD Research in Microelectronics and Electronics (PRIME)","raw_type":"proceedings-article"},{"id":"pmh:oai:boa.unimib.it:10281/594444","is_oa":false,"landing_page_url":"https://hdl.handle.net/10281/594444","pdf_url":null,"source":{"id":"https://openalex.org/S4306401259","display_name":"BOA (University of Milano-Bicocca)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I66752286","host_organization_name":"University of Milano-Bicocca","host_organization_lineage":["https://openalex.org/I66752286"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/conferenceObject"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320337512","display_name":"Nuclear Physics","ror":"https://ror.org/02atag894"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":9,"referenced_works":["https://openalex.org/W1985220060","https://openalex.org/W2139900007","https://openalex.org/W2887085435","https://openalex.org/W2901762611","https://openalex.org/W3093526971","https://openalex.org/W3152739785","https://openalex.org/W3179432870","https://openalex.org/W3180157116","https://openalex.org/W4403918796"],"related_works":[],"abstract_inverted_index":{"Ionoacoustic":[0],"dosimetry":[1,145],"has":[2],"emerged":[3],"as":[4],"a":[5,56,81],"promising":[6],"technique":[7],"for":[8,131,146,155],"real-time":[9],"dose":[10,33,52,77,94,124],"verification":[11],"in":[12],"proton":[13,59,149],"therapy,":[14],"where":[15],"conventional":[16],"methods":[17],"like":[18],"Electronic":[19],"Portal":[20],"Imaging":[21],"Devices":[22],"(EPIDs)":[23],"are":[24,126],"ineffective":[25],"due":[26],"to":[27],"the":[28,35,41,48,63,75,92,129,141],"absence":[29],"of":[30,43,51,83,91,143],"an":[31],"exit":[32],"beyond":[34],"Bragg":[36],"peak.":[37],"This":[38],"study":[39],"evaluates":[40],"impact":[42],"realistic":[44],"sensor":[45],"noise":[46,121],"on":[47],"ionoacoustic":[49,144],"reconstruction":[50],"distributions":[53,95],"generated":[54],"by":[55,73],"200":[57],"MeV":[58],"beam,":[60],"simulated":[61],"using":[62,98],"k":[64],"-Wave":[65],"toolbox.":[66],"Different":[67],"signal-to-noise":[68],"ratios":[69],"(SNRs)":[70],"were":[71],"modeled":[72],"varying":[74],"delivered":[76],"per":[78],"pulse":[79],"across":[80],"range":[82],"clinically":[84],"relevant":[85],"values":[86],"($1-100":[87],"\\mathrm{mGy}$).":[88],"The":[89],"quality":[90],"reconstructed":[93],"was":[96],"assessed":[97],"gamma":[99],"index":[100],"analysis":[101],"at":[102],"$1":[103],"\\%":[104,110],"/":[105,111],"1$":[106],"mm":[107],"and":[108,152,159],"$3":[109],"3":[112],"\\mathrm{~mm}$":[113],"criteria.":[114],"Results":[115],"demonstrate":[116],"that,":[117],"even":[118],"under":[119],"significant":[120],"conditions,":[122],"accurate":[123],"reconstructions":[125],"achievable":[127],"without":[128],"need":[130],"temporal":[132],"averaging,":[133],"provided":[134],"sufficient":[135],"per-pulse":[136],"dose.":[137],"These":[138],"findings":[139],"support":[140],"feasibility":[142],"online,":[147],"high-precision":[148],"therapy":[150],"monitoring":[151],"suggest":[153],"pathways":[154],"future":[156],"experimental":[157],"validation":[158],"clinical":[160],"translation.":[161]},"counts_by_year":[],"updated_date":"2026-06-11T09:08:48.828518","created_date":"2025-10-21T00:00:00"}