{"id":"https://openalex.org/W1483793504","doi":"https://doi.org/10.1109/ner.2015.7146661","title":"The effect of triggered endocardial neuromodulation decreasing elevated heart rate","display_name":"The effect of triggered endocardial neuromodulation decreasing elevated heart rate","publication_year":2015,"publication_date":"2015-04-01","ids":{"openalex":"https://openalex.org/W1483793504","doi":"https://doi.org/10.1109/ner.2015.7146661","mag":"1483793504"},"language":"en","primary_location":{"id":"doi:10.1109/ner.2015.7146661","is_oa":false,"landing_page_url":"https://doi.org/10.1109/ner.2015.7146661","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2015 7th International IEEE/EMBS Conference on Neural Engineering (NER)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5032086702","display_name":"Antje Pohl","orcid":"https://orcid.org/0000-0001-9995-2228"},"institutions":[{"id":"https://openalex.org/I887968799","display_name":"RWTH Aachen University","ror":"https://ror.org/04xfq0f34","country_code":"DE","type":"education","lineage":["https://openalex.org/I887968799"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Antje Pohl","raw_affiliation_strings":["Department of Cardiovascular and Thoracic Surgery, RWTH Aachen University Hospital, Germany","Medical Information Technology, RWTH Aachen University, Germany"],"affiliations":[{"raw_affiliation_string":"Department of Cardiovascular and Thoracic Surgery, RWTH Aachen University Hospital, Germany","institution_ids":["https://openalex.org/I887968799"]},{"raw_affiliation_string":"Medical Information Technology, RWTH Aachen University, Germany","institution_ids":["https://openalex.org/I887968799"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110552128","display_name":"Jakob Orschulik","orcid":null},"institutions":[{"id":"https://openalex.org/I887968799","display_name":"RWTH Aachen University","ror":"https://ror.org/04xfq0f34","country_code":"DE","type":"education","lineage":["https://openalex.org/I887968799"]},{"id":"https://openalex.org/I4210162505","display_name":"Philips (Germany)","ror":"https://ror.org/05san5604","country_code":"DE","type":"company","lineage":["https://openalex.org/I4210122849","https://openalex.org/I4210162505"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Jakob Orschulik","raw_affiliation_strings":["Philips Chair for Medical Information Technology, RWTH Aachen University, Germany","Medical Information Technology, RWTH Aachen University, Germany"],"affiliations":[{"raw_affiliation_string":"Philips Chair for Medical Information Technology, RWTH Aachen University, Germany","institution_ids":["https://openalex.org/I887968799","https://openalex.org/I4210162505"]},{"raw_affiliation_string":"Medical Information Technology, RWTH Aachen University, Germany","institution_ids":["https://openalex.org/I887968799"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017205267","display_name":"Akram Idrissi","orcid":"https://orcid.org/0000-0003-0642-3218"},"institutions":[{"id":"https://openalex.org/I4210162505","display_name":"Philips (Germany)","ror":"https://ror.org/05san5604","country_code":"DE","type":"company","lineage":["https://openalex.org/I4210122849","https://openalex.org/I4210162505"]},{"id":"https://openalex.org/I887968799","display_name":"RWTH Aachen University","ror":"https://ror.org/04xfq0f34","country_code":"DE","type":"education","lineage":["https://openalex.org/I887968799"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Akram Idrissi","raw_affiliation_strings":["Philips Chair for Medical Information Technology, RWTH Aachen University, Germany","Medical Information Technology, RWTH Aachen University, Germany"],"affiliations":[{"raw_affiliation_string":"Philips Chair for Medical Information Technology, RWTH Aachen University, Germany","institution_ids":["https://openalex.org/I887968799","https://openalex.org/I4210162505"]},{"raw_affiliation_string":"Medical Information Technology, RWTH Aachen University, Germany","institution_ids":["https://openalex.org/I887968799"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109845126","display_name":"Carl Henning Lubba","orcid":null},"institutions":[{"id":"https://openalex.org/I887968799","display_name":"RWTH Aachen University","ror":"https://ror.org/04xfq0f34","country_code":"DE","type":"education","lineage":["https://openalex.org/I887968799"]},{"id":"https://openalex.org/I4210162505","display_name":"Philips (Germany)","ror":"https://ror.org/05san5604","country_code":"DE","type":"company","lineage":["https://openalex.org/I4210122849","https://openalex.org/I4210162505"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Carl H. Lubba","raw_affiliation_strings":["Philips Chair for Medical Information Technology, RWTH Aachen University, Germany","Medical Information Technology, RWTH Aachen University, Germany"],"affiliations":[{"raw_affiliation_string":"Philips Chair for Medical Information Technology, RWTH Aachen University, Germany","institution_ids":["https://openalex.org/I887968799","https://openalex.org/I4210162505"]},{"raw_affiliation_string":"Medical Information Technology, RWTH Aachen University, Germany","institution_ids":["https://openalex.org/I887968799"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048279005","display_name":"Patrick Schauerte","orcid":null},"institutions":[{"id":"https://openalex.org/I887968799","display_name":"RWTH Aachen University","ror":"https://ror.org/04xfq0f34","country_code":"DE","type":"education","lineage":["https://openalex.org/I887968799"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Patrick Schauerte","raw_affiliation_strings":["Department of Internal Medicine I (Cardiology, Pneumology, and Angiology), RWTH Aachen University Hospital, Germany"],"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine I (Cardiology, Pneumology, and Angiology), RWTH Aachen University Hospital, Germany","institution_ids":["https://openalex.org/I887968799"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023948123","display_name":"Nima Hatam","orcid":"https://orcid.org/0000-0002-4466-9959"},"institutions":[{"id":"https://openalex.org/I887968799","display_name":"RWTH Aachen University","ror":"https://ror.org/04xfq0f34","country_code":"DE","type":"education","lineage":["https://openalex.org/I887968799"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Nima Hatam","raw_affiliation_strings":["Department of Cardiovascular and Thoracic Surgery, RWTH Aachen University Hospital, Germany"],"affiliations":[{"raw_affiliation_string":"Department of Cardiovascular and Thoracic Surgery, RWTH Aachen University Hospital, Germany","institution_ids":["https://openalex.org/I887968799"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5060021065","display_name":"Steffen Leonhardt","orcid":"https://orcid.org/0000-0002-6898-6887"},"institutions":[{"id":"https://openalex.org/I4210162505","display_name":"Philips (Germany)","ror":"https://ror.org/05san5604","country_code":"DE","type":"company","lineage":["https://openalex.org/I4210122849","https://openalex.org/I4210162505"]},{"id":"https://openalex.org/I887968799","display_name":"RWTH Aachen University","ror":"https://ror.org/04xfq0f34","country_code":"DE","type":"education","lineage":["https://openalex.org/I887968799"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Steffen Leonhardt","raw_affiliation_strings":["Philips Chair for Medical Information Technology, RWTH Aachen University, Germany","Medical Information Technology, RWTH Aachen University, Germany"],"affiliations":[{"raw_affiliation_string":"Philips Chair for Medical Information Technology, RWTH Aachen University, Germany","institution_ids":["https://openalex.org/I887968799","https://openalex.org/I4210162505"]},{"raw_affiliation_string":"Medical Information Technology, RWTH Aachen University, Germany","institution_ids":["https://openalex.org/I887968799"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5032086702"],"corresponding_institution_ids":["https://openalex.org/I887968799"],"apc_list":null,"apc_paid":null,"fwci":0.6376,"has_fulltext":false,"cited_by_count":6,"citation_normalized_percentile":{"value":0.71388713,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"30","issue":null,"first_page":"470","last_page":"473"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10217","display_name":"Cardiac electrophysiology and arrhythmias","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10217","display_name":"Cardiac electrophysiology and arrhythmias","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10745","display_name":"Heart Rate Variability and Autonomic Control","score":0.9993000030517578,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13381","display_name":"Heart rate and cardiovascular health","score":0.9988999962806702,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/neuromodulation","display_name":"Neuromodulation","score":0.8892253637313843},{"id":"https://openalex.org/keywords/heart-rate","display_name":"Heart rate","score":0.7918680906295776},{"id":"https://openalex.org/keywords/intracardiac-injection","display_name":"Intracardiac injection","score":0.5814727544784546},{"id":"https://openalex.org/keywords/stimulation","display_name":"Stimulation","score":0.5474076271057129},{"id":"https://openalex.org/keywords/blood-pressure","display_name":"Blood pressure","score":0.5066667199134827},{"id":"https://openalex.org/keywords/heart-rate-variability","display_name":"Heart rate variability","score":0.5038456320762634},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.491792231798172},{"id":"https://openalex.org/keywords/cardiology","display_name":"Cardiology","score":0.43965595960617065},{"id":"https://openalex.org/keywords/anesthesia","display_name":"Anesthesia","score":0.40519750118255615},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.3529042601585388}],"concepts":[{"id":"https://openalex.org/C2780375056","wikidata":"https://www.wikidata.org/wiki/Q905905","display_name":"Neuromodulation","level":3,"score":0.8892253637313843},{"id":"https://openalex.org/C2777953023","wikidata":"https://www.wikidata.org/wiki/Q1073121","display_name":"Heart rate","level":3,"score":0.7918680906295776},{"id":"https://openalex.org/C80093799","wikidata":"https://www.wikidata.org/wiki/Q366155","display_name":"Intracardiac injection","level":2,"score":0.5814727544784546},{"id":"https://openalex.org/C24998067","wikidata":"https://www.wikidata.org/wiki/Q4114622","display_name":"Stimulation","level":2,"score":0.5474076271057129},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.5066667199134827},{"id":"https://openalex.org/C71635504","wikidata":"https://www.wikidata.org/wiki/Q933954","display_name":"Heart rate variability","level":4,"score":0.5038456320762634},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.491792231798172},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.43965595960617065},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.40519750118255615},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3529042601585388}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1109/ner.2015.7146661","is_oa":false,"landing_page_url":"https://doi.org/10.1109/ner.2015.7146661","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2015 7th International IEEE/EMBS Conference on Neural Engineering (NER)","raw_type":"proceedings-article"},{"id":"pmh:oai:publications.rwth-aachen.de:561299","is_oa":false,"landing_page_url":"http://publications.rwth-aachen.de/search?p=id:%22RWTH-2015-06755%22","pdf_url":null,"source":{"id":"https://openalex.org/S4306401362","display_name":"RWTH Publications (RWTH Aachen)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I887968799","host_organization_name":"RWTH Aachen University","host_organization_lineage":["https://openalex.org/I887968799"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"2015 7th International IEEE/EMBS Conference on Neural Engineering (NER) : 22 - 24 April 2015, Montpellier, France<br/>7. International IEEE/EMBS Conference on Neural Engineering (NER), NER 2015, Montpellier, France, 2015-04-22 - 2015-04-24","raw_type":"info:eu-repo/semantics/publishedVersion"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.8799999952316284}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":17,"referenced_works":["https://openalex.org/W116116059","https://openalex.org/W1978680171","https://openalex.org/W1984268923","https://openalex.org/W1993415473","https://openalex.org/W2009328775","https://openalex.org/W2030491136","https://openalex.org/W2046225222","https://openalex.org/W2061520159","https://openalex.org/W2101700433","https://openalex.org/W2102797076","https://openalex.org/W2102948895","https://openalex.org/W2145270758","https://openalex.org/W2146561080","https://openalex.org/W2149925244","https://openalex.org/W2314148474","https://openalex.org/W2334756126","https://openalex.org/W6675369874"],"related_works":["https://openalex.org/W2400564179","https://openalex.org/W1964632492","https://openalex.org/W4206905980","https://openalex.org/W2350915185","https://openalex.org/W2356478842","https://openalex.org/W4242170870","https://openalex.org/W2017701310","https://openalex.org/W2136950386","https://openalex.org/W2034163781","https://openalex.org/W1992709230"],"abstract_inverted_index":{"The":[0,91],"heart":[1,23,52,81,132],"rate":[2,24,53,82,133],"is":[3,17],"known":[4],"to":[5,75,137],"be":[6],"an":[7,65,95],"independent":[8],"risk":[9],"factor":[10],"for":[11,21,123],"higher":[12],"overall":[13],"mortality.":[14],"Accordingly,":[15],"there":[16],"a":[18,58,76],"certain":[19],"need":[20],"efficient":[22],"modulation,":[25],"by":[26,34],"means":[27],"of":[28,51,60,79,86,94,147],"pharmacological":[29,43],"approaches":[30,44],"as":[31,33,111],"well":[32],"electrical":[35,84,107],"neuromodulation":[36],"via":[37],"the":[38,80,87,145],"autonomous":[39,88],"nervous":[40,89],"system.":[41,90],"As":[42],"do":[45],"not":[46],"provide":[47],"any":[48],"dynamic":[49],"adjustment":[50],"and":[54,105,118,140],"come":[55],"along":[56],"with":[57],"number":[59],"side":[61],"effects,":[62],"we":[63],"investigate":[64],"alternative":[66],"technique":[67],"called":[68],"cardiac":[69],"neuromodulation.":[70,108],"This":[71],"new":[72],"approach":[73],"aims":[74],"dynamical":[77],"regulation":[78],"through":[83],"stimulation":[85],"first":[92],"results":[93],"in-vivo":[96],"study":[97],"in":[98],"sheep":[99],"(n":[100],"=":[101],"5)":[102],"demonstrating":[103],"safe":[104],"triggered":[106],"Vital":[109],"parameters":[110],"electrocardiograms,":[112],"intracardiac":[113],"electrograms,":[114],"invasive":[115],"blood":[116],"pressure,":[117],"oxygen":[119],"saturation":[120],"are":[121],"recorded":[122],"retrospective":[124],"analysis.":[125],"Results":[126],"show":[127],"that":[128],"during":[129],"neurostimulation":[130],"period,":[131],"decreased":[134],"instantly":[135],"up":[136],"\u2248":[138],"37%":[139],"immediately":[141],"increased":[142],"again":[143],"at":[144],"end":[146],"stimulation.":[148]},"counts_by_year":[{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":1}],"updated_date":"2026-04-04T16:13:02.066488","created_date":"2025-10-10T00:00:00"}