{"id":"https://openalex.org/W2743480564","doi":"https://doi.org/10.1109/ner.2017.8008333","title":"Microelectrode arrays studies of glutamate excitatory pathway in hippocampus CA3 by offside KCl and glutamate stimulating","display_name":"Microelectrode arrays studies of glutamate excitatory pathway in hippocampus CA3 by offside KCl and glutamate stimulating","publication_year":2017,"publication_date":"2017-05-01","ids":{"openalex":"https://openalex.org/W2743480564","doi":"https://doi.org/10.1109/ner.2017.8008333","mag":"2743480564"},"language":"en","primary_location":{"id":"doi:10.1109/ner.2017.8008333","is_oa":false,"landing_page_url":"https://doi.org/10.1109/ner.2017.8008333","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2017 8th International IEEE/EMBS Conference on Neural Engineering (NER)","raw_type":"proceedings-article"},"type":"conference-paper","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5053829990","display_name":"Guihua Xiao","orcid":"https://orcid.org/0000-0002-2705-6827"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210110458","display_name":"Institute of Electronics","ror":"https://ror.org/01z143507","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210110458"]},{"id":"https://openalex.org/I4210165038","display_name":"University of Chinese Academy of Sciences","ror":"https://ror.org/05qbk4x57","country_code":"CN","type":"education","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210165038"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Guihua Xiao","raw_affiliation_strings":["Chinese Academy of Sciences, Institute of Electronics, Beijing, China","University of Chinese Academy of Sciences, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chinese Academy of Sciences, Institute of Electronics, Beijing, China","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210110458"]},{"raw_affiliation_string":"University of Chinese Academy of Sciences, Beijing, China","institution_ids":["https://openalex.org/I4210165038"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101932954","display_name":"Yilin Song","orcid":"https://orcid.org/0000-0001-7756-5139"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210110458","display_name":"Institute of Electronics","ror":"https://ror.org/01z143507","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210110458"]},{"id":"https://openalex.org/I4210165038","display_name":"University of Chinese Academy of Sciences","ror":"https://ror.org/05qbk4x57","country_code":"CN","type":"education","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210165038"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yilin Song","raw_affiliation_strings":["Chinese Academy of Sciences, Institute of Electronics, Beijing, China","University of Chinese Academy of Sciences, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chinese Academy of Sciences, Institute of Electronics, Beijing, China","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210110458"]},{"raw_affiliation_string":"University of Chinese Academy of Sciences, Beijing, China","institution_ids":["https://openalex.org/I4210165038"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110947587","display_name":"Song Zhang","orcid":"https://orcid.org/0000-0001-9816-4094"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210110458","display_name":"Institute of Electronics","ror":"https://ror.org/01z143507","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210110458"]},{"id":"https://openalex.org/I4210165038","display_name":"University of Chinese Academy of Sciences","ror":"https://ror.org/05qbk4x57","country_code":"CN","type":"education","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210165038"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Song Zhang","raw_affiliation_strings":["Chinese Academy of Sciences, Institute of Electronics, Beijing, China","University of Chinese Academy of Sciences, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chinese Academy of Sciences, Institute of Electronics, Beijing, China","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210110458"]},{"raw_affiliation_string":"University of Chinese Academy of Sciences, Beijing, China","institution_ids":["https://openalex.org/I4210165038"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110638775","display_name":"Shengwei Xu","orcid":"https://orcid.org/0009-0007-4532-5385"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210110458","display_name":"Institute of Electronics","ror":"https://ror.org/01z143507","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210110458"]},{"id":"https://openalex.org/I4210165038","display_name":"University of Chinese Academy of Sciences","ror":"https://ror.org/05qbk4x57","country_code":"CN","type":"education","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210165038"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shengwei Xu","raw_affiliation_strings":["Chinese Academy of Sciences, Institute of Electronics, Beijing, China","University of Chinese Academy of Sciences, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chinese Academy of Sciences, Institute of Electronics, Beijing, China","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210110458"]},{"raw_affiliation_string":"University of Chinese Academy of Sciences, Beijing, China","institution_ids":["https://openalex.org/I4210165038"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102773683","display_name":"Lili Yang","orcid":"https://orcid.org/0000-0001-6152-9440"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210110458","display_name":"Institute of Electronics","ror":"https://ror.org/01z143507","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210110458"]},{"id":"https://openalex.org/I4210165038","display_name":"University of Chinese Academy of Sciences","ror":"https://ror.org/05qbk4x57","country_code":"CN","type":"education","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210165038"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lili Yang","raw_affiliation_strings":["Chinese Academy of Sciences, Institute of Electronics, Beijing, China","University of Chinese Academy of Sciences, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chinese Academy of Sciences, Institute of Electronics, Beijing, China","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210110458"]},{"raw_affiliation_string":"University of Chinese Academy of Sciences, Beijing, China","institution_ids":["https://openalex.org/I4210165038"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075332400","display_name":"Huiren Xu","orcid":null},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210110458","display_name":"Institute of Electronics","ror":"https://ror.org/01z143507","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210110458"]},{"id":"https://openalex.org/I4210165038","display_name":"University of Chinese Academy of Sciences","ror":"https://ror.org/05qbk4x57","country_code":"CN","type":"education","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210165038"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Huiren Xu","raw_affiliation_strings":["Chinese Academy of Sciences, Institute of Electronics, Beijing, China","University of Chinese Academy of Sciences, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chinese Academy of Sciences, Institute of Electronics, Beijing, China","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210110458"]},{"raw_affiliation_string":"University of Chinese Academy of Sciences, Beijing, China","institution_ids":["https://openalex.org/I4210165038"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111695012","display_name":"Xinxia Cai","orcid":"https://orcid.org/0000-0001-5997-7252"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210110458","display_name":"Institute of Electronics","ror":"https://ror.org/01z143507","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210110458"]},{"id":"https://openalex.org/I4210165038","display_name":"University of Chinese Academy of Sciences","ror":"https://ror.org/05qbk4x57","country_code":"CN","type":"education","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210165038"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xinxia Cai","raw_affiliation_strings":["Chinese Academy of Sciences, Institute of Electronics, Beijing, China","University of Chinese Academy of Sciences, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chinese Academy of Sciences, Institute of Electronics, Beijing, China","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210110458"]},{"raw_affiliation_string":"University of Chinese Academy of Sciences, Beijing, China","institution_ids":["https://openalex.org/I4210165038"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.495,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.75515152,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":94},"biblio":{"volume":null,"issue":null,"first_page":"231","last_page":"234"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11601","display_name":"Neuroscience and Neural Engineering","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12236","display_name":"Photoreceptor and optogenetics research","score":0.9991000294685364,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/glutamate-receptor","display_name":"Glutamate receptor","score":0.8807436227798462},{"id":"https://openalex.org/keywords/excitatory-postsynaptic-potential","display_name":"Excitatory postsynaptic potential","score":0.7793477177619934},{"id":"https://openalex.org/keywords/hippocampus","display_name":"Hippocampus","score":0.646529495716095},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.6427855491638184},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.5406519770622253},{"id":"https://openalex.org/keywords/neurotransmitter","display_name":"Neurotransmitter","score":0.5396859645843506},{"id":"https://openalex.org/keywords/biophysics","display_name":"Biophysics","score":0.44746288657188416},{"id":"https://openalex.org/keywords/microelectrode","display_name":"Microelectrode","score":0.41802719235420227},{"id":"https://openalex.org/keywords/central-nervous-system","display_name":"Central nervous system","score":0.3684103786945343},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.31918421387672424},{"id":"https://openalex.org/keywords/biochemistry","display_name":"Biochemistry","score":0.31135693192481995},{"id":"https://openalex.org/keywords/electrode","display_name":"Electrode","score":0.16106843948364258},{"id":"https://openalex.org/keywords/inhibitory-postsynaptic-potential","display_name":"Inhibitory postsynaptic potential","score":0.09465345740318298},{"id":"https://openalex.org/keywords/receptor","display_name":"Receptor","score":0.07150334119796753}],"concepts":[{"id":"https://openalex.org/C61174792","wikidata":"https://www.wikidata.org/wiki/Q420510","display_name":"Glutamate receptor","level":3,"score":0.8807436227798462},{"id":"https://openalex.org/C112592302","wikidata":"https://www.wikidata.org/wiki/Q1207387","display_name":"Excitatory postsynaptic potential","level":3,"score":0.7793477177619934},{"id":"https://openalex.org/C2781161787","wikidata":"https://www.wikidata.org/wiki/Q48360","display_name":"Hippocampus","level":2,"score":0.646529495716095},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.6427855491638184},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5406519770622253},{"id":"https://openalex.org/C2776219046","wikidata":"https://www.wikidata.org/wiki/Q162657","display_name":"Neurotransmitter","level":3,"score":0.5396859645843506},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.44746288657188416},{"id":"https://openalex.org/C111670793","wikidata":"https://www.wikidata.org/wiki/Q16979465","display_name":"Microelectrode","level":3,"score":0.41802719235420227},{"id":"https://openalex.org/C529278444","wikidata":"https://www.wikidata.org/wiki/Q47273","display_name":"Central nervous system","level":2,"score":0.3684103786945343},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.31918421387672424},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.31135693192481995},{"id":"https://openalex.org/C17525397","wikidata":"https://www.wikidata.org/wiki/Q176140","display_name":"Electrode","level":2,"score":0.16106843948364258},{"id":"https://openalex.org/C17077164","wikidata":"https://www.wikidata.org/wiki/Q1185869","display_name":"Inhibitory postsynaptic potential","level":2,"score":0.09465345740318298},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.07150334119796753},{"id":"https://openalex.org/C147789679","wikidata":"https://www.wikidata.org/wiki/Q11372","display_name":"Physical chemistry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/ner.2017.8008333","is_oa":false,"landing_page_url":"https://doi.org/10.1109/ner.2017.8008333","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2017 8th International IEEE/EMBS Conference on Neural Engineering (NER)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":16,"referenced_works":["https://openalex.org/W249845531","https://openalex.org/W1439525013","https://openalex.org/W1973500410","https://openalex.org/W1994438243","https://openalex.org/W2001458880","https://openalex.org/W2030295531","https://openalex.org/W2030360617","https://openalex.org/W2035150592","https://openalex.org/W2040530215","https://openalex.org/W2042847268","https://openalex.org/W2054683291","https://openalex.org/W2065375190","https://openalex.org/W2076053368","https://openalex.org/W2082474912","https://openalex.org/W2095469984","https://openalex.org/W2342859341"],"related_works":["https://openalex.org/W4253324731","https://openalex.org/W2137815833","https://openalex.org/W4324119913","https://openalex.org/W2242980981","https://openalex.org/W4385062389","https://openalex.org/W2134288827","https://openalex.org/W4242996090","https://openalex.org/W1529334324","https://openalex.org/W1976185190","https://openalex.org/W2216084496"],"abstract_inverted_index":{"In":[0],"our":[1,71],"central":[2],"nervous":[3],"system":[4],"(CNS),":[5],"glutamate":[6,25,44,87,97,102,122,138],"is":[7,20,26],"an":[8,54],"excitatory":[9,88,139],"neurotransmitter":[10],"that":[11],"can":[12],"be":[13],"accumulated":[14],"remarkably":[15],"by":[16,93,109,120],"brain":[17,82],"tissue.":[18],"As":[19],"noticeable":[21],"from":[22,141],"previous":[23],"studies,":[24],"somehow":[27],"closely":[28],"related":[29],"with":[30,58],"most":[31],"ways":[32],"of":[33],"normal":[34,68],"and":[35,62,96,107,117],"abnormal":[36],"cerebral":[37],"activities.":[38],"It":[39],"was":[40,103],"significant":[41],"to":[42,67,85,128,144],"monitor":[43],"concentration":[45],"changes":[46],"in":[47,72,90,113],"vivo":[48,73],"real":[49],"time.":[50],"Therefore,":[51],"we":[52,76],"developed":[53],"enzyme-based":[55],"microelectrode":[56],"array":[57],"high":[59],"sensitivity":[60],"(7.34pA/\u03bcM)":[61],"perfect":[63],"linearity":[64],"(R2=0.999).":[65],"Selectivity":[66],"neurotransmitters":[69],"satisfied":[70],"demands.":[74],"Ultimately,":[75],"applied":[77],"the":[78,81,114,129,137],"electrode":[79],"into":[80],"specific":[83],"tissue":[84],"study":[86],"pathway":[89,140],"hippocampus":[91,100,142],"CA3":[92,101,143],"offside":[94,115],"KCl":[95,111],"stimulating.":[98,123],"The":[99,133],"detected":[104],"about":[105],"18.17\u03bcM":[106],"13.19\u03bcM":[108],"twice":[110,121],"stimulating":[112],"cortex,":[116],"6.50\u03bcM,":[118],"4.55\u03bcM":[119],"All":[124],"peak":[125],"current":[126],"back":[127],"base":[130],"level":[131],"later.":[132],"self-regulation":[134],"ability":[135],"reflects":[136],"cortex.":[145]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1}],"updated_date":"2026-07-29T14:22:42.915294","created_date":"2025-10-10T00:00:00"}