{"id":"https://openalex.org/W2742687316","doi":"https://doi.org/10.1109/ner.2017.8008342","title":"Microtunnel-electrode device for elucidating axon features: Toward pharmacological manipulation of individual axons","display_name":"Microtunnel-electrode device for elucidating axon features: Toward pharmacological manipulation of individual axons","publication_year":2017,"publication_date":"2017-05-01","ids":{"openalex":"https://openalex.org/W2742687316","doi":"https://doi.org/10.1109/ner.2017.8008342","mag":"2742687316"},"language":"en","primary_location":{"id":"doi:10.1109/ner.2017.8008342","is_oa":false,"landing_page_url":"https://doi.org/10.1109/ner.2017.8008342","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2017 8th International IEEE/EMBS Conference on Neural Engineering (NER)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5090447356","display_name":"Kenta Shimba","orcid":"https://orcid.org/0000-0003-1156-260X"},"institutions":[{"id":"https://openalex.org/I114531698","display_name":"Tokyo Institute of Technology","ror":"https://ror.org/0112mx960","country_code":"JP","type":"education","lineage":["https://openalex.org/I114531698"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Kenta Shimba","raw_affiliation_strings":["Tokyo Institute of Technology, Meguro-ku, Tokyo, Japan"],"affiliations":[{"raw_affiliation_string":"Tokyo Institute of Technology, Meguro-ku, Tokyo, Japan","institution_ids":["https://openalex.org/I114531698"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023773587","display_name":"Koji Sakai","orcid":"https://orcid.org/0000-0002-5585-7074"},"institutions":[{"id":"https://openalex.org/I74801974","display_name":"The University of Tokyo","ror":"https://ror.org/057zh3y96","country_code":"JP","type":"education","lineage":["https://openalex.org/I74801974"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Koji Sakai","raw_affiliation_strings":["University of Tokyo, Bukyo-ku, Tokyo, Japan"],"affiliations":[{"raw_affiliation_string":"University of Tokyo, Bukyo-ku, Tokyo, Japan","institution_ids":["https://openalex.org/I74801974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108832608","display_name":"Kiyoshi Kotani","orcid":null},"institutions":[{"id":"https://openalex.org/I74801974","display_name":"The University of Tokyo","ror":"https://ror.org/057zh3y96","country_code":"JP","type":"education","lineage":["https://openalex.org/I74801974"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kiyoshi Kotani","raw_affiliation_strings":["PRESTO JST, University of Tokyo, Meguro-ku, Tokyo, Japan"],"affiliations":[{"raw_affiliation_string":"PRESTO JST, University of Tokyo, Meguro-ku, Tokyo, Japan","institution_ids":["https://openalex.org/I74801974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064090059","display_name":"T. Yagi","orcid":"https://orcid.org/0000-0001-7040-0067"},"institutions":[{"id":"https://openalex.org/I114531698","display_name":"Tokyo Institute of Technology","ror":"https://ror.org/0112mx960","country_code":"JP","type":"education","lineage":["https://openalex.org/I114531698"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Tohru Yagi","raw_affiliation_strings":["Tokyo Institute of Technology, Meguro-ku, Tokyo, Japan"],"affiliations":[{"raw_affiliation_string":"Tokyo Institute of Technology, Meguro-ku, Tokyo, Japan","institution_ids":["https://openalex.org/I114531698"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5032635092","display_name":"Yasuhiko Jimbo","orcid":"https://orcid.org/0009-0004-6005-5043"},"institutions":[{"id":"https://openalex.org/I74801974","display_name":"The University of Tokyo","ror":"https://ror.org/057zh3y96","country_code":"JP","type":"education","lineage":["https://openalex.org/I74801974"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yasuhiko Jimbo","raw_affiliation_strings":["University of Tokyo, Bukyo-ku, Tokyo, Japan"],"affiliations":[{"raw_affiliation_string":"University of Tokyo, Bukyo-ku, Tokyo, Japan","institution_ids":["https://openalex.org/I74801974"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5090447356"],"corresponding_institution_ids":["https://openalex.org/I114531698"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.09090909,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"267","last_page":"270"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11601","display_name":"Neuroscience and Neural Engineering","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11601","display_name":"Neuroscience and Neural Engineering","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12236","display_name":"Photoreceptor and optogenetics research","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11190","display_name":"3D Printing in Biomedical Research","score":0.9952999949455261,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/axon","display_name":"Axon","score":0.7533270120620728},{"id":"https://openalex.org/keywords/nerve-conduction-velocity","display_name":"Nerve conduction velocity","score":0.6690434813499451},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.6501888036727905},{"id":"https://openalex.org/keywords/thermal-conduction","display_name":"Thermal conduction","score":0.6361531019210815},{"id":"https://openalex.org/keywords/electrode","display_name":"Electrode","score":0.584592878818512},{"id":"https://openalex.org/keywords/substrate","display_name":"Substrate (aquarium)","score":0.4533421993255615},{"id":"https://openalex.org/keywords/interconnection","display_name":"Interconnection","score":0.45121458172798157},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.4155692458152771},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.37689363956451416},{"id":"https://openalex.org/keywords/biophysics","display_name":"Biophysics","score":0.3386029601097107},{"id":"https://openalex.org/keywords/biomedical-engineering","display_name":"Biomedical engineering","score":0.3218322992324829},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.32155758142471313},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.31905925273895264},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.12857520580291748},{"id":"https://openalex.org/keywords/telecommunications","display_name":"Telecommunications","score":0.07545536756515503}],"concepts":[{"id":"https://openalex.org/C2779530196","wikidata":"https://www.wikidata.org/wiki/Q178999","display_name":"Axon","level":2,"score":0.7533270120620728},{"id":"https://openalex.org/C179253579","wikidata":"https://www.wikidata.org/wiki/Q6276958","display_name":"Nerve conduction velocity","level":2,"score":0.6690434813499451},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.6501888036727905},{"id":"https://openalex.org/C172100665","wikidata":"https://www.wikidata.org/wiki/Q7465774","display_name":"Thermal conduction","level":2,"score":0.6361531019210815},{"id":"https://openalex.org/C17525397","wikidata":"https://www.wikidata.org/wiki/Q176140","display_name":"Electrode","level":2,"score":0.584592878818512},{"id":"https://openalex.org/C2777289219","wikidata":"https://www.wikidata.org/wiki/Q7632154","display_name":"Substrate (aquarium)","level":2,"score":0.4533421993255615},{"id":"https://openalex.org/C123745756","wikidata":"https://www.wikidata.org/wiki/Q1665949","display_name":"Interconnection","level":2,"score":0.45121458172798157},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.4155692458152771},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.37689363956451416},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.3386029601097107},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.3218322992324829},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.32155758142471313},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.31905925273895264},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.12857520580291748},{"id":"https://openalex.org/C76155785","wikidata":"https://www.wikidata.org/wiki/Q418","display_name":"Telecommunications","level":1,"score":0.07545536756515503},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.0},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.0},{"id":"https://openalex.org/C147789679","wikidata":"https://www.wikidata.org/wiki/Q11372","display_name":"Physical chemistry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/ner.2017.8008342","is_oa":false,"landing_page_url":"https://doi.org/10.1109/ner.2017.8008342","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2017 8th International IEEE/EMBS Conference on Neural Engineering (NER)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":15,"referenced_works":["https://openalex.org/W1136909202","https://openalex.org/W1976765976","https://openalex.org/W1993305789","https://openalex.org/W1993899334","https://openalex.org/W2022659970","https://openalex.org/W2028120927","https://openalex.org/W2035302951","https://openalex.org/W2036564583","https://openalex.org/W2064241002","https://openalex.org/W2068633735","https://openalex.org/W2071365886","https://openalex.org/W2094137543","https://openalex.org/W2131301953","https://openalex.org/W2157485677","https://openalex.org/W2401571481"],"related_works":["https://openalex.org/W2122884624","https://openalex.org/W2014709025","https://openalex.org/W2155019192","https://openalex.org/W3125341812","https://openalex.org/W1991674760","https://openalex.org/W1668171714","https://openalex.org/W2155297398","https://openalex.org/W2127637679","https://openalex.org/W4380607112","https://openalex.org/W2078379813"],"abstract_inverted_index":{"Neural":[0],"networks":[1],"in":[2,94,100],"the":[3,65],"central":[4],"nervous":[5],"system":[6],"are":[7],"composed":[8],"of":[9,19,22,35,38,113],"neurons":[10,115],"which":[11],"interconnect":[12],"through":[13,142],"their":[14,25,123,127,147],"axons.":[15,63],"Although":[16],"computational":[17],"capacity":[18],"axons":[20,40,76,112,144],"is":[21,46,109,137],"great":[23],"interest,":[24],"small":[26],"structure":[27],"makes":[28],"exact":[29],"evaluation":[30],"difficult.":[31],"Culture":[32],"device":[33,58,67,136],"capable":[34],"obtaining":[36],"features":[37],"individual":[39,143],"and":[41,61,70,83,97,120,145],"stimulating":[42,62],"with":[43,88],"pharmacological":[44],"reagent":[45],"needed.":[47],"In":[48],"this":[49],"study,":[50],"we":[51],"aimed":[52],"to":[53,139],"develop":[54],"a":[55,106],"novel":[56],"culture":[57,66,135],"for":[59],"evaluating":[60],"First,":[64],"was":[68],"fabricated":[69],"neuronal":[71],"cells":[72],"were":[73,77,86,103],"cultured.":[74],"Their":[75],"maintained":[78],"more":[79],"than":[80],"30":[81],"days":[82],"axonal":[84],"conductions":[85],"detected":[87],"substrate-embedded":[89],"electrodes.":[90],"Second,":[91],"developmental":[92],"changes":[93,99],"conduction":[95,101,118,124,141],"delay":[96],"activity-dependent":[98],"velocity":[102,119,125],"evaluated.":[104],"As":[105],"result,":[107],"it":[108],"suggested":[110],"that":[111,133],"younger":[114],"have":[116],"lower":[117],"easily":[121],"change":[122],"by":[126],"firing":[128],"frequency.":[129],"These":[130],"results":[131],"show":[132],"our":[134],"feasible":[138],"record":[140],"evaluate":[146],"feature.":[148]},"counts_by_year":[],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}