{"id":"https://openalex.org/W3167278262","doi":"https://doi.org/10.1109/ner49283.2021.9441106","title":"In Vivo Measurements of Cranial Electrical Stimulation Using Stereotactic-EEG: A Pilot Study","display_name":"In Vivo Measurements of Cranial Electrical Stimulation Using Stereotactic-EEG: A Pilot Study","publication_year":2021,"publication_date":"2021-05-04","ids":{"openalex":"https://openalex.org/W3167278262","doi":"https://doi.org/10.1109/ner49283.2021.9441106","mag":"3167278262"},"language":"en","primary_location":{"id":"doi:10.1109/ner49283.2021.9441106","is_oa":false,"landing_page_url":"https://doi.org/10.1109/ner49283.2021.9441106","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2021 10th International IEEE/EMBS Conference on Neural Engineering (NER)","raw_type":"proceedings-article"},"type":"conference-paper","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5084754315","display_name":"Minmin Wang","orcid":"https://orcid.org/0000-0003-0016-2985"},"institutions":[{"id":"https://openalex.org/I4210123185","display_name":"Zhejiang Lab","ror":"https://ror.org/02m2h7991","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210123185"]},{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Minmin Wang","raw_affiliation_strings":["Qiushi Academy for Advanced Studies, MOE Frontier Science Center for Brain Research and Brain-Machine Integration, Zhejiang University, Hangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Qiushi Academy for Advanced Studies, MOE Frontier Science Center for Brain Research and Brain-Machine Integration, Zhejiang University, Hangzhou, China","institution_ids":["https://openalex.org/I4210123185","https://openalex.org/I76130692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038247363","display_name":"Shenghua Zhu","orcid":null},"institutions":[{"id":"https://openalex.org/I4210123185","display_name":"Zhejiang Lab","ror":"https://ror.org/02m2h7991","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210123185"]},{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shenghua Zhu","raw_affiliation_strings":["Qiushi Academy for Advanced Studies, MOE Frontier Science Center for Brain Research and Brain-Machine Integration, Zhejiang University, Hangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Qiushi Academy for Advanced Studies, MOE Frontier Science Center for Brain Research and Brain-Machine Integration, Zhejiang University, Hangzhou, China","institution_ids":["https://openalex.org/I4210123185","https://openalex.org/I76130692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031493782","display_name":"Haonan Guan","orcid":"https://orcid.org/0000-0001-8924-8624"},"institutions":[{"id":"https://openalex.org/I4210123185","display_name":"Zhejiang Lab","ror":"https://ror.org/02m2h7991","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210123185"]},{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Haonan Guan","raw_affiliation_strings":["Qiushi Academy for Advanced Studies, MOE Frontier Science Center for Brain Research and Brain-Machine Integration, Zhejiang University, Hangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Qiushi Academy for Advanced Studies, MOE Frontier Science Center for Brain Research and Brain-Machine Integration, Zhejiang University, Hangzhou, China","institution_ids":["https://openalex.org/I4210123185","https://openalex.org/I76130692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036325675","display_name":"Hongjie Jiang","orcid":"https://orcid.org/0000-0001-7690-4434"},"institutions":[{"id":"https://openalex.org/I4210158318","display_name":"Second Affiliated Hospital of Zhejiang University","ror":"https://ror.org/059cjpv64","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210158318"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hongjie Jiang","raw_affiliation_strings":["Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China","institution_ids":["https://openalex.org/I4210158318"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100444663","display_name":"Jianmin Zhang","orcid":"https://orcid.org/0000-0002-3184-1502"},"institutions":[{"id":"https://openalex.org/I4210158318","display_name":"Second Affiliated Hospital of Zhejiang University","ror":"https://ror.org/059cjpv64","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210158318"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jianmin Zhang","raw_affiliation_strings":["Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China","institution_ids":["https://openalex.org/I4210158318"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5009996306","display_name":"Shaomin Zhang","orcid":"https://orcid.org/0000-0001-6311-5946"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Shaomin Zhang","raw_affiliation_strings":["MOE Frontier Science Center for Brain Research and Brain-Machine Integration, Zhejiang University, Qiushi Academy for Advanced Studies, Zhejiang Provincial Key Laboratory of Cardio-Cerebral Vascular Detection Technology and Medicinal Effectiveness Appraisal, Hangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"MOE Frontier Science Center for Brain Research and Brain-Machine Integration, Zhejiang University, Qiushi Academy for Advanced Studies, Zhejiang Provincial Key Laboratory of Cardio-Cerebral Vascular Detection Technology and Medicinal Effectiveness Appraisal, Hangzhou, China","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"10","issue":null,"first_page":"560","last_page":"563"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10429","display_name":"EEG and Brain-Computer Interfaces","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10429","display_name":"EEG and Brain-Computer Interfaces","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10241","display_name":"Functional Brain Connectivity Studies","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10378","display_name":"Advanced MRI Techniques and Applications","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/stereoelectroencephalography","display_name":"Stereoelectroencephalography","score":0.7455865144729614},{"id":"https://openalex.org/keywords/stimulation","display_name":"Stimulation","score":0.722183108329773},{"id":"https://openalex.org/keywords/electric-field","display_name":"Electric field","score":0.6371862292289734},{"id":"https://openalex.org/keywords/biomedical-engineering","display_name":"Biomedical engineering","score":0.6193898916244507},{"id":"https://openalex.org/keywords/electroencephalography","display_name":"Electroencephalography","score":0.5976253151893616},{"id":"https://openalex.org/keywords/in-vivo","display_name":"In vivo","score":0.5806260704994202},{"id":"https://openalex.org/keywords/epilepsy","display_name":"Epilepsy","score":0.567833423614502},{"id":"https://openalex.org/keywords/deep-brain-stimulation","display_name":"Deep brain stimulation","score":0.5487372279167175},{"id":"https://openalex.org/keywords/voltage","display_name":"Voltage","score":0.547107994556427},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.41869693994522095},{"id":"https://openalex.org/keywords/local-field-potential","display_name":"Local field potential","score":0.4122655391693115},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.37368786334991455},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.3215066194534302},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.3083728551864624},{"id":"https://openalex.org/keywords/epilepsy-surgery","display_name":"Epilepsy surgery","score":0.2854172885417938},{"id":"https://openalex.org/keywords/psychology","display_name":"Psychology","score":0.12862041592597961},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.09509161114692688},{"id":"https://openalex.org/keywords/pathology","display_name":"Pathology","score":0.08886769413948059}],"concepts":[{"id":"https://openalex.org/C98254291","wikidata":"https://www.wikidata.org/wiki/Q7611238","display_name":"Stereoelectroencephalography","level":4,"score":0.7455865144729614},{"id":"https://openalex.org/C24998067","wikidata":"https://www.wikidata.org/wiki/Q4114622","display_name":"Stimulation","level":2,"score":0.722183108329773},{"id":"https://openalex.org/C60799052","wikidata":"https://www.wikidata.org/wiki/Q46221","display_name":"Electric field","level":2,"score":0.6371862292289734},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.6193898916244507},{"id":"https://openalex.org/C522805319","wikidata":"https://www.wikidata.org/wiki/Q179965","display_name":"Electroencephalography","level":2,"score":0.5976253151893616},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.5806260704994202},{"id":"https://openalex.org/C2778186239","wikidata":"https://www.wikidata.org/wiki/Q41571","display_name":"Epilepsy","level":2,"score":0.567833423614502},{"id":"https://openalex.org/C2778542668","wikidata":"https://www.wikidata.org/wiki/Q618076","display_name":"Deep brain stimulation","level":4,"score":0.5487372279167175},{"id":"https://openalex.org/C165801399","wikidata":"https://www.wikidata.org/wiki/Q25428","display_name":"Voltage","level":2,"score":0.547107994556427},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.41869693994522095},{"id":"https://openalex.org/C117838684","wikidata":"https://www.wikidata.org/wiki/Q533483","display_name":"Local field potential","level":2,"score":0.4122655391693115},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.37368786334991455},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.3215066194534302},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3083728551864624},{"id":"https://openalex.org/C2780803581","wikidata":"https://www.wikidata.org/wiki/Q1347108","display_name":"Epilepsy surgery","level":3,"score":0.2854172885417938},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.12862041592597961},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.09509161114692688},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.08886769413948059},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.0},{"id":"https://openalex.org/C2779734285","wikidata":"https://www.wikidata.org/wiki/Q11085","display_name":"Parkinson's disease","level":3,"score":0.0},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/ner49283.2021.9441106","is_oa":false,"landing_page_url":"https://doi.org/10.1109/ner49283.2021.9441106","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2021 10th International IEEE/EMBS Conference on Neural Engineering (NER)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G3273801785","display_name":null,"funder_award_id":"2019FZJD005,K20200185","funder_id":"https://openalex.org/F4320335787","funder_display_name":"Fundamental Research Funds for the Central Universities"},{"id":"https://openalex.org/G6778601164","display_name":null,"funder_award_id":"2017YFC1308501,2017YFE0195500","funder_id":"https://openalex.org/F4320335777","funder_display_name":"National Key Research and Development Program of China"},{"id":"https://openalex.org/G90640612","display_name":null,"funder_award_id":"31627802,31371001","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320335777","display_name":"National Key Research and Development Program of China","ror":null},{"id":"https://openalex.org/F4320335787","display_name":"Fundamental Research Funds for the Central Universities","ror":null}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":21,"referenced_works":["https://openalex.org/W1561905643","https://openalex.org/W2012621586","https://openalex.org/W2014502281","https://openalex.org/W2131637059","https://openalex.org/W2139852882","https://openalex.org/W2140398789","https://openalex.org/W2155655165","https://openalex.org/W2169387292","https://openalex.org/W2410520768","https://openalex.org/W2412613259","https://openalex.org/W2516154248","https://openalex.org/W2539155651","https://openalex.org/W2587386871","https://openalex.org/W2598015258","https://openalex.org/W2736217636","https://openalex.org/W2790131028","https://openalex.org/W2792815456","https://openalex.org/W2811241336","https://openalex.org/W2898891076","https://openalex.org/W4232313037","https://openalex.org/W6714625576"],"related_works":["https://openalex.org/W2025347688","https://openalex.org/W1533811891","https://openalex.org/W2043401111","https://openalex.org/W1975718671","https://openalex.org/W2056777881","https://openalex.org/W4379385222","https://openalex.org/W4250102971","https://openalex.org/W3081635124","https://openalex.org/W2463887593","https://openalex.org/W2056849177"],"abstract_inverted_index":{"Cranial":[0],"Electrical":[1],"Stimulation":[2],"(CES)":[3],"is":[4],"a":[5,104],"promising":[6],"non-invasive":[7],"brain":[8],"modulation":[9],"technique":[10],"in":[11,34,52,94,136,150,164],"clinical":[12],"application.":[13],"However,":[14],"whether":[15],"CES":[16,85,108,156],"could":[17,158],"provide":[18],"sufficient":[19],"intracerebral":[20],"currents":[21],"and":[22,132],"influence":[23],"neural":[24],"activity":[25],"remains":[26],"controversial":[27],"because":[28],"of":[29,32,66,99],"the":[30,80,90,107,142,155,160,165],"lack":[31],"direct":[33],"vivo":[35,137,151],"evidence":[36],"for":[37],"CES-induced":[38,49],"electric":[39,133,161],"field":[40,162],"distribution.":[41],"In":[42],"this":[43,149],"pilot":[44],"study,":[45],"we":[46,125],"directly":[47],"measured":[48,81,100,130],"voltage":[50],"distribution":[51],"two":[53],"epilepsy":[54],"participants":[55],"undergoing":[56],"presurgical":[57],"evaluation":[58],"with":[59,89,118,141],"stereotactic-electroencephalographic":[60],"(sEEG).":[61],"An":[62],"alternating":[63],"sinusoidal":[64],"current":[65],"0.005":[67],"to":[68,72,114],"0.5":[69,71,113],"mA,":[70],"200":[73,115],"Hz":[74],"was":[75],"applied.":[76],"We":[77],"found":[78],"that":[79,128,154],"voltages":[82,101,131],"induced":[83],"by":[84],"increased":[86,111],"their":[87],"magnitudes":[88,98],"stimulation":[91,109,157],"intensity":[92],"linearly":[93],"all":[95],"electrodes.":[96],"The":[97,145],"changed":[102],"only":[103],"little":[105],"when":[106],"frequency":[110],"from":[112,148],"Hz.":[116],"Combing":[117],"numerical":[119],"simulations":[120],"based":[121],"on":[122],"individual":[123],"MRI,":[124],"further":[126],"observed":[127],"both":[129],"fields":[134],"obtained":[135],"are":[138],"highly":[139],"correlated":[140],"predicted":[143],"ones.":[144],"preliminary":[146],"result":[147],"study":[152],"suggested":[153],"induce":[159],"changes":[163],"deep":[166],"brain.":[167]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1}],"updated_date":"2026-07-14T23:27:15.235271","created_date":"2025-10-10T00:00:00"}