{"id":"https://openalex.org/W4377089459","doi":"https://doi.org/10.1109/ner52421.2023.10123735","title":"Intraretinal stimulation with high density carbon fiber microelectrodes","display_name":"Intraretinal stimulation with high density carbon fiber microelectrodes","publication_year":2023,"publication_date":"2023-04-24","ids":{"openalex":"https://openalex.org/W4377089459","doi":"https://doi.org/10.1109/ner52421.2023.10123735"},"language":"en","primary_location":{"id":"doi:10.1109/ner52421.2023.10123735","is_oa":false,"landing_page_url":"https://doi.org/10.1109/ner52421.2023.10123735","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2023 11th International IEEE/EMBS Conference on Neural Engineering (NER)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5020374280","display_name":"Dorsa Haji Ghaffari","orcid":"https://orcid.org/0000-0002-9600-5628"},"institutions":[{"id":"https://openalex.org/I27837315","display_name":"University of Michigan\u2013Ann Arbor","ror":"https://ror.org/00jmfr291","country_code":"US","type":"education","lineage":["https://openalex.org/I27837315"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Dorsa Haji Ghaffari","raw_affiliation_strings":["University of Michigan,Biomedical Engineering,Ann Arbor,MI,USA","Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA"],"affiliations":[{"raw_affiliation_string":"University of Michigan,Biomedical Engineering,Ann Arbor,MI,USA","institution_ids":["https://openalex.org/I27837315"]},{"raw_affiliation_string":"Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA","institution_ids":["https://openalex.org/I27837315"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026372286","display_name":"Elena della Valle","orcid":"https://orcid.org/0000-0001-8874-7982"},"institutions":[{"id":"https://openalex.org/I27837315","display_name":"University of Michigan\u2013Ann Arbor","ror":"https://ror.org/00jmfr291","country_code":"US","type":"education","lineage":["https://openalex.org/I27837315"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Elena Della Valle","raw_affiliation_strings":["University of Michigan,Biomedical Engineering,Ann Arbor,MI,USA","Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA"],"affiliations":[{"raw_affiliation_string":"University of Michigan,Biomedical Engineering,Ann Arbor,MI,USA","institution_ids":["https://openalex.org/I27837315"]},{"raw_affiliation_string":"Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA","institution_ids":["https://openalex.org/I27837315"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008298746","display_name":"Paras R. Patel","orcid":"https://orcid.org/0000-0001-6146-718X"},"institutions":[{"id":"https://openalex.org/I27837315","display_name":"University of Michigan\u2013Ann Arbor","ror":"https://ror.org/00jmfr291","country_code":"US","type":"education","lineage":["https://openalex.org/I27837315"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Paras R. Patel","raw_affiliation_strings":["University of Michigan,Biomedical Engineering,Ann Arbor,MI,USA","Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA"],"affiliations":[{"raw_affiliation_string":"University of Michigan,Biomedical Engineering,Ann Arbor,MI,USA","institution_ids":["https://openalex.org/I27837315"]},{"raw_affiliation_string":"Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA","institution_ids":["https://openalex.org/I27837315"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024233571","display_name":"Julianna M. Richie","orcid":"https://orcid.org/0000-0002-8920-6560"},"institutions":[{"id":"https://openalex.org/I27837315","display_name":"University of Michigan\u2013Ann Arbor","ror":"https://ror.org/00jmfr291","country_code":"US","type":"education","lineage":["https://openalex.org/I27837315"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Julianna Richie","raw_affiliation_strings":["University of Michigan,Biomedical Engineering,Ann Arbor,MI,USA","Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA"],"affiliations":[{"raw_affiliation_string":"University of Michigan,Biomedical Engineering,Ann Arbor,MI,USA","institution_ids":["https://openalex.org/I27837315"]},{"raw_affiliation_string":"Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA","institution_ids":["https://openalex.org/I27837315"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052017169","display_name":"Joseph G. Letner","orcid":"https://orcid.org/0000-0001-6584-6523"},"institutions":[{"id":"https://openalex.org/I27837315","display_name":"University of Michigan\u2013Ann Arbor","ror":"https://ror.org/00jmfr291","country_code":"US","type":"education","lineage":["https://openalex.org/I27837315"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joseph G. Letner","raw_affiliation_strings":["University of Michigan,Biomedical Engineering,Ann Arbor,MI,USA","Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA"],"affiliations":[{"raw_affiliation_string":"University of Michigan,Biomedical Engineering,Ann Arbor,MI,USA","institution_ids":["https://openalex.org/I27837315"]},{"raw_affiliation_string":"Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA","institution_ids":["https://openalex.org/I27837315"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037880597","display_name":"Cynthia A. Chestek","orcid":"https://orcid.org/0000-0002-9671-7051"},"institutions":[{"id":"https://openalex.org/I27837315","display_name":"University of Michigan\u2013Ann Arbor","ror":"https://ror.org/00jmfr291","country_code":"US","type":"education","lineage":["https://openalex.org/I27837315"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Cynthia A. Chestek","raw_affiliation_strings":["University of Michigan,Biomedical Engineering,Ann Arbor,MI,USA","Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA"],"affiliations":[{"raw_affiliation_string":"University of Michigan,Biomedical Engineering,Ann Arbor,MI,USA","institution_ids":["https://openalex.org/I27837315"]},{"raw_affiliation_string":"Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA","institution_ids":["https://openalex.org/I27837315"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5089711083","display_name":"James D. Weiland","orcid":"https://orcid.org/0000-0003-3453-9074"},"institutions":[{"id":"https://openalex.org/I27837315","display_name":"University of Michigan\u2013Ann Arbor","ror":"https://ror.org/00jmfr291","country_code":"US","type":"education","lineage":["https://openalex.org/I27837315"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James D. Weiland","raw_affiliation_strings":["University of Michigan,Biomedical Engineering,Ann Arbor,MI,USA","Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA"],"affiliations":[{"raw_affiliation_string":"University of Michigan,Biomedical Engineering,Ann Arbor,MI,USA","institution_ids":["https://openalex.org/I27837315"]},{"raw_affiliation_string":"Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA","institution_ids":["https://openalex.org/I27837315"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5020374280"],"corresponding_institution_ids":["https://openalex.org/I27837315"],"apc_list":null,"apc_paid":null,"fwci":0.461,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.58179911,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":96},"biblio":{"volume":null,"issue":null,"first_page":"1","last_page":"4"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11601","display_name":"Neuroscience and Neural Engineering","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11601","display_name":"Neuroscience and Neural Engineering","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10502","display_name":"Advanced Memory and Neural Computing","score":0.9988999962806702,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12236","display_name":"Photoreceptor and optogenetics research","score":0.9977999925613403,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/microelectrode","display_name":"Microelectrode","score":0.7494397759437561},{"id":"https://openalex.org/keywords/electrode","display_name":"Electrode","score":0.6638113260269165},{"id":"https://openalex.org/keywords/stimulation","display_name":"Stimulation","score":0.6527900099754333},{"id":"https://openalex.org/keywords/visual-prosthesis","display_name":"Visual prosthesis","score":0.6295312643051147},{"id":"https://openalex.org/keywords/retinal-implant","display_name":"Retinal implant","score":0.6273612380027771},{"id":"https://openalex.org/keywords/retinal","display_name":"Retinal","score":0.6265980005264282},{"id":"https://openalex.org/keywords/biomedical-engineering","display_name":"Biomedical engineering","score":0.5983557105064392},{"id":"https://openalex.org/keywords/retina","display_name":"Retina","score":0.5935853719711304},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.5690621137619019},{"id":"https://openalex.org/keywords/multielectrode-array","display_name":"Multielectrode array","score":0.4992353916168213},{"id":"https://openalex.org/keywords/electrode-array","display_name":"Electrode array","score":0.45408394932746887},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.3783162236213684},{"id":"https://openalex.org/keywords/ophthalmology","display_name":"Ophthalmology","score":0.2630009651184082},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.2502276301383972},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.21110790967941284},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.20785775780677795}],"concepts":[{"id":"https://openalex.org/C111670793","wikidata":"https://www.wikidata.org/wiki/Q16979465","display_name":"Microelectrode","level":3,"score":0.7494397759437561},{"id":"https://openalex.org/C17525397","wikidata":"https://www.wikidata.org/wiki/Q176140","display_name":"Electrode","level":2,"score":0.6638113260269165},{"id":"https://openalex.org/C24998067","wikidata":"https://www.wikidata.org/wiki/Q4114622","display_name":"Stimulation","level":2,"score":0.6527900099754333},{"id":"https://openalex.org/C2778560042","wikidata":"https://www.wikidata.org/wiki/Q540043","display_name":"Visual prosthesis","level":3,"score":0.6295312643051147},{"id":"https://openalex.org/C158383150","wikidata":"https://www.wikidata.org/wiki/Q3149439","display_name":"Retinal implant","level":3,"score":0.6273612380027771},{"id":"https://openalex.org/C2780827179","wikidata":"https://www.wikidata.org/wiki/Q422001","display_name":"Retinal","level":2,"score":0.6265980005264282},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.5983557105064392},{"id":"https://openalex.org/C2777093970","wikidata":"https://www.wikidata.org/wiki/Q169342","display_name":"Retina","level":2,"score":0.5935853719711304},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.5690621137619019},{"id":"https://openalex.org/C95967509","wikidata":"https://www.wikidata.org/wiki/Q1952355","display_name":"Multielectrode array","level":4,"score":0.4992353916168213},{"id":"https://openalex.org/C97562148","wikidata":"https://www.wikidata.org/wiki/Q5357989","display_name":"Electrode array","level":3,"score":0.45408394932746887},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.3783162236213684},{"id":"https://openalex.org/C118487528","wikidata":"https://www.wikidata.org/wiki/Q161437","display_name":"Ophthalmology","level":1,"score":0.2630009651184082},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2502276301383972},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.21110790967941284},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.20785775780677795},{"id":"https://openalex.org/C147789679","wikidata":"https://www.wikidata.org/wiki/Q11372","display_name":"Physical chemistry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/ner52421.2023.10123735","is_oa":false,"landing_page_url":"https://doi.org/10.1109/ner52421.2023.10123735","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2023 11th International IEEE/EMBS Conference on Neural Engineering (NER)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":30,"referenced_works":["https://openalex.org/W999143521","https://openalex.org/W1967720534","https://openalex.org/W1976408315","https://openalex.org/W1986651040","https://openalex.org/W2006868341","https://openalex.org/W2019083981","https://openalex.org/W2036085548","https://openalex.org/W2043873236","https://openalex.org/W2085039801","https://openalex.org/W2101656718","https://openalex.org/W2150645972","https://openalex.org/W2209723663","https://openalex.org/W2793133264","https://openalex.org/W2905487564","https://openalex.org/W2953775847","https://openalex.org/W3019246116","https://openalex.org/W3037823141","https://openalex.org/W3088051893","https://openalex.org/W3100415009","https://openalex.org/W3193765371","https://openalex.org/W3216789262","https://openalex.org/W4200184177","https://openalex.org/W4200300408","https://openalex.org/W4226061778","https://openalex.org/W4240629939","https://openalex.org/W4294128067","https://openalex.org/W4294543562","https://openalex.org/W6626267644","https://openalex.org/W6655269983","https://openalex.org/W6785253857"],"related_works":["https://openalex.org/W2028205923","https://openalex.org/W1637901622","https://openalex.org/W346203360","https://openalex.org/W2036589571","https://openalex.org/W2580354389","https://openalex.org/W4323040496","https://openalex.org/W2242980981","https://openalex.org/W2354662944","https://openalex.org/W4233525763","https://openalex.org/W2965952509"],"abstract_inverted_index":{"Retinal":[0],"prostheses":[1,23,204],"can":[2,43,179,194],"improve":[3],"vision":[4],"for":[5,57,90,202],"patients":[6],"blinded":[7],"by":[8,35],"photoreceptor":[9],"degenerative":[10],"diseases.":[11],"Despite":[12],"the":[13,25,162,186],"benefits":[14],"of":[15,21,28,77,109,142,151,164,173],"artificial":[16],"vision,":[17],"low":[18],"spatial":[19,107,127],"resolution":[20,65,201],"these":[22],"limits":[24,52],"positive":[26],"impact":[27],"clinically":[29],"available":[30],"devices.":[31],"Visual":[32],"percepts":[33],"generated":[34],"single":[36],"electrodes":[37,71,154],"in":[38,47,74,93,114,205],"epiretinal":[39],"and":[40,45,54,101,120,129,158,166,176,182,199],"subretinal":[41],"implants":[42],"overlap":[44],"result":[46],"an":[48,94,140],"unclear":[49],"image,":[50],"which":[51,137],"shape":[53],"letter":[55],"perception":[56],"retinal":[58,91,110,203],"prosthesis":[59],"users.":[60],"However,":[61],"research":[62],"suggests":[63],"higher":[64,134],"may":[66,138],"be":[67,139],"possible":[68],"with":[69,133,191],"smaller":[70,125],"implanted":[72],"intraretinally,":[73],"close":[75],"proximity":[76],"target":[78],"neurons.":[79],"In":[80],"this":[81],"study":[82],"we":[83],"used":[84],"penetrating":[85],"subcellular-scale":[86],"carbon":[87,152,192],"fiber":[88,153],"microelectrodes":[89],"stimulation":[92,118,132,190,197],"<tex":[95],"xmlns:mml=\"http://www.w3.org/1998/Math/MathML\"":[96],"xmlns:xlink=\"http://www.w3.org/1999/xlink\">$ex$</tex>":[97],"vivo":[98],"mouse":[99],"retina,":[100],"performed":[102],"calcium":[103],"imaging":[104],"to":[105,116],"record":[106],"activation":[108,145],"ganglion":[111],"cells":[112],"(RGC)":[113],"response":[115],"different":[117],"amplitudes":[119,175],"RGC-electrode":[121,135],"distances.":[122],"We":[123],"observed":[124],"RGC":[126,144],"activities":[128],"less":[130],"off-target":[131],"distances,":[136],"indication":[141],"indirect":[143],"through":[146],"bipolar":[147],"cells.":[148],"Impedance":[149],"measurements":[150],"demonstrated":[155],"their":[156],"mechanical":[157],"electrical":[159],"stability":[160],"throughout":[161],"process":[163],"insertion":[165],"stimulation.":[167],"Our":[168],"results":[169],"indicate":[170],"that":[171],"modification":[172],"pulse":[174],"electrode":[177],"depths":[178],"create":[180],"small":[181],"focal":[183],"responses":[184],"around":[185],"active":[187],"electrode.":[188],"Intraretinal":[189],"fibers":[193],"potentially":[195],"increase":[196],"precision":[198],"image":[200],"clinical":[206],"applications.":[207]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":2}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}